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26-07-2023 | Original Paper

Feasibility, Acceptability and Appropriateness of MedViewer: A Novel Hair-Based Antiretroviral Real-Time Clinical Monitoring Tool Providing Adherence Feedback to Patients and Their Providers

Authors: Carol E. Golin, Elias P. Rosen, Ella Gillespie Ferguson, Nzi Rose Perry, Amanda Jacqueline Poliseno, Alexandra J. Munson, Alexandra Davis, Lauren M. Hill, Jessica Keys, Nicole R. White, Claire E. Farel, Angela Kashuba

Published in: AIDS and Behavior | Issue 12/2023

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Abstract

Antiretroviral therapy (ART) adherence is key to achieving viral load suppression and ending the HIV epidemic but monitoring and supporting adherence using current interventions is challenging. We assessed the feasibility, acceptability and appropriateness of MedViewer (MV), a novel intervention that provides real-time adherence feedback for patients and providers using infra-red matrix-assisted laser desorption electrospray ionization (IR-MALDESI) for mass spectrometry imaging of daily ART concentrations in patients’ hair. We used mixed methods to feasibility test MV at a busy Infectious Diseases (ID) clinic, enrolling 16 providers and 36 patients. Providers underwent standardized training; patients and providers watched an 8-min informational video about MV. We collected patient and provider data at baseline and within 24 h of clinic visits and, with patients, approximately 1 month after clinic visits. MedViewer was feasible, liked by patients and providers, and perceived to help facilitate adherence conversations and motivate patients to improve adherence.
Trial Registration: NCT04232540.
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Metadata
Title
Feasibility, Acceptability and Appropriateness of MedViewer: A Novel Hair-Based Antiretroviral Real-Time Clinical Monitoring Tool Providing Adherence Feedback to Patients and Their Providers
Authors
Carol E. Golin
Elias P. Rosen
Ella Gillespie Ferguson
Nzi Rose Perry
Amanda Jacqueline Poliseno
Alexandra J. Munson
Alexandra Davis
Lauren M. Hill
Jessica Keys
Nicole R. White
Claire E. Farel
Angela Kashuba
Publication date
26-07-2023
Publisher
Springer US
Published in
AIDS and Behavior / Issue 12/2023
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-023-04104-1

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