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Open Access 01-12-2023 | Commentary

Further considerations for placebo controls in surgical trials

Authors: Marion K. Campbell, David J. Beard, Jane M. Blazeby, Sian Cousins, the ASPIRE group

Published in: Trials | Issue 1/2023

Abstract

The use of invasive placebo controls in surgical trials can be challenging. The ASPIRE guidance, published in the Lancet in 2020, provided advice for the design and conduct of surgical trials with an invasive placebo control. Based on a more recent international expert workshop in June 2022, we now provide further insights into this topic. These include the purpose and design of invasive placebo controls, patient information provision and how findings from these trials may be used to inform decision-making.

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Title: Further considerations for placebo controls in surgical trials
Authors: Marion K. Campbell
David J. Beard
Jane M. Blazeby
Sian Cousins
the ASPIRE group
Publication date: 01-12-2023
Publisher: BioMed Central
Published in: Trials / Issue 1/2023
Electronic ISSN: 1745-6215
DOI: https://doi.org/10.1186/s13063-023-07417-7

2024 ESC Congress

Springer Medicine

Further considerations for placebo controls in surgical trials

Abstract

2024 ESC Congress

Springer Medicine

Abstract

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