Skip to main content
Key Specialties
Anesthesiology Cardiology Dermatology Diabetology Endocrinology Gastroenterology General Medicine Geriatrics Hematology Infectious Diseases Internal Medicine Nephrology Neurology Obstetrics and Gynecology Oncology Ophthalmology Pediatrics Psychiatry Radiology Respiratory Medicine Rheumatology Surgery Urology
Congress Coverage
ASH 2024 Annual Meeting 2024 ESMO Congress 2024 ERS Congress 2024 EASD Congress 2024 ESC Congress 2024 EAN Congress 2024 ASCO Annual Meeting 2024 ACC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on adolescent vaping

LIVE: Wednesday 29th January, 18:00-19:30 CET

Growing numbers of young people are using e-cigarettes, despite warnings of respiratory effects and addiction. How can doctors tackle the epidemic, and what health effects should you prepare to manage in your clinics?
ADVANCED SEARCH
Log in
Top

Discover Oncology

Issue 1/2024

Content (849 Articles)

Exploring the relationship between immune heterogeneity characteristic genes of rheumatoid arthritis and acute myeloid leukemia

Chengzhi Jiang, Wenjuan Jiang, Pengtao Liu, Wenxue Sun, Wenjie Teng

Associations between HIFs and tumor immune checkpoints: mechanism and therapy

Jiayu Liu, Ying Jiang, Lingyan Chen, Zhiwen Qian, Yan Zhang

Suppression of the long non-coding RNA LINC01279 triggers autophagy and apoptosis in lung cancer by regulating FAK and SIN3A

Jiancong Wu, Xiaobi Huang, Xiaofang Li, Honglian Zhou, Xiaorao Chen, Yongyang Chen, Yudong Guo, Jian Huang, Hanqing Huang, Zhong Huang, Guoan Chen, Zhixiong Yang, Jian Zhang, Wenmei Su

The relationship between physical activity, self-efficacy and quality of life in colorectal cancer survivors: a multicenter cross-sectional study

Yuru Hu, Lijun Wang, Guoqiang Su, Bo Chen, Zheng Ruan, Jinqiu Yang, Qu Shen

  • Open Access
  • Comment

Vitality, viability, long-term clonogenic survival, cytotoxicity, cytostasis and lethality: what do they mean when testing new investigational oncology drugs?

Benjamin N. Forgie, Rewati Prakash, Alicia A. Goyeneche, Carlos M. Telleria

P129, a pyrazole ring-containing isolongifolanone-derivate: synthesis and investigation of anti-glioma action mechanism

Yining Jiang, Yunyun Wang, Liyan Zhao, Wenzhuo Yang, Lin Pan, Yang Bai, Yubo Wang, Yunqian Li

A novel cholesterol metabolism-related ferroptosis pathway in hepatocellular carcinoma

Weiwei Fang, Jianyong Liu, Fanguo Zhang, Cheng Pang, Xiying Li

GLUD1 inhibits hepatocellular carcinoma progression via ROS-mediated p38/JNK MAPK pathway activation and mitochondrial apoptosis

Qianwei Zhao, Mengdan Yu, Jinxia Li, Yaoyu Guo, Zexuan Wang, Kefei Hu, Fang Xu, Yixian Liu, Lili Li, Didi Wan, Ying Zhao, Jian Shang, Jintao Zhang

Low expression of PRRG2 in kidney renal clear cell carcinoma: an immune infiltration-associated prognostic biomarker

Gonglin Tang, Guixin Ding, Gang Wu, Xiaofeng Wang, Tianqi Wang, Qingsong Zou, Kai Sun, Jitao Wu

Genomic and transcriptomic profiling of hepatocellular carcinoma reveals a rare molecular subtype

Mengting Zhu, Valentina Rovella, Manuel Scimeca, Alessandro Mauriello, Yufang Shi, Julia Bischof, Jonathan Woodsmith, Alessandro Anselmo, Gerry Melino, Giuseppe Tisone, Massimiliano Agostini

Breast cancer cells and adipocytes in hypoxia: metabolism regulation

Xin Yu, Tianqi Zhang, Xiaozhi Cheng, Li Ma

Anti-prostate cancer mechanism of black ginseng during the "nine steaming and nine sun-drying" process based on HPLC analysis combined with vector space network pharmacology

Youran Zhang, Ye Huang, Deqiang Dou

The role of stromal cells in epithelial–mesenchymal plasticity and its therapeutic potential

Juanjing Wang, Junmei Peng, Yonglin Chen, M. I. Nasser, Hui Qin

CircUCK2 promotes hepatocellular carcinoma development by upregulating UCK2 in a mir-149-5p-dependent manner

Minghai Shen, Qinghua Zhang, Wanneng Pan, Bei Wang

  • Open Access
  • Research

Correlation of DNA methylation of DNMT3A and TET2 with oral squamous cell carcinoma

Xueming Li, Zaikun Li, Qingxi Gao, Yanan Peng, Yang Yu, Tenglong Hu, Wei Wang

Mitochondrial-mediated apoptosis as a therapeutic target for FNC (2′-deoxy-2′-b-fluoro-4′-azidocytidine)-induced inhibition of Dalton’s lymphoma growth and proliferation

Naveen Kumar, Sanjeev Kumar, Alok Shukla, Sanjay Kumar, Rishi Kant Singh, Ilya Ulasov, Sandeep Kumar, Anand Kumar Patel, Lokesh Yadav, Ruchi Tiwari, Rachana, Shivashish Priyadarshi Mohanta, Kaushalendra, Vikram Delu, Arbind Acharya

Late effects of high-dose methotrexate in childhood cancer survivors: a Swiss single centre observational study

Kevin Brunold, Maria Otth, Katrin Scheinemann

  • Open Access
  • Correction

Correction: Treatment outcomes of radiotherapy with concurrent weekly cisplatin in older patients with locally advanced head and neck squamous cell carcinoma

Yusuke Uchinami, Koichi Yasuda, Satoshi Kano, Manami Otsuka, Seijiro Hamada, Takayoshi Suzuki, Nayuta Tsushima, Shuhei Takahashi, Yoshihiro Fujita, Tomohiko Miyazaki, Hajime Higaki, Jun Taguchi, Yasushi Shimizu, Tomohiro Sakashita, Akihiro Homma, Hidefumi Aoyama

Clinical importance of serum miRNA levels in breast cancer patients

Fatih Turkoglu, Akin Calisir, Bahadir Ozturk

Long-term neurotoxicity among childhood acute lymphoblastic leukaemia survivors enrolled between 1971 and 1998 in EORTC Children Leukemia Group studies

Maëlle de Ville de Goyet, Michal Kicinski, Stefan Suciu, Els Vandecruys, Anne Uyttebroeck, Alina Ferster, Claire Freycon, Geneviève Plat, Caroline Thomas, Mélissa Barbati, Marie-Françoise Dresse, Catherine Paillard, Claire Pluchart, Pauline Simon, Christophe Chantrain, Odile Minckes, Jutte van der Werff ten Bosch, Yves Bertrand, Pierre Rohrlich, Frederic Millot, Robert Paulus, Yves Benoit, Caroline Piette

Construction and in vitro evaluation of pH-sensitive nanoparticles to reverse drug resistance of breast cancer stem cells

Weinan Li, Yuhan Fu, Jialin Sun, Hexin Gong, Ru Yan, Yanhong Wang

  • Open Access
  • Review

Exploring the frontiers: tumor immune microenvironment and immunotherapy in head and neck squamous cell carcinoma

Shaokun Liu, Ru Wang, Jugao Fang

Characterization of hypoxia-responsive states in ovarian cancer to identify hot tumors and aid adjuvant therapy

Minghui Cao, Liwei Xiao, Shuo Chen, Jiaming Huang

A bibliometric and visualized in oral microbiota and cancer research from 2013 to 2022

Zhiyu Gu, Yunkun Liu

RPN1 promotes the proliferation and invasion of breast cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Wei-juan Shen, Yi Zhang

PLCD3 inhibits apoptosis and promotes proliferation, invasion and migration in gastric cancer

Yantao Yu, Shantanu Baral, Qiannan Sun, Jianyue Ding, Qi Zhang, Fanyu Zhao, Shuyang Gao, Qing Yao, Haoyue Yu, Bin Liu, Daorong Wang

Hypofractionated versus conventional fractionation external beam radiotherapy in intermediate and high risk localized prostate cancer

Eileen Samuel, Saliha Zaman, Muhammad Abu Bakar, Muhammad Mohsin Fareed

APOB is a potential prognostic biomarker in hepatocellular carcinoma

Zhifeng Lin, Xiaohui Ji, Nana Tian, Yu Gan, Li Ke

CT imaging features of lung ground-glass nodule patients with upgraded intraoperative frozen pathology

Hongya Wang, Aiping Chen, Kun Wang, He Yang, Wei Wen, Qianrui Ren, Liang Chen, Xinfeng Xu, Quan Zhu

Analysis of clinical characteristics, treatment patterns, and outcome of patients with bilateral testicular germ cell tumors

Hoffman Azik, Nativ Omri, Malshy Kamil, Haifler Miki, Golan Shay, Mano Roy, Freifeld Yuval, Rosenzweig Barak, Shalom Ben, Stabholz Yariv, Ben-David Reuven, Amiel E. Gilad

Research progress of Paris polyphylla in the treatment of digestive tract cancers

Jia Wang, Bao-yi Ni, Jing Wang, Lei Han, Xin Ni, Xin-miao Wang, Lu-chang Cao, Qian-hui Sun, Xin-pu Han, Hu-jun Cui

The role of tumor parenchyma and brain cortex signal intensity ratio in differentiating solitary fibrous tumors and meningiomas

Yue Yu, Fang Gu, Yi-Lin Luo, Shi-Guang Li, Xiao-Feng Jia, Liang-Xian Gu, Guo-Ping Zhang, Xin Liao

  • Open Access
  • Review

Research progress of exosomes in the angiogenesis of digestive system tumour

Yuan Liu, Hao Wu, Yaodong Sang, Wei Chong, Liang Shang, Leping Li

Analysis of factors related to osteoporotic vertebral fracture in prostate cancer patients

Shunfa Huang, Lilan Wu, Shuting Lin, Siqing Cai, Jianjun Zhou

A novel prognostic model of breast cancer based on cuproptosis-related lncRNAs

Feixiang Li, Yongyan Yang, Xuan Zhang, Jiafeng Yu, Yonghao Yu

  • Open Access
  • Research

Expression of FOXI1 and POU2F3 varies among different salivary gland neoplasms and is higher in Warthin tumor

Masahito Hoki, Yosuke Yamada, Emi Hiratomo, Masahiro Hirata, Yasuhide Takeuchi, Masayoshi Yoshimatsu, Masahiro Kikuchi, Yo Kishimoto, Alexander Marx, Hironori Haga

  • Open Access
  • Research

The endoplasmic reticulum stress-related genes and molecular typing predicts prognosis and reveals characterization of tumor immune microenvironment in lung squamous cell carcinoma

Ruolan Wang, Yanhua Huang, Juan He, Shan Jin, Xin Li, Kun Tan, Wei Xia

Real-world prognostic significance of attaining minimal residual disease negativity in newly diagnosed multiple myeloma

Jing Wang, Jing Li, Run Zhang, Jianyong Li, Lijuan Chen, Yuanyuan Jin

Histological types of brain tumors diagnosed at the Kenyatta National Hospital between 2016 and 2019: a retrospective study

Samwel Rema Gesaka, Parmenas Minda Okemwa, Philip Maseghe Mwachaka

Feasibility analysis of arterial CT radiomics model to predict the risk of local and metastatic recurrence after radical cystectomy for bladder cancer

Huawang Lv, Xiaozhou Zhou, Yuan Liu, Yuting Liu, Zhiwen Chen

Delineating the role of nuclear receptors in colorectal cancer, a focused review

Mukesh Kumar Manickasamy, Sujitha Jayaprakash, Sosmitha Girisa, Aviral Kumar, Hiu Yan Lam, Elena Okina, Huiyan Eng, Mohammed S. Alqahtani, Mohamed Abbas, Gautam Sethi, Alan Prem Kumar, Ajaikumar B. Kunnumakkara

Identifying the tumor immune microenvironment-associated prognostic genes for prostate cancer

Shi Zong, Ji Gao

Concomitant double-fusion of PLEKHA7-ALK and INPP5D-ALK reveals favorable alectinib sensitivity in lung adenocarcinoma: a case report and literature review

Pei Li, Xiao Ju, Guangjian Yang

Should we consider Systemic Inflammatory Response Index (SIRI) as a new diagnostic marker for rectal cancer?

Hilmi Yazici, Ayse Eren Kayaci, Halil Ibrahim Sevindi, Wafi Attaallah

  • Open Access
  • NSCLC
  • Research

TRAIL predisposes non-small cell lung cancer to ferroptosis by regulating ASK-1/JNK1 pathway

Xiaofang Liu, Huiqian Deng, Mi Huang, Wei Zhou, Yilin Yang

Modulation of intestinal metabolites by calorie restriction and its association with gut microbiota in a xenograft model of colorectal cancer

Yuhuan Zhang, Lintao Dong, Xingchen Dai, Yongli Huang, Yujing Gao, Fang Wang

  • Open Access
  • Research

Comprehensive pan-carcinoma analysis of ITGB1 distortion and its potential clinical significance for cancer immunity

Yuchang Fei, Yulun Wu, Luting Chen, Huan Yu, Lei Pan

Visual conservation treatment dilemmas in neuroblastoma with bilateral blindness

Haiyan Cheng, Yu Lin, Wei Yang, Xiaofeng Chang, Jun Feng, Shen Yang, Shan Liu, Tong Yu, Xiaojiao Peng, Panpan Zheng, Chengyue Zhang, Haiwei Jia, Hong Qin, Huanmin Wang

Prognostic significance of LINC01132 in lung cancer and its regulatory role in tumor progression

Yang Hu, Youying Wei

Current and future of immunotherapy for thyroid cancer based on bibliometrics and clinical trials

Ke Wang, Ying Zhang, Yang Xing, Hong Wang, Minghua He, Rui Guo

Expression and prognosis analysis of TBX2 subfamily in human lung carcinoma

Rui Mi, Qiubo Wang, Qingyang Liu, Fengying Jiang, Yuan Ji

  • Open Access
  • Research

The mechanism of action and experimental verification of Gan-song Yin on renal clear cell carcinoma based on network pharmacology and bioinformatics

Wenjie Jiang, Ling Yuan, Qian Liu, Xiangyang Li, Yifan Yang, Jiaqing Li, Taiqiang Jiao, Yang Niu, Lei Zhang, Hongli Dou, Yi Nan

Comprehensive analysis of DNA methylation gene expression profiles in GEO dataset reveals biomarkers related to malignant transformation of sinonasal inverted papilloma

Li Mu, Shun Hu, Guoping Li, Ping Wu, Ke Zheng, Sheng Zhang

The impact of different clinicopathologic factors and salvage therapies on cervical cancer patients with isolated para-aortic lymph node recurrence

Chenyan Fang, Yinfeng Zhu, Ping Zhang, Tao Zhu, Yingli Zhang

Effects of different surgical approaches on health-related quality of life in pediatric and adolescent patients with papillary thyroid carcinoma

Yanling Su, Feng Wang, Shunjin Chen, Xiyu Yao

  • Open Access
  • Research

Comprehensive analysis of T cell exhaustion related signature for predicting prognosis and immunotherapy response in HNSCC

Wei Zhang, Mei Qu, Chun Yin, Zhiliang Jin, Ya Hu

The prognostic value of LAYN in HPV-related head and neck squamous cell carcinoma and its influence on immune cell infiltration

Qingjuan Chen, Jiankang Chen, Zuzhuang Lu, Rui Nian, Wanjun Li, Zhongqiang Yao, Shangdong Mou, Ying Liu, Xia Cao, Wenjing He, Chenjing Zhu

Causal relationship between gut microbiota and prostate cancer contributes to the gut-prostate axis: insights from a Mendelian randomization study

Li Wang, Yong-bo Zheng, Shan Yin, Kun-peng Li, Jia-hao Wang, Er-hao Bao, Ping-yu Zhu

The prevalence of ADSL (rs3788579) and CYP1A2 (rs17861162) polymorphisms in female breast cancer patients in North-West Iran

Mohammad Valizadeh Osalo, Parisa Hosseini, Hamed Charkhian, Hossien Soltanzadeh, Selda Goharkhany, SEREF BUGRA TUNCER

Low serum total cholesterol levels predict inferior prognosis of patients with POEMS syndrome

Jue Zhang, Ting Zhang, Ye Yao, Xuxing Shen, Yuanyuan Jin, Run Zhang, Lijuan Chen

Unveiling NUSAP1 as a common gene signature linking chronic HBV infection and HBV-related HCC

Jiao Meng, Zhenkun Yang, Xinyi Jiang, Jian Zou

The impact of radiomics in the management of soft tissue sarcoma

Riccardo De Angelis, Roberto Casale, Nicolas Coquelet, Samia Ikhlef, Ayoub Mokhtari, Paolo Simoni, Maria Antonietta Bali

Identification and validation of a novel six-gene signature based on mucinous adenocarcinoma-related gene molecular typing in colorectal cancer

Yuxin Man, Dao Xin, Yang Ji, Yang Liu, Lingna Kou, Lingxi Jiang

Clinical experience of consolidative radiotherapy for localized metastatic non-small cell lung cancer who showed favorable tumor response after systemic treatment

Hakyoung Kim, Sun Myung Kim, Jeongeun Hwang, Dae Sik Yang

LncRNA XIST promotes bladder cancer progression by modulating miR-129-5p/TNFSF10 axis

Yu-Lin Kong, Hui-Dan Wang, Meng Gao, Sheng-Zhong Rong, Xiao-Xia Li

  • Open Access
  • Research

SAA1 regulated by S1P/S1PR1 promotes the progression of ESCC via β-catenin activation

Qianqian Li, Maolin Tang, Shisheng Zhao, Junjie Yang, Yuanlin Meng, Chunmei Meng, Ling Ren, Weimin Hu

  • Open Access
  • NSCLC
  • Research

Identification of gene variation feature for targeted therapy of non-small cell lung cancer through combined method of DNA and RNA sequencing

Wenguang Pang, Longlong Gong, Wangpan Shi, Hongbo Zheng, Min Ye, Jiarong Chen, Ronggang Li, Xin Zhang, Dong Ren, Zheng Wang

Transarterial chemoembolization with/without immune checkpoint inhibitors plus tyrosine kinase inhibitors for unresectable hepatocellular carcinoma: a single center, propensity score matching real-world study

Guosheng Yuan, Wenli Li, Mengya Zang, Rong Li, Qi Li, Xiaoyun Hu, Qi Zhang, Wei Huang, Jian Ruan, Huajin Pang, Jinzhang Chen

DDOST is associated with tumor immunosuppressive microenvironment in cervical cancer

Jie Mei, Liuliu Pan, Min Huang, Dandan Bao, Hui Gao, Danhan Wang

Transcriptome and single-cell transcriptomics reveal prognostic value and potential mechanism of anoikis in skin cutaneous melanoma

Xing Liu, Hong-Yan Zhang, Hong-Ao Deng

A programmed cell death-related gene signature to predict prognosis and therapeutic responses in liver hepatocellular carcinoma

Xinyu Gu, Jie Pan, Yanle Li, Liushun Feng

  • Open Access
  • NSCLC
  • Research

GABPB1 plays a cancer-promoting role in non-small cell lung cancer

Tuo Wang, Cong Cao, Yu Fan, Jialing Xu, Tao Hua, Jie Ding, Zejie Liu, Beili Wang, Juanwen Lian

GALNT2 targeted by miR-139-5p promotes proliferation of clear cell renal cell carcinoma via inhibition of LATS2 activation

Haisheng Yi, Lingyun Liu, Jingshun Zhang, Kaimin Guo, Yin Cao, Penghao Sun, Hongliang Wang

Role of long non-coding RNA ELFN1-AS1 in carcinogenesis

Zanyar HajiEsmailpoor, Alireza Fayazi, Mohammadhossein Teymouri, Peyman Tabnak

  • Open Access
  • Research

Identification of a disulfidptosis-related lncRNA signature for the prognostic and immune landscape prediction in head and neck squamous cell carcinoma

Zhengyu Wei, Chongchang Zhou, Yi Fang, Hongxia Deng, Zhisen Shen

Excluding external iliac node irradiation during neoadjuvant radiotherapy decreases lower intestinal toxicity without compromising efficacy in T4b rectal cancer patients with tumours involving the anterior structures

Anchuan Li, Miaobin Mao, Runfan Chen, Pan Chi, Ying Huang, Junxin Wu, Benhua Xu

Solid pseudopapillary neoplasm (SPN) of the pancreas: current understanding on its malignant potential and management

Xiaoyue Lu, Hao Chen, Taiping Zhang

Evaluation of next-generation sequencing versus next-generation flow cytometry for minimal-residual-disease detection in Chinese patients with multiple myeloma

Mo Zhou, Yan Chen, Yanlei Gong, Mingqing Zhu, Jiannong Cen, Jinlan Pan, Lingzhi Yan, Jingjing Shang, Song Jin, Xiaolan Shi, Weiqin Yao, Shuang Yan, Depei Wu, Suning Chen, Chengcheng Fu, Li Yao

Notch appearance as a novel radiological predictor of transient expansion and good outcome of expanding schwannoma after radiotherapy

Masahiro Yamazaki, Shigeyuki Takamatsu, Yuta Iwata, Takayuki Sakurai, Masashi Taka, Satoshi Kobayashi, Toshifumi Gabata, Eiichi Mizuno

Genetically driven predisposition leads to an unusually genomic unstable renal cell carcinoma

Manuel Scimeca, Valentina Rovella, Sabrina Caporali, Yufang Shi, Julia Bischof, Jonathan Woodsmith, Giuseppe Tisone, Giuseppe Sica, Ivano Amelio, Gerry Melino, Alessandro Mauriello, Pierluigi Bove

Effect of early peri-operative arterial lactate concentration level ratios on post-hepatectomy liver failure

Dong-Dong Wang, Meng-Meng Dong, Ya-Ming Xie, Fei-Qi Xu, Tian-Wei Fu, Yu-Chen Wu, Zhe Zhang, Yi Lu, Lei Liang, Wei-Feng Yao, Guo-Liang Shen, Jun-Wei Liu, Cheng-Wu Zhang, Qiu-Ran Xu, Zun-Qiang Xiao

FAM83D acts as an oncogene by regulating cell cycle progression via multiple pathways in synovial sarcoma: a potential novel downstream target oncogene of anlotinib

Zi-mei Liu, Ying Yuan, Lei Jin

Mechanism of regulation of KIF23 on endometrial cancer cell growth and apoptosis

Ruiying Zhuang, Haiyan Liu

  • Open Access
  • Research

Circular RNA circCHSY1 silencing inhibits the malignant progression of esophageal squamous cell carcinoma

Haiquan He, Ying Chen, Hanping Liang, Weibi Che, Huilong Chen, Ying Chen, Fengyuan Peng, Bomeng Wu

A prognostic model for overall survival in recurrent glioma patients treated with bevacizumab-containing therapy

Shanmu Jin, Wenlin Chen, Xiaopeng Guo, Hao Xing, Huiyu Yang, Qianshu Liu, Delin Liu, Kun Zhang, Hai Wang, Yu Xia, Siying Guo, Yaning Wang, Yixin Shi, Yilin Li, Yuekun Wang, Junlin Li, Jiaming Wu, Tingyu Liang, Tian Qu, Huanzhang Li, Tianrui Yang, Yu Wang, Wenbin Ma

Effect of Annexin A2 on prognosis and sensitivity to immune checkpoint plus tyrosine kinase inhibition in metastatic renal cell carcinoma

Jiajun Wang, Jinglai Lin, Jiahao Wang, Ying Wang, Yanjun Zhu, Xianglai Xu, Jianming Guo

Nephroblastoma-specific dysregulated gene SNHG15 with prognostic significance: scRNA-Seq with bulk RNA-Seq data and experimental validation

