04-01-2025 | Eosinophilic Esophagitis | Clinical Conundrum
An Unusual Finding in a Patient with Dysphagia
Authors:
Clara Benedetta Conti, MD, Giacomo Mulinacci, MD, Davide Seminati, MD, Nicola Zucchini, MD
Published in:
Dysphagia
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Excerpt
A sinhalese man was referred by the General Practitioner for upper gastrointestinal endoscopy. He reported a recent onset of dysphagia for solid food. No other relevant gastrointestinal or general symptoms. He had been empirically treated with proton pump inhibitors (PPIs), without benefits. His past medical history included hypercholesterolemia, managed with atorvastatin, and allergic asthma. He had no family history for gastrointestinal or immune-related disorders. Laboratory tests showed a white cell count of 5.62 × 10⁹/L (reference range: 4.0–11.0), hemoglobin of 16.2 g/dL (reference range: 14–18), and platelets of 480 × 10⁹/L (reference range: 154–440). A gastroscopy was performed and revealed the presence of a sessile polyp of 15 mm at the gastroesophageal junction (Fig.
1). Macroscopically, the remaining oesophageal mucosa was normal, as well as the gastric and duodenal mucosa. Biopsies of the polyp were taken, together with biopsies of the distal, mid, and cervical esophageal mucosa. …