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25-04-2024 | Gastric Cancer | Hollow Organ GI

Deep learning-accelerated T2WI: image quality, efficiency, and staging performance against BLADE T2WI for gastric cancer

Authors: Qiong Li, Wei-Yue Xu, Na-Na Sun, Qiu-Xia Feng, Ya-Jun Hou, Zi-Tong Sang, Zhen-Ning Zhu, Yi-Cheng Hsu, Dominik Nickel, Hao Xu, Yu-Dong Zhang, Xi-Sheng Liu

Published in: Abdominal Radiology

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Abstract

Purpose

The purpose of our study is to investigate image quality, efficiency, and diagnostic performance of a deep learning-accelerated single-shot breath-hold (DLSB) against BLADE for T2-weighted MR imaging (T2WI) for gastric cancer (GC).

Methods

112 patients with GCs undergoing gastric MRI were prospectively enrolled between Aug 2022 and Dec 2022. Axial DLSB-T2WI and BLADE-T2WI of stomach were scanned with same spatial resolution. Three radiologists independently evaluated the image qualities using a 5-scale Likert scales (IQS) in terms of lesion delineation, gastric wall boundary conspicuity, and overall image quality. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated in measurable lesions. T staging was conducted based on the results of both sequences for GC patients with gastrectomy. Pairwise comparisons between DLSB-T2WI and BLADE-T2WI were performed using the Wilcoxon signed-rank test, paired t-test, and chi-squared test. Kendall’s W, Fleiss' Kappa, and intraclass correlation coefficient values were used to determine inter-reader reliability.

Results

Against BLADE, DLSB reduced total acquisition time of T2WI from 495 min (mean 4:42 per patient) to 33.6 min (18 s per patient), with better overall image quality that produced 9.43-fold, 8.00-fold, and 18.31-fold IQS upgrading against BALDE, respectively, in three readers. In 69 measurable lesions, DLSB-T2WI had higher mean SNR and higher CNR than BLADE-T2WI. Among 71 patients with gastrectomy, DLSB-T2WI resulted in comparable accuracy to BLADE-T2WI in staging GCs (P > 0.05).

Conclusions

DLSB-T2WI demonstrated shorter acquisition time, better image quality, and comparable staging accuracy, which could be an alternative to BLADE-T2WI for gastric cancer imaging.

Graphical abstract

Appendix
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Metadata
Title
Deep learning-accelerated T2WI: image quality, efficiency, and staging performance against BLADE T2WI for gastric cancer
Authors
Qiong Li
Wei-Yue Xu
Na-Na Sun
Qiu-Xia Feng
Ya-Jun Hou
Zi-Tong Sang
Zhen-Ning Zhu
Yi-Cheng Hsu
Dominik Nickel
Hao Xu
Yu-Dong Zhang
Xi-Sheng Liu
Publication date
25-04-2024
Publisher
Springer US
Published in
Abdominal Radiology
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-024-04323-7
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