Mengmeng Chang, Ding Li, Li Su, Chen Ding, Zhiyi Lu, Hongjie Gao, Fengyin Sun

Circ_0020460 drives tumorigenesis in cervical cancer through miR-485-3p sponging

Kun Yan, Chunyan Hu, Yali Cheng, Lingzhi Zheng, Baojin Zeng, Sujun Zhao, Chen Liu

Repression of LSD1/KDM1A activity improves the response of liver cancer cells to the lenvatinib

Yi Zong, Zhigang Tao, Siyi Jiang, Minyuan Wang, Weihua Yu

High-throughput metabolomics identifies new biomarkers for cervical cancer

Xue Li, Liyi Zhang, Xuan Huang, Qi Peng, Shoutao Zhang, Jiangming Tang, Jing Wang, Dingqing Gui, Fanxin Zeng

The predictive value of NLR, PLR and MLR in the differential diagnosis of benign uterine diseases and endometrial malignant tumors

Lin Qin

Heterogeneous expression of ARID1A in colorectal cancer indicates distinguish immune landscape and efficacy of immunotherapy

Xin Guan, Luying Cui, Yuli Ruan, Lin Fang, Tianjiao Dang, Yanqiao Zhang, Chao Liu

Primary squamous cell carcinoma of the breast: a case report

Xibo Liu, Jiahui Chen, Chuanling Hou

Circulating tumor cells clusters and their role in Breast cancer metastasis; a review of literature

Zeinab S. Sayed, Mohamed G. Khattap, Mostafa A. Madkour, Noha S. Yasen, Hanan A. Elbary, Reem A. Elsayed, Dalia A. Abdelkawy, Al-Hassan Soliman Wadan, Islam Omar, Mohamed H. Nafady

Immunohistochemical and molecular profiles of heterogeneous components of metaplastic breast cancer: a squamous cell carcinomatous component was distinct from a spindle cell carcinomatous component

Takahiro Suzuki, Yoko Nakanishi, Tomoyuki Tanino, Haruna Nishimaki-Watanabe, Hiroko Kobayashi, Sumie Ohni, Xiaoyan Tang, Kenichi Hakamada, Shinobu Masuda

Cyclovirobuxine D inhibits hepatocellular carcinoma growth by inducing ferroptosis of hepatocellular carcinoma cells

Xinru Jiang, Hongdan Li, Yang Liu

  • Open Access
  • Research

The combined effect of MTHFR C677T and A1298C polymorphisms on the risk of digestive system cancer among a hypertensive population

Qiangqiang He, Yaping Wei, Hehao Zhu, Qiongyue Liang, Ping Chen, Shuqun Li, Yun Song, Lishun Liu, Binyan Wang, Xiping Xu, Yuhan Dong

  • Open Access
  • Research

BRD4 inhibitors broadly promote erastin-induced ferroptosis in different cell lines by targeting ROS and FSP1

Chenyang Fan, Xiaohong Guo, Jie Zhang, Wen Zheng, Chonglin Shi, Yongwei Qin, Haoliang Shen, Yang Lu, Yihui Fan, Yanli Li, Liuting Chen, Renfang Mao

  • Open Access
  • Review

MAP3K4 kinase action and dual role in cancer

Yuxin Huang, Guanwen Wang, Ningning Zhang, Xiaohua Zeng

Development of chitosan-folate modified PLGA nanoparticles for targeted delivery of diosgenin as an anticancer agent

Fatemeh Teymouri, Ehsan Karimi

  • Open Access
  • Research

Fibrin glue mediated direct delivery of radiation sensitizers results in enhanced efficacy of radiation treatment

Jane Nguyen, Akhil Chandekar, Sophia Laurel, Jazleen Dosanjh, Keya Gupta, Justin Le, Henry Hirschberg

Identification of immune-associated biomarker for predicting lung adenocarcinoma: bioinformatics analysis and experiment verification of PTK6

Ren-Hui Xiong, Shuo-Qi Yang, Ji-Wei Li, Xun-kai Shen, Lu-Ming Jin, Chao-Yang Chen, Yu-Ting Yue, Zhi-Chen Yu, Qing-Yu Sun, Wen Jiang, Ming-Zheng Jiang, Xiao-Yan Wang, Shi-Xu Song, Dai Cao, Hong-li Ye, Li-Ran Zhao, Li-Peng Huang, Liang Bu

Giant cell tumor of bone at distal radius suffered more soft tissue recurrence and ultrasonography is effective to detect the soft tissue recurrence

Lukuan Cui, Yang Sun, Tao Jin, Daoyang Fan, Weifeng Liu

Outcomes of thyroidectomy for secondary thyroid malignancies, a single center experience

Yunushan Furkan Aydoğdu, Emre Gülçek, Çağrı Büyükkasap, Hasan Bostancı

Efficacy and safety of lenalidomide in the treatment of B-cell non-Hodgkin lymphoma

Yang Liu, Yanju Li, Chike Zhang, Xu Yang, Bo Yang, Jinyang Cheng, Juan Chen, Xiaoshuang Yuan, Ya Li, Ying Chen, Fengqi Zhang, Dongxin Tang, Zhixu He, Feiqing Wang

Morbidity and mortality of patients with peritoneal malignancy following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

Greta Hotza, Michael Karageorgos, Varvara Pastourmatzi, Nader Baniowda, Dimitrios Kyziridis, Apostolos Kalakonas, Nicolaos Chavouzis, Irene Hotza, Antonios-Apostolos Tentes

  • Open Access
  • Review

Relationship of mTORC1 and ferroptosis in tumors

Huilin Liao, Yueqing Wang, Lili Zou, Yanmei Fan, Xinyue Wang, Xiancong Tu, Qiaobai Zhu, Jun Wang, Xiaowen Liu, Chuanjiang Dong

Significance and implications of FHIT gene expression and promoter hypermethylation in acute lymphoblastic leukemia (ALL)

Fozia Mohammad, Arshad A. Pandith, Shayaq Ul Abeer Rasool, Faisal R. Guru, Iqbal Qasim, Sajad Geelani, Syed Nisar, Shahid M. Baba, Farooq A. Ganie, Safiya Kouser, Javid Rasool

L-cysteine contributes to destructive activities of odontogenic cysts/tumor

Ji Li, Chunyu Feng, Xiaochan Pang, Xiang Li, Xinyu Dou, Erhui Jiang, Zhengjun Shang

Hypoxic microenvironment-induced exosomes confer temozolomide resistance in glioma through transfer of pyruvate kinase M2

Guofu Li, Ziyu Xiong, Ying Li, Cong Yan, Yingying Cheng, Yuwen Wang, Jingwei Li, Zifeng Dai, Dongdong Zhang, Wenzhong Du, Chunyang Men, Changbin Shi

Advances in tumor microenvironment and underlying molecular mechanisms of bladder cancer: a systematic review

Liu Tang, Haifei Xu, Tong Wu, Wenhao Wu, Yuhao Lu, Jijia Gu, Xiaoling Wang, Mei Zhou, Qiuyang Chen, Xuan Sun, Hongzhou Cai

  • Open Access
  • Research

Integrating iron metabolism-related gene signature to evaluate prognosis and immune infiltration in nasopharyngeal carcinoma

Jiaming Su, Guanlin Zhong, Weiling Qin, Lu Zhou, Jiemei Ye, Yinxing Ye, Chang Chen, Pan Liang, Weilin Zhao, Xue Xiao, Wensheng Wen, Wenqi Luo, Xiaoying Zhou, Zhe Zhang, Yonglin Cai, Cheng Li

DSCAM-AS1 promotes the development of prostate cancer

Lin Cheng, Shuhui Li, Deqi Jiang, Jianchao Zhang

Diagnostic value of circulating tumor cells in patients with thyroid cancer: a retrospective study of 1478 patients

Qingxin Zeng, Haifeng Zhong, Hui Rao, Yuedong Wang

Bilateral adrenal neuroblastoma: peculiar pattern of a rare pediatric presentation

Mohamed Fawzy, Gehad Ahmed, Yasser Youssef, Naglaa Elkinaai, Amal Refaat, Mai Amr Elahmadawy, Fadwa Said, Salma Elmenawi

A combination of cuproptosis and lncRNAs predicts the prognosis and tumor immune microenvironment in cervical cancer

Yitong Huang, Chenxiang Pan, Suni Wu, Feng Ye, Lihua Yang

Identification of hub genes and diagnostic efficacy for triple-negative breast cancer through WGCNA and Mendelian randomization

Yilong Lin, Songsong Wang, Qingmo Yang

Application value of intraoperative electrophysiological monitoring in cerebral eloquent area glioma surgery: a retrospective cohort study

Yuankun Liu, Songyun Zhao, Jin Huang, Pengpeng Zhang, Qi Wang, Zhuwen Chen, Lingjie Zhu, Wei Ji, Chao Cheng

Immune-related LncRNAs scores predicts chemotherapeutic responses and prognosis in cervical cancer patients

Weijie Tian, Songsong Tan, Jun Wang, Ping Shen, Qingfen Qin, Dan Zi

  • Open Access
  • Research

Circular RNA COL1A1 promotes Warburg effect and tumor growth in nasopharyngeal carcinoma

ZeJun Zhou, Fang Xu, Tao Zhang

T cell-mediated tumor killing sensitivity gene signature-based prognostic score for acute myeloid leukemia

Yiyun Pan, FangFang Xie, Wen Zeng, Hailong Chen, Zhengcong Chen, Dechang Xu, Yijian Chen

Prediction of prostate cancer aggressiveness using magnetic resonance imaging radiomics: a dual-center study

Nini Pan, Liuyan Shi, Diliang He, Jianxin Zhao, Lianqiu Xiong, Lili Ma, Jing Li, Kai Ai, Lianping Zhao, Gang Huang

The clinical significance and oncogenic function of LRRFIP1 in pancreatic cancer

Jinping Li, Dayun Tuo, Gunan Guo, Yan Gao, Jinfeng Gan

SLC35A2 expression is associated with HER2 expression in breast cancer

Yiran Wang, Xiaobo Peng, Meihong Wu, Bin Wang, Tianran Chen, Xianbao Zhan

HBO regulates the Warburg effect of hypoxic HCC cells through miR-103a-3p/TRIM35

Yuting Ding, Wenkang Luan, Zhe Wang, Bo Xie, Chengfa Sun

Comparison of clinicopathological and prognostic features of breast cancer patients younger than 40 years and older than 65 years

Yaşar Culha, Sena Ece Davarci, Beyza Ünlü, Duygu Özaşkin, Hacer Demir, Meltem Baykara

Survival among treated tongue cancer patients: a single-center experience

Pablo Veiga-San Roman, Victor Villanueva San Vicente, M. Angeles Rodriguez-Gonzalez, Pia López-Jornet

An endothelial-related prognostic index for bladder cancer patients

Deng-xiong Li, Rui-cheng Wu, Jie Wang, Qing-xin Yu, Zhou-ting Tuo, Lu-xia Ye, De-chao Feng, Shi Deng

Case report: Mutation evolution in a patient with TdT positive high grade B cell lymphoma with MYC and BCL2 rearrangements following the treatment of concurrent follicular lymphoma and diffuse large B-cell lymphoma

Fen Zhang, Yu Chen, Qian Cui, Yan Ge, Yanhui Liu

Comprehensive analysis and prognostic assessment of senescence-associated genes in bladder cancer

Ruilin Yang, Jieling He, Wenfeng Luo, Renyang Xiang, Ge Zou, Xintao Zhang, Huang Liu, Junhong Deng

Identification and validation of diagnostic and prognostic biomarkers in prostate cancer based on WGCNA

Xi Xiao, Liangliang Qing, Zonglin Li, Fuxiang Ye, Yajia Dong, Jun Mi, Junqiang Tian

AKR1B10 accelerates glycolysis through binding HK2 to promote the malignant progression of oral squamous cell carcinoma

Ye Cai, Huiling Li, Diya Xie, Yanan Zhu

Stratification and prognostic evaluation of breast cancer subtypes defined by obesity-associated genes

Dongjuan Chen, Zilu Xie, Jun Yang, Ting Zhang, Qiliang Xiong, Chen Yi, Shaofeng Jiang

Anlotinib inhibits growth of human esophageal cancer TE-1 cells by negative regulating PI3K/Akt signaling pathway

Yueli Liu, Fan Li, Qiongyu Wang, Yunfei Zhang, Shuhong Tian, Biao Li

  • Open Access
  • Research

Overexpression of SYNGAP1 suppresses the proliferation of rectal adenocarcinoma via Wnt/β-Catenin signaling pathway

Yun Xiao, Ying Zhu, Jiaojiao Chen, Mei Wu, Lan Wang, Li Su, Fei Feng, Yanli Hou

  • Open Access
  • Review

The application of plant-exosome-like nanovesicles as improved drug delivery systems for cancer vaccines

Tatiana Hillman

  • Open Access
  • Analysis

The S100 family is a prognostic biomarker and correlated with immune cell infiltration in pan-cancer

Xiaojie Liang, Xiaoshan Huang, Zihong Cai, Yeling Deng, Dan Liu, Jiayi Hu, Zhihao Jin, Xinyu Zhou, Hongsheng Zhou, Liang Wang

Drug resistance in breast cancer is based on the mechanism of exocrine non-coding RNA

Simin Ye, Shiyu Chen, Xiaoyan Yang, Xiaoyong Lei

Pan-cancer analysis of prognostic and immunological role of IL4I1 in human tumors: a bulk omics research and single cell sequencing validation

Bin Chen, Yi Liu, Yuping He, Chenfu Shen

Identification of a pyroptosis-immune-related lncRNA signature for prognostic and immune landscape prediction in bladder cancer patients

Fuguang Zhao, Zhibo Jia, Hui Xie

A cuproptosis-related signature predicts prognosis and indicates cross-talk with immunocyte in ovarian cancer

Bikang Yang, Juan Yang, Keqiang Zhang

  • Open Access
  • NSCLC
  • Research

Longitudinal tracking of circulating rare events in the liquid biopsy of stage III–IV non-small cell lung cancer patients

Lily Bai, George Courcoubetis, Jeremy Mason, James B. Hicks, Jorge Nieva, Peter Kuhn, Stephanie N. Shishido

circ_WASF2 regulates ferroptosis by miR-634/ GPX4 signaling in pancreatic cancer

Tao Liu, Xing-ming Xie, Ya-peng He, Jia-yao Zhang, Jun-ying Mou

The regulation of hypoxia-related lncRNAs in hepatocellular carcinoma

Xuejing Wang, Xiaojun Wang

  • Open Access
  • Research

Crosstalk between cancer cells and macrophages promotes OSCC cell migration and invasion through a CXCL1/EGF positive feedback loop

Wei Huang, Mingjing Jiang, Ying Lin, Ying Qi, Bo Li

miRNA-200c-3p deficiency promotes epithelial-mesenchymal transition in triple-negative breast cancer by activating CRKL expression

Fangfang Nie, Qinfang Zhang, WeiNa Ma, Jun Yan

Nomogram for predicting survival in T1–T2 stage patients with supraglottic squamous cell carcinoma

Mulading Maimaitituerxun, Paiheriding Kamilijiang, Aierpati Maimaiti, Yalikun Yasheng, Jun Yong, Ayiheng Qukuerhan, Muredili Mutalifu, Pilidong Kuyaxi, Muzhapaier Mierzhakemu, Aierpati Aierken, Jiulalai Jueraiti, Nilipaer Alimu

CXCL10 could be a prognostic and immunological biomarker in bladder cancer

Tao Yin, Shuanzhu Mou, Haiyu Zhang, Ying Dong, Bing Yan, Weisheng Huang, Yuhan Liu, Hongbing Mei

Pan-cancer analysis for the prognostic and immunological role of CD47: interact with TNFRSF9 inducing CD8 + T cell exhaustion

Hongxin Liang, Yong Zheng, Zekai Huang, Jinchi Dai, Lintong Yao, Daipeng Xie, Duo Chen, Hongrui Qiu, Huili Wang, Hao Li, Jinhang Leng, Ziming Tang, Dongkun Zhang, Haiyu Zhou

  • Open Access
  • Research

Mechanism study of lncRNA RMRP regulating esophageal squamous cell carcinoma through miR-580-3p/ATP13A3 axis

ZiRui Tan, ShengJie Luan, XiaoPeng Wang, WenPeng Jiao, Pu Jiang

  • Open Access
  • Shock
  • Review

Hsp90α and cell death in cancers: a review

Bin Liu, Daohai Qian

Exploration of the influence of GOLGA8B on prostate cancer progression and the resistance of castration-resistant prostate cancer to cabazitaxel

Haopeng Li, Xin’an Wang, Menghe Zhai, Chengdang Xu, Xi Chen

Elucidating the impact of parthanatos-related microRNAs on the tumoral immune microenvironment and clinical outcome in low-grade gliomas

Penglei Zhu, Hao Wu, Buyi Zheng, Hua Wang, Yi Zou

Preclinical efficacy of CBR-5884 against epithelial ovarian cancer cells by targeting the serine synthesis pathway

Kunxiang Gong, Yinger Huang, Yanqin Zheng, Yinfu Zhu, Wenbo Hao, Kun Shi

Identification of NINJ1 as a novel prognostic predictor for retroperitoneal liposarcoma

Yu Zhao, Da Qin, Xiangji Li, Tiange Wang, Tong Zhang, Xiaosong Rao, Li Min, Zhiyi Wan, Chenghua Luo, Mengmeng Xiao

Elevated histone deacetylase 10 expression promotes the progression of clear cell renal cell carcinoma by Notch-1-PTEN signaling axis

Bin Zheng, Xue Jiang, Yaqing Liu, Fajuan Cheng, Yiming Zhang, Chengtao Niu, Zixiang Cong, Zhihong Niu, Wei He

  • Open Access
  • NSCLC
  • Research

circPDK1 competitively binds miR-4731-5p to mediate GIGYF1 expression and increase paclitaxel sensitivity in non-small cell lung cancer

YunYin Feng, TaoLong Zhang, Hong Liu

ZNF692 promotes the migration and response to immunotherapy of clear cell renal cell carcinoma cells by targeting metabolic pathway

Yuming Liu, Dehua Zeng, Yunzhen Gao

Molecular mechanism of MLCK1 inducing 5-Fu resistance in colorectal cancer cells through activation of TNFR2/NF-κB pathway

Huifen Tang, Hui Zhou, Liang Zhang, Tingting Tang, Ning Li

Prognostic significance and immune landscape of a cell cycle progression-related risk model in bladder cancer

Zhouting Tuo, Yuan Lin, Ying Zhang, Liang Gao, Dexin Yu, Jiani Wang, Chenyu Sun, Xianchao Sun, Jinyou Wang, Apurwa Prasad, Nimarta Bheesham, Muzi Meng, Zhengmei Lv, Xin Chen

Clinical research progress of callisperes® of drug-loaded microsphere arterial chemoembolisation in the treatment of solid tumors

Qin Wang, Lujian Zhu, Qiyue Sheng

Harnessing exosomes in theranostic applications: advancements and insights in gastrointestinal cancer research

Ali Shojaeian, S. R. Naeimi Torshizi, Mahsa Sadat Parsapasand, Zahra Sobhi Amjad, Ali Khezrian, Abbas Alibakhshi, Faye Yun, Kaveh Baghaei, Razieh Amini, Stevan Pecic

A ferroptosis-related signature predicts the clinical diagnosis and prognosis, and associates with the immune microenvironment of lung cancer

Hua Zhou, Xiaoting Zhou, Runying Zhu, Zhongquan Zhao, Kang Yang, Zhenghai Shen, Hongwen Sun

Interventional therapy combined with tyrosine kinase inhibitors with or without immune checkpoint inhibitors as initial treatment for hepatocellular carcinoma with portal vein tumor thrombosis: a systematic review and meta-analysis

Changjie Du, Hongyu Wu, Tao Zhong, Qilong Zhai, Jiajun Yuan, Jialun Peng, Rong Ma, Jinzheng Li

circ_0006789 promotes cervical cancer development via the miR-615-5p/HSF1 axis

Wenyu Zhou, Weiwei Song, Meisong Lu

  • Open Access
  • Review

Novel insights into the roles of migrasome in cancer

Sijun Deng, Yiwen Wu, Sheng Huang, Xiaoyan Yang

Targeting neutrophil elastase is a promising direction for future cancer treatment

Wangqiang Jia, Yudong Mao, Qianwen Luo, Jiang Wu, Quanlin Guan

Effectiveness and safety of PD-1/PD-L1 inhibitors monotherapy in patients with endometrial cancer

Xiaoyan Wan, Jiezheng Huang, Liu Huang, Yibin Wang, Yiyuan Fu, Xiaolong Jin, Zheng Huang, Jian Xiong

Development and validation of a nomogram integrating marital status for 5-year overall survival of chondrosarcoma: a population-based study

Chengxin Xie, Ruiyuan Jiang, Chenglong Wang, Xinhuan Lei, Kaicheng Lu, Hua Luo

Interleukin-12 in multimodal tumor therapies for induction of anti-tumor immunity

Yulian Xu, Xueli Sun, Yunguang Tong

Effect of American genomic ancestry on severe toxicities in children with acute lymphoblastic leukemia in the Amazon region

Alayde Vieira Wanderley, Francisco Cezar Aquino de Moraes, Giovanna Gilioli da Costa Nunes, Esdras Edgar Batista Pereira, Luciana Pereira Colares Leitão, Marcelo Braga de Oliveira, Ágatha Tereza Miranda Tavares, Laudreisa da Costa Pantoja, Bruna Cláudia Meireles Khayat, Marianne Rodrigues Fernandes, Paulo Pimentel de Assumpção, Ândrea Kely Ribeiro dos Santos, Rommel Mario Rodríguez Burbano, Sidney Emanuel Batista dos Santos, Raul Ribeiro, André Salim Khayat, Ney Pereira Carneiro dos Santos

Artificial intelligence assisted diagnosis of early tc markers and its application

Laney Zhang, Chinting Wong, Yungeng Li, Tianyi Huang, Jiawen Wang, Chenghe Lin

  • Open Access
  • Review

Polyamines: the pivotal amines in influencing the tumor microenvironment

Cassandra E. Holbert, Robert A. Casero Jr., Tracy Murray Stewart

Inflammatory myofibroblastic tumor of the liver after adrenal neuroblastoma surgery: a case report

Qiyang Shen, Xingyu Liu, Lijie Zhang, Tao Li, Jianfeng Zhou

MiR-6839-5p inhibits cell proliferation, migration and invasion; a possible correlation with the suppressing VEGFA expression in human chondrosarcoma cells

Fusheng Li, Jia Xu, Yue Zhu

Highly expressed of BID indicates poor prognosis and mediates different tumor microenvironment characteristics in clear cell renal cell carcinoma

Jiayi Zeng, Chuangbo Ke, Kaiwen Tian, Jianru Nie, Shaoming Huang, Xiaosong Song, Zhiyong Xian

  • Open Access
  • Research

Strobilurin X acts as an anticancer drug by inhibiting protein synthesis and suppressing mitochondrial respiratory chain activity

Kenji Takahashi, Tomoya Tanaka, Atsushi Ishihara, Toshio Ohta

Celastrol inhibits mouse B16-F10 melanoma cell survival by regulating the PI3K/AKT/mTOR signaling pathway and repressing HIF-1α expression

Ping Zhao, Xing-Bo He, Xin-Yue Chen, Zhang-Long Li, Wen-Jia Xing, Wei Liu, Cong Ren, Xu-Dong Han, Bin Guo

A novel conditional survival nomogram for monitoring real-time prognosis of non-metastatic colorectal cancer

Pei Luo, Ying-ying Li, Can Huang, Jun Guo, Xin Yao

Semi-supervised skin cancer diagnosis based on self-feedback threshold focal learning

Weicheng Yuan, Zeyu Du, Shuo Han

Extracellular vesicle-mediated drug delivery in breast cancer theranostics

Toufik Abdul-Rahman, Poulami Roy, Ranferi Eduardo Herrera-Calderón, Feriha Fatima Khidri, Quadri Ajibola Omotesho, Tolulope Sharon Rumide, Mahek Fatima, Sakshi Roy, Andrew Awuah Wireko, Oday Atallah, Subham Roy, Felix Amekpor, Shankhaneel Ghosh, Isaac Aksavdwa Agyigra, Viktoriia Horbas, Tetiana Teslyk, Valentyna Bumeister, Marios Papadakis, Athanasios Alexiou

