Explore the integration of semaglutide with medical nutritional therapy for the comprehensive management of obesity, with a focus on the Mediterranean diet and very-low-energy ketogenic therapy.
Liraglutide may reduce recurrent stroke risk versus placebo in people with type 2 diabetes with minor acute ischemic stroke or high-risk transient ischemic attack.
Explore the diverse roles of adiponectin and its effects on cardiovascular outcomes across diabetes subtypes, especially in diabetic cardiomyopathy, with an emphasis on congestive heart failure.
What could be causing involuntary and uncontrolled movements in the right arm and leg of a woman with a 25-year history of diabetes and hypertension, beginning shortly after an intramuscular betamethasone injection for shoulder pain?
In 2005 the US FDA approved the first GLP-1 medicine for type 2 diabetes, marking the start of a remarkable journey that goes beyond the stimulation of insulin secretion.
Prof. Daniel Drucker gives us a fascinating insight into the early work on GLP-1 and discusses how these medicines are impacting the lives of people with diabetes and obesity. He covers what's known about how they work, treatment duration, side effects, and the role of bariatric surgery, plus what's in the pipeline in terms of drug development and the indications that GLP-1 medicines may be used to treat in the future.
Obesity is a major contributor to cardiorenal metabolic disease, but its impact extends throughout the body. Understand how obesity can affect other organ systems and impact treatment, and whether weight-loss measures improve outcomes.
What could be causing involuntary and uncontrolled movements in the right arm and leg of a woman with a 25-year history of diabetes and hypertension, beginning shortly after an intramuscular betamethasone injection for shoulder pain?
A man who achieved diabetes remission after gastric bypass presented with hypoglycemic episodes and endogenous hyperinsulinemia. Hypoglycemia resolved and fasting tests normalized when sacubitril/valsartan was discontinued due to worsening renal function.
A woman with abdominal pain was diagnosed with ureteral stones, but her pain persisted despite stent placement. A prior diagnosis of type 2 diabetes led to diabetic ketoacidosis being identified as the cause of the pain.
Prof. Chantal Mathieu highlights how the absence of rigorous performance standards for continuous glucose monitors in Europe contributes to wide variability in device accuracy, raising important concerns about patient safety.
The pathogenesis of diabetic retinopathy DR is highly complex, and in recent years, increasing attention has been directed toward the role of the gut in its development. Evidence suggests that intestinal barrier dysfunction is a frequent …
Mitochondrial dysfunction plays a crucial role in the pathophysiology of Type 1 Diabetes (T1D), as it compromises beta (β)-cell survival and insulin secretion. Autoimmune-driven inflammation disrupts mitochondrial homeostasis and thereby induces …
The NOD mouse is the best-known, although by no means the only, murine model of type 1 diabetes. In this review, we provide a historical perspective, particularly highlighting areas of progress in understanding aspects of aetiology and immune …
Skeletal muscle wasting is a major yet often overlooked determinant of adverse outcomes in diabetes mellitus and obesity. Loss of muscle mass and strength not only impairs mobility and quality of life, but also worsens insulin resistance …
Familiarize yourself with current and emerging ketone monitoring systems and the most useful clinical scenarios in which to use them through our podcasts and e-learning modules. Lower the barriers to effective prevention of diabetic ketoacidosis.
Prof. Chantal Mathieu highlights how the absence of rigorous performance standards for continuous glucose monitors in Europe contributes to wide variability in device accuracy, raising important concerns about patient safety.
Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills with real cases, vodcasts, and interactive infographics.
Diabetic foot ulcer (DFU) is a common and severe complication of diabetes that leads to amputation if not effectively managed. Intelligent offloading or rehabilitation devices or boots are used to manage or observe the ulcer and the process of …
Obesity represents a global public health burden. It is typically interrelated to a plethora of complications that predispose to avoidable morbidity and mortality [ 1 ]. The rates of obesity worldwide have more than doubled over the past 35 years …
Diabetes mellitus (DM) is a chronic metabolic disorder with an increasing global prevalence [ 1 , 2 ]. While vascular complications are well-characterized, musculoskeletal manifestations are also common, yet often overlooked [ 3 ]. Notably …
Islet amyloid formation is considered an important pathological characteristic of pancreatic islets in individuals with type 2 diabetes [ 1 – 3 ], while it can also be identified in some individuals with type 1 diabetes [ 4 , 5 ] or less commonly …
Explore the integration of semaglutide with medical nutritional therapy for the comprehensive management of obesity, with a focus on the Mediterranean diet and very-low-energy ketogenic therapy.
Explore the integration of semaglutide with medical nutritional therapy for the comprehensive management of obesity, with a focus on the Mediterranean diet and very-low-energy ketogenic therapy.
Explore the diverse roles of adiponectin and its effects on cardiovascular outcomes across diabetes subtypes, especially in diabetic cardiomyopathy, with an emphasis on congestive heart failure.
A man who achieved diabetes remission after gastric bypass presented with hypoglycemic episodes and endogenous hyperinsulinemia. Hypoglycemia resolved and fasting tests normalized when sacubitril/valsartan was discontinued due to worsening renal function.
