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A rare case of multiple myeloma with double translocations: t(11;14) and t(14;16)

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Abstract

Multiple myeloma is a clonal plasma cell malignancy often characterized by complex cytogenetic abnormalities that influence prognosis and treatment strategies. This report describes a 63-year-old male with kappa light chain multiple myeloma and a rare finding of double translocation involving t(11;14) and t(14;16), detected by FISH analysis. This case emphasizes the clinical implications of such genetic abnormalities and their impact on disease progression and therapeutic decisions.
Title
A rare case of multiple myeloma with double translocations: t(11;14) and t(14;16)
Authors
Mina Meseha
Vishw Patel
Kirolos Sekla
Ping Yang
David Coffey
Publication date
01-12-2025
Publisher
Springer Berlin Heidelberg
Published in
Journal of Hematopathology / Issue 1/2025
Print ISSN: 1868-9256
Electronic ISSN: 1865-5785
DOI
https://doi.org/10.1007/s12308-025-00626-w
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