GAS5 regulated by FTO-mediated m6A modification suppresses cell proliferation via the IGF2BP2/QKI axis in breast cancer

Yuzhao Yan, Jing Ma, Qingqiu Chen, Ting Zhang, Rui Fan, Junze Du

Molecular characterization, clinical value, and cancer–immune interactions of genes related to disulfidptosis and ferroptosis in colorectal cancer

Xianqiang Liu, Dingchang Li, Wenxing Gao, Peng Chen, Hao Liu, Yingjie Zhao, Wen Zhao, Guanglong Dong

Advances in the molecular regulation mechanism of tumor dormancy and its therapeutic strategy

Yuan Wang, Linlin Wang, Yaojun Wei, Chuang Wei, Haohang Yang, Qiurui Chen, Rongxin Zhang, Han Shen

A new prognostic model based on gamma-delta T cells for predicting the risk and aiding in the treatment of clear cell renal cell carcinoma

Yaqian Wu, Mengfei Yao, Zonglong Wu, Lulin Ma, Cheng Liu

CEACAM6 expression and function in tumor biology: a comprehensive review

Dong Zhao, Fei Cai, Xuefei Liu, Tingting Li, Ershu Zhao, Xinlong Wang, Zhendong Zheng

Bioinformatics analysis and experimental validation of m6A and cuproptosis-related lncRNA NFE4 in clear cell renal cell carcinoma

Rui Feng, Haolin Li, Tong Meng, Mingtian Fei, Cheng Yang

Integrative analysis indicates the potential values of ANKRD53 in stomach adenocarcinoma

Chunjing Jin, Xu Lu, Minfeng Yang, Shiqiang Hou

Circulating micrornas as potential diagnostic biomarkers for cervical intraepithelial neoplasia and cervical cancer: a systematic review and meta-analysis

Yue Li, Longbiao Zhu, Chenjing Zhu, Yan Chen, Hui Yu, Hangju Zhu, Ping Yin, Mengyu Liu, Yang Li, Huixin Li, Zhen Gong, Hanzi Xu, Jing Han

miR-4429 inhibits ccRCC proliferation, migration, and invasion by directly targeting CD274

GuangYi Hong, YiKun Wu, ShiYu Huang, Yang Hu, Ying Zhang, CiCi Guo, Hua Shi, ShuXiong Xu

Interferon-induced transmembrane protein 2 is a prognostic marker in colorectal cancer and promotes its progression by activating the PI3K/AKT pathway

Yonggang Liu, Jiyun Liang, Xi Li, Junyong Huang, Jiangyuan Huang, Jiale Wang

Identification and validation of a prognostic signature based on six immune-related genes for colorectal cancer

Lifeng Zheng, Ziyu Xu, Wulou Zhang, Hao Lin, Yepeng Zhang, Shu Zhou, Zonghang Liu, Xi Gu

Protosappanin B enhances the chemosensitivity of 5-fluorouracil in colon adenocarcinoma by regulating the LINC00612/microRNA-590-3p/Golgi phosphoprotein 3 axis

Zhongshi Hong, Yachen Li, Mingliang Chen, Xiaojing Chen, Xian Deng, Yuze Wu, Chunxiao Wang, Chengzhi Qiu

Plasma exosomes contain protein biomarkers valuable for the diagnosis of lung cancer

Zhiqiang Liu, Hong Huang, Jing Ren, Tingting Song, Yinyun Ni, Shengqiang Mao, Ying Yang, Dan Liu, Huairong Tang

  • Open Access
  • NSCLC
  • Research

Shenqi Fuzheng injection hinders non-small cell lung cancer cell growth by regulating the Bax/Bcl-2 signaling pathway

Siqi Li, Tianyu Ma, Gege Li, Xu Cheng, Tao Wen, Yuxuan Wang, Hongtao Zhang, Zhidong Liu

  • Open Access
  • Research

Pan-cancer analysis combined with experiments predicts NNMT as a therapeutic target for human cancers

Hua Huang, Lianchun Su, Ruihao Zhang, Di Wu, Chen Ding, Chen Chen, Guangsheng Zhu, Peijun Cao, Xuanguang Li, Yongwen Li, Hongyu Liu, Jun Chen

Bestatin attenuates breast cancer stemness by targeting puromycin-sensitive aminopeptidase

Yan Ma, Xintong Yang, Pengge Pan, Jinyi Yang, Xiaojuan Wu, Danhan Wang, Hui Gao

Identification of the biological functions and chemo-therapeutic responses of ITGB superfamily in ovarian cancer

Jiawen Han, Lin Lyu

Effects of immune cells in mediating the relationship between gut microbiota and myelodysplastic syndrome: a bidirectional two-sample, two-step Mendelian randomization study

Zuxi Feng, Minjing Liao, Xuege Guo, Lijuan Li, Liansheng Zhang

A rare case report: multiple intrahepatic masses in a pediatric patient with citrin deficiency

Hui Lin, Hong Jiang, Qiang Chen, Xiang Pan, Mei Deng, Xiang-Ran Cai, Yuan-Zhi Lu, Yuan-Zong Song, Jun-Cheng Liu

The relationship between contrast-enhanced computed tomography radiomics features and mitosis karyorrhexis index in neuroblastoma

Xin Chen, Haoru Wang, Yuwei Xia, Feng Shi, Ling He, Enmei Liu

The potent potential of MFAP2 in prognosis and immunotherapy of triple-negative breast cancer

Jing Huang, Yuting Xu, Shengnan Qi, Qi Zheng, Can Cui, Lei Liu, Fan Liu

Predicting prostate adenocarcinoma patients’ survival and immune signature: a novel risk model based on telomere-related genes

Jiefang Zheng, Jiahui Chen, Hongxiao Li, Yuanchao Li, Weimin Dong, Xianhan Jiang

Identification and evaluation of a six-lncRNA prognostic signature for multiple myeloma

Lu Xu, Zhihao Xie, Huanlin Jiang, Erpeng Wang, Min Hu, Qianlei Huang, Xinbao Hao

Dynamic changes of SCGN expression imply different phases of clear cell renal cell carcinoma progression

Tuanjie Guo, Xuan Wang, Tao Wang, Jian Zhang, Yang Liu, Siteng Chen, Xu Wang, Xiaoqun Yang, Chaofu Wang, Xiang Wang

Role of lipid metabolism in hepatocellular carcinoma

Yulin Cheng, Jun He, Bin Zuo, Yang He

Deciphering the role of zinc homeostasis in the tumor microenvironment and prognosis of prostate cancer

Tao Guo, Jian Wang, Xiangyu Meng, Ye Wang, Yihaoyun Lou, Jianglei Ma, Shuang Xu, Xiangyu Ni, Zongming Jia, Lichen Jin, Chengyu Wang, Qingyang Chen, Peng Li, Yuhua Huang, Shancheng Ren

  • Open Access
  • Research

Characteristics of mast cell infiltration in lung adenocarcinoma and its impact on prognosis

Zijian Qiu, Guanchao Pang, Xia Xu, Jun Lin, Pingli Wang

N6-methyladenosine modification and post-translational modification of epithelial–mesenchymal transition in colorectal cancer

Yingnan Wang, Yufan Chen, Miaomiao Zhao

Real-world experience with venetoclax-based therapy for patients with myeloid sarcoma

Xinyi Jian, Jie Cha, Zhijuan Lin, Siting Xie, Yueting Huang, Yun Lin, Haijun Zhao, Bing Xu, Yiming Luo

Exploring the therapeutic mechanisms of Coptidis Rhizoma in gastric precancerous lesions: a network pharmacology approach

Xuxing Ye, Chao Yang, Hanzhi Xu, Qin He, Lin Sheng, Junmei Lin, Xiaobo Wang

Nomograms incorporating hsa_circ_0029325 highly expressed in exosomes of hepatocellular carcinoma predict the postoperative outcomes

Kun-Li Yin, Taiwei Sun, Yu-Xin Duan, Wen-Tao Ye, Ming Li, Rui Liao

Efficacy of immunotherapy in ARID1A-mutant solid tumors: a single-center retrospective study

Hai Zhou, Dantong Sun, Shanai Song, Yurong Niu, Yuming Zhang, Hongwei Lan, Jiali Cui, Houde Liu, Ning Liu, Helei Hou

  • Open Access
  • Review

Exploring the enigma: history, present, and future of long non-coding RNAs in cancer

Qais Ahmad Naseer, Abdul Malik, Fengyuan Zhang, Shengxia Chen

Anti-tumor effect of dandelion flavone on multiple myeloma cells and its mechanism

Hua Gui, Xiaohong Fan

Prognostic and immunological significance of metastasis-associated protein 3 in patients with thymic epithelial tumors

Jinping Li, Zhenyan Deng, Yu Liu, Jiamin Jin, Chichu Xie, Jinfeng Gan

Lycorine attenuated proliferation and induced apoptosis on imatinib-resistant K562 cell by inhibiting autophagy

Jun Bai, Zuxi Feng, Yaqiong Chen, Yanhong Li, Liansheng Zhang, Lijuan Li

The potential contribution of aberrant cathepsin K expression to gastric cancer pathogenesis

Zhijun Feng, Lina Gao, Yapeng Lu, Xiaodong He, Jianqin Xie

An update on the molecular mechanisms of ZFAS1 as a prognostic, diagnostic, or therapeutic biomarker in cancers

Mahdieh Mehrab Mohseni, Hedyeh Zamani, Mina Momeni, Zeinab Shirvani-Farsani

A comprehensive analysis of GAS2 family members identifies that GAS2L1 is a novel biomarker and promotes the proliferation of hepatocellular carcinoma

Ying-Ying Xu, Ru-Xue Bai, Qing-Rui Zhang, Shuang Zhang, Jun-Hai Zhang, Shi-Yu Du

Chemotherapy resistance in acute myeloid leukemia is associated with decreased anti-tumor immune response through MHC molecule and B7 family members

Jing Ge, Xiaoxuan Yin, Xin Sun, Liduo Kou, Xin Xue, Juan Ma

Insights into the prognostic value and immunological role of CD74 in pan-cancer

Zebiao Liu, Mingquan Chen, Wanhua Zheng, Shicheng Yuan, Wenli Zhao

Acute promyelocytic leukemia in children cancer hospital Egypt

Samah Semary, Mahmoud Hammad, Dina Yassin, Nahla El Sharkawy, Sonya Soliman, Sherine Salem, Emad Ezzat, Ahmed Mosa, Sonia Ahmed

Resection of intrahepatic cholangiocarcinoma in octogenarians: a single-center analysis

Clara A. Weigle, Oliver Beetz, Bengt A. Wiemann, Philipp Tessmer, Simon Störzer, Sebastian Cammann, Florian W. R. Vondran, Felix Oldhafer, Moritz Schmelzle, Nicolas Richter

Research on lncRNA CTBP1-DT as a potential therapeutic target to regulate cell function in colorectal cancer

Ruizhi Fan, Teng Xu, Yuting Kuang

Repurposing FDA-approved compounds to target JAK2 for colon cancer treatment

Bavya Chandrasekhar, Ravi Gor, Satish Ramalingam, Anuradha Thiagarajan, Honglae Sohn, Thirumurthy Madhavan

Exploring prognostic values of DNA ploidy, stroma-tumor fraction and nucleotyping in stage II colon cancer patients

Yutong Lou, Lujing Yang, Shaojun Xu, Luxin Tan, Yanhua Bai, Lin Wang, Tingting Sun, Lixin Zhou, Li Feng, Shenyi Lian, Aiwen Wu, Zhongwu Li

Cuproptosis-related DNA methylation signature predict prognosis and immune microenvironment in cutaneous melanoma

Liucun Zhu, Xudong Kang, Shuting Zhu, Yanna Wang, Wenna Guo, Rui Zhu

The role of minimal residual disease and serum free light chain ratio in the management of multiple myeloma

Long-Ying Zhu, Qi-Lei Hu, Liang Zhang, Zuo-Jie Li

  • Open Access
  • NSCLC
  • Research

Effect of exercise on postoperative recovery of patients with non-small cell lung cancer: a systematic review and meta-analysis

Mingyue Jiao, Hanping Liang, Mengge Zhang

PG I and PG II show unique value in diagnosing postoperative biochemical recurrence in patients with gastric cancer after total gastrectomy

Jiuru Zhang, Jiameng Liu, Liyang Dong, Xi Wang, Xueqian Mao, Yufei Mao, Chaoming Mao

Targeting IL-11R/EZH2 signaling axis as a therapeutic strategy for osteosarcoma lung metastases

Eswaran Devarajan, R. Eric Davis, Hannah C. Beird, Wei-Lien Wang, V. Behrana Jensen, Arumugam Jayakumar, Cheuk Hong Leung, Heather Y. Lin, Chia-Chin Wu, Stephanie A. Ihezie, Jen-Wei Tsai, P. Andrew Futreal, Valerae O. Lewis

DcR3-associated risk score: correlating better prognosis and enhanced predictive power in colorectal cancer

Ying Duan, Hangrong Fang, Juanhong Wang, Banlai Ruan, Juan Yang, Jie Liu, Siqi Gou, Yijie Li, Zhengyi Cheng

Asperuloside inhibits the activation of pancreatic cancer-associated fibroblasts via activating transcription factor 6

Ling-zhi Cao, Fan-hui Yang, Hao Zhang, Ai-min Jia, Su-ping Li, Hu-ling Wen

Establishment and validation of a novel CD8+ T cell-associated prognostic signature for predicting clinical outcomes and immunotherapy response in hepatocellular carcinoma via integrating single-cell RNA-seq and bulk RNA-seq

Caihao Qu, Xin Yan, Yujie Wei, Futian Tang, Yumin Li

Establishment and validation of a novel disulfidptosis-related immune checkpoint gene signature in clear cell renal cell carcinoma

Lihuan Du, Nan Zhang, Bohan Wang, Wei Cheng, Jiaming Wen

BOLERO-5: a phase II study of everolimus and exemestane combination in Chinese post-menopausal women with ER + /HER2- advanced breast cancer

Zhi-Ming Shao, Li Cai, Shusen Wang, Xichun Hu, Kunwei Shen, Haibo Wang, Huiping Li, Jifeng Feng, Qiang Liu, Jing Cheng, Xinhong Wu, Xiaojia Wang, Hongyuan Li, Ting Luo, Jinping Liu, Khalid Amin, Khemaies Slimane, Yongping Qiao, Yongmin Liu, Zhongsheng Tong

PARP1 bound to XRCC2 promotes tumor progression in colorectal cancer

Kaiwu Xu, Zhige Yu, Tailiang Lu, Wei Peng, Yongqiang Gong, Chaowu Chen

A novel mitochondrial-related lncRNA signature mediated prediction of overall survival, immune landscape, and the chemotherapeutic outcomes for bladder cancer patients

Hao Xiong, Cheng Lin, Xiang Huang, Hao Wang

Breast cancer stage and molecular subtype distribution: real-world insights from a regional oncological center in Hungary

Judit Tittmann, Tamás Ágh, Dalma Erdősi, Bettina Csanády, Erika Kövér, Antal Zemplényi, Sándor Kovács, Zoltán Vokó

Understanding the heterogeneity in liver hepatocellular carcinoma with a special focus on malignant cell through single-cell analysis

Mengmeng Bao, Anshi Wu

Diagnostic value of immune-related biomarker FAM83A in differentiating malignant from benign pleural effusion in lung adenocarcinoma

Hangfeng Liu, Jia Yao, Yulan Liu, Liping Wu, Zhiwei Tan, Jie Hu, Shigao Chen, Xiaolin Zhang, Shuanghua Cheng

miR-200a-3p promotes the malignancy of endometrial carcinoma through negative regulation of epithelial-mesenchymal transition

Ying Ma, Yiru Wang, Can Wang, Yan Wang, Jingshu Hu, Zexue Zhang, Tuo Dong, Xiuwei Chen

The tumor immune microenvironment and T-cell-related immunotherapies in colorectal cancer

Liu Chuang, Ju Qifeng, Yu Shaolei

  • Open Access
  • Analysis

The role of LOXL2 in tumor progression, immune response and cellular senescence: a comprehensive analysis

Chen Ye, Sihan Jiang, Tanlun Zeng, Shaohui He, Jinjin Cao, Jianru Xiao

Comprehensive bioinformatics analysis of integrator complex subunits: expression patterns, immune infiltration, and prognostic signature, validated through experimental approaches in hepatocellular carcinoma

Yifei Xu, Wenlian Liao, Ting Wang, Liwei Zhang, Hui Zhang

OTUD7B knockdown inhibits proliferation and autophagy through AKT/mTOR signaling pathway in human prostate cancer cell

Yae Ji Kim, Hui Ju Lee, Kyung Hyun Kim, Sung Pil Cho, Ju Young Jung

CSRP1 gene: a potential novel prognostic marker in acute myeloid leukemia with implications for immune response

Chunxia Zhao, Yulu Wang, Huan Wang, Amit Sharma, Yun Wu, Ingo G. H. Schmidt-Wolf, Zifeng Wang

Activation of lncRNA DANCR by H3K27 acetylation regulates proliferation of colorectal cancer cells

Yue Han, Ti-Dong Shan, Hai-Tao Huang, Ming-Quan Song, Li Chen, Qian Li

FUT11 expression in gastric cancer: its prognostic significance and role in immune regulation

Yanqing Huang, Xiaoying Yang, Mengda Wei, Xi Yang, Zhenmin Yuan, Junjie Huang, Junren Wei, Lei Tian

Identification of placenta-specific protein 1 (PLAC-1) expression on human PC-3 cell line-derived prostate cancer stem cells compared to the tumor parental cells

Pooya Farhangnia, Roya Ghods, Reza Falak, Amir-Hassan Zarnani, Ali-Akbar Delbandi

The value of 68Ga-PSMA PET/CT in the diagnosis of intracapsular prostate cancer with a poor prognosis

Yajing Wang, Jieping Song, Lulu Yang, Wencheng Li, Wei Wang, Aiqing Ji, Liwei Wang, Feng Wang

Pancreatic cancer cell- and cancer-associated fibroblast-derived exosomes in disease progression, metastasis, and therapy

Yijun Chen, Jörg Kleeff, Yoshiaki Sunami

Integrating molecular pathway with genome-wide association data for causality identification in breast cancer

Yan-Shuang Li, Hong-Chuan Jiang

TCBIR/CD320: a potential therapeutic target upregulated in endothelial cells and associated with immune cell infiltration in liver hepatocellular carcinoma

Shubin Zhang, Zhongyi Jiang, Pusen Wang, Weihao Jiang, Wei Ding, Lin Zhong

Integrated pan-cancer and scRNA-seq analyses identify a prognostic coagulation-related gene signature associated with tumor microenvironment in lower-grade glioma

Xuehuan Wen, Songjie Bai, Zuochun Fang, Weiguo Zhu

Preparation, optimization, and characterization of genistein-ginseng long-acting polymeric gel as a breast cancer treatment alternative

Samaa Abdullah, Shadab Md, Abeer A. Altamimi, Hadil Alahdal, Raisuddin Ali, Huda Mohammed Alkreathy, Shahid Karim

Prognostic value of oxidative phosphorylation-related genes in hepatocellular carcinoma

Luzheng Liu, Jiacheng Chen, Fei Ye, Fengran Chu, Chaoluan Rao, Yong Wang, Yanggang Yan, Jincai Wu

Small molecule tyrosine kinase inhibitors approved for systemic therapy of advanced hepatocellular carcinoma: recent advances and future perspectives

Jianzhong Liu, Shuai Xia, Baoyi Zhang, Dina Mostafa Mohammed, Xiangliang Yang, Yanhong Zhu, Xinnong Jiang

Bibliometric and visual analysis in the field of two-dimensions nano black phosphorus in cancer from 2015 to 2023

Jing’an Huang, Ling Zhang, Boren Li, Yuanchu Lian, Xiaoxin Lin, Zonghuai Li, Bo Zhang, Zhongwen Feng

Establishment of a nomogram to predict the overall survival of patients with collecting duct renal cell carcinoma

Weixing Jiang, Zuowei Zou, Li Wen

Characteristics of adult retroperitoneal lymphangioma: a single center Chinese cohort study of 15 cases

Jie Liu, Zhi-Han Zhong, Shu-Sen Zheng

  • Open Access
  • Analysis

Constructing diagnostic signature of serum microRNAs using machine learning for early pan-cancer detection

Yuyan Xu, Wei Liao, Huanwei Chen, Mingxin Pan

Lathyrol reduces the RCC invasion and incidence of EMT via affecting the expression of AR and SPHK2 in RCC mice

Shengyou Song, Lunwei Tai, Yuqi Xu, Junling Jiang, Lei Zhou, Junfeng Zhao

lncRNA FLJ20021 regulates CDK1-mediated PANoptosis in a ZBP1-dependent manner to increase the sensitivity of laryngeal cancer-resistant cells to cisplatin

Xiaoyan Yin, Haizhong Zhang, Jingmiao Wang, Yanrui Bian, Qiaojing Jia, Zhichao Yang, Chunguang Shan

The pathogenesis mechanism and potential clinical value of lncRNA in gliomas

Yuan Liu, Hui Yuan, JingJia Fan, Han Wang, HuiYu Xie, JunFeng Wan, XueYing Hu, Jie Zhou, Liang Liu

MicroRNA-513b-5p inhibits epithelial mesenchymal transition of colon cancer stem cells through IL-6/STAT3 signaling pathway

Zefeng Zhang, Weihong Sha

Long-term outcomes of CNS WHO grade 2 oligodendroglioma in adult patients: a single-institution experience

Yukyeng Byeon, Chaejin Lee, Juhee Jeon, Gung Ju Kim, Sangjoon Chong, Young-Hoon Kim, Young Hyun Cho, Seok Ho Hong, Chang-Ki Hong, Jeong Hoon Kim, Sang Woo Song

Chemotherapy’s effects on autophagy in the treatment of Hodgkin’s lymphoma: a scoping review

Roro Wahyudianingsih, Ardo Sanjaya, Timothy Jonathan, Emmy Hermiyanti Pranggono, Dimyati Achmad, Bethy Suryawathy Hernowo

Efficacy and safety of tislelizumab plus bacillus-calmette guérin with or without chemotherapy as a bladder-sparing treatment for high-risk non-muscle-invasive bladder urothelial cancer: a real-world study

Peng Wu, Wei Zhang, Wei Hu, Yitong Cao, Jia Wang, Lei Yu

A cellular senescence-related signature for predicting prognosis, immunotherapy response, and candidate drugs in patients treated with transarterial chemoembolization (TACE)

Ning He, Wenjing Zhao, Wenlong Tian, Ying Wu, Jian Xu, Yunyan Lu, Xudong Chen, Hui Zhao

S-allyl-cysteine triggers cytotoxic events in rat glioblastoma RG2 and C6 cells and improves the effect of temozolomide through the regulation of oxidative responses

Carolina Y. Reyes-Soto, Ricardo J. Ramírez-Carreto, Luz Belinda Ortíz-Alegría, Alejandro Silva-Palacios, Cecilia Zazueta, Sonia Galván-Arzate, Çimen Karasu, Isaac Túnez, Alexey A. Tinkov, Michael Aschner, Tessy López-Goerne, Anahí Chavarría, Abel Santamaría

Novel associations between MTDH gene polymorphisms and invasive ductal breast cancer: a case–control study

Yan Huang, Dan Dai, Li Zhu, Xianzhong Qi

  • Open Access
  • NSCLC
  • Research

Analysis of tumor abnormal protein expression and epidermal growth factor receptor mutation status in non-small cell lung cancer

Yuanjun Cheng, Bin Chen, Qianru Fang, Guohui Zang, Jie Yao

Investigation of prognostic values of immune infiltration and LGMN expression in the microenvironment of osteosarcoma

Hualiang Xu, Dawei Xu, Yinfeng Zheng, Huajun Wang, Aiguo Li, Xiaofei Zheng

Study of sex-biased differences in genomic profiles in East Asian hepatocellular carcinoma

Chung-Yu Huang, Kien-Thiam Tan, Shiu-Feng Huang, Yen-Jung Lu, Yeh-Han Wang, Shu-Jen Chen, Ka-Po Tse

