06-09-2024 | Francisella Tularensis | Brief Report
Two cases of Francisella tularensis subspecies holartica prosthetic valve endocarditis, and review of the literature
Published in: European Journal of Clinical Microbiology & Infectious Diseases
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Francisella tularensis endocarditis is rare and difficult to diagnose, and only a few cases have been described. We report two new cases of endocarditis due to F. tularensis subsp. holarctica, with a favorable evolution after appropriate antibiotic therapy and valve replacement surgery, and review the 5 other cases reported in the literature. This rare infection may be suspected based on the local epidemiology and the patient’s exposure factors. A regimen of ciprofloxacin and gentamicin, combined with surgical valve replacement if necessary, appears to be effective in treating F. tularensis endocarditis.
