Is amylin the missing piece of the puzzle when it comes to precision diabetology? Explore amylin’s diverse physiological functions and the evolution of amylin-based therapies, from key properties to clinical significance.
Long-term SGLT2 inhibitor use is associated with an increased risk for postoperative euglycemic ketoacidosis but lower risks for postoperative acute kidney injury and mortality.
Understand the pathogenic mechanisms underlying diabetic foot development in patients with rheumatic diseases, the impact of chronic inflammation and drug therapy, and current diagnostic approaches, treatment strategies, and preventive measures.
A 64-year-old man with type 1 diabetes presented with notable abdominal swelling over the previous 3 months. Investigations led to a diagnosis of pseudoascites and celiac disease was identified as the cause.
The diabetes and obesity treatment semaglutide, a GLP-1 receptor agonist, reduces liver fibrosis and steatohepatitis in adults with MASH, suggests an interim analysis of the ESSENCE trial.
Obesity is a major contributor to cardiorenal metabolic disease, but its impact extends throughout the body. Understand how obesity can affect other organ systems and impact treatment, and whether weight-loss measures improve outcomes.
With the growing importance of primary care in diabetes, this podcast discusses the evidence on continuous glucose monitoring (CGM) use, the role of primary healthcare, and practical tips for interpreting the ambulatory glucose profile (AGP) report.
A 64-year-old man with type 1 diabetes presented with notable abdominal swelling over the previous 3 months. Investigations led to a diagnosis of pseudoascites and celiac disease was identified as the cause.
Cutaneous lymphoma should be considered in patients with long-standing, poorly controlled type 2 diabetes and chronic non-healing skin lesions. In this case, primary cutaneous B-cell lymphoma was misdiagnosed as a skin infection.
Although it seems to be a rare complication, there should be a high index of suspicion for colonic ischemia in patients taking a GLP-1 receptor agonist who present with abdominal pain.
The management of type 2 diabetes has evolved significantly with the advent of incretin-based therapies, particularly dipeptidyl peptidase-4 inhibitors and glucagon-like peptide-1 receptor agonists. In Japan, where over 70% of individuals with …
The global surge in obesity and type 2 diabetes mellitus (T2DM) presents significant challenges in orthopedic care, directly impacting musculoskeletal health and surgical outcomes. These metabolic disorders are associated with increased rates of …
In 2021, one in ten adults , i.e., 537 million people were living with diabetes mellitus worldwide. It is predicted that this number will increase to 783 million by 2045. Diabetes mellitus brings many complications, of which bone fragility is the …
Diabetic neuropathy (DNP) is a common complication of diabetes that has a significant impact on the patient’s quality of life. The primary objectives of clinical treatment for DNP these days are symptomatic pain management and glycemic control.
Despite many recent advances in its management, type 1 diabetes remains a burden for those living with the condition.
Prof. Chantal Mathieu explains the progress being made with disease-modifying therapy for type 1 diabetes and how it has the potential to transform the current treatment landscape.
Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills.
Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.
This program is not available to users in the UK and US.
Treating children with hormone disorders is complex and requires tailored management. To help you provide the most effective care, we deliver resources covering adrenal, thyroid, pituitary, growth, and puberty disorders, obesity, and diabetes.
Diabetes represents one of the most rapidly escalating health challenges of the twenty-first century, with the global prevalence of diabetes among adults increasing more than threefold over the past two decades [ 1 ]. In 2021, approximately 10.5% …
The alpha cells of the pancreatic islets of Langerhans play a pivotal role in glucose homeostasis by secreting counterregulatory glucagon in response to low glucose levels, and this stimulates hepatic glucose output to prevent hypoglycaemia [ 1 ].
The management of type 2 diabetes has evolved significantly with the advent of incretin-based therapies, particularly dipeptidyl peptidase-4 inhibitors and glucagon-like peptide-1 receptor agonists. In Japan, where over 70% of individuals with …
The global surge in obesity and type 2 diabetes mellitus (T2DM) presents significant challenges in orthopedic care, directly impacting musculoskeletal health and surgical outcomes. These metabolic disorders are associated with increased rates of …
Is amylin the missing piece of the puzzle when it comes to precision diabetology? Explore amylin’s diverse physiological functions and the evolution of amylin-based therapies, from key properties to clinical significance.
Is amylin the missing piece of the puzzle when it comes to precision diabetology? Explore amylin’s diverse physiological functions and the evolution of amylin-based therapies, from key properties to clinical significance.
Understand the pathogenic mechanisms underlying diabetic foot development in patients with rheumatic diseases, the impact of chronic inflammation and drug therapy, and current diagnostic approaches, treatment strategies, and preventive measures.
A thorough overview of the safety and efficacy of once-weekly basal insulin icodec in type 1 and 2 diabetes, covering pharmacology, pharmacokinetics, adverse effects, drug interactions, and dose recommendations.