EAN 2025

Serum neurofilament light chain may predict relapse in patients with multiple sclerosis up to a year in advance.

Patients with Parkinson disease who carry mutations in LRRK2 may be more susceptible to certain cancers than their peers without this genetic mutation.

Real-world data suggest that early escalation of therapy for patients with generalized myasthenia gravis may result in faster and more consistent improvement in symptoms.

Nocturnal, sleep, and wake heart rate variability may be a relevant marker for neurological and psychiatric diseases, suggesting sleep plays a potential role in brain health.

Timing of anticoagulation therapy after decompressive surgery does not significantly influence the risk of new bleeding or venous thrombotic events or disability.

Patients with dementia who fracture their hip have significantly higher mortality rates than those without dementia, especially patients with Parkinson dementia in the first 4 months after surgery.

A meta-analysis of phase 3 clinical trials indicates that anti-amyloid monoclonal antibodies have significantly lower efficacy in female than in male patients for the treatment of Alzheimer disease.

A higher number of infratentorial lesions, presence of spinal cord lesions, greater volume of the choroid plexus, and lower volume of the thalamus predict long-term outcomes in children with multiple sclerosis.

Increasing evidence points to the role of the glymphatic system in pathological protein accumulation that occurs in ALS and other motor neuron diseases.

Use of ChatGPT-4o can help bridge expertise gaps between specialist and non-specialist neurologists diagnosing polyneuropathies, but human verification is still needed.

Cluster headache remission often begins around 55 years of age, with a large age variation among patients.

A new diagnostic method based on real-time MRI and quantitative muscle ultrasound can distinguish between different phenotypes of dysphagia.