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Diabetology

Sleep health important after gestational diabetes

Shorter sleep duration and both regular and occasional snoring are linked to an increased risk for type 2 diabetes in women with a history of gestational diabetes.

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Editor's Choice

Advances in assessing myocardial microcirculation in diabetes

Imaging techniques are enhancing our understanding of the myocardial microcirculation and providing insights into the early stages of microvascular dysfunction in people with diabetes.

Modest increase in NAION risk with semaglutide

Increased risk for nonarteritic anterior ischemic optic neuropathy associated with semaglutide treatment in people with type 2 diabetes is not as great as previously reported.

Novel berberine-based treatment for type 2 diabetes

Berberine ursodeoxycholate, a gut–liver anti-inflammatory metabolic modulator, significantly reduces HbA1c and improves hepatic and cardiometabolic parameters in people with type 2 diabetes.

Minimizing glycemic variability in type 1 diabetes

Recommendations proposed to reduce glycemic variability and improve glycemic management in people with type 1 diabetes, focusing on physical activity, dietary habits, insulin therapy, and other causes of increased variability.

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At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
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Using CGM to optimize type 2 diabetes management with non-intensive insulin treatment in primary care

With the growing importance of primary care in diabetes, this podcast discusses the evidence on continuous glucose monitoring (CGM) use, the role of primary healthcare, and practical tips for interpreting the ambulatory glucose profile (AGP) report. 

Supported by:
  • Abbott Diabetes Care
Prof. Samuel Seidu
Developed by: Adis
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Podcast

Case Studies

Delayed diagnosis of monogenic diabetes

Complete heterozygous deletion of HNF1B was incidentally discovered in a woman who was enrolled in a clinical trial for type 1 diabetes and received immunosuppressive treatment for 4 years when she was a child.

Semaglutide for comorbid obesity and cocaine use disorder

Semaglutide therapy achieved weight loss and reduced cocaine craving in a man with obesity and chronic cocaine abuse. Could this be a new strategy to address substance craving in patients with comorbid obesity?

Treatment of MODY with an SGLT2 inhibitor

Adding empagliflozin to sulfonylurea improved glycemic control in a woman with maturity-onset diabetes of the young. No adverse effects were noted, including no increase in ketonemia or ketonuria.

Episode 10: Disease-modifying therapy for type 1 diabetes

Reducing the burden of type 1 diabetes

Despite many recent advances in its management, type 1 diabetes remains a burden for those living with the condition.

Prof. Chantal Mathieu explains the progress being made with disease-modifying therapy for type 1 diabetes and how it has the potential to transform the current treatment landscape.

Prof. Chantal Mathieu
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Podcast

Current Reviews

Effect of Verapamil on Blood Glucose in Type 1 and Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

Type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) are characterized by insufficient insulin secretion and insulin resistance, respectively. Both conditions require the restoration of islet cell function and maintenance of higher …

Preconception Physical Activity and Maternal Health Outcomes: An Integrative Review of Studies from 2016–2025

Performing regular physical activity (PA) throughout the lifespan, including during a woman’s preconception years (defined as the time period in which women desire and intend to conceive a child; Hill et al., 2020 ), is critical for overall health …

Sex Differences in Obesity and Its Treatment

In the past three decades, the prevalence of obesity in adults increased in almost every country among both females and males [ 1 ]. During this time, the age-standardized prevalence of obesity rose by more than 20% points in 49 countries (25% of …

Combining SGLT2is, GLP1-RAs and nsMRAs in Diabetes: A Scoping Review of Current and Future Perspectives

Combination therapy is a cornerstone of modern type 2 diabetes management, extending beyond traditional goals of glucose, blood pressure, and lipid control to focus on therapies protecting the heart and kidneys. The introduction of sodium-glucose …

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.

Developed by: Springer Medicine
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CME & eLearning

Videos | Case Scenarios | Infographics (Link opens in a new window)

1.0 AMA PRA Category 1 Credit(s)

Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Tweetorials | Vodcasts | Infographics (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)

Stay up to date with the rapidly changing CGM landscape. Learn how to implement and integrate CGM into diabetes management to improve patient care and outcomes.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Vodcasts | Case Scenarios (Link opens in a new window)

Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Further Reading

Modulation of the cognitive impairment associated with Alzheimer’s disease by valproic acid: possible drug repurposing

Sporadic Alzheimer’s disease is a progressive neurodegenerative disorder affecting the central nervous system. Its main two hallmarks are extracellular deposition of aggregated amyloid beta resulting in senile plaques and intracellular …

Clinical Profile and Treatment Patterns in Individuals with Type 2 Diabetes and Chronic Kidney Disease Who Initiate a GLP-1 Receptor Agonist: A Multinational Cohort Study

Type 2 diabetes (T2D) is a major cause of chronic kidney disease (CKD) worldwide [ 1 , 2 ]. Diabetes with CKD is the most common underlying cause of kidney failure, accounting for almost 50% of cases in the developed world [ 3 ]. Additionally …

The Prevalence of Atherosclerotic Cardiovascular Disease in Patients with Type 2 Diabetes in Jordan: The PACT-MEA Study

Type 2 diabetes (T2D) is a global epidemic. In 2021, nearly 11% of the world’s population had T2D, contributing to more than 6.7 million deaths [ 1 ]. The Middle East and North Africa (MENA) region has the highest regional prevalence of T2D at …

Knowledge, Attitudes, and Practices in Neonatal Diabetes Mellitus Management: the JEnious-NeOnatal-DIabetes (JENODI) Survey

Neonatal diabetes mellitus (NDM) is a monogenic form of diabetes diagnosed within the first 6 months of life [ 1 ]. It is a rare disease with a global incidence that varies, with the highest rate reported among the highly consanguineous Arab …