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IL-17A is gaining recognition for its potential role in DKD and could represent a promising therapeutic target. Examine the latest research findings and potential mechanisms underlying the cytokine’s involvement in DKD.
Emerging evidence highlights ferroptosis as a key player in the progression of diabetic cardiomyopathy. Discover the mechanistic links between ferroptosis and DCM, and the promising therapeutic strategies targeting them.
Explore the recommendations from the European Diabetes Forum working group, convened to examine good diabetes care in the context of AI-driven clinical decision support systems.
Gain patient and physician insights on managing diabetic macular edema, including current challenges with anti-VEGF injections, and emerging strategies to reduce treatment burden and improve outcomes.
Reframing obesity-related metabolic disorders as progressive stages within a continuous and dynamic process of metabolic dysfunction could facilitate more accurate risk assessment, earlier intervention, and coordinated care.
In 2005 the US FDA approved the first GLP-1 medicine for type 2 diabetes, marking the start of a remarkable journey that goes beyond the stimulation of insulin secretion.
Prof. Daniel Drucker gives us a fascinating insight into the early work on GLP-1 and discusses how these medicines are impacting the lives of people with diabetes and obesity. He covers what's known about how they work, treatment duration, side effects, and the role of bariatric surgery, plus what's in the pipeline in terms of drug development and the indications that GLP-1 medicines may be used to treat in the future.
Obesity is a major contributor to cardiorenal metabolic disease, but its impact extends throughout the body. Understand how obesity can affect other organ systems and impact treatment, and whether weight-loss measures improve outcomes.
What could be causing involuntary and uncontrolled movements in the right arm and leg of a woman with a 25-year history of diabetes and hypertension, beginning shortly after an intramuscular betamethasone injection for shoulder pain?
A man who achieved diabetes remission after gastric bypass presented with hypoglycemic episodes and endogenous hyperinsulinemia. Hypoglycemia resolved and fasting tests normalized when sacubitril/valsartan was discontinued due to worsening renal function.
A woman with abdominal pain was diagnosed with ureteral stones, but her pain persisted despite stent placement. A prior diagnosis of type 2 diabetes led to diabetic ketoacidosis being identified as the cause of the pain.
Prof. Chantal Mathieu highlights how the absence of rigorous performance standards for continuous glucose monitors in Europe contributes to wide variability in device accuracy, raising important concerns about patient safety.
Chronic obstructive pulmonary disease (COPD) is a heterogeneous chronic lung condition often accompanied by comorbidities and systemic manifestations that affect the person’s clinical condition and prognosis and often require specific treatment.
With the rising incidence of type 2 diabetes mellitus (T2DM) worldwide, the search for effective treatments has become an important direction of contemporary medical research. Bariatric metabolic surgery, as a new therapeutic approach, has made …
Obesity is defined as a medical condition caused by an imbalance between energy intake and energy consumption in the body [ 1 ]. In 2016, the World Health Organization reported that over 1.9 billion adults were overweight, with more than 650 …
In the last several years genome sequencing technology has become significantly less expensive and faster [ 1 ]. This has opened the door to broader access to genetic testing for patients for a multitude of likely genetic conditions including …
Familiarize yourself with current and emerging ketone monitoring systems and the most useful clinical scenarios in which to use them through our podcasts and e-learning modules. Lower the barriers to effective prevention of diabetic ketoacidosis.
Prof. Chantal Mathieu highlights how the absence of rigorous performance standards for continuous glucose monitors in Europe contributes to wide variability in device accuracy, raising important concerns about patient safety.
Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills with real cases, vodcasts, and interactive infographics.
Diabetes is a major health issue with an increasing prevalence worldwide, posing challenges at different levels [ 1 ]. Diabetes imposes a burden on both the affected individuals and the health care systems [ 2 ], as it is associated with …
In the last several years genome sequencing technology has become significantly less expensive and faster [ 1 ]. This has opened the door to broader access to genetic testing for patients for a multitude of likely genetic conditions including …
The phosphatidylinositol 3-kinase (PI3K)/Akt serine/threonine kinase (AKT) signaling pathway is an important signaling pathway regulating cell proliferation and survival [ 1 , 2 ]. Hyperactivation of the pathway due to PTEN deficiency or activating …
Doege-Potter syndrome in solitary fibrous tumor of the retroperitoneum is rare. Here, we present a 45 years old Chinese male patient who was admitted to our center after discovering an abdominal mass for 5 years and intermittent episodes of …
Emerging evidence highlights ferroptosis as a key player in the progression of diabetic cardiomyopathy. Discover the mechanistic links between ferroptosis and DCM, and the promising therapeutic strategies targeting them.
Explore the recommendations from the European Diabetes Forum working group, convened to examine good diabetes care in the context of AI-driven clinical decision support systems.
IL-17A is gaining recognition for its potential role in DKD and could represent a promising therapeutic target. Examine the latest research findings and potential mechanisms underlying the cytokine’s involvement in DKD.
A man who achieved diabetes remission after gastric bypass presented with hypoglycemic episodes and endogenous hyperinsulinemia. Hypoglycemia resolved and fasting tests normalized when sacubitril/valsartan was discontinued due to worsening renal function.