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The bidirectional link between diabetes and periodontitis is well established, but periodontitis remains underdiagnosed in the context of diabetes. Coordinated care could improve inflammation, oral health, and metabolic outcomes.
Hypertension and prediabetes in combination with subclinical myocardial injury or stress associated with significantly elevated risk for heart failure.
Using tirzepatide with systemic hormone therapy improves weight loss and cardiometabolic outcomes versus tirzepatide alone in postmenopausal women with overweight or obesity.
Insulin remains key to the management of type 2 diabetes, but its role continues to evolve with the arrival of once-weekly regimens presenting new opportunities and challenges. How can once-weekly insulin therapy be implemented to optimize patient care?
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Prof. Chantal Mathieu highlights how the absence of rigorous performance standards for continuous glucose monitors in Europe contributes to wide variability in device accuracy, raising important concerns about patient safety.
A 37-year-old woman developed acute encephalopathy and treatment-induced neuropathy of diabetes after 3 months of semaglutide use. Benefits of GLP-1 agonists outweigh the risks, but clinicians should be alert to potential sequelae.
A unusual case of bilateral lower-leg edema that developed in an older woman with SPIDDM shortly after she started basal–bolus insulin therapy with insulin aspart and insulin degludec.
What could be causing involuntary and uncontrolled movements in the right arm and leg of a woman with a 25-year history of diabetes and hypertension, beginning shortly after an intramuscular betamethasone injection for shoulder pain?
In this special edition of Medicine Matters, we're joined by Dr Gregory Lim, Claire Greenhill, and Sarah Onuora, Chief Editors of Nature Reviews Cardiology, Endocrinology, and Rheumatology, for a look back at the advances in their specialties in 2025.
Find out what caught their attention and why, and what they're looking forward to in 2026.
Three diseases primarily affecting the exocrine pancreas—chronic pancreatitis, cystic fibrosis and pancreatic ductal adenocarcinoma—are all associated with a high incidence of diabetes. Together, they may account for more cases of diabetes than …
A systematic review and network meta-analysis was implemented to compare social support interventions for glycemic control in people with type 2 diabetes from low- and middle-income countries (LMICs) and those from racial and ethnic minoritized …
Diabetic retinopathy (DR) is a microangiopathic disease, resulting from the chronic effects of diabetes mellitus (DM). A total of 103 million adults worldwide are estimated to be affected by DR, which is expected to rise to 161 million individuals …
Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, responsible for approximately 17.9 million deaths annually [ 1 ]. Among all the factors contributing to CVD, Obesity plays a dominant role by promoting CVD risk …
In 2005 the US FDA approved the first GLP-1 medicine for type 2 diabetes, marking the start of a remarkable journey that goes beyond the stimulation of insulin secretion.
Prof. Daniel Drucker gives us a fascinating insight into the early work on GLP-1 and discusses how these medicines are impacting the lives of people with diabetes and obesity. He covers what's known about how they work, treatment duration, side effects, and the role of bariatric surgery, plus what's in the pipeline in terms of drug development and the indications that GLP-1 medicines may be used to treat in the future.
Familiarize yourself with current and emerging ketone monitoring systems and the most useful clinical scenarios in which to use them through our podcasts and e-learning modules. Lower the barriers to effective prevention of diabetic ketoacidosis.
Prof. Chantal Mathieu highlights how the absence of rigorous performance standards for continuous glucose monitors in Europe contributes to wide variability in device accuracy, raising important concerns about patient safety.
Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills with real cases, vodcasts, and interactive infographics.
Endometrial cancer (EC) is the most common gynecological tumor, ranking fourth in incidence and fifth in mortality among the female population in the United States [ 1 ]. In 2022, 77,700 new EC cases was reported in China, which made up more than …
Polyneuropathy affects up to 50% of people with diabetes, leading to increased morbidity and reduced quality of life [ 1 – 6 ]. To reduce the increased morbidity, early diagnosis is necessary to enable early therapeutic interventions [ 7 ]. Here …
Type 1 diabetes and coeliac disease are autoimmune conditions with specific autoantibodies detectable years before clinical onset. Though historically viewed as paediatric disorders, both affect individuals across all age groups, with variable …
Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of death among patients with DM, who frequently present with extensive multivessel coronary artery disease and poor long-term outcomes. Although treatment strategies for MI …
The bidirectional link between diabetes and periodontitis is well established, but periodontitis remains underdiagnosed in the context of diabetes. Coordinated care could improve inflammation, oral health, and metabolic outcomes.
The bidirectional link between diabetes and periodontitis is well established, but periodontitis remains underdiagnosed in the context of diabetes. Coordinated care could improve inflammation, oral health, and metabolic outcomes.
Metformin improves maternal glucose levels and lowers neonatal hypoglycemia risk versus standard care in women given antenatal betamethasone due to preterm delivery risk.