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Clinical Collections
Women’s Health Knowledge Hub Advances in Alzheimer’s

Navigating neuroimaging in Alzheimer disease care

PET imaging is playing an increasingly critical role in managing AD, but how can you effectively integrate it into clinical practice? Our expert-led program will empower you with practical strategies and real-world case studies.

This content is intended for healthcare professionals outside of the UK.
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Internal Medicine Diabetology

Diabetology

Long-term benefits for islet transplantation in type 1 diabetes

Islet transplantation alone significantly reduces the long-term risk for death and islet-after-kidney transplantation significantly reduces the long-term risk for dialysis in people with type 1 diabetes.

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Editor's Choice

Disordered sleep and painful diabetic neuropathy

Pain symptoms from PDN can disrupt sleep, and disordered sleep can exacerbate pain. Learn about promising treatments for disordered sleep in people with PDN and the efficacy of treatments in improving pain and/or sleep quality.

YKL-40 linked to GI cancer risk in type 2 diabetes

Raised YKL-40 levels are associated with an increased risk for obesity-related and gastrointestinal cancers, particularly liver cancer, in people with type 2 diabetes.

Skin infection or lymphoma in a woman with type 2 diabetes?

Cutaneous lymphoma should be considered in patients with long-standing, poorly controlled type 2 diabetes and chronic non-healing skin lesions. In this case, primary cutaneous B-cell lymphoma was misdiagnosed as a skin infection.

The threat of childhood obesity

Childhood obesity is a growing global health concern, but how should obesity be defined and measured in children, and how does it impact health in the short and long term?

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Keynote series | Spotlight on managing health in obesity

Obesity is a major contributor to cardiorenal metabolic disease, but its impact extends throughout the body. Understand how obesity can affect other organ systems and impact treatment, and whether weight-loss measures improve outcomes.

Prof. Eva L. Feldman
Prof. Jonette Keri
Developed by: Springer Medicine
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Video

Latest News

Long-term benefits for islet transplantation in type 1 diabetes

YKL-40 linked to GI cancer risk in type 2 diabetes

GLP-1 RAs may reduce dementia risk

GLP-1 RA plus thiazolidinedione has CV benefits in type 2 diabetes

Dulaglutide to tirzepatide switch outperforms dulaglutide escalation for type 2 diabetes control

STRIDEs made for type 2 diabetes plus peripheral artery disease

Using CGM to optimize type 2 diabetes management with non-intensive insulin treatment in primary care

With the growing importance of primary care in diabetes, this podcast discusses the evidence on continuous glucose monitoring (CGM) use, the role of primary healthcare, and practical tips for interpreting the ambulatory glucose profile (AGP) report. 

Supported by:
  • Abbott Diabetes Care
Prof. Samuel Seidu
Developed by: Adis
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Podcast

Case Studies

Skin infection or lymphoma in a woman with type 2 diabetes?

Cutaneous lymphoma should be considered in patients with long-standing, poorly controlled type 2 diabetes and chronic non-healing skin lesions. In this case, primary cutaneous B-cell lymphoma was misdiagnosed as a skin infection.

Colonic ischemia associated with a GLP-1 RA

Although it seems to be a rare complication, there should be a high index of suspicion for colonic ischemia in patients taking a GLP-1 receptor agonist who present with abdominal pain.

Non-islet cell tumor hypoglycemia and sarcoma

NICTH was diagnosed in a man with pelvic sarcoma. Severe hypoglycemia did not respond to standard treatments but had a partial response to rhGH and angioembolization of the tumor.

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
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Current Reviews

Retinal Ischemic Perivascular Lesions (RIPLs) as Potential Biomarkers for Systemic Vascular Diseases: A Narrative Review of the Literature

Retinal ischemic perivascular lesions (RIPLs) are characteristic focal thinning of the inner nuclear layer, with an upward expansion of the outer nuclear layer identified by spectral domain optical coherence tomography (SD-OCT), causing a focal …

Linking Hyperuricemia to Cancer: Emerging Evidence on Risk and Progression

Metabolic diseases posed a significant global burden in 2021, with reported cases including 226 million individuals with hypertension, 129 million with obesity, 88 million with hypercholesterolemia, 75 million with type 2 diabetes mellitus (T2DM) …

Managing diabetic cardiomyopathy without drugs

Treating cardiac dysfunction in diabetic cardiomyopathy remains challenging. Without useful drug therapies, are exercise and dietary strategies the best way to manage cardiac outcomes in DCM patients?

Dose-dependent effects of omega-3 polyunsaturated fatty acids on C-reactive protein concentrations in cardiometabolic disorders: a dose–response meta-analysis of randomized clinical trials

C-reactive protein (CRP) has been shown to be one of the top biomarkers for predicting future primary and secondary cardiovascular events and is one of the most studied biomarkers (Arroyo-Espliguero et al. 2021 ; van Holten et al. 2013 ). The …

Episode 10: Disease-modifying therapy for type 1 diabetes

Reducing the burden of type 1 diabetes

Despite many recent advances in its management, type 1 diabetes remains a burden for those living with the condition.

Prof. Chantal Mathieu explains the progress being made with disease-modifying therapy for type 1 diabetes and how it has the potential to transform the current treatment landscape.

Prof. Chantal Mathieu
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Podcast

Most Viewed in Diabetes and Obesity

Clinical use of polygenic scores in type 2 diabetes

GLP-1 RAs may reduce dementia risk

GLP-1 RA plus thiazolidinedione has CV benefits in type 2 diabetes

Focus on insulin icodec

At a glance: The STEP trials

Personalized dapagliflozin needed for type 2 diabetes and CKD

Editor's Choice | Diabetology Journals

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CME & eLearning

Videos | Case Scenarios | Infographics (Link opens in a new window)

1.0 AMA PRA Category 1 Credit(s)™

Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Vodcasts | Case Scenarios (Link opens in a new window)

Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

News | Expert Reviews | Cases (Link opens in a new window)

Treating children with hormone disorders is complex and requires tailored management. To help you provide the most effective care, we deliver resources covering adrenal, thyroid, pituitary, growth, and puberty disorders, obesity, and diabetes.

Supported by:
  • Merck Healthcare KGaA, Darmstadt, Germany
Developed by: Springer Healthcare IME

Further Reading

Retinal Ischemic Perivascular Lesions (RIPLs) as Potential Biomarkers for Systemic Vascular Diseases: A Narrative Review of the Literature

Retinal ischemic perivascular lesions (RIPLs) are characteristic focal thinning of the inner nuclear layer, with an upward expansion of the outer nuclear layer identified by spectral domain optical coherence tomography (SD-OCT), causing a focal …

Pancreatic exocrine damage induces beta cell stress in zebrafish larvae

  • Open Access
  • Insulins
  • Original Research

The pancreas is one organ with two major distinct functions, namely physiological regulated exocrine and endocrine secretion. The integrated infrastructure underscores the coherence between the islets of Langerhans and exocrine cells, which is …

Dysregulated skeletal muscle myosin super-relaxation and energetics in male participants with type 2 diabetes mellitus

As a major tissue in the regulation of whole-body glycaemic control, skeletal muscle has long been established as critical to the onset of type 2 diabetes mellitus [ 1 ]. While decades of research have advanced our molecular understanding of how …

Testosterone Therapy in Older Men: Present and Future Considerations

Testosterone is the classical male anabolic hormone, involved in sexual development, virilisation and regulation of body composition in adult men. Organic disease involving the hypothalamus, pituitary or testes may interfere with endogenous …

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