Including anthropometric criteria in the definition of obesity increases prevalence by nearly 60% compared with the traditional BMI-based classification.
Major adverse cardiovascular event risk in people with type 2 diabetes varies by the type of glucose-lowering medication used, with GLP-1 receptor agonists offering the greatest protection.
Early detection of foot ulcers in people with diabetes is vital but difficult to achieve due to the complex interaction of neuropathy, vascular disease, and immune dysfunction. Is thermal imaging the answer?
Emerging evidence suggests SGLT2 inhibitors may help to prevent or slow neurodegeneration. Review their mechanisms of action and therapeutic potential.
Platelets are a key factor in the micro- and macrovascular complications of diabetes. Explore the platelet changes that occur, underlying molecular mechanisms, the role in vascular complications, and therapeutic perspectives.
In 2005 the US FDA approved the first GLP-1 medicine for type 2 diabetes, marking the start of a remarkable journey that goes beyond the stimulation of insulin secretion.
Prof. Daniel Drucker gives us a fascinating insight into the early work on GLP-1 and discusses how these medicines are impacting the lives of people with diabetes and obesity. He covers what's known about how they work, treatment duration, side effects, and the role of bariatric surgery, plus what's in the pipeline in terms of drug development and the indications that GLP-1 medicines may be used to treat in the future.
Obesity is a major contributor to cardiorenal metabolic disease, but its impact extends throughout the body. Understand how obesity can affect other organ systems and impact treatment, and whether weight-loss measures improve outcomes.
A man who achieved diabetes remission after gastric bypass presented with hypoglycemic episodes and endogenous hyperinsulinemia. Hypoglycemia resolved and fasting tests normalized when sacubitril/valsartan was discontinued due to worsening renal function.
A woman with abdominal pain was diagnosed with ureteral stones, but her pain persisted despite stent placement. A prior diagnosis of type 2 diabetes led to diabetic ketoacidosis being identified as the cause of the pain.
A woman with type 1 diabetes experienced long-term metabolic improvements after pancreatic islet transplantation, but the onset of neurological symptoms led to monogenic Wolfram syndrome being diagnosed as the cause of her diabetes.
Prof. Chantal Mathieu highlights how the absence of rigorous performance standards for continuous glucose monitors in Europe contributes to wide variability in device accuracy, raising important concerns about patient safety.
Polycystic Ovary Syndrome (PCOS) is an amalgamation of several factors such as complex combination of endocrine and metabolic disorder caused due to insulin resistance, hyperandrogenism and chronic inflammation. Research shows that postbiotics and …
Diabetic cardiomyopathy (DCM) is a common complication of diabetes, characterized by myocardial injury, fibrosis, and heart dysfunction. The pathogenesis remains poorly understood, with limited treatment options. Recent research highlights the …
Artificial intelligence (AI) is progressively advancing across various medical specialties, particularly ophthalmology, to evaluate medical data, prevent diseases, and facilitate individualized treatment strategies. This narrative review …
Fluid, electrolyte, and energy (FEE) management plays a crucial role in the recovery of patients with type 2 diabetes mellitus (T2DM) and prediabetes, especially during acute non-diarrheal illnesses. However, current diabetes management guidelines …
Familiarize yourself with current and emerging ketone monitoring systems and the most useful clinical scenarios in which to use them. Lower the barriers to effective prevention of diabetic ketoacidosis.
Prof. Chantal Mathieu highlights how the absence of rigorous performance standards for continuous glucose monitors in Europe contributes to wide variability in device accuracy, raising important concerns about patient safety.
Treating children with hormone disorders is complex and requires tailored management. To help you provide the most effective care, we deliver resources covering adrenal, thyroid, pituitary, growth, and puberty disorders, obesity, and diabetes.
This study demonstrates that empagliflozin use is associated with a slower decline in renal function compared to sitagliptin in Korean patients with type 2 diabetes in a real-world setting. By emulating a target trial using EMR data, our findings …
Prediabetes affects over 350 million individuals worldwide and is increasingly recognized as a systemic risk condition predisposing to cardiovascular and cerebrovascular events [ 1 ]. Despite its high prevalence in older patients, it often remains …
The increasing prevalence of diabetes mellitus and its complications has become a serious global health concern. To prevent diabetes-related complications, many countries have developed standardized treatment guidelines. In Japan, a large …
Type 2 diabetes is characterised by hyperglycaemia resulting from insulin deficiency and/or insulin resistance [ 1 ], and is one of the most prevalent chronic diseases globally, causing life-threatening complications [ 2 ]. An estimated 537 million …
Including anthropometric criteria in the definition of obesity increases prevalence by nearly 60% compared with the traditional BMI-based classification.
Major adverse cardiovascular event risk in people with type 2 diabetes varies by the type of glucose-lowering medication used, with GLP-1 receptor agonists offering the greatest protection.
Major adverse cardiovascular event risk in people with type 2 diabetes varies by the type of glucose-lowering medication used, with GLP-1 receptor agonists offering the greatest protection.
A man who achieved diabetes remission after gastric bypass presented with hypoglycemic episodes and endogenous hyperinsulinemia. Hypoglycemia resolved and fasting tests normalized when sacubitril/valsartan was discontinued due to worsening renal function.
