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Obesity-related heart failure with preserved ejection fraction is increasingly recognized as a multiorgan cardio-renal-hepatic-metabolic syndrome but is not adequately addressed by conventional HF therapies. Is it time to rethink our approach?
Incretin-based therapies have transformed obesity care, and new-generation therapies targeting multiple metabolic pathways aim to build on this success. What do we know so far about their mechanisms, efficacy, and safety?
Glucocorticoid-induced diabetes represents an important yet often overlooked complication of GC therapy. Review the current knowledge on the mechanisms, prevalence, and risk factors in patients with autoimmune rheumatic diseases.
The first of three podcast episodes on the identification and management of heart failure in people with diabetes, with practical guidance from a cardiovascular specialist, an endocrinologist, and a primary care physician.
Men with type 2 diabetes starting GLP-1 receptor agonists may have a modestly higher risk for erectile dysfunction risk than those given DPP4 inhibitors.
Enhance your knowledge of the advances being made with GLP-1 medicines with our clinical collection. Discover the latest news stories and journal articles or take a deep dive into our clinical trial summary, podcast, and video series.
Prof. Chantal Mathieu highlights how the absence of rigorous performance standards for continuous glucose monitors in Europe contributes to wide variability in device accuracy, raising important concerns about patient safety.
Glucocorticoid-induced diabetes represents an important yet often overlooked complication of GC therapy. Review the current knowledge on the mechanisms, prevalence, and risk factors in patients with autoimmune rheumatic diseases.
Semaglutide use in a man with type 2 diabetes and spinal and bulbar muscular atrophy treated with leuprorelin. Over 2 years glycemic parameters improved and fat mass reduced, with only a minor annual decrease in muscle mass.
A case of fulminant type 1 diabetes in a woman on tislelizumab for lung adenocarcinoma highlights the need for proactive monitoring of fasting glucose, HbA1c, and islet function in people given an immune checkpoint inhibitor.
Insulin remains key to the management of type 2 diabetes, but its role continues to evolve with the arrival of once-weekly regimens presenting new opportunities and challenges. Learn how once-weekly insulin therapy be implemented to optimize patient care.
Type 2 Diabetes Mellitus (T2DM) is an escalating public health issue in Southeast Asia, propelled by swift urbanization, inactive lifestyles, and changes in food habits. The International Diabetes Federation (IDF) indicated that in 2021, Southeast …
The human microbiome has an enormous and multifaceted ecosystem of microorganisms like fungi, protozoa, bacteria, and viruses that live in our bodies, mainly in the gut, and is crucial in maintaining our health. The published evidence supports …
Diabetes mellitus is a systemic metabolic disease that causes a wide spectrum of complications affecting multiple organs. Advances in imaging modalities have substantially improved the detection, characterization, and clinical management of these …
Cystic fibrosis (CF) is a monogenic disorder leading to pulmonary disease, pancreatic insufficiency and cystic fibrosis-related diabetes (CFRD). Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are now being investigated in people with cystic …
In this special edition of Medicine Matters, we're joined by Dr Gregory Lim, Claire Greenhill, and Sarah Onuora, Chief Editors of Nature Reviews Cardiology, Endocrinology, and Rheumatology, for a look back at the advances in their specialties in 2025.
Find out what caught their attention and why, and what they're looking forward to in 2026.
Familiarize yourself with current and emerging ketone monitoring systems and the most useful clinical scenarios in which to use them through our podcasts and e-learning modules. Lower the barriers to effective prevention of diabetic ketoacidosis.
Prof. Chantal Mathieu highlights how the absence of rigorous performance standards for continuous glucose monitors in Europe contributes to wide variability in device accuracy, raising important concerns about patient safety.
Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills with real cases, vodcasts, and interactive infographics.
Obesity and overweight are the most common modifiable etiologic risk factors for type 2 diabetes (T2D). The global prevalence of obesity is expected to grow to 1.13 billion by 2030 [ 1 ]. Furthermore, the prevalence of prediabetes in adults is also …
Fracture risk in type 2 diabetes mellitus (T2DM) is increasingly recognized as a clinically important yet underappreciated complication. Despite patients with T2DM often presenting with normal or even elevated bone mineral density (BMD), numerous …
Current clinical management of type 1 diabetes (T1D) with insulin and continuous glucose monitors (CGMs) and/or automated insulin delivery systems (AID) is focused on maintaining glucose levels in a narrow range and hemoglobin A1c (HbA1c) ≤ 7% to …
Lower urinary tract symptoms (LUTS) has been defined as a series of clinical symptoms indicating bladder storage and voiding dysfunction [ 1 ]. Diabetes Mellitus (DM) is a chronic disease characterized by disorders of carbohydrate, fat, and protein …
Glucocorticoid-induced diabetes represents an important yet often overlooked complication of GC therapy. Review the current knowledge on the mechanisms, prevalence, and risk factors in patients with autoimmune rheumatic diseases.
Obesity-related heart failure with preserved ejection fraction is increasingly recognized as a multiorgan cardio-renal-hepatic-metabolic syndrome but is not adequately addressed by conventional HF therapies. Is it time to rethink our approach?
The first of three podcast episodes on the identification and management of heart failure in people with diabetes, with practical guidance from a cardiovascular specialist, an endocrinologist, and a primary care physician.
FOH is an unsurprising occurrence in youth with type 1 diabetes and their caregivers, and can be a barrier to optimal self-management. This review provides an update of the FOH literature published from 2016 to 2025 for this population.