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29-01-2024 | Electroencephalography | Case Report

Super-selective Wada test for pre-surgical leg motor function assessment: A case report

Authors: Alexander Kuruvilla, Charles J. Sadle, Ian Mutchnick, Samir Karia, Jeetendra Sah, Rebecca Stilp, Shervin Dashti, Cemal Karakas

Published in: Child's Nervous System | Issue 5/2024

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Abstract

Introduction

Wada test is well-known to assess lateralization of memory and language functions; however, super-selective Wada (ss-Wada) to evaluate motor leg function is rare. We present a ss-Wada test within the anterior cerebral artery (ACA) to assess the motor function of the leg.

Methods

Retrospective chart review.

Results

Comprehensive phase-I/II surgical evaluation revealed an ictal focus around the left post-central gyrus with immediate involvement around the left para-central regions. To avoid potential right leg motor dysfunction with the surgery, the patient underwent a ss-Wada procedure. Angiography revealed bilateral ACAs were supplied by the left A1 segment. Super-selective microcatheter injection of amobarbital into the left ACA was performed to avoid cross-filling the contralateral ACA. The ss-Wada test confirmed no right leg motor impairment. Afterward, a craniotomy with direct cortical stimulation confirmed that the left-sided ictal/peri-ictal zone had no clear leg motor function. The patient underwent disconnection of that region and remained seizure-free at 10-month post-op follow-up without any motor or sensory deficits in the right limbs.

Conclusion

This case demonstrates the proof of concept for ss-Wada in assessing lower extremity motor function. The ss-Wada procedure accurately predicted no motor deficits in the right leg, consistent with preserved motor function post-surgery.
Literature
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Metadata
Title
Super-selective Wada test for pre-surgical leg motor function assessment: A case report
Authors
Alexander Kuruvilla
Charles J. Sadle
Ian Mutchnick
Samir Karia
Jeetendra Sah
Rebecca Stilp
Shervin Dashti
Cemal Karakas
Publication date
29-01-2024
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 5/2024
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-024-06302-1

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