  • Open Access
  • Analysis

Causal inference of the effect of blood proteome on the risk of head and neck cancer: two-sample Mendelian randomization

Zhen Wang, Jianhao Wu

  • Open Access
  • Analysis

An analysis of the role of GAB2 in pan-cancer from a multidimensional perspective

Yi Yin, Yong Li, Yaoyang Zhang, Qiucheng Jia, Huiming Tang, Jiming Chen, Rui Ji

MICAL1 promotes the proliferation in acute myeloid leukemia and is associated with clinical prognosis and immune infiltration

Yinsen Song, Zhenzhen Yang, Na Gao, Bojun Zhang

Mapping alternative splicing events in colorectal cancer

Yifeng Zheng, Guoqiang Zhong, Qiuyu Song, Haonan Zhang, Shanping Wang, Chuangzhen Lin, Chengcheng He, Mingsong Li

CD147 TagSNP is associated with the vulnerability to lung cancer in the Chinese population: a case–control study

Yuning Xie, Chu Huang, Xianlei Zhou, Hongjiao Wu, Ang Li, Xuemei Zhang

Therapeutic potential of Buddleja Polystachya Fresen (stem and leaves) extracts: antimicrobial and cytotoxic properties for ocular disease management

Ali Hendi Alghamdi, Asaad Khalid, Aimun A. E. Ahmed, Haidar Abdalgadir, Mahadi Bashir, Ashraf N. Abdalla, Sami S. Ashgar, Hamdi M. Alsaid, Magbool E. Oraiby

The regulatory mechanism of m6A modification in gastric cancer

Si Wu, Chunming Li, Hanghao Zhou, Ying Yang, Na Liang, Yue Fu, Qingqing Luo, YaLi Zhan

Construction and assessment of an angiogenesis-related gene signature for prognosis of head and neck squamous cell carcinoma

Kaiqin Wang, Ruizhe Zhang, Changya Li, Huarong Chen, Jiafeng Lu, Houyu Zhao, Xianlu Zhuo

  • Open Access
  • NSCLC
  • Research

Clinical and structural insights into the rare but oncogenic HER2-activating missense mutations in non-small cell lung cancer: a retrospective ATLAS cohort study

Guangjian Yang, Runze Liu, Pei Li, Yaning Yang, Yajie Wang, Huiqing Mao, Xiaoyong Tang

AURKB promotes immunogenicity and immune infiltration in clear cell renal cell carcinoma

Weihao Liu, Ying Liu, Shisheng Chen, Jialiang Hui, Shuhua He

Establishing an oxidative stress mitochondria-related prognostic model in hepatocellular carcinoma based on multi-omics characteristics and machine learning computational framework

Yitian Wei, Lujuan Ma, Qian Peng, Lin Lu

Association of residual ductal carcinoma in situ with breast cancer treatment outcomes after neoadjuvant chemotherapy according to hormone receptor status

Eunju Shin, Tae-Kyung Yoo, Jisun Kim, Il Yong Chung, Beom Seok Ko, Hee Jeong Kim, Jong Won Lee, Byung Ho Son, Sae Byul Lee

Application of CAR-T cell therapy targeting mesothelin in solid tumor treatment

Qiuhong Chen, Yang Sun, Hua Li

Identification of hub genes and potential molecular mechanisms in MSS/MSI classifier primary colorectal cancer based on multiple datasets

Xia Qiao, Duan Ma, Xu Zhang

Neutrophil extracellular traps-related lncRNAs prognostic signature for gastric cancer and immune infiltration: potential biomarkers for predicting overall survival and clinical therapy

Shuhan Yang, Jiahui Liang, Xin Wang, Yijun Qi, Shixin Chan, Yonghu Song, Xiaohan Pei, Zhiyao Ren

Investigating the effect of Fusobacterium nucleatum on the aggressive behavior of cancer-associated fibroblasts in colorectal cancer

Fatemeh Eskandari-Malayeri, Marzieh Rezeai, Tahmineh Narimani, Nafiseh Esmaeil, Mahdieh Azizi

  • Open Access
  • Research

The chemokine CCL14 is a potential biomarker associated with immune cell infiltration in lung adenocarcinoma

Bai-er Sun, Zai-xin Yuan, Meng-jiao Wang, Li-qin Xu, Jian Feng, Jing-jing Chen

Cellular and molecular events in colorectal cancer: biological mechanisms, cell death pathways, drug resistance and signalling network interactions

Lei Yan, Jia Shi, Jiazuo Zhu

The roles of FGFR3 and c-MYC in urothelial bladder cancer

Dereje E. Bogale

Angiogenesis related genes based prognostic model of glioma patients developed by multi-omics approach

Zhimin Liu, Hongjun Fan, XuKai Liu, Chao liu

Integrative analysis reveals the potential prognostic roles and immunological values of unc-5 netrin receptor A (UNC5A) in glioma

Wenbo Qian, Lei Zhang, Fenglin Zhang, Jingliang Ye, Zhiping Wan, Huairui Chen, Chun Luo

Ataxin-2: a powerful RNA-binding protein

Lulu Li, Meng Wang, Lai Huang, Xiaoli Zheng, Lina Wang, Hongming Miao

Autophagy-related biomarkers in hepatocellular carcinoma and their relationship with immune infiltration

Tingting Li, Lin Zhang

Characterization of cuproptosis signature in clear cell renal cell carcinoma by single cell and spatial transcriptome analysis

Xiaohong Zou, Xiaoqing Liu, Huiting Wang, Zhenhua Li, Chen Zhou

Characterize molecular signatures and establish a prognostic signature of gastric cancer by integrating single-cell RNA sequencing and bulk RNA sequencing

Zhiwei Wang, Zhiyan Weng, Luping Lin, Xianyi Wu, Wenju Liu, Yong Zhuang, Jinliang Jian, Changhua Zhuo

Advances in antitumour therapy with oncolytic herpes simplex virus combinations

Xuejiao Qi

Pembrolizumab monotherapy survival benefits in metastatic non-small-cell lung cancer: a systematic review of real-world data

Tomasz Macioch, Maciej Krzakowski, Klaudia Gołębiewska, Małgorzata Dobek, Natalia Warchałowska, Maciej Niewada

Combined use of niraparib enhanced the inhibitory effect of Anti-GD2 antibody on osteosarcoma cells

Chen Wenyao, Ma Shuai, Fan Yifeng, Li Xinzhi, Que Xiangyong

Construction and validation of the prognostic nomogram model for patients with diffuse-type gastric cancer based on the SEER database

Ting Huang, ChuiPing Chan, Heran Zhou, Keke Hu, Lu Wang, Zhifeng Ye

The potential of cancer stem cells for personalized risk assessment and therapeutic intervention in individuals with intrahepatic cholangiocarcinoma

Jian Zhang, Tao Cui, Jiaobang Xu, Peng Wang, Chongqing Lv, Guozheng Pan

Knowledge mapping of exosomes in prostate cancer from 2003 to 2022: a bibliometric analysis

Yingjie Li, Lin Ma, Hualin Chen, Zhaoheng Jin, Wenjie Yang, Yi Qiao, Zhigang Ji, Guanghua Liu

  • Open Access
  • Analysis

A circadian rhythm-related lncRNA signature correlates with prognosis and tumor immune microenvironment in head and neck squamous cell carcinoma

Hongyu Zheng, Qiuyue Li, Kai Yang

  • Open Access
  • Research

A novel cancer-associated fibroblast signature for kidney renal clear cell carcinoma via integrated analysis of single-cell and bulk RNA-sequencing

Ling Lu, Huaguo Feng, Guohua Dai, Shuangquan Liu, Yi Feng, Haoyang Tan, Xian Zhang, Guoqing Hong, Xing Lai

Apoptotic signaling pathways in bone metastatic lung cancer: a comprehensive analysis

Yi Zhang, Yi Zheng, Jiakai Zhang, Chaoyang Xu, Junlong Wu

Combination of BCL-2 inhibitors and immunotherapy: a promising therapeutic strategy for hematological malignancies

Xiaohuan Peng, Futian Tang, Yanhong Li, Jun Bai, Lijuan Li, Liansheng Zhang

Progress in reeducating tumor-associated macrophages in tumor microenvironment

Yiming Zhao, Qianyang Ni, Weijian Zhang, Suyang Yu

Molecular and clinical characterization of atypical central neurocytomas: implications for diagnosis and treatment strategies

Feixia Sun, Zuocheng Yang, Ronghua Kong, Song Han

  • Open Access
  • Research

Increased infiltration of M2-polarized tumour-associated macrophages is highly associated with advanced disease stage and high expression of PD-L1 in buccal mucosa carcinoma

Hao-Jia Sun, Zhui-Feng Zheng, Li-Jun Zhang, Le Fang, Hua Fu, Shao-Yang Chen, Rong-Xiu Feng, Xiao-Yang Liu, Qing-Nan Tang, Xue-Wen Liu

Establishment of nomogram to predict overall survival and cancer-specific survival of local tumor resection in patients with colorectal cancer liver metastasis with unresectable metastases: a large population-based analysis

Songlin Hou, Lifa Li, Huafang Hou, Tong Zhou, He Zhou

Machine learning-based integration develops a mitophagy-related lncRNA signature for predicting the progression of prostate cancer: a bioinformatic analysis

Caixia Dai, Xiangju Zeng, Xiuhong Zhang, Ziqi Liu, Shunhua Cheng

IL-22 activates the PI3K-AKT pathway to promote colorectal cancer cell proliferation and metastasis

Hong-xun Ruan, Xiao-ning Qin, Wei Huang, Lin Lin

Hypofractionated stereotactic radiotherapy for brain metastases in lung cancer patients: dose‒response effect and toxicity

Kaicheng Pan, Bing Wang, Xiao Xu, Jiafeng Liang, Yi Tang, Shenglin Ma, Bing Xia, Lucheng Zhu

CircSorbs1 regulates myocardial regeneration and reduces cancer therapy-related cardiovascular toxicity through the Mir-99/GATA4 pathway

Kang Huang, Denggao Huang, Qiang Li, Jiangting Zeng, Ting Qin, Jianghua Zhong, Zanrui Zhong, Shijuan Lu

Prognostic value of fibrinogen change value in adrenocortical carcinoma patients

Chengquan Ma, Bin Yang, Quanzong Mao

Discovering the effect of combination of celecoxib and sorafenib on hepatocellular carcinoma

Wang Gu, Dongyun Zeng, Chao Zhang

  • Open Access
  • Review

Decoding high mobility group A2 protein expression regulation and implications in human cancers

Farah Khazem, Almoutassem Billah Zetoune

Automated contouring of CTV and OARs in planning CT scans using novel hybrid convolution-transformer networks for prostate cancer radiotherapy

Najmeh Arjmandi, Shahrokh Nasseri, Mehdi Momennezhad, Alireza Mehdizadeh, Sare Hosseini, Shokoufeh Mohebbi, Amin Amiri Tehranizadeh, Zohreh Pishevar

CCL28 promotes progression of hepatocellular carcinoma through PDGFD-regulated MMP9 and VEGFA pathways

Youyi Liu, Xingyi Chen, Xiading Zhang, Jingrou Guo, Yifei Tang, Cheng Jin, Minchen Wu

  • Open Access
  • Research

Pan-cancer analysis of COL15A1: an immunological and prognostic biomarker

Lei Zhu, Qianheng Jiang, Jun Meng, Haichun Zhao, Jie Lin

LINC01370 suppresses hepatocellular carcinoma proliferation and metastasis by regulating the PI3K/AKT pathway

Fei Xiao, Zhuoyun Zhang, Luqian Li, Xiaojie He, Yufeng Chen

  • Open Access
  • SCLC
  • Review

Antibody–drug conjugates treatment of small cell lung cancer: advances in clinical research

Yuan Meng, Xuerui Wang, Jie Yang, Meiying Zhu, Minghui Yu, Longhui Li, Yangyueying Liang, Fanming Kong

  • Open Access
  • NSCLC
  • Research

Effect of physical activity on patients of NSCLC

Qi Min, Shao Xianru, Sun Gengyun

Antibody–drug conjugates for breast cancer: a bibliometric study and clinical trial analysis

Mengjie Xing, Zhiyi Li, Yuwan Cui, Minghua He, Yang Xing, Lei Yang, Ziling Liu, Linzhi Luo, Hong Wang, Rui Guo

Integrative analysis of ferroptosis-related genes reveals that ABHD12 is a novel prognostic biomarker and facilitates hepatocellular carcinoma tumorigenesis

Tiantao Mao, Maosong Zhang, Zupei Peng, Min Tang, Tianyu Li, Chengshu Liang

Exploring prognostic DNA methylation genes in bladder cancer: a comprehensive analysis

Jianzhong Zhang, Junyan Chen, Manrou Xu, Tong Zhu

Predictive role of oxidative stress-related genes in colon cancer: a retrospective cohort study based on The Cancer Genome Atlas

Yajie Wang, Lin Xiao, Yisheng Pan

DDX21 functions as a potential novel oncopromoter in pancreatic ductal adenocarcinoma: a comprehensive analysis of the DExD box family

Shaohan Wu, Xiaofang Sun, Ruheng Hua, Chundong Hu, Lei Qin

  • Open Access
  • Research

Environment-responsive dopamine nanoplatform for tumor synergistic therapy

Chunmin Deng, Hao Zhang, Li Song

Accuracy and influencing factors of Type B2 vessels in predicting the invasion depth of superficial esophageal squamous cell carcinoma under narrow-band imaging magnifying endoscopy

Xu Lin, Xiaolu Lin, Wei Liang, Wangyin Deng, Wenming Liu

Outcome of whole brain irradiation with a dose-escalated simultaneous-integrated boost in patients with multiple large and/or diffuse brain metastases: real live data and review of the literature

Linda Agolli, Luca Nicosia, Thomas Hilger, Gheorghe Iancu, Ann-Katrin Exeli, Bastian Eul, Tobias Struffert, Till Acker, Daniel Habermehl

Integrated analysis of disulfidoptosis-related genes identifies NRP1 as a novel biomarker promoting proliferation of gastric cancer via glutamine mediated energy metabolism

Qiuhua Li, Guofeng Shi, Yuebo Li, Ren Lu, Zhaozhe Liu

A metabolic reprogramming-related gene signature correlates with prognosis and proliferation of BLCA

Yaoxin Wu, Yi Luo, Tinghao Li

STC2 suppresses triple-negative breast cancer migration and invasion by inhibition on EMT and promotion on cell apoptosis

Ruiwen Lei, Chaoling Yao, Renfeng Huang, Wanming Wu, Linyang Ou, Chuansheng Yang

Hepatitis B virus infection and the risk of gynecologic cancers: a systematic review and meta-analysis

Lan Peng, Zhongyan Dou, Shuhui Yu, Xingrao Wu, Jinping Zhang, Zheng Li, Lan Zhang

Association between systemic lupus erythematosus and common female reproductive system malignancies

Cheng Sirong, Kun Zhang, Yinxia Yang, Yuxuan Zhong, Pengyu Sun, Wang Zanhong

Novel therapeutic agents in clinical trials: emerging approaches in cancer therapy

Deepak Chandra Joshi, Anurag Sharma, Sonima Prasad, Karishma Singh, Mayank Kumar, Kajal Sherawat, Hardeep Singh Tuli, Madhu Gupta

The role of the ALKBH5 RNA demethylase in invasive breast cancer

Corinne L. Woodcock, Mansour Alsaleem, Michael S. Toss, Jennifer Lothion-Roy, Anna E. Harris, Jennie N. Jeyapalan, Nataliya Blatt, Albert A. Rizvanov, Regina R. Miftakhova, Yousif A. Kariri, Srinivasan Madhusudan, Andrew R. Green, Catrin S. Rutland, Rupert G. Fray, Emad A. Rakha, Nigel P. Mongan

CTGF, FN1, IL-6, THBS1, and WISP1 genes and PI3K-Akt signaling pathway as prognostic and therapeutic targets in gastric cancer identified by gene network modeling

Farzane Khoshdel, Negar Mottaghi-Dastjerdi, Fateme Yazdani, Shirin Salehi, Abozar Ghorbani, Hamed Montazeri, Mohammad Soltany-Rezaee-Rad, Babak Goodarzy

Comprehensive analysis of paraspeckle-associated gene modules unveils prognostic signatures and immunological relevance in multi-cancers

Zhuoyang Fan, Bowen Yin, Xiaochen Chen, Guowei Yang, Wei Zhang, Xiaodan Ye, Hong Han, Ming Li, Minfeng Shu, Rong Liu

Trimethylamine N-oxide promotes the proliferation and migration of hepatocellular carcinoma cell through the MAPK pathway

Chunfang Zhou, Rina Basnet, Chenxiang Zhen, Shinan Ma, Xingrong Guo, Zhongxia Wang, Yahong Yuan

CTHRC1 modulates cell proliferation and invasion in hepatocellular carcinoma by DNA methylation

Xiangjun Sun, Ye Liu, Changdong Cheng, Haoyu Sun, Liqiang Tian

The interplay between metal ions and immune cells in glioma: pathways to immune escape

Jin-wei Li, Yi-ming Mao, Shi-liang Chen, Rui Ye, Yi-ran Fei, Yue Li, Shi-yuan Tong, Hong-wei Yang, Yi-bo He

The impact of diabetes, hypercholesterolemia, and low-density lipoprotein (LDL) on the survival of cervical cancer patients

Qian Qiu, Jian Rong Song, Xiang Qin Zheng, Hui Zheng, Huan Yi

The utilization of blood serum ATR-FTIR spectroscopy for the identification of gastric cancer

Nan Pang, Wanli Yang, Guizhe Yang, Chao Yang, Kuiyuan Tong, Ruihua Yu, Feng Jiang

Male hermaphroditism with rare malignant transformation of gonadal organs: a case report

Zhengyu He, Zhiyuan Li, Mei Chen

Utilizing Liquid–liquid phase separation-related lncRNAs to predict the prognosis and treatment response of PCa

Jiangping Qiu, Cong Lai, Zhihan Yuan, Jintao Hu, Jiang Wu, Cheng Liu, Kewei Xu

A novel M2-like tumor associated macrophages-related gene signature for predicting the prognosis and immunotherapy efficacy in gastric cancer

Xuezhi Li, Xiaodong Qu, Na Wang, Songbo Li, Xingyu Zhao, Kexin Lin, Yongquan Shi

  • Open Access
  • Research

TOX: a potential new immune checkpoint in cancers by pancancer analysis

Shengliang Qiu, Weiye Lin, Zhengyang Zhou, Qianran Hong, Shuangyu Chen, Jiayang Li, Fengyun Zhong, Qinfeng Zhou, Dawei Cui

  • Open Access
  • SCLC
  • Review

Immunotherapy for small cell lung cancer: the current state and future trajectories

Min Qiang, Hongyang Liu, Lei Yang, Hong Wang, Rui Guo

BRD4 expression and its regulatory interaction with miR-26a-3p, DLG5-AS1, and JMJD1C-AS1 lncRNAs in gastric cancer progression

Mahya Ahmadpour Youshanlui, Amirhossein Yari, Seyedeh Zahra Bahojb Mahdavi, Mohammad Amini, Behzad Baradaran, Ramin Ahangar, Omid Pourbagherian, Amir Ali Mokhtarzadeh

A comprehensive analysis of TRP-related gene signature, and immune infiltration in patients with colorectal cancer

Yicheng Liu, Xiaobing Yao, Wenjun Zhao, Jin Xu, Haiyan Zhang, Ting Huang, Chuang Wu, Jiajia Yang, Cheng Tang, Qianqian Ye, Weiye Hu, Qingming Wang

Pediatric cancer—pathology and microenvironment influence: a perspective into osteosarcoma and non-osteogenic mesenchymal malignant neoplasms

Consolato M. Sergi

  • Open Access
  • Research

Research trends of bone tumor treatment with 3D printing technology from 2013 to 2022: a bibliometric analysis

Jia-Hao Chu, Yang Zhang, Yi Jiang, Hai-Fan Wu, Wen-Yi Wang, Min Wang, Jia-Hui Zhang, Kun Yan, Xin-Miao Yao

Talin1 promotes HCC progression by regulating NRG1/PI3K/AKT pathway

Jialong liu, Yao Lu, Bowen Zheng, Deng Huang, Juxian Song, Baolin Wang, Shuguo Zheng

  • Open Access
  • Analysis

Multiomics and machine learning-based analysis of pancancer pseudouridine modifications

Jiheng Zhang, Lei Xu, Xiuwei Yan, Jiahe Hu, Xin Gao, Hongtao Zhao, Mo Geng, Nan Wang, Shaoshan Hu

Subtyping of gastric cancer based on basement membrane genes that stratifies the prognosis, immune infiltration and therapeutic response

Xin Tang, Yu Liu, Jiarong Zhao, Changfang Fu, Wulin Yang

Analysis of risk factors for liver metastasis in patients with gastric cancer and construction of prediction model: A multicenter study

Heng Yu, Hang Jiang, Xiaofeng Lu, Chunhua Bai, Peng Song, Feng Sun, Shichao Ai, Yi Yin, Qiongyuan Hu, Song Liu, Xin Chen, Junfeng Du, Xiaofei Shen, Wenxian Guan

  • Open Access
  • Research

A bibliometric analysis of radiation-induced brain injury: a research of the literature from 1998 to 2023

Jinxin Lan, Yifan Ren, Yuyang Liu, Ling Chen, Jialin Liu

Recent advances in early detection of nasopharyngeal carcinoma

Wen Jiang, Bohao Zheng, Hongquan Wei

  • Open Access
  • Research

Trends in research on nanomedicine in urologic cancer: a bibliometric and visualized analysis

Xiaopeng Lan, Mei Feng, Lili Chen, Luchen Zhang, Chao Han, Yizhen Wang, Jilu Zheng, Xiaoyan Wang, Chunlei Liu, Ranlu Liu

Autophagy regulates apoptosis of colorectal cancer cells based on signaling pathways

Yuwei Yan, Wenyan Yu, Min Guo, Naicheng Zhu, Xiudan Chen, Nanxin Li, Chen Zhong, Guojuan Wang

Establish TIIC signature score based the machine learning fusion in bladder cancer

Xiangju Zeng, Zhijie Lu, Caixia Dai, Hao Su, Ziqi Liu, Shunhua Cheng

The complex role of macrophages in pancreatic cancer tumor microenvironment: a review on cancer progression and potential therapeutic targets

Parsa Lorestani, Mohsen Dashti, Negar Nejati, Mohammad Amin Habibi, Mandana Askari, Behruz Robat-Jazi, Sajjad Ahmadpour, Soheil Tavakolpour

Momelotinib in myelofibrosis and beyond: a comprehensive review of therapeutic insights in hematologic malignancies

Parisa alsadat Dadkhah, Mohammad Amin Karimi, Mohammad Sadra Gholami Chahkand, Fatemeh Esmaeilpour Moallem, Mohammad Javad Emami Kazemabad, Eftekhar Azarm

The roles of exosomes in esophageal cancer

Shihong Sun, Yingjie Shao, Wendong Gu

A novel model based on lipid metabolism-related genes associated with immune microenvironment predicts metastasis of breast cancer

Fan Ji, Hongyan Qian, Zhouna Sun, Ying Yang, Minxin Shi, Hongmei Gu

Retroperitoneal infantile hemangioma: a case report and literature review

Peizhe Li, Shuang He, Yabing Wu, Yuewen Pang, Lianjun Yang, Jing Shi, Junyao Duan, Yongji Yan

Optimized workflow of EV enrichment from human plasma samples for downstream mass spectrometry analysis

Patrick Erwied, Yi Gu, Lena Simon, Martin Schneider, Dominic Helm, Maurice Stefan Michel, Philipp Nuhn, Katja Nitschke, Thomas Stefan Worst

Clinical characteristics and analysis of related factors associated with early death in newly diagnosed patients with acute promyelocytic leukemia

Anyou Wang, Zhen Zhang, Ting Zhu, Xin Liu, Qiaohong Duan

Establishment of a prognostic model for pancreatic cancer based on mitochondrial metabolism related genes

Qinwen Ba, Xiong Wang, Yanjun Lu

Value analysis of preoperative peripheral blood LMR in predicting prognosis of serous papillary ovarian adenocarcinoma

