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Endocrine Pathology

Issue 4/2024

Content (19 Articles)

Consensus Statement: Recommendations on Actionable Biomarker Testing for Thyroid Cancer Management

Ozgur Mete, Andrée Boucher, Kasmintan A. Schrader, Omar Abdel-Rahman, Houda Bahig, Cheryl Ho, Olfat Kamel Hasan, Bernard Lemieux, Eric Winquist, Ralph Wong, Jonn Wu, Nicole Chau, Shereen Ezzat

Correction: Consensus Statement: Recommendations on Actionable Biomarker Testing for Thyroid Cancer Management

Ozgur Mete, Andrée Boucher, Kasmintan A. Schrader, Omar Abdel-Rahman, Houda Bahig, Cheryl Ho, Olfat Kamel Hasan, Bernard Lemieux, Eric Winquist, Ralph Wong, Jonn Wu, Nicole Chau, Shereen Ezzat

Rapid Evolution of Metastases in Patients with Treated G3 Neuroendocrine Tumors Associated with NEC-Like Transformation and TP53 Mutation

Atsuko Kasajima, Nicole Pfarr, Eva-Maria Mayr, Ayako Ura, Elisa Moser, Alexander von Werder, Abbas Agaimy, Marianne Pavel, Günter Klöppel

Progression of Low-Grade Neuroendocrine Tumors (NET) to High-Grade Neoplasms Harboring the NEC-Like Co-alteration of RB1 and TP53

Nancy M. Joseph, Sarah E. Umetsu, Grace E. Kim, Merryl Terry, Arie Perry, Emily Bergsland, Sanjay Kakar

High-Grade Progression, Sarcomatous Transformation, and/or Metastasis of Pituitary Neuroendocrine Neoplasms (PitNENs): The UCSF Experience

Merryl Terry, Minh P. Nguyen, Vivian Tang, Ekin Guney, Krishna L. Bharani, Sonika Dahiya, Ondrej Choutka, Ewa Borys, Gerald Reis, Lewis Blevins, Manish K. Aghi, Sandeep Kunwar, John DeGroot, David R. Raleigh, Melike Pekmezci, Andrew W. Bollen, Soonmee Cha, Nancy M. Joseph, Arie Perry

Glucagon-Producing Pancreatic Neuroendocrine Tumors (Glucagonomas) are Enriched in Aggressive Neoplasms with ARX and PDX1 Co-expression, DAXX/ATRX Mutations, and ALT (Alternative Lengthening of Telomeres)

Paola Mattiolo, Michele Bevere, Andrea Mafficini, Anna Vera D. Verschuur, Martina Calicchia, Wenzel M. Hackeng, Michele Simbolo, Salvatore Paiella, Koen M. A. Dreijerink, Luca Landoni, Serena Pedron, Sara Cingarlini, Roberto Salvia, Michele Milella, Rita T. Lawlor, Gerlof D. Valk, Menno R. Vriens, Aldo Scarpa, Lodewijk A. Brosens, Claudio Luchini

Clinicopathological Features of Epstein-Barr Virus-Positive Neuroendocrine Carcinoma: Analysis of Twenty-Two Cases

Xiao-Ying Zhang, Jia Fu, Mei-Ling Chen, Xin-Chun Chen, Shi-Min Zhang, Yi-Ling Luo, Mao Fang, Han-Wen Jiang, Fang Chen, Hao Wang, Jin-Hua He, Yan Li

Effective Preparation of FFPE Tissue Samples for Preserving Appropriate Nucleic Acid Quality for Genomic Analysis in Thyroid Carcinoma

Yoichiro Okubo, Nagisa Toyama, Rika Kasajima, Soji Toda, Hiroyuki Hayashi, Emi Yoshioka, Kota Washimi, Shinya Sato, Yukihiko Hiroshima, Chie Hasegawa, Shu Yuguchi, Mei Kadoya, Hiroto Narimatsu, Katsuhiko Masudo, Hiroyuki Iwasaki, Tomoyuki Yokose, Yohei Miyagi

The Potential Utility of RAS Q61R Immunohistochemistry as a Screening Tool in Pre-operative Fine Needle Aspirates of Medullary Thyroid Carcinoma

  • Research

Brea Deyette, Daniel J. Lubin, Aswathy M. Cheriyan, Amy Sheen, Peter M. Sadow, Anthony J. Gill, Kartik Viswanathan

Clinicopathologic and Molecular Analysis of 15 Pediatric and Young Adult Patients with High-Grade Non-anaplastic Thyroid Carcinoma

Rumeal D. Whaley, Sounak Gupta, Matthew C. Manninen, Daniel R. O’Brien, Lori A. Erickson

Catching the Silent Culprits: TERT Promoter Mutation Screening of Minimally Invasive Follicular and Oncocytic Thyroid Carcinoma in Clinical Practice

L. Samuel Hellgren, Adam Stenman, Kenbugul Jatta, Vincenzo Condello, Catharina Larsson, Jan Zedenius, C. Christofer Juhlin

Unravelling the Reasons Behind Limited Response to Anti-PD Therapy in ATC: A Comprehensive Evaluation of Tumor-Infiltrating Immune Cells and Checkpoints

  • Research

Monikongkona Boruah, Shipra Agarwal, Riyaz Ahmad Mir, Saumitra Dey Choudhury, Kapil Sikka, Sameer Rastogi, Nishikant Damle, Mehar C. Sharma

SATB2 is an Emergent Biomarker of Anaplastic Thyroid Carcinoma: A Series with Comprehensive Biomarker and Molecular Studies

Dingani Nkosi, William E. Crowe, Brian J. Altman, Zoltán N. Oltvai, Ellen J. Giampoli, Moises J. Velez

Mitochondrial Proteome Defined Molecular Pathological Characteristics of Oncocytic Thyroid Tumors

  • Research

Lu Li, Likun Zhang, Wenhao Jiang, Zhiqiang Gui, Zhihong Wang, Hao Zhang, Yi He, Yi Zhu, Tiannan Guo, Haixia Guan, Zhiyan Liu, Yaoting Sun, Jianqing Gao

Keynote webinar | Spotlight on progress in colorectal cancer

  • Live
  • Webinar | 11-12-2025 | 18:00 (CET)

CRC remains a major global health burden, but advances in screening, treatment, and lifestyle-based prevention continue to reshape clinical practice. Gain insights into how the latest research can be leveraged to optimize patient care across the CRC continuum.

Watch it live: Thursday 11 December 2025, 18:00-19:30 (CET)

Prof. Antoni Castells
Prof. Edward Giovannucci
Prof. Harpreet Wasan
Join the webinar
Webinar

Keynote webinar | Spotlight on functional neurological disorder

FND perplexes and frustrates patients and physicians alike. Limited knowledge and insufficient awareness delays diagnosis and treatment, and many patients feel misunderstood and stigmatized. How can you recognize FND and what are the treatment options?

Prof. Mark Edwards
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Video
Image Credits
Colon cancer illustration/© (M) KATERYNA KON / SCIENCE PHOTO LIBRARY / Getty Images, Human brain illustration/© (M) CHRISTOPH BURGSTEDT / SCIENCE PHOTO LIBRARY / Getty Images