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Published in: international journal of stomatology & occlusion medicine 4/2015

01-12-2015 | review

Diagnostic efficacy of saliva in oral and systemic health

Authors: Tanya Khaitan, Arpita Kabiraj, Preeti Tomar Bhattacharya, Uday Ginjupally, Harshvardhan Jha

Published in: international journal of stomatology & occlusion medicine | Issue 4/2015

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Abstract

Saliva has the potential to become a first-line diagnostic sample of choice owing to the advancements in detection technologies coupled with combinations of biomolecules with clinical relevance. Saliva is increasingly being used as an investigational aid in the diagnosis of oral and systemic diseases. It is a complex fluid containing a variety of enzymes, hormones, antibodies, antimicrobial constituents, and growth factors. Thus, saliva is functionally equivalent to serum, but its low concentration compared with serum levels in the blood may prevent salivary diagnostics from being clinically practical. However, with the development of new and highly sensitive techniques the low concentration of analytes in saliva is no longer a limitation. Evaluation of the secretions from individual salivary glands is useful for the detection of gland-specific pathology and whole saliva is used for the evaluation of systemic disorders. This review article highlights the diagnostic applications of saliva for systemic diseases and for monitoring of general health.
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Metadata
Title
Diagnostic efficacy of saliva in oral and systemic health
Authors
Tanya Khaitan
Arpita Kabiraj
Preeti Tomar Bhattacharya
Uday Ginjupally
Harshvardhan Jha
Publication date
01-12-2015
Publisher
Springer Vienna
Published in
international journal of stomatology & occlusion medicine / Issue 4/2015
Print ISSN: 1867-2221
Electronic ISSN: 1867-223X
DOI
https://doi.org/10.1007/s12548-015-0133-7

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