Lin Qin

Genomic landscape of early-stage prostate adenocarcinoma in Mexican patients: an exploratory study

Dennis Cerrato-Izaguirre, Jonathan González-Ruíz, José Diaz-Chavez, Andrea Ramírez, Anna Scavuzzo, Miguel A. Jimenez, Carlo Cortés-González, Jairo A. Rubio, María D. Pérez-Montiel, Claudia M. García-Cuellar, Luis A. Herrera, Yesennia Sánchez-Pérez, Felipe Vaca-Paniagua, Salim Barquet-Muñoz, David Cantu-de-Leon, Promita Bose, Diddier Prada

LncRNA MALAT-1 modulates EGFR-TKI resistance in lung adenocarcinoma cells by downregulating miR-125

Jie Luo, Qiaoya Ren, Xiaoxi Liu, Qian Zheng, Ling Yang, Mi Meng, Hu Ma, Sisi He

Decreased PANK1 expression in kidney renal clear cell carcinoma: impact on cell apoptosis, invasion, migration, and epithelial-mesenchymal transition

Xiang Liu, Song Gao, Ye-Min Qin, Wei-Li Zhang, Peng Li, Xiao-Yun Xiang

  • Open Access
  • NSCLC
  • Research

BCAM (basal cell adhesion molecule) protein expression in different tumor populations

Sneha Burela, Mengni He, Ioannis P. Trontzas, Niki Gavrielatou, Kurt A. Schalper, Solomon Langermann, Dallas B. Flies, David L. Rimm, Thazin N. Aung

An observational study on the efficacy of targeted therapy for pulmonary sarcomatoid carcinoma

Takeshi Tsuda, Tomomi Ichikawa, Masahiro Matsumoto, Isami Mizusihima, Kenji Azechi, Naoki Takata, Nozomu Murayama, Kana Hayashi, Takahiro Hirai, Zenta Seto, Kotaro Tokui, Yasuaki Masaki, Chihiro Taka, Seisuke Okazawa, Kenta Kambara, Shingo Imanishi, Hirokazu Taniguchi, Toshiro Miwa, Ryuji Hayashi, Shoko Matsui, Minehiko Inomata

Assessment of the efficacy and safety of anlotinib for the treatment of recurrent epithelial ovarian cancer

Ying He, Aili Zhai, Kaiyun Qin, Xin Zhou, Yu Yu, Zhengmao Zhang

A real-world study of active vitamin D as a prognostic marker in patients with sarcoma

Lingyun Zhang, Wei Li, Xiao Wang, Shan Yu, Rongyuan Zhuang, Yuhong Zhou

  • Open Access
  • Review

MicroRNA-98 as a novel diagnostic marker and therapeutic target in cancer patients

Iman Akhlaghipour, Meysam Moghbeli

Integrated multi-omics characterization of SMAD4 mutant colorectal cancer

Danyi Zhao, Yanjun Qu, Na Gao, Tao Wu

Association between common chronic pulmonary diseases and lung cancer: Mendelian randomization analysis

Wenbin Zhang, Xinnan Song, Tianjun Song, Dongyun Zeng

  • Open Access
  • NSCLC
  • Analysis

Construction and analysis of a lysosome-dependent cell death score-based prediction model for non-small cell lung cancer

Jiangping Fu, Yaohua Chen, Jie Li, Ming Tan, Rui Lin, Jiang Wang, Guirong Wu, Yao Rao, Fudao Wu, Youshu Gao, Maoshu Bai, Pingfei Wang, Fang Wu

Impact the impact of gut microbiota on gastric cancer via immune cells: a comprehensive Mendelian randomization study and mediation analysis

Chao Wang, Jia Wang, Wenxian Guan, Bojian Fei

  • Open Access
  • NSCLC
  • Research

Tislelizumab synergizes with surgery to augment the survival benefit in stage II-III non-small cell lung cancer

Xuhua Huang, Linhai Zhu, Jiacong Liu, Yanye Wang, Yiqing Wang, Pinghui Xia, Wang Lv, Jian Hu

Glutamine and leukemia research: progress and clinical prospects

Zexin Wang, Miao Liu, Qiang Yang

Exosomal misfolded proteins released by cancer stem cells: dual functions in balancing protein homeostasis and orchestrating tumor progression

Anuran Bhattacharya, Urmi Chatterji

  • Open Access
  • Research

Exploring the prognosis value, immune correlation, and drug responsiveness prediction of homeobox C6 (HOXC6) in lung adenocarcinoma

Mei Xin, Huajian Peng, Linbo Zhang

A nomogram to predict cancer-specific mortality in adult patients with malignant meningioma: a competing risk analysis

Hongfu Zhang, Jing Li, Xin Wan, Zhuoyi Liu

Identification of E3 ubiquitin ligase-associated prognostic genes and construction of a prediction model for uterine cervical cancer based on bioinformatics analysis

Zhengchao Yan, Jingwei Yu, Shuyuan Wang, Weibo Wen, Mengyuan Xin, Xiangdan Li

Causality between autoimmune diseases and breast cancer: a two-sample Mendelian randomization study in a European population

Hengheng Zhang, Guoshuang Shen, Ping Yang, Meijie Wu, Jinming Li, Zitao Li, Fuxing Zhao, Hongxia Liang, Mengting Da, Ronghua Wang, Chengrong Zhang, Jiuda Zhao, Yi Zhao

Differentiation between multifocal CNS lymphoma and glioblastoma based on MRI criteria

Sebastian Johannes Müller, Eya Khadhraoui, Hans Henkes, Marielle Ernst, Veit Rohde, Bawarjan Schatlo, Vesna Malinova

Hsa_circ_ROBO1 competes with miR-324-3p and upregulates NME1 to promote tumor metastasis in nasopharyngeal carcinoma

FenFeng Liang, Hai Zhao, GengChun Liu, MeiLing Huang, ZhengJia Peng

  • Open Access
  • Research

CD24 affects the immunosuppressive effect of tumor-infiltrating cells and tumor resistance in a variety of cancers

Chunmei Zhao, Ying Huang, Haotian Zhang, Huimin Liu

The effect of preoperative supplementary parenteral nutrition on nutrition and inflammation in gastric cancer patients

Xiaoyan Huang, Changxing Cui, Jing Wang, Dongchi Kong, Yuanqing Cui, Peng Huang, Xuelong Li

  • Open Access
  • Research

Hsa_circYARS interacts with miR-29a-3p to up-regulate IREB2 and promote laryngeal squamous cell carcinoma progression

Zizhao Guo, Yuxia Zhao, Naicai Guo, Meng Xu, Xiaolei Wang

Diversity in gut microbiota among colorectal cancer patients: findings from a case–control study conducted at a Tunisian University Hospital

Mariem Zrelli, Asma Ferjani, Mariem Nouira, Sirine Hammami, Nadine Ghithia, Leila Mouelhi, Radhouane Debbeche, Didier Raoult, Ilhem Boutiba Ben Boubaker

Diagnostic value and clinical significance of serum miR-4534 combined with transvaginal color Doppler ultrasound in cervical cancer

Xiyan Shao, Lu Bai, Jinlan Liang, Ming Li

Unraveling the role of bisphenol A in osteosarcoma biology: insights into prognosis and immune microenvironment modulation

Liao Shiyao, Kang Yao, Lv Jun, Lin Yichen, Zhao Tingxiao, Yao Longtao, Zhou Hong, Zhou Kai

Molecular subtypes and nomogram for predicting the prognosis of cervical cancer based on a matrix-immune signature

Yuanyuan Liao, Qidan Huang, Guqun Shen, Yalikun Muhanmode, Xiaolin Luo, Fen Li, Mengke Wen, Jihong Liu, He Huang

Natural killer (NK) cells-related gene signature reveals the immune environment heterogeneity in hepatocellular carcinoma based on single cell analysis

Zhirong Ye, Wenjun Li, Hao Ouyang, Zikang Ruan, Xun Liu, Xiaoxia Lin, Xuanting Chen

Rutin suppresses the malignant biological behavior of gastric cancer cells through the Wnt/β-catenin pathway

Hui Huang, Jianguo Shi, Wei Chen, Lei Liu

The role of KLF5 in gut microbiota and lung adenocarcinoma: unveiling programmed cell death pathways and prognostic biomarkers

Qingliang Fang, Meijun Xu, Wenyi Yao, Ruixin Wu, Ruiqin Han, Satoru Kawakita, Aidan Shen, Sisi Guan, Jiliang Zhang, Xiuqiao Sun, Mingxi Zhou, Ning Li, Qiaoli Sun, Chang-Sheng Dong

Single-cell RNA sequencing explored potential therapeutic targets by revealing the tumor microenvironment of neuroblastoma and its expression in cell death

Lei Sun, Wenwen Shao, Zhiheng Lin, Jingheng Lin, Fu Zhao, Juan Yu

Knocking down RAD51AP1 enhances chemosensitivity by inhibiting the self-renewal of CD133 positive ovarian cancer stem-like cells

Si-heng Zeng, Zhi-qiang Yan, Qing Ren, Li-hui Lin, Zhen Chen

Development and experimental verification of novel angiogenesis related prognostic model and immune infiltration characterization in osteosarcoma

Shengquan Ren, Rongfang Pan, Zhengdan Wang

CCL17, CCL22 and their receptor CCR4 in hematologic malignancies

Shasha Zou, Bo Liu, Yonghuai Feng

Identification of biomarker associated with Trop2 in breast cancer: implication for targeted therapy

Jianguo Lai, Shuxuan Deng, Jiyuan Cao, Yongqi Ren, Zanmei Xu, Xiaofang Qi, Mian Xu, Ning Liao

Unveiling the role of PSMA5 in glioma progression and prognosis

Wei Liu, Bo Jia, Zan Wang, Chengcai Li, Nanding Li, Jie Tang, Jiwei Wang

Addressing the critical gap: conscious sedation for pediatric oncology patients in LMICs

Syed Ibrahim Bukhari, Gashaw Arega, Sadaf Altaf

Adverse drug reactions and drug-related problems with supportive care medications among the oncological population

Batoul Barari Tajani, E. Maheswari, Vinayak V. Maka, Anjana S. Nair

Single-cell RNA sequencing reveals the change in cytotoxic NK/T cells, epithelial cells and myeloid cells of the tumor microenvironment of high-grade serous ovarian carcinoma

Lingnan Meng, Shujuan Sun

A useful mTORC1 signaling-related RiskScore model for the personalized treatment of osteosarcoma patients by using the bulk RNA-seq analysis

Hongxia Chen, Wei Wang, Shichuan Chang, Xiaoping Huang, Ning Wang

LINC00461 promotes bladder cancer cells EMT through miR-518b/HNRNPUL1 axis

Yijie Zhou, Keyuan Zhao, Junlong Li, Chao Peng, Jing Jin, Jiajun Chen, Yulei Li, Gang Xu, Shouhua Pan

A cancer-associated fibroblasts related risk score (CAFscore) helps to guide prognosis and personal treatment for Glioblastoma

Lili Wu, Qinjian Liu, Guoyin Li, Weidong Shi, Weifeng Peng

Modulation of esophageal squamous cell carcinoma progression: the impact of CCR7 on JAK2/STAT3 signaling pathway

Xuewen Zhang, Yuji An, Dongmei Mai, Wan Huang, Weian Zeng

RNA sequencing and multiplexed immunohistochemistry reveal the factors for postoperative recurrence of stage IB-IIA cervical squamous cell carcinoma

Meiyao Wu, Baixue Li, Lina Shi, Lingling Yang, Chuqiao Liang, Tianhong Wang, Xiujie Sheng

  • Open Access
  • Research

Expression and biological significance of topoisomerase II α (TOP2A) in oral squamous cell carcinoma

Xujie Cheng, Yuxing Wei, Limei Deng, Hao Dong, Huiping Wei, Cheng Xie, Yangjuan Tuo, Meiyu Chen, Hao Qin, Yong Cao

Co-targeting NRF2 potentially enhances the in vitro anticancer effects of paclitaxel in gastric cancer cells

Shima Hasani, Mohammad Khalaj-Kondori, Sahar Safaei, Mohammad Amini, Negin Riazi-Tabrizi, Mohadeseh Maghsoudi, Behzad Baradaran

Short-chain fatty acids play a positive role in colorectal cancer

Gang Liu, Jingtong Tang, Jianping Zhou, Ming Dong

A new exploration: characterization of the differentiation trajectory of prostate cancer cells

Jiyu Yang, Changyou Wang, Xiao Ma, Jie Li, Haoran Yuan, Renzhen Tan, Ling Ling, Xianchun Zhou

Does circulating tumor DNA apply as a reliable biomarker for the diagnosis and prognosis of head and neck squamous cell carcinoma?

Negin Ghiyasimoghaddam, Navidreza Shayan, Hanieh Alsadat Mirkatuli, Mohammadhasan Baghbani, Nima Ameli, Zeynab Ashari, Nooshin Mohtasham

CT and MR imaging characteristics of primary hepatic lymphoma

Yaodan Zhang, Jianmin Cui, Zhaoxiang Ye, Xubin Li

Identification of circadian clock-related immunological prognostic index and molecular subtypes in prostate cancer

Lu Che, Dengxiong Li, Jie Wang, Zhouting Tuo, Koo Han Yoo, Dechao Feng, Yun Ou, Ruicheng Wu, Wuran Wei

  • Open Access
  • Review

KIF18B: an important role in signaling pathways and a potential resistant target in tumor development

Shicheng Chen, Bo Yu, Guo TU DU, Tian Yu Huang, Neng Zhang, Ni Fu

Deciphering the impact of aggregated autophagy-related genes TUBA1B and HSP90AA1 on colorectal cancer evolution: a single-cell sequencing study of the tumor microenvironment

Qianping Xu, Chao Liu, Hailin Wang, Shujuan Li, Hanshen Yan, Ziyang Liu, Kexin Chen, Yaoqin Xu, Runqin Yang, Jingfang Zhou, Xiaolin Yang, Jie Liu, Lexin Wang

LncRNA DNAH17-AS1 promotes gastric cancer proliferation and radioresistance by sponging miR-202-3p to upregulate ONECUT2

Yugang Ge, Hui Cang, Jian Xiao, Hongshuai Wu, Biao Wang, Qing Shao

Pyroptosis-associated genes and tumor immune response in endometrial cancer

Xiaodi Gong, Zhifeng Wang, Jiahao You, Jinghai Gao, Kun Chen, Jing Chu, Xiaoxin Sui, Jianhong Dang, Xiaojun Liu

Identifying hub genes for chemo-radiotherapy sensitivity in cervical cancer: a bi-dataset in silico analysis

Yanhong Wang, Yi Ouyang, Xinping Cao, Qunrong Cai

A scoring model for the expression of genes related to programmed cell death predicts immunotherapy response and prognosis in lung adenocarcinoma

Runan Jia, Xiaolong Liang, Jianfei Tu, Hongyuan Yang

  • Open Access
  • Research

Exploring the relationship between the interleukin family and lung adenocarcinoma through Mendelian randomization and RNA sequencing analysis

Fei-Hang Zhi, Wei Liu, Hao-Shuai Yang, Hong-He Luo, Yan-Fen Feng, Yi-Yan Lei

Pan-cancer analysis of m1A writer gene RRP8: implications for immune infiltration and prognosis in human cancers

Zhihui Huang, Koo Han Yoo, Duohui Li, Qingxin Yu, Luxia Ye, Wuran Wei

The impact of everolimus on hematologic parameters in patients with renal angiomyolipoma associated with tuberous sclerosis complex

Dongxu Qiu, Wenda Wang, Yang Zhao, Zhan Wang, Xu Wang, Zhangcheng Liao, Yushi Zhang

CD206 accelerates hepatocellular carcinoma progression by regulating the tumour immune microenvironment and increasing M2-type polarisation of tumour-associated macrophages and inflammation factor expression

Zhiyuan Mao, Yalin Han, Yinglin Li, Li Bai

Latrophilin-3 as a downstream effector of the androgen receptor induces bladder cancer progression

Takuro Goto, Yuki Teramoto, Yujiro Nagata, Hiroshi Miyamoto

  • Open Access
  • Analysis

Unveiling the impact of cell death-related genes and immune dynamics on drug resistance in lung adenocarcinoma: a risk score model and functional insights

Yuanyuan Xiao, Shancheng He, Baochang Xie, Wenqi Zhao, Dengliang Ji

Prognosis evaluation and efficacy analysis of different treatment options for patients with visceral pleural invasion in stage IIA–IIB lung cancer

Qi Liu, Liusheng Wu, Xiangyu Wang, Yu Feng, Ying Wang, Jun Yan, Xiaoqiang Li

Intratumoral microbiota of pancreatic ductal adenocarcinoma impact patient prognosis by influencing tumor microenvironment

Jingze Leng, Hengyi Xu, Xiaoyu Liu, Yufan Yang, Chun Ning, Lejia Sun, Jiangming Qu, Xindi Ke, Xun Lan

New findings on the incidence and management of CNS adverse reactions in ALK-positive NSCLC with lorlatinib treatment

Fanfan Chu, Wenxi Zhang, Hong Hu

Single-cell profiling uncovers proliferative cells as key determinants of survival outcomes in lower-grade glioma patients

Jianming Peng, Qing Zhang, Xiaofeng Zhu, Zhu Yan, Meng Zhu

Elevated BEAN1 expression correlates with poor prognosis, immune evasion, and chemotherapy resistance in rectal adenocarcinoma

Tiannake Shapaer, Yi Chen, Yipeng Pan, Zhimin Wu, Tuoxian Tang, Zeliang Zhao, Xiangyue Zeng

  • Open Access
  • NSCLC
  • Research

Predicting the T790M mutation in non-small cell lung cancer (NSCLC) using brain metastasis MR radiomics: a study with an imbalanced dataset

Wen-Feng Wu, Kuan-Ming Lai, Chia-Hung Chen, Bai-Chuan Wang, Yi-Jen Chen, Chia-Wei Shen, Kai-Yan Chen, Eugene C. Lin, Chien-Chin Chen

Prognostic determinants in cancer survival: a multidimensional evaluation of clinical and genetic factors across 10 cancer types in the participants of Genomics England’s 100,000 Genomes Project

Jurgita Gammall, Alvina G. Lai

tRF-Leu reverse breast cancer cells chemoresistance by regulation of BIRC5

Li Sun, Yu-Wen Jiao, Fu-Qi Cui, Jin Liu, Zhong-Ya Xu, Dong-Lin Sun

  • Open Access
  • Research

Longitudinal needs and cancer knowledge in Swiss childhood cancer survivors transitioning from pediatric to adult follow-up care: results from the ACCS project

Luca Buehlmann, Maria Otth, Katrin Scheinemann

Clinical efficacy and immune response of BCL-2 inhibitors combined with hypomethylating agents in the treatment of acute myeloid leukemia

Xiaohuan Peng, Jianing Yu, Futian Tang, Yanhong Li, Jun Bai, Lijuan Li, Liansheng Zhang

Nanoquercetin based nanoformulations for triple negative breast cancer therapy and its role in overcoming drug resistance

Adyasa Samantaray, Debasish Pradhan, Nalini Ranjan Nayak, Saurabh Chawla, Bandana Behera, Lalatendu Mohanty, Saroj Kanta Bisoyi, Sabnam Gandhi

Evaluation of circulating plasma proteins in prostate cancer using mendelian randomization

Long Cheng, Zeming Qiu, Xuewu Wu, Zhilong Dong

Prognostic aging gene-based score for colorectal cancer: unveiling links to drug resistance, mutation burden, and personalized treatment strategies

Ling Duan, Yang Xia, Rui Fan, Yuxi Shuai, Chunmei Li, Xiaoming Hou

  • Open Access
  • Research

Comprehensive analysis of clinicopathological characteristics in oral squamous cell carcinoma arising from oral submucous fibrosis: a retrospective study

Yiyu Zeng, Jinyu Luo, Moxin Zi, Shanshan Jiang, Wenhui Ge, Yi Yu, Niya Chen, Jiaming Lin, Xiaoyan Xie

Identification and validation of a novel five-gene signature in high-risk MYCN-not-amplified neuroblastoma

Jin-Xia Wang, Hong-Yang Zhang, Zi-Jun Yan, Zi-Yang Cao, Jing-Bo Shao, Lin Zou

Characterizing m6A modification factors and their interactions in colorectal cancer: implications for tumor subtypes and clinical outcomes

Weidong Sun, Yingchao Su, Zhiqiang Zhang

Analysis of the role of CHPF in colorectal cancer tumorigenesis and immunotherapy based on bioinformatics and experiments

Qingyu Song, Pengchao Wang, Jingyu Wu, Ming Lu, Qingcheng Xia, Yexin Shi, Zijun Wang, Xiang Ma, Qinghong Zhao

A reference for selecting an appropriate method for generating glioblastoma organoids from the application perspective

Jing Liang, Peng He

Conditional survival estimates for ependymomas reveal the dynamic nature of prognostication

Chenjun Sun, Zhihao Yang, Zhiwei Gu, Hua Huang

Clinical characteristics and genomic profiling of outpatients with endometrial cancer at a Chinese tertiary cancer center

Zheng Feng, Hao Wen, Yaqiong Chen, Xiaojun Chen, Rui Bi, Xiaohua Wu, Jin Li, Xingzhu Ju

  • Open Access
  • Research

Multicenter cohort analysis of anoikis and EMT: implications for prognosis and therapy in lung adenocarcinoma

Lu Yin, Zhanshuo Zhang, Zhu Yan, Qiuyue Yan

Utilizing machine learning algorithms for predicting risk factors for bone metastasis from right-sided colon carcinoma after complete mesocolic excision: a 10-year retrospective multicenter study

Yuan Liu, Yuankun Liu, Shuting Wang, Sen Niu, Langyu Wang, Jiaheng Xie, Ning Zhao, Songyun Zhao, Chao Cheng, Teng Dai

Ailanthone suppresses cell proliferation of renal cell carcinoma partially via inhibition of EZH2

Jianbing Zhu, Guangcheng Dai, Ting Chen, Yibin Zhou, Yachen Zang, Lijun Xu, Lu Jin, Jin Zhu

hnRNPA1 promotes the metastasis and proliferation of gastric cancer cells through WISP2-guided Wnt/β-catenin signaling pathway

Chenyang Jiang, Dengfei Xu, Hao Feng, Zirui Ren, Xiang Li, Yuming Chen, Jifeng Yu, Shundong Cang

  • Open Access
  • Research

The impact of histological subtype on postoperative recurrence pattern and timing in locally advanced esophagogastric junction cancer

Shinsuke Maeda, Masaho Ota, Shunichi Ito, Kei Hosoda

Surgical outcomes following neoadjuvant chemotherapy with and without immunotherapy in patients with triple-negative breast cancer

Anouchka Coste Holt, Courtney A. Smith, Maurice J. Berkowitz, Jennifer L. Baker, Nicholas P. McAndrew, Nimmi S. Kapoor

HPV-ferroptosis related genes as biomarkers to predict the prognosis of cervical cancer

Songtao Han, Senyu Wang, Yuxia Li, YuJiao He, Jing Ma, Yangchun Feng

Identification of prognostic biomarkers in neuroblastoma using WGCNA and multi-omics analysis

Yuhan Ke, Wenliang Ge

Unraveling the immune landscape of lung adenocarcinoma: insights for tailoring therapeutic approaches

Changjiang Wu, Wangshang Qin, Wenqiang Lu, Jingyu Lin, Hongwei Yang, Chunhong Li, Yiming Mao

The antioxidant and selective apoptotic activities of modified auraptene-loaded graphene quantum dot nanoparticles (M-AGQD-NP)

Parisa Golestani, Masoud Homayouni Tabrizi, Ehsan Karimi, Mozhgan Soltani

Trends in focal therapy for localized prostate cancer: a bibliometric analysis from 2014 to 2023

Zhi-Yu Xia, Si-Han Zhang, Jian-Xuan Sun, Shao-Gang Wang, Qi-Dong Xia

Gut commensal Alistipes as a potential pathogenic factor in colorectal cancer

Jingjing Fu, Guangyao Li, Xiaoping Li, Shasha Song, Lijuan Cheng, Beibei Rui, Lei Jiang

