Lactobacillus plantarum liver abscess following ERCP: a case report and review
- Open Access
- 01-12-2025
- Endoscopic Retrograde Cholangiopancreatography
- Case Report
- Authors
- Wenjing Ren
- Yuran Wei
- Guanping Lian
- Chuwei Yang
- Yufei Liu
- Published in
- BMC Infectious Diseases | Issue 1/2025
Abstract
Background
Lactobacillus plantarum is a probiotic. It has a positive effect on the intestinal flora, improving intestinal barrier function and regulating immune function. At present, it is clinically used to prevent or treat a variety of diseases. However, in recent years, serious infections caused by Lactobacillus plantarum have been reported. Endoscopic retrograde cholangiopancreatography (ERCP) is one of the main methods for managing biliary and pancreatic disorders. With the widespread application of ERCP, there are increasing reports of concurrent infections.
Case presentation
In this case, a 62-year-old female patient with pancreatic cancer developed chills and fever after undergoing ERCP and biliary stenting. She was diagnosed with a liver abscess, and the pathogenic bacterium identified was Lactobacillus plantarum, a rare instance of a probiotic causing disease.
Conclusion
This report describes the first case of a liver abscess caused by Lactobacillus plantarum following ERCP. This suggests that although Lactobacillus plantarum is a probiotic, it is risky for patients with anatomical disruptions, impaired mucosal barrier function, or immunocompromised status. Clinical applications of Lactobacillus plantarum should be treated with caution.
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- Title
- Lactobacillus plantarum liver abscess following ERCP: a case report and review
- Authors
-
Wenjing Ren
Yuran Wei
Guanping Lian
Chuwei Yang
Yufei Liu
- Publication date
- 01-12-2025
- Publisher
- BioMed Central
- Published in
-
BMC Infectious Diseases / Issue 1/2025
Electronic ISSN: 1471-2334 - DOI
- https://doi.org/10.1186/s12879-025-11094-z
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