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Peripheral nerve stimulation for neuropathic pain

Global prevalence of neuropathic pain is 6.9–10%. Drug treatments have limited efficacy for many people, but PNS is a promising alternative with minimal side effects.

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Editor's Choice

Leaky gut: causes, diseases, and therapy

Excessive intestinal barrier permeability is increasingly being diagnosed, but what do we know about the causes and potential health consequences? Can intestinal barrier damage be prevented or repaired?

Is heart failure a risk factor for cancer?

The causal effect of cancer and cancer therapies on the development of heart failure is well known, but what about the other way around? Explore the evidence for the pathophysiological pathways linking tumor growth with heart failure.

Focus on latent autoimmune diabetes in adults

LADA shares features with type 1 and 2 diabetes, but deeper understanding of the disease is vital. Discover what’s known about its pathogenesis, clinical features, diagnosis, prognosis, and treatment.

OGTT superior for cardiovascular risk prediction in people with CAD

Two-hour post-load glucose is better at detecting dysglycemia and predicting cardiovascular events than HbA1c in patients with coronary artery disease.

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At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
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Using CGM to optimize type 2 diabetes management with non-intensive insulin treatment in primary care

With the growing importance of primary care in diabetes, this podcast discusses the evidence on continuous glucose monitoring (CGM) use, the role of primary healthcare, and practical tips for interpreting the ambulatory glucose profile (AGP) report. 

Supported by:
  • Abbott Diabetes Care
Prof. Samuel Seidu
Developed by: Adis
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Case Studies

Maternally inherited diabetes and deafness

Genetic testing was needed to diagnose the mitochondrial disorder MIDD in a woman with diabetes, weight loss, and poor glycemic control. Glycated hemoglobin and pancreatic function improved after treatment with a DPP-4 inhibitor.

Stevens-Johnson syndrome/toxic epidermal necrolysis complicated with fulminant type 1 diabetes

A rare case of fulminant type 1 diabetes induced by SJS/TEN, which had developed in a patient taking carbamazepine and phenytoin. Glucose monitoring should be considered for patients with SJS/TEN.

Accidental use of dulaglutide into the third trimester

The GLP-1 receptor agonist dulaglutide was unintentionally used by a woman with type 2 diabetes until the third trimester of an unplanned and unrecognized pregnancy, but what was the outcome?

Episode 10: Disease-modifying therapy for type 1 diabetes

Reducing the burden of type 1 diabetes

Despite many recent advances in its management, type 1 diabetes remains a burden for those living with the condition.

Prof. Chantal Mathieu explains the progress being made with disease-modifying therapy for type 1 diabetes and how it has the potential to transform the current treatment landscape.

Prof. Chantal Mathieu
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Current Reviews

The homeo-FIT-prolactin hypothesis: the role of prolactin in metabolic homeostasis – association or causality?

The homeo-fit-prolactin hypothesis proposes a causal metabolic role for prolactin with hypoprolactinemia and hyperprolactinemia leading to adverse metabolic alterations. However, prolactin within the normal range and up to four times the upper …

Impact of pesticides exposure and type 2 diabetes risk: a systematic review and meta-analysis

The worldwide prevalence of diabetes continues to rise, with projections indicating that there will be ~783.2 million individuals aged 20–79 affected by the condition by 2045 [ 1 ]. Type 2 diabetes comprises around 90% of all cases and exerts a …

Clinical research progress on β-cell dysfunction in T2DM development in the Chinese population

The prevalence of type-2 diabetes mellitus (T2DM) has increased over 10-fold in the past 40 years in China, which now has the largest T2DM population in the world. Insulin resistance and β-cell dysfunction are the typical features of T2DM.

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.

Developed by: Springer Medicine
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CME & eLearning

Videos | Case Scenarios | Infographics (Link opens in a new window)

1.0 AMA PRA Category 1 Credit(s)

Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Tweetorials | Vodcasts | Infographics (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)

Stay up to date with the rapidly changing CGM landscape. Learn how to implement and integrate CGM into diabetes management to improve patient care and outcomes.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Vodcasts | Case Scenarios (Link opens in a new window)

Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Further Reading

Glucose metrics and device satisfaction in adults with type 1 diabetes using different treatment modalities: a multicenter, real-world observational study

Type 1 diabetes is a lifelong disease requiring intensive insulin treatment and daily monitoring of blood glucose levels. Despite efforts to maintain the glucose levels as close as possible to the recommended target, the majority of patients do …

Addressing disparities in the long-term mortality risk in individuals with non-ST segment myocardial infarction (NSTEMI) by diabetes mellitus status: a nationwide cohort study

  • Open Access
  • Diabetes
  • Original Research

Acute myocardial infarction (AMI) is the leading cause of mortality globally [ 1 ], with the incidence of non-ST segment myocardial infarction (NSTEMI), in particular, increasing [ 2 ]. Diabetes mellitus is an important risk factor for NSTEMI, with …

Progression to type 1 diabetes in the DPT-1 and TN07 clinical trials is critically associated with specific residues in HLA-DQA1-B1 heterodimers

Type 1 diabetes is a life-long chronic autoimmune disease with an annual incidence among young people (under 20 years) of around 130,000 worldwide [ 1 ]. Its development typically runs from seroconversion (stage 1) to hyperglycaemia (stage 2), to …

Continuous glucose monitoring in patients with inherited metabolic disorders at risk for Hypoglycemia and Nutritional implications

Managing Inherited Metabolic Disorders (IMDs) at risk for hypoglycemia, such as Glycogen Storage Diseases (GSDs), Hereditary Fructose Metabolism Disorders (HFMDs) and Congenital Hyperinsulinism (CH), poses challenges in dietary treatments and …

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