Exploring the heterogeneity of interstitial cells of Cajal and their properties in gastrointestinal mesenchymal tumors applying single-cell RNA sequencing analysis

Yongjun Zhu, Rui Zhang, Shipai Zhang, Haijun Hu

Identification of hsa-miR-193a-5p-SURF4 axis related to the gut microbiota-metabolites- cytokines in lung cancer based on Mendelian randomization study and bioinformatics analysis

Jie Yu, Sibo Meng, Tiantian Xuan, Zhanmei Wang, Linli Qu, Fangli Cao, Jiaxin Li

A nomogram for enhanced risk stratification for predicting cervical lymph node metastasis in papillary thyroid carcinoma patients

Lingxin Deng, Dilidaer Muhanhali, Zhilong Ai, Min Zhang, Yan Ling

Optimal cut-off values and diagnostic significance of clinical laboratory indicators in newly diagnosed multiple myeloma

Manning Li, Han Wu, Chunyi Shou, Ye Peng, Xiaolu Song, Wang Ying, Yirui Chen, Xiangmin Tong

ENO2 in progression and treatment of colon adenocarcinoma: integrative bioinformatics analysis on non-apoptotic cell death

Jia Tang, Weiqiang Wang, Guangming Tang

Regulator of nonsense transcripts 3B is a prognostic biomarker and associated with immune cell infiltration in lung squamous cell and hepatocellular carcinoma

Pengcheng Li, Mi Zhou, Xiaoli Gan, Chaoyi Yuan, Ganxun Li, Guan-nan Jin, Ze-yang Ding

Recent progress in microRNA research for prostate cancer

Fan Yuan, Yue Hu, Yanmei Lei, Lingna Jin

Bibliometric analysis of endoplasmic reticulum stress in hepatocellular carcinoma: trends and future directions

Yaping Zhang, Yinting Tian, Zheyuan Wang, Yawu Zhang, Gennian Wang

Exploring copper metabolism-induced cell death in gastric cancer: a single-cell RNA sequencing study and prognostic model development

Yi Chen, Yunmei Liao, Lang Huang, Zhibin Luo

Machine learning-based prediction of gastroparesis risk following complete mesocolic excision

Wei Wang, Zhu Yan, Zhanshuo Zhang, Qing Zhang, Yuanyuan Jia

Thoracic epithelioid inflammatory myofibroblastic sarcoma: a rare and aggressive disease with case report and literature review

Linke Yang, Pei Li, Runze Liu, Baomin Feng, Huiqing Mao, Xiaoyong Tang, Guangjian Yang

  • Open Access
  • SCLC
  • Research

A comparative study of ProGRP and CEA as serological markers in small cell lung cancer treatment

Mingjie Yu, Ping Wang

Precision molecular insights for prostate cancer prognosis: tumor immune microenvironment and cell death analysis of senescence-related genes by machine learning and single-cell analysis

Yuni Wu, Ran Xu, Jing Wang, Zhibin Luo

Expression assays of selected lncRNAs in non-functioning pituitary adenomas

Parisa Esmaeili Motlagh, Soudeh Ghafouri-Fard, Solat Eslami, Guive Sharifi, Mohammad Taheri

B3GALT4 modulates tumor progression and autophagy by AKT/mTOR signaling pathway in breast cancer

Yongliang Sha, Huijie Zhuang, Jin Shi, Song Ge, Shiqing He, Yiqiu Wang, Li Ma, Hao Guo, Hui Cheng

Exploring the therapeutic potential of cannabinoids in cancer by modulating signaling pathways and addressing clinical challenges

Manal Bint Faiz, Faiza Naeem, Muhammad Irfan, Muhammad Adeel Aslam, Leticia M. Estevinho, Dilek Arslan Ateşşahin, Asma M. Alshahrani, Daniela Calina, Khushbukhat Khan, Javad Sharifi-Rad

Identification of GPNMB in endometrial cancer based on pan-cancer analysis and in vitro validation

Xiaoqian Tuo, Jialan Chen, Cuipei Hao, Xiaole Dai, Jiayi Zhu, Siqi Tian, Yan Zhang, Fan Wang

High expression of ARHGEF5 predicts unfavorable prognosis in acute myeloid leukemia

Haitao Xu, Dangui Chen, Jia Lu, Long Zhong

  • Open Access
  • Analysis

Identification of key ferroptosis genes and subtypes in kidney renal clear cell carcinoma

Biao Wang, Zhuo Wei, Man Xu, Hui Shu, Zheqi Fan

Aeromonas veronii-associated bacteremia in the course of treatment of acute myeloid leukemia: a case report and review of the literature

Jiashan Zhao, Tianjiao Wu, Songyun Wang, Huirui Wang

Monte Carlo dosimetry study of newly designed shielded applicators for intensity modulated brachytherapy of cervical and vaginal cancers

Erfan Saatchian, Shahrokh Nasseri, Sare Hosseini, Hamid Gholamhosseinian

Development of brain metastases in patients managed with non-curative thoracic radiotherapy for stage II/III non-small cell lung cancer

Carsten Nieder, Siv Gyda Aanes, Luka Stanisavljevic, Bård Mannsåker

Identification of BBC3 as a novel indicator for predicting prostate cancer development and olaparib resistance

Junjie Ma, Xin Qin, Wei Le, Xi Chen, Xiao Wang, Chengdang Xu

Predicting angiogenesis in adrenal pheochromocytoma: the role of modified parameters from contrast-enhanced CT

Xing Xing, Shao-ping Cheng, Jin-bai Huang

Diagnostic value of serum human epididymal secretory protein 4 for endometrial cancer: a systematic review and meta analysis

Jie Yuan, Chen Xu, Chunyong Liu, Ruiling Yan

Super learner model for classifying leukemia through gene expression monitoring

Sharanya Selvaraj, Alhuseen Omar Alsayed, Nor Azman Ismail, Balasubramanian Prabhu Kavin, Edeh Michael Onyema, Gan Hong Seng, Arinze Queen Uchechi

The application of nanoparticles in delivering small RNAs for cancer therapy

Tong Zhou, Jun-Ming Qiu, Xue-Jia Han, Xia Zhang, Pingyu Wang, Shu-Yang Xie, Ning Xie

Unveiling the therapeutic promise of EphA2 in glioblastoma: a comprehensive review

Caohang Qiu, Ning Sun, Shan Zeng, Ligang Chen, Feilong Gong, Junjie Tian, Yu Xiong, Lilei Peng, Haiping He, Yang Ming

Examining the influence of tumor-infiltrating macrophages on breast cancer outcomes and identifying relevant genes for diagnostic purposes

Xiaoyun Zhang, Cheng Peng, Xuesong Xiong, Jianchun Lian

  • Open Access
  • Analysis

Actin like 6A is a prognostic biomarker and associated with immune cell infiltration in cancers

Yi He, Ganxun Li, Yu Wu, Ning Cai, Zeyu Chen, Bin Mei, Xiaoping Chen, Bixiang Zhang, Guannan Jin, Zeyang Ding

  • Open Access
  • Analysis

Pan-cancer analysis of the prognostic and immunological role of hippo-YAP signaling pathway

Jing Yang, Cheng Yang, Guang Yang, Ronglin Wang, Junqiang Li, Yang Song

Deciphering the role of sphingolipid metabolism in the immune microenvironment and prognosis of esophageal cancer via single-cell sequencing and bulk data analysis

Rongzhang He, Jing Tang, Haotian Lai, Tianchi Zhang, Linjuan Du, Siqi Wei, Ping Zhao, Guobin Tang, Jie Liu, Xiufang Luo

Knowledge-map and research trends of circulating tumor cells in breast cancer: a scientometric analysis

Jinan Shi, Yin Duan

AI-powered genomic mutation signature for predicting immune checkpoint inhibitor therapy outcomes in gastroesophageal cancer: a multi-cohort analysis

Bingyin Yang, Cuie Cheng, Jingfang Zhou, Haoxiang Ni, Haoran Liu, Yiwei Fu, Rui Li

  • Open Access
  • Research

Exploring a new signature for lung adenocarcinoma: analyzing cuproptosis-related genes through Integrated single-cell and bulk RNA sequencing

Jiangtao Liu, Wei Xia, Feng Xue, Chen Xu

Comprehensive analysis to identify IL7R as a immunotherapy biomarker from pan-cancer analysis to in vitro validation

Jiafeng Liang, Lucheng Zhu, Jiawei Li, Kan Wu, Minna Zhang, Shenglin Ma, Xueqin Chen, Bing Xia

  • Open Access
  • NSCLC
  • Research

Codonopsis pilosula polysaccharide suppresses the progression of non-small cell lung cancer by triggering NLRP3/GSDMD-dependent pyroptosis

Shaoyan Huang, Quanxing Li, Yaobo Song

Novel biomarkers and drug correlations of non-canonical WNT signaling in prostate and breast cancer

Yongming Huang, Meiyin Fan, Yushuai Liu, Xiaoying Jiang, Kevin Du, Alice Wu, Qingyi Li, Yingying Wu, Jiaqian Liang, Keshan Wang

Evaluation of the clinical significance of lymphocyte subsets and myeloid suppressor cells in patients with renal carcinoma

Yan Li, Zhiping Wu, Chen Ni, Yueda Li, Ping Wang

Exploring the interaction between immune cells in the prostate cancer microenvironment combining weighted correlation gene network analysis and single-cell sequencing: An integrated bioinformatics analysis

Danial Hashemi Karoii, Sobhan Bavandi, Melika Djamali, Ali Shakeri Abroudi

The role of the ceRNA network mediated by lncRNA SNHG3 in the progression of cancer

Ying Peng, Xi-Dai Long

  • Open Access
  • Review

Nanocurcumin in cancer treatment: a comprehensive systematic review

Meshkat boroughani, Amir Kian Moaveni, Parsa Hatami, Neda Mansoob Abasi, Seyedeh Asrin Seyedoshohadaei, Arash Pooladi, Yousef Moradi, Ramyar Rahimi Darehbagh

Predicting gene signature in breast cancer patients with multiple machine learning models

Fangfang Zhu, Dafang Xu

  • Open Access
  • Review

Recent advances in ctDNA detection using electrochemical biosensor for cancer

Sahil Kumar, Renu Poria, Deepak Kala, Rupak Nagraik, Yashika Dhir, Sunny Dhir, Bharat Singh, Naveen Kumar Kaushik, Md Salik Noorani, Deepak Kumar, Shagun Gupta, Ankur Kaushal

Screening of prognostic factors and survival analysis based on histological type for perimenopausal endometrial carcinoma treated with hysterectomy

Luyao Kang, Gaili Ji, Duan Liu, Yaping Wang, Jie Meng, Hongyu Li

Identification of key genes participating in copper-diethyldithiocarbamate-related cell death process and predicting the development of prostate cancer

Xin’an Wang, Chengdang Xu, Junjie Ma, Xiao Wang, Xi Chen

Multi-scale transcriptomics reveals that specific tumor cells promote lung adenocarcinoma metastasis through crosstalk with the microenvironment

Qi Cai, Lin Shi, Mengwei Zhang, Peng Chen

Development of a disulfidptosis-related prognostic model for endometrial cancer with potential therapeutic target

Chunmei Li, Xuefei Fan, Xue Wang, Yulan Yao, Bing Huang, Linlin Chen, Lu Cao, Tao Peng, Yingying Lin, Rong Cai

Photodynamic therapy with intratumoral injection of photosensitizers combined with immunotherapy brings hope to patients with refractory cutaneous malignant ulcers

Dan Tian, Chong Teng, Yanju Lv, Xiaozhuo Duan, Yi Wang, Xiaowei Song, Qiuying Jiang, Dayong Huang, Tao Xin, Yu Yang, Li Li

Role of collateral vessels on contrast-enhanced computed tomography in predicting metastatic potential for small renal cell carcinoma

Masato Yanagi, Tomonari Kiriyama, Jun Akatsuka, Yuki Endo, Yuka Toyama, Go Kimura, Taiji Nishimura, Yukihiro Kondo

Identification of KLHL17 as a prognostic marker for prostate cancer based on single-cell sequencing and in vitro/in vivo experiments

Qingyu Zhou, Dan Guo, Tong Shen, Huamao Jiang

Radiosensitivity in individuals with tuberous sclerosis complex

Lukas Kuhlmann, Jenny Stritzelberger, Rainer Fietkau, Luitpold V. Distel, Hajo M. Hamer

  • Open Access
  • Research

Comparative study of oxidative stress in cancer patients occupationally exposed to the mixture of pesticides

Anupama Ojha, Shashank Shekhar, Poonam Gupta, Sonali Jaiswal, Sarad Kumar Mishra

Thromboembolism during immune checkpoint inhibitor therapy: frequency and risk factors

Takayuki Ide, Taisuke Araki, Tomonobu Koizumi

NFYA-mediated promotion of castration-resistant prostate cancer progression through EGR4 regulation

Guijiang Sun, Yi Shao, Qianwang Ma, Shengju Song, Yutong Chen, Yang Li, Yue Gao, Haitao Wang, Zhiqun Shang

Colorectal cancer in ulcerative colitis after liver transplantation for primary sclerosing cholangitis: a systematic review and pooled analysis of oncological outcomes

Roberta Angelico, Leandro Siragusa, Francesca Blasi, Vittoria Bellato, Michela Mineccia, Elisabetta Lolli, Giovanni Monteleone, Giuseppe S. Sica

T cell exhaustion methylation signature drives differential immune responses in glioblastoma

Feng Chen, Wen-Bo Qian, Zhen-Hua Chen, Jun Qian, Chun Luo

Effectiveness of radiotherapy in delaying treatment changes in primary or secondary immunorefractory oligoprogressive patients: preliminary results from a single-center study

Valentina Zagardo, Emanuele Martorana, Mandara Harikar, Stefano Pergolizzi, Gianluca Ferini

Integrative analysis of multiple cell death model for precise prognosis and drug response prediction in gastric cancer

Weiping Su, Xunyang Shi, Xinhua Wen, Xuanxuan Li, Jingyu Zhou, Yangying Zhou, Feng Ren, Kuo Kang

CircTSN promotes the proliferation and metastasis of gastric cancer through the miR-1825/SLC38A2 signaling axis

Xuqiang Dong, Tianyu Cheng, Lijun Zhang, Liqun Song, Chao Shi

Analysis of the association between immune-related adverse events and the effectiveness in patients with advanced non-small-cell-lung cancer

Haiyan Chen, Yijiao Xu, Jianying Liu, Shuwen Yang, Hongni Jiang, Zhisheng Chen

Development and validation of a prognostic model for colon cancer based on mitotic gene signatures and immune microenvironment analysis

Changhao Gu, Lulu Jin, Xiaoyan Lv, Cheng Wang, Congle Wen, Xiuxiu Su

Exploring the significance and potential mechanisms of hippo pathway-associated genes in prognosis of glioma patients

XuKai Liu, Hongjun Fan, Zebo Chen, Chao Liu

A basement membrane-related signature for prognosis and immunotherapy benefit in bladder cancer based on machine learning

Yunuo Zhang, Jingna Wu, Xinhong Liang

Exploring the role of ADAMTSL2 across multiple cancer types: A pan-cancer analysis and validated in colorectal cancer

Qing-xin Yu, Rui-cheng Wu, Jie Wang, Zhou-Ting Tuo, Jun Yang, Yong-ping Zhang, Jing Jin, Quan Yuan, Chun-nian Wang, De-chao Feng, Deng-xiong Li

Global research and current trends on nanotherapy in lung cancer research: a bibliometric analysis of 20 years

Pooja Singh, Prabhakar Semwal, Baby Gargi, Sakshi Painuli, Michael Aschner, Khalaf F. Alsharif, Haroon Khan, Rakesh Kumar Bachheti, Limenew Abate Worku

Prognostic risk model of LIHC T-cells based on scRNA-seq and RNA-seq and the regulation of the tumor immune microenvironment

Shoupeng Ding, Xiaomei Yi, Jinghua Gao, Chunxiao Huang, Shouzhao Zheng, Lixian Wu, Zihan Cai

  • Open Access
  • Research

The unique CARWL score stratifies locally advanced nasopharyngeal cancer patients receiving concurrent chemoradiotherapy into risk groups for radiation-induced trismus

Sukran Senyurek, Efsun Somay, Nilufer Kilic Durankus, Sibel Bascil, Duriye Ozturk, Ugur Selek, Erkan Topkan

Identification of novel diagnostic biomarkers associated with liver metastasis in colon adenocarcinoma by machine learning

Long Yang, Ye Tian, Xiaofei Cao, Jiawei Wang, Baoyang Luo

STARD7 could be an immunological and prognostic biomarker: from pan-cancer analysis to hepatocellular carcinoma validation

Jie Hu, Qiu Jiang, Weili Mao, Songyang Zhong, Huayu Sun, Kaili Mao

Long noncoding RNA DDX11-AS1 represses sorafenib-induced ferroptosis in hepatocellular carcinoma cells via Nrf2-Keap1 pathway

Liang Wang, Liming Wang

Application of artificial intelligence model in pathological staging and prognosis of clear cell renal cell carcinoma

Jing Yao, Lai Wei, Peipei Hao, Zhongliu Liu, Peijun Wang

Selection determines therapeutic effects: a retrospective analysis of the application of different frailty tools in elderly patients with multiple myeloma

Yujun Li, Songying Zhao, Jianmei Xu, Jiangbo Zhang, Jing Wang, Huimei Guo, Liyang Liu, Hua Xue

  • Open Access
  • Review

Deciphering the IGF2BP3-mediated control of ferroptosis: mechanistic insights and therapeutic prospects

Wenjuan Zhang, Hui Liu, Changrong Ren, Kaiqian Zhang, Shuhan Zhang, Shifan Shi, Zhiyan Li, Jian Li

RBMS1 interference inhibits malignant progression of glioblastoma cells and promotes ferroptosis

Xiaosong Liang, Gang Wang, Chunxiao Xue, Yifu Zhou

EBNA1BP2 identified as potential prognostic biomarker for multiple tumor types in pan-cancer analysis

Li-Yue Sun, Yu-Ying Jiang, Xin-Xin Zeng, Ju Shen, Ke-Xin Xian, Quan-An Xu, Xian Xu, Lei Liang, Xu-Hui Zhang

Immunotherapy and pan-apoptotic characterization of the tumor microenvironment in gastric cancer (STAD): a single-cell multidimensional analysis

Sheng Zhang, Jianhong Wang, Huan Zhang, Benhua Li, Shun Gao

Identified a novel prognostic model of HCC basing on virus signature for guiding immunotherapy

Shizhuan Huang, Dehai Wu, Guanqun Liao, Ming Liang, Yaohui Zhang, Haotian Wu, Daowei Tang, Dixiang Wen, Bo Jiang, Shan Yu, Sheng Tai

  • Open Access
  • Analysis

SPECC1 as a pan-cancer biomarker: unraveling its role in drug sensitivity and resistance mechanisms

Dongwei Liu, Xidi Wang, Lingfei Cui, Mingxia Zhang, Kefeng Lei, Nijiati Aierken

  • Open Access
  • Research

Gingerol acts as a potent radiosensitizer in head and neck squamous cell carcinoma

Cleopatra Rutihinda, Ryma Haroun, Juan Pablo Ordonez, Saad Mohssine, Huda Oweida, Muskaan Sharma, Mohamed Fares, Nancy Ruiz-Dominguez, Maria Fernanda Meza Pacheco, Sahar Naasri, Nour Elhouda Saidi, Ayman J. Oweida

Clinical efficacy of combined goserelin and anastrozole in neoadjuvant endocrine therapy for premenopausal women with hormone receptor-positive breast cancer

Xu Han, Hui Li, Shui-Ying Zhou, Sha-Sha Dong, Gang-Ling Zhang

Keratin-15 high expression links with lymph node metastasis and poor survival prognosis in epithelial ovarian cancer patients

Xuqin Feng, Qian Wang

AURKA inhibition shows promise as a therapeutic strategy for ARID1A-mutant colorectal cancer

Rong-Sheng Qin, Chun-Tao Li, Fei Chen, Shu Luo, Chao Wang, Jie Li, Shan Xu, MingWei Kang, Hao-Wen Hu

The co-expression of Crohn’s disease and colon cancer network was analyzed by bioinformatics-CXCL1 tumour microenvironment and prognosis-related gene CXCL1

Zijuan Mao, Yuyang Gu, Ganxue Tao, Qiang Dai, Yangjie Xu, Zhenghua Fei

Title of the article: diagnostic markers for odontogenic tumors: an insight: a review

Varun Rastogi, Sandhya Chaurasia, Nisha Maddheshiya, Dilasha Dhungel

Advances in the role of membrane-bound transcription factors in carcinogenesis and therapy

JiaLi Deng, Jie Zhou, BinYuan Jiang

First reported advanced pancreatic cancer with hyperprogression treated with PD-1 blockade combined with chemotherapy: a case report and literature review

Ya-Zhou Wang, Mao-Zhen Peng, Yao-Lin Xu, Ying Ying, Lin-Hui Tang, Hua-Xiang Xu, Jun-Yi He, Liang Liu, Wen-Quan Wang

  • Open Access
  • Review

Current insights and future directions of Li-Fraumeni syndrome

Mohammad-Salar Hosseini

  • Open Access
  • Research

Expression of CLDN1 and EGFR in PTC

JunJie Wu, YouMei Wang, Lei Yan, YaWen Dong

MicroRNA-34a negatively regulates Netrin1 and mediates MEK/ERK pathway to regulate chemosensitivity of gastric cancer cells

Haiping Liu, Limin Wang

Reconstruction of cancer marker analysis with holistic anatomical precision implicates heterogeneity development during breast tumor progression

Zhicheng Ge, Jing Wang, Libing He, Meng Zhao, Yang Si, Siyuan Chang, Guoyan Zhang, Shan Cheng, Wei Ding

Preoperative discrimination of invasive and non-invasive breast cancer using machine learning based on automated breast volume scanning (ABVS) radiomics and virtual touch quantification (VTQ)

Lifang Fan, Yimin Wu, Shujian Wu, Chaoxue Zhang, Xiangming Zhu

Development trends and knowledge framework of artificial intelligence (AI) applications in oncology by years: a bibliometric analysis from 1992 to 2022

Murat Koçak, Zafer Akçalı

Comprehensive pan-cancer analysis of FUTs family as prognostic and immunity markers based on multi-omics data

Zexi Jia, Pan Liao, Bo Yan, Ping Lei

Exploring the interaction mechanisms between cervical carcinoma in situ and antibody-mediated immune responses through Mendelian randomization analysis

Junfei Li, Lihuang He, Qun He, Kaihong Xie, Hui Xie

Circ_0001047 inhibits prostate cancer progression and enhances abiraterone sensitivity via miR-122-5p/FKBP5/PHLPP1/AKT axis in vitro

Zhenjie Chen, Shi Fu, Yiqian Shan, Zexi He, Jun Gu, Haichao Wu, Jiawei Lin, Yinglong Huang, Haifeng Wang, Yangbai Lu, Mingxia Ding

Application of large-scale and multicohort plasma proteomics data to discover novel causal proteins in gastric cancer

Weihao Tang, Xiaoke Ma

B cell deficiency in thymoma tissues of Good’s syndrome patients

Junwu Zhang, Jinyao Ni, Liyan Li, Yanxia Chen, Jinlin Liu

EFNA5 suppresses cell proliferation and tumor metastasis in hepatoma via epithelial-to-mesenchymal transition

Zhiqin Zhu, Shulu Hu, Xingyi Zhong, Yangfeng Zhang, Xiuqiong Wu, Junhao Lin, Fengsheng Chen

  • Open Access
  • Research

Potential role of heteroplasmic mitochondrial DNA mutations in modulating the subtype-specific adaptation of oral squamous cell carcinoma to cisplatin therapy

Amnani Aminuddin, Pei Yuen Ng, Chee Onn Leong, Suzana Makpol, Eng Wee Chua

  • Open Access
  • Laser
  • Review

Current opinions regarding the clinical utility of en bloc resection in the treatment of non-muscle invasive bladder cancer—a review of the literature

Wenbo Gao

Unraveling the causal association between lifestyle and metabolic factors with endometrial cancer: evidence from a Mendelian randomization study

