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Use of thermal imaging in the detection of the diabetic foot- review

Abstract

Diabetic foot ulcers (DFUs) are among the most serious complications of diabetes mellitus, often resulting in infection, amputation, and increased mortality. Early detection is essential but remains difficult due to the complex interaction of neuropathy, vascular disease, and immune dysfunction. This review examines the effectiveness of thermal imaging, including approaches supported by artificial intelligence (AI), as a non-invasive tool for identifying early signs of DFUs. A total of 49 studies published between 1991 and 2024 were analysed, focusing on adult patients and primary research only. Findings show that thermal imaging can detect abnormal skin temperature patterns and early inflammation, key indicators of DFU development. AI techniques, such as machine learning and neural networks, further enhance diagnostic accuracy by identifying subtle patterns and predicting ulcer risk. Despite promising results, several limitations were noted: lack of standardised imaging protocols, inconsistent equipment quality, and small sample sizes in many studies. To improve clinical reliability, future work should focus on developing standard procedures, integrating AI with high-resolution thermal cameras, and validating these systems in real-world hospital and home-care settings. Overall, thermal imaging, especially when combined with AI, shows strong potential as a practical, non-invasive method for early DFU detection and monitoring.
Title
Use of thermal imaging in the detection of the diabetic foot- review
Authors
Aleksandra Mrowiec
Teresa Kasprzyk-Kucewicz
Daria Wziątek-Kuczmik
Agata Stanek
Armand Cholewka
Publication date
14-10-2025
Publisher
Springer US
Published in
Reviews in Endocrine and Metabolic Disorders
Print ISSN: 1389-9155
Electronic ISSN: 1573-2606
DOI
https://doi.org/10.1007/s11154-025-09999-w
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Image Credits
Thermal plantar foot images of a person with diabetes/© (M) 2024, N Christy Evangeline et al. in Big Data, Machine Learning, and Applications. BigDML 2021. Lecture Notes in Electrical Engineering, under exclusive license to Springer Nature Singapore Pte Ltd., Woman monitoring glucose level with sensor and an app on her phone while training at swimming pool/© (M) Goffkein, stock.adobe.com (symbolic image with model), Person walking/© _KUBE_ / Stock.adobe.com