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Diabetologia

Issue 6/2025

Content (23 Articles)

Up Front

Exploring the shared genetic landscape of diabetes and cardiovascular disease: findings and future implications

Hyunsuk Lee, Maria Fernandes, Jeongeun Lee, Jordi Merino, Soo Heon Kwak

The efficacy of islet autoantibody screening with or without genetic pre-screening strategies for the identification of presymptomatic type 1 diabetes

Ezio Bonifacio, Raquel Coelho, Domenik A. Ewald, Gita Gemulla, Michael Hubmann, Przemyslawa Jarosz-Chobot, Mirjam Kohls, Olga Kordonouri, Vito Lampasona, Parth Narendran, Flemming Pociot, Zdenek Šumník, Agnieszka Szypowska, Jose Zapardiel-Gonzalo, Anette-Gabriele Ziegler

Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes affirms markers of disease

Robert Moulder, M. Karoliina Hirvonen, Tommi Välikangas, Tomi Suomi, Lut Overbergh, Mark Peakman, Søren Brunak, Chantal Mathieu, Mikael Knip, Laura L. Elo, Riitta Lahesmaa

Early weight loss, diabetes remission and long-term trajectory after diagnosis of type 2 diabetes: a retrospective study

Mario Luca Morieri, Mauro Rigato, Vera Frison, Michele D’Ambrosio, Giovanni Sartore, Angelo Avogaro, Gian Paolo Fadini

Cardiac arrhythmia and hypoglycaemia among individuals with and without diabetes receiving haemodialysis (the CADDY study): a Danish multicentre cohort study

Dea H. Kofod, Søren Z. Diederichsen, Tobias Bomholt, Mads Ø. Andersen, Andreas Andersen, Ebba Mannheimer, Marianne Rix, Ylian S. Liem, Kristine Lindhard, Henrik P. Hansen, Casper Rydahl, Morten Lindhardt, Julie Brøsen, Kristine Schandorff, Theis Lange, Kirsten Nørgaard, Thomas P. Almdal, Jesper H. Svendsen, Bo Feldt-Rasmussen, Mads Hornum

Macular perfusion alterations in people with recent-onset diabetes and novel diabetes subtypes

Sema Kaya, Ala Khamees, Gerd Geerling, Piotr Strzalkowski, Veronika Gontscharuk, Julia Szendroedi, Karsten Müssig, Dan Ziegler, Michael Roden, Rainer Guthoff

A simple score-based strategy to improve equity of the UK biennial diabetic eye screening protocol among people deemed as low risk

Matilda Pitt, Abraham Olvera-Barrios, John Anderson, Louis Bolter, Ryan Chambers, Alasdair N. Warwick, Samantha Mann, Laura Webster, Jiri Fajtl, Sarah A. Barman, Catherine Egan, Adnan Tufail, Alicja R. Rudnicka, Christopher G. Owen

TBC1D30 regulates proinsulin and insulin secretion and is the target of a genomic association signal for proinsulin

Victoria A. Parsons, Swarooparani Vadlamudi, Kayleigh M. Voos, Abigail E. Rohy, Anne H. Moxley, Maren E. Cannon, Jonathan D. Rosen, Christine A. Mills, Laura E. Herring, K. Alaine Broadaway, Damaris N. Lorenzo, Karen L. Mohlke

Genome-wide association study identifying novel risk variants associated with glycaemic traits in the continental African AWI-Gen cohort

Vivien J. Chebii, Alisha N. Wade, Nigel J. Crowther, Engelbert A. Nonterah, Godfred Agongo, Z. Simayi, Palwende R. Boua, Isaac Kisiangani, Michèle Ramsay, Ananyo Choudhury, Dhriti Sengupta

Enterovirus VP1 protein and HLA class I hyperexpression in pancreatic islet cells of organ donors with type 1 diabetes

Teresa Rodriguez-Calvo, Jutta E. Laiho, Maarit Oikarinen, Pouria Akhbari, Christine Flaxman, Thomas Worthington, Paola Apaolaza, John S. Kaddis, Irina Kusmartseva, Sisko Tauriainen, Martha Campbell-Thompson, Mark A. Atkinson, Matthias von Herrath, Heikki Hyöty, Noel G. Morgan, Alberto Pugliese, Sarah J. Richardson