Xu Zhang, Caiyu Pu, Li Wang, Xiaona Lin, Hansu Lai, Shanshan Wu, Jing Wan

LINC01518 predicts poor prognosis of prostate cancer and promotes its progression by regulating hsa-miR-320a/CNKSR2 axis

Guodong Chen, Zixin Chen

Metabolism: an important player in glioma survival and development

Ning Wang, Yiru Yuan, Tianhao Hu, Huizhe Xu, Haozhe Piao

Primary central nervous system lymphoma: a series report and literature review

Yueli Zou, Yaning Wu, Helin An, Mingzhao Song, Jingyi Zhang, Xiujun Yu, Yi Li

Integrated immunogenomic analyses of single-cell and bulk profiling construct a T cell-related signature for predicting prognosis and treatment response in osteosarcoma

Chicheng Niu, Weiwei Wang, Qingyuan Xu, Zhao Tian, Hao Li, Qiang Ding, Liang Guo, Ping Zeng

Non-invasive miRNAs for early detection and diagnosis of lacrimal adenoid cystic carcinoma

Xia Ding, Mingjiao Chen, Yan Liu, Tianyi Zhou, Yue Xing, Ming Lin, Jin Li

Venous thromboembolism and ovarian cancer risk: a Mendelian randomized study

Xiaolin Liu, Shan Wang, Hongwei Lv, Enli Chen, Jing Yu

  • Open Access
  • Research

Overexpression of a disintegrin and metalloproteinase 9 (ADAM9) in relation to poor prognosis of patients with oral squamous cell carcinoma

Shuangjiang Wu, Lang Cheng, Tao Luo, Anupong Makeudom, Lei Wang, Suttichai Krisanaprakornkit

  • Open Access
  • Retraction Note

Retraction Note: Silencing of long non-coding RNA TUC338 inhibits the malignant phenotype of nasopharyngeal cancer cells via modulating the miR-1226-3p/FGF2 axis

Jian Wang, Liping Li, Xue Jiang, Bin Wang, Xiaodong Hu, Weiwei Liu, Ying Zhang

Loss of miR-634 contributes to the formation FOXA1-positive triple negative breast cancer subtype

Feng Ren, Xiaoping Rui, Xianqiu Xiao

  • Open Access
  • NSCLC
  • Research

Optimizing lung cancer surgery in the elderly: sublobar resection versus lobectomy for early-stage non-small cell lung cancer patients aged 80 and above

Jianfeng Li, Hongjie Zhu, Nanzhi Luo, Wenjing Zhou, Fuqiang Dai, Xintian Wang, Xiaoli Wu

Treatment-free remission after discontinuation of tyrosine kinase inhibitors in patients with chronic myeloid leukemia in the chronic phase: a systematic review and meta-analysis

Zhenxiang Zheng, Hao Tang, Xinxia Zhang, Liling Zheng, Zhao Yin, Jie Zhou, Yangmin Zhu

A-to-I-edited miR-1251-5p restrains tumor growth and metastasis in lung adenocarcinoma through regulating TCF7-mediated Wnt signaling pathway

Shuhua Xu, Guoping Zhou, Qiyu He, Junning Ding, Xiaoli Liu, Youshuang Cheng, Yaqing Shen

Bioinformatic and experimental analyses of GATA3 and its regulatory miRNAs in breast Cancer

Fatemeh Roohy, Mehdi Moghanibashi, Sedigheh Tahmasebi

UBE2C promotes LUAD progression by ubiquitin-dependent degradation of p53 to inactivate the p53/p21 signaling pathway

Siyuan Huang, Xingya Li

The two-sided battlefield of tumour-associated macrophages in glioblastoma: unravelling their therapeutic potential

Jingwen Xiong, Xuancheng Zhou, Lanqian Su, Lai Jiang, Ziwei Ming, Can Pang, Claire Fuller, Ke Xu, Hao Chi, Xiaomei Zheng

Integrative analysis of bulk and single-cell transcriptomic data reveals novel insights into lipid metabolism and prognostic factors in hepatocellular carcinoma

Feiyu Qi, Guiming Zha, Yanfang Zhang, Sihua Liu, Yuhang Yang, Wanliang Sun, Dongdong Wang, Zhong Liu, Zheng Lu, Dengyong Zhang

Design and development of dual targeting CAR protein for the development of CAR T-cell therapy against KRAS mutated pancreatic ductal adenocarcinoma using computational approaches

Prasanna Srinivasan Ramalingam, T. Premkumar, Vino Sundararajan, Md Sadique Hussain, Sivakumar Arumugam

The prognostic significance of twist in pancreatic cancer and its role in cancer promotion through the regulation of the immune microenvironment and EMT mechanisms

Qing Li, Yu Liu, Renhou Zhi, Yinquan Wang

Correction: Accuracy and influencing factors of Type B2 vessels in predicting the invasion depth of superficial esophageal squamous cell carcinoma under narrow-band imaging magnifying endoscopy

Xu Lin, Xiaolu Lin, Wei Liang, Wangyin Deng, Wenming Liu

  • Open Access
  • Research

Glucose deprivation impairs hypoxia-inducible factor-1α synthesis

Mia Hubert, Sarah Stuart, Michael Ohh

The role of molecular subtypes and immune infiltration characteristics based on disulfidptosis-related genes in ovarian cancer

Ruanruan Yang, Yating Wang, Zhifu Wei, Zhanpeng Huang, Xiaoshan Hong, Yu Lin

Solute carrier family 4 member 4 (SLC4A4) is associated with cell proliferation, migration and immune cell infiltration in colon cancer

Chengqing Yu, Haoran Li, Chen Zhang, Yuchen Tang, Yujie Huang, Haodong Lu, Kanghui Jin, Jian Zhou, Jian Yang

The efficacy and safety of anlotinib combined with chemotherapy in treatment of advanced soft tissue sarcoma

Ying Ni, Yabing Dong, Aijun Jiang, Qun Zhang, Zhantong Wang, Hui Liang, Wei Zhang

IGSF1: a biomarker for predicting prognosis, immunotherapy response, and drug candidates in COVID-19 combined hepatocellular carcinoma

Yuanhui Guo, Baixuan Shen, Chaoxuan Lou, Li Wang, Ying Li

Construction of machine learning models of lipid metabolism-related long non-coding RNA in lung adenocarcinoma is associated with microenvironmental heterogeneity and immunotherapy

Jiali Xiong, Kailan Xiao, Huiyang He, Yuqiu Tian

CXCL8 may serve as a potential biomarker for predicting the prognosis and immune response in cervical cancer

Yi Yin, Yong Li, Yaoyang Zhang, Qiucheng Jia, Huiming Tang, Jiming Chen, Rui Ji

Unveiling the significance of cancer-testis antigens and their implications for immunotherapy in glioma

Shenghua Zhuo, Shuo Yang, Shenbo Chen, Yueju Ding, Honglei Cheng, Liangwang Yang, Kai Wang, Kun Yang

HOXB8 mediates resistance to cetuximab in colorectal cancer cells through activation of the STAT3 pathway

Yunan Liang, Han Lin, Zongsheng Jiang, Qi Zhao, Ri Cui, Shaotang Li

TMEM173 is a biomarker of predicting prognosis, immune responses and therapeutic effect in human lung adenocarcinoma

Pingting Zhou, Pengru Wang, Bo Li

Revisiting the diagnostic performance of exosomes: harnessing the feasibility of combinatorial exosomal miRNA profiles for colorectal cancer diagnosis

Jin Sung Park, Jin Ah Choi, Da Han Hyun, Chorok Byeon, Sang Gyu Kwak, Jun Seok Park, Seonki Hong

LINC00342 regulates the PI3K-AKT signaling pathway via the miR-149-5p/FGF11 axis and affects the progression of oral cancer

Yimiao Chen, Yanchun Wang, Wenbo Zhang

ATF4/NUPR1 axis promotes cancer cell survival and mediates immunosuppression in clear cell renal cell carcinoma

Yongliang Lu, Weihao Chen, Yundong Xuan, Xiubin Li, Shengpan Wu, Hanfeng Wang, Tao Guo, Chenfeng Wang, Shuo Tian, Huaikang Li, Dong Lai, Wenlei Zhao, Xing Huang, Xupeng Zhao, Baojun Wang, Xu Zhang, Hongzhao Li, Yan Huang, Xin Ma

The inhibitory efficacy of Ginsenoside Rg3 on proliferation and migration of colonic carcinoma cells through the JAK3/STAT5 signaling pathway

Xiumei Sun, Han Bi, Feng Gao, Xiaoyu Zhao, Xinyu Feng, Qifu Bo, Jin Liu, Wenhao Wang

Decoding core genes and intercellular communication in osteosarcoma: bioinformatic investigation and immune cell profiling for diagnostic and therapeutic insights

Kuan Rong, Haoming Kuang, Liang Ou, Rui Fang, Jianjun Kuang, Hui Yang

Identification and validation of CCN family genes to predict the prognosis in gastric cancer

Huanting Chen, Xiaomin Zhang, Zhe Zhang, Guoqiang Li, Xin Li, Siran Yang, Yajie Liu, Mengqi Yang

Preparation of transferrin-modified IR820-loaded liposomes and its effect on photodynamic therapy of breast cancer

Zhang Di, Zhang Shuhe, Shan Baoding, Zhao Yihan, Jin Guangming

Skimmed milk intake reduces the risk of ER− breast cancer: a Mendelian randomization analysis

Yingdan Huang, Wangjin Zhang, Jinghui Chen, Sihua Qiu, Chang Xue, Huijing Wu

The causal relationship between anti-CD20 antibodies and endometrial cancer: a Mendelian randomization study

Jinqiu Su, Zhuang Li, Jianli Wang, Nairong Liu, Liyi Bao, Jiayuan Du, Yan Li, Yaojie Yu, He Wang

Mechanism of CXCL8 regulation of methionine metabolism to promote angiogenesis in gliomas

Jie Chang, Yi Pan, Fengfeng Jiang, Wenxia Xu, Yue Wang, Lude Wang, Bin Hu

  • Open Access
  • Review

Unraveling the role of heavy metals xenobiotics in cancer: a critical review

Sourav Pal, Sayed Mohammed Firdous

  • Open Access
  • Research

Unveiling the Immune effects of AHR in tumors: a decade of insights from bibliometric analysis (2010–2023)

Anni Xie, Ting Wang, Wenjing Shi, Fang He, Xin Sun, Ping Li

Identifying causal relationships between 35 blood and urine biomarkers and urologic cancers: MR-meta combined with Bayesian colocalization Mendelian randomization analysis

Wenxin An, Chengyi Zhao, Yaru Wang, Yinghui Zhang, Zhi Qiao

The diagnosis and oncological outcomes of obturator and internal iliac lymph node metastasis in middle–low rectal cancer: results of a multicenter Lateral Node Collaborative Group study in China

Fei Huang, Ran Wei, Sicheng Zhou, Shiwen Mei, Tixian Xiao, Wei Xing, Qian Liu

Efficacy and safety of systemic treatment for progressive and refractory desmoid tumor: a systematic review and Bayesian network meta-analysis

Junyong Ou, Dandan Su, Yunhe Guan, Liyuan Ge, Shaohui Deng, Ye Yan, Yichang Hao, Min Lu, Shudong Zhang, Ruiyang Xie

HOXC12 promotes the invasion and migration of gastric cancer cells by upregulating SALL4 and activating Wnt/β-catenin signaling pathway

Jun Zhang, Nengbin Hou, Dewang Rao, Qian Chen, Zhongliang Ning, Ming Lu

Development and validation of a risk predictive nomogram for colon cancer-specific mortality: a competing risk model based on the SEER database

Wei Li, Yiting Liu

Prognosis and immunotherapy significances of a cancer-associated fibroblasts-related gene signature in bladder urothelial carcinoma

Xiaobin Chen, Yugen Li, Jing Huang, Qiang Zhang, Chunlin Tan, Yang Liu, Zhongbo Du

LINC02466 promotes the progression of hepatocellular carcinoma through the mTOR pathway

Shiqian Liu, Zhipeng Quan, Jiaming Liang, Fuqiang Wang, Hao Yan, Zhenran Wang, Bo Tang, Xuebin Qin

  • Open Access
  • Research

HPRT1: a preliminary investigation on its involvement in nasopharyngeal carcinoma

An Chen, Guifang Wang, Deli Wang, Ruyang Liu

Individualised prediction of chemotherapy benefit in early-onset colorectal cancer

Jian Li, De Ming Tong, Peng Lv, Peng Xu, Cheng Zhang

NEK2 is a potential pan-cancer biomarker and immunotherapy target

Lanyue Zhang, Yang Li, Juexiao Deng, Wenxin Liao, Tingting Liu, Fujin Shen

  • Open Access
  • Analysis

SPINK5 is a key regulator of eosinophil extracellular traps in head and neck squamous cell carcinoma

Chifeng Zhao, Haoran Zhu, Yu Tian, Yuewen Sun, Zhenxing Zhang

A bidirectional Mendelian randomization analysis of the causal relationship between inflammatory bowel disease and breast cancer based on estrogen receptor status

Xindi Ma, Shang Wu, Xiangmei Zhang, Kaiye Du, Chenhui Yang, Sinuo Gao, Yunjiang Liu

The association of preoperative serum free fatty acid levels with survival in breast cancer patients

Liuran Li, Liang Jin, Lili You, Qiang Liu, Li Yan

  • Open Access
  • Review

Advances and prospects in tumor infiltrating lymphocyte therapy

Xu Qiu, Shengjun Li, Tianyu Fan, Yue Zhang, Bin Wang, Bei Zhang, Mingzhe Zhang, Li Zhang

Construction of a novel mitochondrial oxidative stress-related genes prognostic system and molecular subtype characterization for breast cancer

Ying Liu, Yang Li, Yanzheng Zhu, Min Wang, Zheyao Luan

The potential clinical value of platelet aggregation in colorectal tumor progression

Yuyu Chen, Guanghua Liu, Jialong Yuan, Ju Zuo, Huan Liu, Hao Liu

POLQ knockdown inhibits proliferation, migration, and invasion by inducing cell cycle arrest in colorectal cancer

Qing Yao, Shuyang Gao, Qiannan Sun, Liuhua Wang, Jun Ren, Daorong Wang

Hsa_circ_0000423 promotes colorectal cancer EMT and immune escape by competitive adsorption of miR-369-3p mediating CCND1 expression

TianFu Huang, KaiHai Jiang, LinTao Li, GuangSheng Li, YuSheng Cao, XuSen Huang

  • Open Access
  • Analysis

Development of a novel disulfidptosis-correlated m6A/m1A/m5C/m7G gene signature to predict prognosis and therapeutic response for lung adenocarcinoma patients by integrated machine-learning

Bilin Xu, Liangyu Zhang, Lijie Lin, Yanfeng Lin, Fancai Lai

  • Open Access
  • Research

Asparaginase and isoaspartyl peptidase 1 RNA interference suppresses the growth of nasopharyngeal carcinoma cells

Bo Feng, Yingying Pei, Weiwei Zhang, Qi Zheng, Yan Zhou

  • Open Access
  • Analysis

The protective role of vitamin d in nasopharyngeal carcinoma: insights from Mendelian randomization and meta-analysis

Ting Yi, Shaoxiong Lin

A novel double fusion of EML4-ALK and PLEKHA7-ALK contribute to rapid progression of lung adenocarcinoma: a case report and literature review

Zhongzhao Wang, Yang Luo, Heng Gong, Yang Chen, Hao Tang

  • Open Access
  • Research

Expression of the lncRNA TPT1-AS1 in lung squamous cell carcinoma and its prognostic value

Lixin Yu, Zhenkui Zhang, Zhijian Wang, Fenghua Sun

Enhancing antitumor activity of herceptin in HER2-positive breast cancer cells: a novel DNMT-1 inhibitor approach

Li-li Ren, Yan-ru Song, Zhen-chuan Song, Hua Yang, Qian Zhang, Meng-meng Ji, Na Xiao, Ming Wen, Ji-hai Wang

  • Open Access
  • Review

Polymer-drug conjugates: revolutionizing nanotheranostic agents for diagnosis and therapy

Ashish Kumar Parashar, Gaurav Kant Saraogi, Pushpendra Kumar Jain, Balakdas Kurmi, Vivek Shrivastava, Vandana Arora

Identification of a coagulation-related gene signature for predicting prognosis in recurrent glioma

Ming Cao, Wenwen Zhang, Jie Chen, Yuchen Zhang

Circ_0001741 exerts as a tumor promoter in ovarian cancer through the regulation of miR-491-5p/PRSS8 axis

Ding Wang, Sumin Zhang, Qiaoling Wang, Pengrong Li, Yunxia Liu

Prognostic significance and identification of m6A regulator genes and hub genes associated with m6A in breast cancer

Longjie Xia, Runchun Huang, Yingxiong Huang, Huixian Huang, Yunxiang Luo, Yixuan Qin, Shaoliang Zhu, Fanbiao Kong, Weiwei Miao

Long-term outcomes and prognostic factors of short-course radiotherapy (SCRT) in rectal cancer: a monocentric retrospective study

Giuseppe Facondo, Federico Belotti, Margherita Rotondi, Gianluca Vullo, Silvia Fiorelli, Stefano Mossa, Vitaliana De Sanctis, Mattia Falchetto Osti

Late side effects of testicular cancer and treatment: a comprehensive review

M. Raheel Khan, Patrice Kearney Sheehan, Ashley Bazin, Christine Leonard, Umair Aleem, Lynda Corrigan, Ray McDermott

Enrichment of cancer stem cell subpopulation alters the glycogene expression profile of colorectal cancer cells

Jéssica de Andrade-da-Costa, Michelle de-Souza-Ferreira, Nathália Campos dos Santos Touça, Annie Cristhine Moraes Sousa-Squiavinato, Sheila Coelho Soares-Lima, José Andrés Morgado-Díaz, Julio Cesar Madureira de-Freitas-Junior

Circ_0001068 accelerates the development of ovarian cancer by promoting FXYD5 expression through inhibiting mir-149-5p activity

Zhengqian Mou, Lingyan Ge, Saiya Ye, Zhiyong Gong

Comprehensive analysis of single-cell and bulk RNA sequencing reveals postoperative progression markers for non-muscle invasive bladder cancer and predicts responses to immunotherapy

Zhiliang Xiao, Xin Liu, Yuan Wang, Sicong Jiang, Yan Feng

Development and validation of survival nomograms for patients with anaplastic thyroid carcinoma: a SEER program-based study

Xinming Chen, Pingwu Zhao, Yunsheng He, Kun Huang, Pan Zhao, Fengwan Liao, Yang Liu

Triglyceride-glucose index predicts postoperative overall survival in hepatocellular carcinoma: a retrospective cohort study

Gao-Min Liu, Wen-Biao Zhu, Ji-Wei Xu

Understanding serine and glycine metabolism in cancer: a path towards precision medicine to improve patient’s outcomes

Anaís Sánchez-Castillo, Kim R. Kampen

Developing hypoxia and lactate metabolism-related molecular subtypes and prognostic signature for clear cell renal cell carcinoma through integrating machine learning

Jinhui Liu, Tianliu Yang, Jiayuan Liu, Xianghui Hao, Yuhang Guo, Sheng Luo, Benzheng Zhou

Pan-cancer analysis of STAT3 indicates its potential prognostic value and correlation with immune cell infiltration in prostate cancer

Zhouting Tuo, Hesong Zhang, Ke He, Zhiwei Jiang, Chao Jiang, Xin Chen, Haichao Yuan

Correlation between glucose metabolism and body mass index in tumor lesions of patients with lung cancer

Zhengqin Zhao, Xiaona Wang, Dong Wang, Jiahui Zhang, Hongjie Yang

Radiotherapy in patients with brain metastases with and without concomitant immunotherapy: comparison of patient outcome and neurotoxicity

Natalie Elyan, Philipp Schwenkenbecher, Lea Grote-Levi, Jan-Niklas Becker, Roland Merten, Hans Christiansen, Thomas Skripuletz, Diana Steinmann, Nora Möhn

  • Open Access
  • Analysis

Survival prediction in patients with head and neck squamous cell carcinoma and novel mechanistic insights of S100A8/A9

Yihong Hu, Minhui He, Yucheng Han, Lu Zeng, Ziwei Ma, Xianqiong Zou

  • Open Access
  • Review

The potential of kaempferol in digestive system tumors: recent advances and mechanistic insights

Xunxing Hao, Meng Ding, Chenyu Chi, Xiaodong Xu, Xiaoyu Zhang, Mingzhe Hu

Network pharmacology and in vitro experiments to investigate the anti-gastric cancer effects of paeoniflorin through the RAS/MAPK signaling pathway

Yating Yang, Ling Yuan, Yuhua Du, Mengyi Ye, Doudou Lu, Shicong Huang, Jianjun Zhao, Joanna Japhet Tibenda, Fandi Meng, Yi Nan

Succinylation modification-mediated upregulation of Sp1 promotes hepatocellular carcinoma cell proliferation

Yehong Han, Xueqin Deng, Haixia Chen, Jie Chen, Wei Xu, Lanqin Liu

Immune-oncology targets and therapeutic response of cell pyroptosis-related genes with prognostic implications in neuroblastoma

Xingyu Liu, Zhongya Xu, Hanjun Yin, Xu Zhao, Jinjiang Duan, Kai Zhou, Qiyang Shen

MicroRNA-mediated autophagy and drug resistance in cancer: mechanisms and therapeutic strategies

Jinxing Wei, Xianghui Wang, Duo Yu, Yanyang Tu, Yaoyu Yu

Correlation between thyroid dysfunction and efficacy of immune checkpoint inhibitors in patients with advanced solid tumors

Cheng Zhao

Single-cell data revealed the regulatory mechanism of TNK cell heterogeneity in liver metastasis from gastric cancer

Jun Gao, Yujuan Liu, Lu Tao, Peng Zeng, Guiying Ye, Ying Zheng, Nai Zhang

  • Open Access
  • Research

Research trends, hotspots and future directions of tertiary lymphoid structures in cancer: a comprehensive informatics analysis and visualization study

Chengdong Yu, Jiawei Xu, Siyi Xu, Lei Tang, Qinyuan Han, Zhengkui Sun

Single-cell expression and immune infiltration analysis of polyamine metabolism in breast cancer

Xiliang Zhang, Hanjie Guo, Xiaolong Li, Wei Tao, Xiaoqing Ma, Yuxing Zhang, Weidong Xiao

SLITRK2 as a prognostic and immunological biomarker in gastric cancer

Huiqiong Zhu, Hailin Xiong, Xuli Guo, Haojie Liao, Shuyi Zhang

  • Open Access
  • Analysis

Construction of a novel lipid drop-mitochondria-associated genetic profile for predicting the survival and prognosis of lung adenocarcinoma

Ruijuan Cai, Hongsheng Lin, Qianwen Cheng, Qiyuan Mao, Chuchu Zhang, Ying Tan

Integrated single-cell analysis reveals heterogeneity and therapeutic insights in osteosarcoma

Dongan He, Xiaoqian Che, Haiming Zhang, Jiandong Guo, Lei Cai, Jian Li, Jinxi Zhang, Xin Jin, Jianfeng Wang

  • Open Access
  • Research

Circ_0124346 facilitates cell proliferation of pancreatic adenocarcinoma cells by regulating lipid metabolism via miR-223-3p/ACSL3 axis

Meng-lu Shu, Wan-ting Yang, Hui-min Li, Cui-juan Qian, Xiao-sheng Teng, Jun Yao

TMSB4X is a regulator of inflammation-associated ferroptosis, and promotes the proliferation, migration and invasion of hepatocellular carcinoma cells

Linlin Tang, Yangli Jin, Jinxu Wang, Xiuyan Lu, Mengque Xu, Mingwei Xiang

Importance of LINC00852/miR-145-5p in breast cancer: a bioinformatics and experimental study

Abbas Shakoori, Asghar Hosseinzadeh, Nahid Nafisi, Ramesh Omranipour, Leyla Sahebi, Nazanin Hosseinkhan, Mohsen Ahmadi, Soudeh Ghafouri-Fard, Maryam Abtin

ATP6V1C1, associated with the tumor microenvironment and mTORC1 signaling pathway, is a potential diagnostic, prognostic, and therapeutic biomarker for hepatocellular carcinoma

Yuhao Pan, Hao Chen, Chenhui Lv, Wei He, Yongpeng Xu, Qijia Xuan

Multi-omics analysis reveals the role of the autophagy-related gene AGT in chemotherapy resistance in colorectal cancer and the therapeutic potential of its inhibitors

Wenjiao Cai, Tao Xiang, Xiaoli Liu, Chong Fu

Causal relationship between immune cells and acute myeloid leukemia: a two-sample Mendelian randomization study

Fanhua Yu, Hao Jiang, Yena Gu

SLC1A3 is a novel prognostic biomarker associated with immunity and EMT in hepatocellular carcinoma

Renhou Zhi, Fan Fan

Flavokawain A suppresses the malignant progression of neuroblastoma in vitro depending on inactivation of ERK/VEGF/MMPs signaling pathway

Mengyao Dong, Gaiqin Li, Geng Geng, Ming Ming, Yongtao Xu

Aberrant expression of MRAS and HEG1 as the biomarkers for osimertinib resistance in LUAD

Mingxin Liu, Bo Tang, Run Xiang, Peihong Hu, Chuan Xu, Lanlin Hu, Qiang Li

Targeting ferroptosis reveals a new strategy for breast cancer treatment: a bibliometric study

Junlin Liu, Rong Tang, Jie Zheng, Ke Luo

Identification and validation of a novel prognostic signature and key genes related to development of anaplastic thyroid carcinoma

Kai Qian, Qiang Feng, Jia-Rui Wang, Jia-De Zhu, Ping Wang, Yu Guo, Tao Zhou, Qian-Wei Zhu, Liao Cai, Zheng Zhang, Gong-Hao He

GLN2 as a key biomarker and therapeutic target: evidence from a comprehensive pan-cancer study using molecular, functional, and bioinformatic analyses

Shuang Gao, Lei Zhang, Guoping Sun

KLF4 promotes cisplatin resistance by activating mTORC1 signaling in ovarian cancer

Wanzhen Zhou, Huixian Huang, Yincheng Teng, Rong Hua, Yan Hu, Xiao Li

Unraveling the role of gut microbiota and immune cells in thyroid cancer and tumor drug resistance

Jiaqin Deng, Yihua Gu, Ming Yu, Yeqian Lai, Lihong Qiu

Pyroptosis-related lncRNAs are potential biomarkers for predicting prognoses and immune landscapes in patients with gastric adenocarcinoma

Haidu Hong, Yuancheng Huang, Zehong Yang, Xiaotao Jiang, Hong Liu

  • Open Access
  • Research

Systematic regulation of immune checkpoint molecules by redox regulators CNC-bZIP transcription factors

Haoming Ning, Qiufang Yang, Yonggang Ren, Lu Qiu

Changes in the tumor microenvironment in recurrent head and neck squamous cell carcinoma and its implication on efficacy of immune checkpoint inhibitors

Dong Hyun Kim, Mingu Kang, Gahee Park, Mohammad Mostafavi, Yoojoo Lim, Chan-Young Ock, Jiwon Koh, Yoon Kyung Jeon, Kyeong Cheon Jung, Soon-Hyun Ahn, Eun-Jae Chung, Seong-Keun Kwon, Bhumsuk Keam

  • Open Access
  • Research

Prognostic analysis of early-onset and late-onset nasopharyngeal carcinoma: a retrospective study

Pian Li, Zhen Meng, Dong Yang, Tianyu Wu, Yating Qin, Xinghua Chen, Yaya Wang, Chuangjie Cao, Min Kang

  • Open Access
  • Review

Anticancer effect of Moringa oleifera in oral squamous cell carcinoma: a systematic review

Chandini Rajkumar, Saranya Ramsridhar, Vishnu Priya Veeraraghavan, Arul Prakash Francis, M. Purushotham, Uma Mageshwari

Assessing the predictive role of platelet-lymphocyte ratio in EGFR-mutated non-small cell lung cancer patients treated with tyrosine kinase inhibitors: an analysis across TKI generations

Ryan Cooper, Dhruv Ramaswami, Jacob S. Thomas, Jorge J. Nieva, Robert Hsu

Roles of cathepsin S expression levels on the prognosis and tumour microenvironment in clear cell renal cell carcinoma

Xiang Wang, Bei Feng, Hai-Ying Guo, Fei-Fei Yao, Hui-Nan Song, Xi-Yue Wang, Xiao-Chen Sun, Kai Wang, Yu-Chen Ge, Rui Cui

A rare case of pediatric T-cell acute lymphoblastic leukemia with myeloid mimicry

Wenpeng Ni, Ji Liu, Kunyi Deng, Zhouyu Zeng, Qingzhu Kong, Xiaoling Weng

Awareness of breast cancer and perceived barriers to breast screening methods: a community based cross-sectional study among women in Yemen

Gamil Othman, Faisal Ali, Maria Mudathir, Heba Almoliky, Maria Al-qahtani, Nora Alezzi, Nosibah Ameen, Doa’a Anwar Ibrahim, Mohammed Mohammed Battah, Mohamed Izham Mohamed Ibrahim

LncRNAs SOX2-OT and NEAT1 act as a potential biomarker for esophageal squamous cell carcinoma

Rajiv Ranjan Kumar, Adrija Mohanta, Manjit Kaur Rana, Vivek Uttam, Hardeep Singh Tuli, Aklank Jain

  • Open Access
  • Research

Systematic pan-cancer analysis of the prognostic value of MECOM in human cancer

Yingqiang Lu, Jing Quan, Feng Liu, Banggao Huang

Detection of circulating tumor cells in peripheral blood of patients with tongue squamous cell carcinoma and its relationship with clinical features and prognosis: a retrospective study

Ningbo Geng, Weiyi Lin, Dandan Zhang, Wei Cao, Chongjin Feng, Shan Chen

Single-cell analysis uncovers liver susceptibility to pancreatic cancer metastasis via myeloid cell characterization

Aizier Ainiwaer, Zhenwei Qian, Jianxun Wang, Qi Zhao, Yinying Lu

Exploring new mechanisms in cancer molecular pathways and pathogenic cell transformation: PIP4K2A as a prognostic marker and therapeutic target in cutaneous malignant melanoma

Wen-fei Luo, Ding-ming Song, Tong Shen, Yi-bo He, Hong-yang Du, Ming-jue Si, Lu-Wei Fang

Tumor analysis of BRCA carriers reveals genomic similarities although separated by time

Tal Falick Michaeli, Avital Granit Mizrahi, Batia Azria, Ofra Maymon, Shai Rosenberg, Jonathan Monin, Esther Braitbart Cohen, Myriam Maoz, Luna Kadiuri, Hovav Nechushtan, Amichay Meyrowitz, Tamar Peretz

  • Open Access
  • Analysis

Transcriptomic, mutational and structural bioinformatics approaches to explore the therapeutic role of FAP in predominant cancer types

Gayathri Ashok, Abdullah F. AlAsmari, Fawaz AlAsmari, Paul Livingstone, Anand Anbarasu, Sudha Ramaiah

Hsa_circ_0072732 enhances sunitinib resistance of renal cell carcinoma by inhibiting ferroptosis

Xiaorui Tian, Jun Liu, Cheng Yi, Xiangyun You, Chunli Yuan

Decreased mitochondrial transcription factor A and mitochondrial DNA copy number promote cyclin-dependent kinase inhibitor 1A expression and reduce tumorigenic properties of colorectal cancer cells

Jessika Buchwaldt, Tania Fritsch, Monika Hartmann, Hagen Roland Witzel, Michael Kloth, Wilfried Roth, Katrin E. Tagscherer, Nils Hartmann

Predicting survival in bladder cancer with a novel apoptotic gene-related prognostic model

Ding-ming Song, Kun Feng, Wen-fei Luo, Dong-shan Lv, Li-po Zhou, Yi-bo He, Yanyang Jin

Nomogram for predicting cervical lymph node metastasis of papillary thyroid carcinoma using deep learning-based super-resolution ultrasound image

Xia Li, Yu Zhao, Wenhui Chen, Xu Huang, Yan Ding, Shuangyi Cao, Chujun Wang, Chunquan Zhang

  • Open Access
  • Research

FCGBP functions as a tumor suppressor gene in head and neck squamous cell carcinoma

Lijuan Zeng, Jun Zeng, Jianfeng He, Yongqi Li, Chengwei Li, Zhiyan Lin, Guangwei Chen, Huilin Wu, Libin Zhou

Engrailed 2 facilitates progression of triple-negative and HER2-enriched breast cancer by binding to enhancer region of Tenascin-C

Dandan Chen, Rongping Yin

BIRC5 knockdown ameliorates hepatocellular carcinoma progression via regulating PPARγ pathway and cuproptosis

Yanxing Mai, Zhuocheng Ji, Yujing Tan, Lei Feng, Jiasheng Qin

A comprehensive analysis of gene expression and the immune landscape in gastric cancer through single-cell and multi-omics approaches

Tao Peng

Survival outcomes fifteen years after minimally invasive esophagectomy

Amira Orabi, Gauri Chillarge, Davide Di Mauro, Dharmarajah Veeramootoo, Ikechukwu Njere, Antonio Manzelli, Shahjehan Wajed

Pralatrexate represses the resistance of HCC cells to molecular targeted agents via the miRNA-34a/Notch pathway

Yang Jin, Qiming Liu, Baisheng Sun, Xiaokang Li, Jiahao Wu, Zhiyuan Lin, Yan Ma, Haijiang Jia

Genetic insights into blood protein correlations with colorectal cancer: a Mendelian randomization study

Wenjing Xu, Wei Li, Yaqiang Li, Dayu Kuai, Wei Sun, Xian Liu, Baohong Xu

Anti-tumor activity of butorphanol in colorectal cancer via targeting SIGMAR1

Xueqi Hou, Longfei Qu, Yong Xu, Jie Liu, Jianlian Guo

Safety and efficacy of generic nab-paclitaxel-based therapy in Chinese patients with malignant tumors in a real-world setting: a multicenter prospective observational study

Fei He, Yancai Sun, Wenzhou Zhang, Qiongshi Wu, Donghang Xu, Zaixian Bai, Zhiying Hao, Weiyi Feng, Kanghuai Zhang, Jiang Liu, Mei Dong, Guangxuan Liu, Guohui Li

Advances in irreversible electroporation for prostate cancer

Xinyu Liu, Hao Wang, Zilin Zhao, Qikai Zhong, Xinlei Wang, Xing Liu, Junzhi Chen, Conghui Han, Zhenduo Shi, Qing Liang

Role of early growth response-1 as a tumor suppressor in oral squamous cell carcinoma

Yudai Shimojukkoku, Phuong Thao Nguyen, Kiyohide Ishihata, Takayuki Ishida, Yuka Kajiya, Yasunobu Oku, Koshiro Kawaguchi, Takahiro Tsuchiyama, Hideto Saijo, Kaori Shima, Tomonori Sasahira

  • Open Access
  • Analysis

Identification of gasdermin B function in the progression of renal clear cell carcinoma by a pan-cancer analysis

Xiangyuan Tan, Zhanzhan Li, Yanyan Li

TLN1: an oncogene associated with tumorigenesis and progression

Sixin Li, Anjie Chen, Jiandong Gui, Hangsheng Zhou, Lijie Zhu, Yuanyuan Mi

  • Open Access
  • Research

Development of a novel centrosome-related risk signature to predict prognosis and treatment response in lung adenocarcinoma

Ziqiang Wang, Chao Zuo, Jiaojiao Fei, Huili Chen, Luyao Wang, Yiluo Xie, Jing Zhang, Shengping Min, Xiaojing Wang, Chaoqun Lian

Prognostic alternative splicing and multi-omics characteristics reveal FTCD is a potential target of hepatocellular carcinoma

Yanli Zhang, Wenxing Li, Mengyi Sun, Lisheng Zhang

Epstein–Barr Virus and gastric carcinoma pathogenesis with emphasis on underlying epigenetic mechanisms

Fatemeh Estaji, Saeed Zibaee, Maryam Torabi, Sharareh Moghim

Improved lymph node detection in minimally invasive radical surgery for colorectal cancer using nanocarbon tracer

Bingkai Xie, Guihe Lin, Zhijian Wang, Dongbo Xu, Jianxun Chen, Shuangming Lin

Type 2 diabetes and colorectal cancer: genetic causality explored via Mendelian randomization

Qiuhong Ke, Yongbing Huang, Libin Cheng, Chaolin Lin, Linhua Zhao, Wulong Huang, Zhisheng Chen, Yimin Xu, Yipiao Huang, Lanlan Cai, Bin Lin, Rui Tang

Comprehensive characterization of neddylation related genes in cutaneous melanoma identified a novel prognostic signature for treatment outcomes, immune landscape

Min Zhang, Jian Liu, Fangxu Zhang, Qian Liang, Zhiqiang Guo

Novel signature of ferroptosis-related long non-coding RNA to predict lower-grade glioma overall survival

Shiji Wu, Wenxi Wu, Yaqi Zhong, Xingte Chen, Junxin Wu

Integrated analysis of disulfidptosis-related genes SLC7A11, SLC3A2, RPN1 and NCKAP1 across cancers

Zequn Zheng, Yongfei Song

Exon 1 methylation status of CDH13 is associated with decreased overall survival and distant metastasis in patients with postoperative colorectal cancer

PengCheng Xiang, PengJu Li, Xiaoqi Yuan, Xiuhao Zhao, Zitian Xiao, Bingguan Chen, Kenwen Liu, Evelyne Bischof, Junyi Han

New direction: identification of immunoinflammatory subtypes and potential therapeutic targets for cholangiocarcinoma

Zhixuan Chen, Honghu Song, Junrui Tang, Jiao Liu, Lina Xia

Identification of genetic and immune mechanisms linking preeclampsia and endometrial cancer: a prognostic model for survival and treatment response

Fei Teng, Guangjuan Fang, Jing Wang, Yongxiu Yang

The effect and mechanism of IL-37d on neutrophil recruitment in the early stage of tumor metastasis in the lungs

Yetong Guan, Chang Gao, Yan Guo, Meifang Wang, Lining Zhang

Recent advances on biogenesis, functions and therapeutic potential of long noncoding RNAs in T cell acute lymphoblastic leukemia

Parminder Kaur, Pankaj Sharma, Prateek Bhatia, Minu Singh

Ferroptosis-related lncRNA AL136084.3 is associated with NUPR1 in bladder cancer

Jing Zhou, Li Zhang, Hao Wu, Sheng-Lin Gao, Xiao-Ping Chen, Li-Feng Zhang, Cui-Ping Zhao, Bing-Bing Wei, Yu Bai

The immune cells causative role in lung cancer: Mendelian randomization study

Qianhui Zhou, Yanchao Liang, Xun Chen, Siwei Qi, Lanlan Wei

Evaluating KLHDC8A as a biomarker for glioma: impact on survival and proliferation through the Wnt/β-catenin pathway

Yu Tian, Xiaofei Hu, Xiaoling Wang, Youcai Huang, Junfeng Hao, Yu Guo, Chao Zhu, Yanyang Tu

Treatment of metastatic breast cancer by stereotactic body radiotherapy (SBRT) and stereotactic radiosurgery (SRS)

Xiaomin Li, Yu Sun, Liang Tang, Yan Li, Xiaoqin Yang

Investigating the biomarker value of circRNAs in the diagnosis of colorectal cancer: a systematic review

Tahereh Latifi-Pakdehi, Ali Khezrian, Amin Doosti-Irani, Saeid Afshar, Ali Mahdavinezhad

miR-328-3p suppresses hepatocellular carcinoma progression by regulating HMOX1 expression

Weixing Wang, Jun Li, Changjun Pan, Deguo Wang, Jian Dong

Current advances on the role of ferroptosis in tumor immune evasion

Changlin Gao, Haoran Zhang, Xianwei Wang

Deciphering the causal landscape: genetic insights into sporadic vestibular schwannoma risk factors through Mendelian Randomization

Yuyang Liu, Hui Feng, Hengchao Ma, Jing Li, Yang Yu, Hua Zhao, Xiaoguang Wang, Yun Li, Jun Zhang, Qi Liu

Multi-omics joint screening of biomarkers related to M2 macrophages in gastric cancer

Xilong Wang, Ying Zhang

  • Open Access
  • Research

The characteristics and functional significance of disulfidptosis-related genes in head and neck squamous cell carcinoma

Haiqian Zhu, Chifeng Zhao, Haoran Zhu, Xuhui Xu, Conglin Hu, Zhenxing Zhang

  • Open Access
  • Analysis

Investigating the role of KARS in lung adenocarcinoma via single-cell RNA sequencing

Huafang Hu, Yan Zhong, Guangbiao Li, Ru Deng, Jingfu Lin, Wenkun Wu, Yonghong Li

Identification and validation of cigarette smoking-related genes in predicting prostate cancer development through bioinformatic analysis and experiments

Duocheng Qian, Xin’an Wang, Tengfei Lv, Dujian Li, Xi Chen

Identification and construction of prognostic clusters and risk-prognosis model based on aging-immune related genes in bladder cancer

Nihao Cao, Fei Cheng, Jincai Zhou, Ning Liu

Unraveling molecular signatures and prognostic biomarkers in glioblastoma: a comprehensive study on treatment resistance and personalized strategies

Jinmin Xue, Jie Zhang, Jing Zhu

Development and validation of a prognostic risk score model for hepatocellular carcinoma in the Asian population based on immunogenic cell death-related genes

Zhengyang Feng, Yanjie Wang, Yong Liang, Xuhao Gu, Yinyin Yang, Yusong Zhang, Qiliang Peng

CMTM6 status predicts survival in head and neck squamous cell carcinoma and correlates with PD-L1 expression

Anne-Sophie Becker, Nicolas Wieder, Sarah Zonnur, Annette Zimpfer, Mareike Krause, Björn Schneider, Daniel Fabian Strüder, Ann-Sophie Burmeister, Andreas Erbersdobler, Christian Junghanss, Claudia Maletzki

Prognostic value of preoperative D-dimer to albumin ratio in patients with locally advanced rectal cancer after neoadjuvant chemoradiotherapy

Zhen Pan, Ye Wang, Shoufeng Li, Huajun Cai, Guoxian Guan

Single-cell RNA sequencing analysis reveals potential key prognostic markers in hepatocellular carcinoma

Heteng Cui, Wenyuan Yang

The impact of different treatments on thromboelastography and other conventional parameters in patients with colorectal cancer

Wenqin Ren, Hao Chen, Yujie Huang, Jiaqian Zuo, Xinyan Shu, Peng Shu

Identification of common core genes and pathways in childhood sepsis and cancer by bioinformatics analysis

Yi-Ran He, Ni Ding, Ming-Chen Han, Hong-Yu He, Li-Zhen Xuan, Zhun-Yong Gu, Ming Zhong, Min-Jie Ju

BUD23 promote the cell proliferation ability by affecting the PPAR signaling pathways: evidence from the online dataset and cell experiment

Tao Huang, Binbin Jiao, Zhenkai Luo, Xiaolei Zhang, Zengjun Wang

  • Open Access
  • Research

Computer-aided analysis reveals metallothionein-positive cancer-associated fibroblasts promote angiogenesis in gastric adenocarcinoma

Xiaolong Jin, Yu Tian, Haoran Zhu, Yuewen Sun, Zhenxing Zhang

Cell-permeated peptide P-T3H2 inhibits malignancy on hepatocellular carcinoma through stabilizing HNF4α protein

Si-Han Wu, Meng-Chao Xiao, Fang Liu, Huan-Yu Hong, Chen-Hong Ding, Xin Zhang, Wei-Fen Xie

The T cell-mediated tumor killing patterns revealed tumor heterogeneous and proposed treatment recommendation in ovary cancer

Xinglin Wen, Beining Yin, Li Lin, Long Liu, Siyuan Weng, Hui Xu, Yuyuan Zhang, Jinhai Deng, Ruiying Liao, Cungeng Fan

  • Open Access
  • Research

Role of lncRNA TPRG1-AS1 in the development of cervical squamous cell carcinoma and its prognostic value

Yang Fan, Lan Ye, Shuyu Wang, Junwei Wang, Ke Wang, Ying Li

A rare case of huge intracranial yolk sac tumor presenting as an orbital mass in an infant: case report and literature review

Gashaw Arega, Melaku Moges, Abinzer Tirist, Tseganesh Mekonnen Hailemariam, Isa Salo Abdo, Fadil Nuredin Abrar, Ilili Amin Aliye

Revolutionizing cancer treatment: the rise of personalized immunotherapies

Amna Fayyaz, Aleena Haqqi, Rashid Khan, Muhammad Irfan, Khushbukhat Khan, Željko Reiner, Javad Sharifi-Rad, Daniela Calina

  • Open Access
  • NSCLC
  • Research

Comparison of targeted next generation sequencing assays in non-small cell lung cancer patients

Ieva Drejeriene, Jurate Gruode, Saulius Cicenas, Charalambos Loizides, Alexia Eliades, Achilleas Achilleos, Elena Kypri, Kyriakos Tsangaras, Marios Ioannides, George Koumbaris, Diana Stanciute, Arnoldas Krasauskas, Philippos C. Patsalis

Serum hemoglobin and albumin levels serve as prognostic predictors after adrenal metastasectomy

Nan Ma, Xiaobo He, Qiwei Nei, Zhenhua Liu, Xianda Chen, Hui Chang, Kai Yao, Shengjie Guo

Development and validation of disulfidptosis-related genes signature for patients with glioma

Jia Wang, Junchi Luo, Sha Yang, Yongbing Deng, Peng Chen, Ying Tan, Yang Liu

Research progress on the anti-tumor effects of euphorbia humifusa

Xiaoxue Zhao, Chengcheng Zhang, Xinle Qian, Jia Zhang, Guoying Wang, Zhongqi Wang

Concordance of HER2 status between primary tumor and circulating tumor cells in breast cancer

Peipei Xie, Xiaoli Zhang, Tianyi Liu, Yuchun Song, Qi Zhang, Duo Wan, Shijia Wang, Shulian Wang, Wen Zhang

Transcriptomic analysis reveals potential crosstalk genes and immune relationship between triple-negative breast cancer and depression

Zhili Zhuo, Wenping Lu, Ling Zhang, Dongni Zhang, Yongjia Cui, Xiaoqing Wu, Heting Mei, Lei Chang, Qingya Song

Letter to the Editor: Spatial proximity of tumor–immune interactions predicts patient outcome in hepatocellular carcinoma

Gaoyao Peng, Jiangfa Li, Xinchou Wang

HSP and CD279 gene expression as candidate biomarkers in symptomatic LGLL patients

Giovanna Talarico, Andrea Franceschini, Alessandro Raveane, Paolo Falvo, Saveria Mazzara, Federica Melle, Giovanna Motta, Stefania Orecchioni, Annamaria Tenore, Giuliana Gregato, Claudia Poletti, Roberto Chiarle, Stefano Pileri, Patrizia Mancuso, Francesco Bertolini

The landscape in telomere related gene prognostic signature for survival and medication treatment effectiveness prediction in hepatocellular carcinoma

Kai Zhou, Xingyu Liu, Mingda Wang, Jinjiang Duan, Xu Zhao, Hanjun Yin

Circular RNA NINL accelerates the malignant progression of cervical cancer

ChengCheng Cao, HaiFeng Zhang, Ting Zhang, CuiCui Nie

  • Open Access
  • Review

Circadian rhythms and cancer: implications for timing in therapy

Mohamed El-Tanani, Syed Arman Rabbani, Areeg Anwer Ali, Ibrahim Ghaleb Ali Alfaouri, Hamdi Al Nsairat, Israa Hamid Al-Ani, Alaa A. Aljabali, Manfredi Rizzo, Dimitrios Patoulias, Mohammad Ahmed Khan, Suhel Parvez, Yahia El-Tanani

Network pharmacology and anticancer mechanism study of Dendrobium nobile dendrobine in the treatment of colorectal cancer

Pei Luo, Can Huang, Jun Guo, Xin Yao, Chao Pan, Aijin Bao, Fei Li, Ying-ying Li

Unraveling the causal relationship and potential mechanisms between osteoarthritis and breast cancer: insights from mendelian randomization and bioinformatics analysis