Detection of enterovirus RNA in pancreas and lymphoid tissues of organ donors with type 1 diabetes

Jutta E. Laiho, Sami Oikarinen, Sofia Morfopoulou, Maarit Oikarinen, Ashlie Renner, Daniel Depledge, Matthew C. Ross, Ivan C. Gerling, Judith Breuer, Joseph F. Petrosino, Vincent Plagnol, Alberto Pugliese, Antonio Toniolo, Richard E. Lloyd, Heikki Hyöty

Joint analysis of the nPOD-Virus Group data: the association of enterovirus with type 1 diabetes is supported by multiple markers of infection in pancreas tissue

Sarah J. Richardson, Teresa Rodriguez-Calvo, Jutta E. Laiho, John S. Kaddis, Julius O. Nyalwidhe, Irina Kusmartseva, Sofia Morfopoulou, Joseph F. Petrosino, Vincent Plagnol, Kathrin Maedler, Margaret A. Morris, Jerry L. Nadler, Mark A. Atkinson, Matthias von Herrath, Richard E. Lloyd, Heikki Hyoty, Noel G. Morgan, Alberto Pugliese

Intrapancreatic adipocytes and beta cell dedifferentiation in human type 2 diabetes

Na Zhang, Qiman Sun, Jiaxin Zhang, Ruonan Zhang, Siyi Liu, Xuelian Zhao, Jing Ma, Xiaomu Li

Comprehensive sequencing profile and functional analysis of IsomiRs in human pancreatic islets and beta cells

Stefano Auddino, Elena Aiello, Giuseppina E. Grieco, Daniela Fignani, Giada Licata, Marco Bruttini, Alessia Mori, Andrea F. Berteramo, Erika Pedace, Laura Nigi, Caterina Formichi, Claudiane Guay, Giuseppe Quero, Vincenzo Tondolo, Gianfranco Di Giuseppe, Laura Soldovieri, Gea Ciccarelli, Andrea Mari, Andrea Giaccari, Teresa Mezza, Agnese Po, Romano Regazzi, Francesco Dotta, Guido Sebastiani

Regulating islet stress responses through CD47 activation

Atharva Kale, Mahmoud Azar, Vanessa Cheng, Harry Robertson, Sally Coulter, Paulomi M. Mehta, Sohel M. Julovi, Ellis Patrick, Kedar Ghimire, Natasha M. Rogers

Parent-of-origin effects in the life-course evolution of cardiometabolic traits

Rucha Wagh, Gad Hatem, Jonas Andersson, Pooja Kunte, Souvik Bandyopadhyay, Chittaranjan S. Yajnik, Rashmi B. Prasad

Alterations in cerebral perfusion and substrate metabolism in type 2 diabetes: interactions with APOE-ε4

Martin Schain, Edvin Johansson, Iina Laitinen, Anna Frödén Löwenmark, Mark Lubberink, Anders Gummesson, Torsten Danfors, Pirjo Nuutila, Russell Esterline, Lars Johansson, Jan Oscarsson, Kerstin Heurling

Metformin therapy modifies corneal neuroimmune abnormalities in people with type 2 diabetes

Amy T. Tsoi, Janice Sng, Shyam S. Tummanapalli, Tushar Issar, Ann M. Poynten, Kerry-Lee Milner, Maria Markoulli, Roshan Dhanapalaratnam, Arun V. Krishnan

MAP4K4 aggravates microvascular anomalies in diabetic retinopathy in a YTHDF2-dependent manner

Qian Yang, Pei-wen Zhu, Yan-jun Wen, Ran Zhang, Wen-wen Chen, Xin Huang, Qing Chang

The genetic architecture of type 1 diabetes over time: how well can we rely on past data to predict the future?

Jose Zapardiel-Gonzalo, Anette-Gabriele Ziegler, Ezio Bonifacio

Quinine: rediscovery of an old glucose-lowering drug

Jean-Claude Henquin

Quinine: rediscovery of an old glucose-lowering drug. Reply to Henquin J-C [letter]

Javad Anjom-Shoae, Michael Horowitz, Christine Feinle-Bisset

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