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Diabetology Diabetes Therapy

Diabetes Therapy

Open Access Diabetes-associated Diseases Case Study

Necrotizing myopathy in a woman with type 1 diabetes

Identifying the cause of muscle necrosis can be a diagnostic challenge, as shown by this case of diabetic myonecrosis complicated by pyomyositis and abscess caused by Escherichia coli.

Editor's Choice

Immune checkpoint inhibitor-induced diabetes

Free for a limited time Other Specific Types of Diabetes Review

ICIs have advanced cancer treatment but can trigger immune-related adverse events. Explore the pathogenesis, progression, and treatment strategies for ICI-induced diabetes.

Fixed-ratio combinations for glycemic control

Open Access Diabetes Therapy Expert Opinion

How might fixed-ratio combinations of basal insulins and GLP-1 receptor agonists be used to optimize treatment of type 2 diabetes? Find out more in this expert opinion paper.

Managing type 2 diabetes and lower extremity PAD

Open Access Type 2 Diabetes Review

GLP-1 receptor agonists and SGLT2 inhibitors have demonstrated cardiovascular benefits, but where do they fit in the management of individuals who have type 2 diabetes and peripheral artery disease?

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Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Using CGM to optimize type 2 diabetes management with non-intensive insulin treatment in primary care

With the growing importance of primary care in diabetes, this podcast discusses the evidence on continuous glucose monitoring (CGM) use, the role of primary healthcare, and practical tips for interpreting the ambulatory glucose profile (AGP) report. 

Supported by: Abbott Diabetes Care

Prof. Samuel Seidu
Developed by: Adis

Case Studies

Necrotizing myopathy in a woman with type 1 diabetes

Open Access Diabetes-associated Diseases Case Study

Identifying the cause of muscle necrosis can be a diagnostic challenge, as shown by this case of diabetic myonecrosis complicated by pyomyositis and abscess caused by Escherichia coli.

Abnormal glycated hemoglobin level in a patient with diabetes

Open Access Type 2 Diabetes Case Study

HbA1c levels that don’t match the clinical picture need further investigation. Other factors, such as Hb variants, can interfere with the HbA1c measurement and make glycemic control difficult to achieve.

Overlooked effect of angiotensin receptor–neprilysin inhibitor

Caution is needed when assessing insulin secretion capability and nephropathy in patients with diabetes who are being treated with an angiotensin receptor–neprilysin inhibitor.

Episode 10: Disease-modifying therapy for type 1 diabetes

Reducing the burden of type 1 diabetes

Despite many recent advances in its management, type 1 diabetes remains a burden for those living with the condition.

Prof. Chantal Mathieu explains the progress being made with disease-modifying therapy for type 1 diabetes and how it has the potential to transform the current treatment landscape.

Prof. Chantal Mathieu

Current Reviews

Safety and Psychological Outcomes of Tandem t:Slim X2 Insulin Pump with Control-IQ Technology in Children, Adolescents, and Young Adults with Type 1 Diabetes: A Systematic Review

Open Access Type 1 Diabetes Review

The Tandem t:slim X2 insulin pump is a second-generation automated insulin delivery system with Control-IQ technology. It consists of an X2 insulin pump, an integrated Dexcom sensor, and an embedded ‘Control-IQ’ algorithm, which predicts glucose …

Advances in diabetes technology to improve the lives of people with cystic fibrosis

People with cystic fibrosis (CF) are at risk for dysglycaemia caused by progressive beta cell dysfunction and destruction due to pancreatic exocrine disease and fibrosis. CF-related diabetes (CFRD) is a unique form of diabetes that has distinctive …

Use of diabetes technology in children

Open Access Type 1 Diabetes Review

Children with type 1 diabetes and their caregivers face numerous challenges navigating the unpredictability of this complex disease. Although the burden of managing diabetes remains significant, new technology has eased some of the load and …

Modern Management of Cardiometabolic Continuum: From Overweight/Obesity to Prediabetes/Type 2 Diabetes Mellitus. Recommendations from the Eastern and Southern Europe Diabetes and Obesity Expert Group

Open Access Type 2 Diabetes Review

The increasing global incidence of obesity and type 2 diabetes mellitus (T2D) underscores the urgency of addressing these interconnected health challenges. Obesity enhances genetic and environmental influences on T2D, being not only a primary risk …

Insulins Clinical Trial Summary

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.

Developed by: Springer Medicine

CME & eLearning

Videos | Case Scenarios | Infographics (Link opens in a new window)

1.0 AMA PRA Category 1 Credit(s)

Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Tweetorials | Vodcasts | Infographics (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)

Stay up to date with the rapidly changing CGM landscape. Learn how to implement and integrate CGM into diabetes management to improve patient care and outcomes.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Vodcasts | Case Scenarios (Link opens in a new window)

Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Further Reading

Tirzepatide Improved Health-Related Quality of Life Compared with Insulin Lispro in Basal Insulin-Treated Adults with Type 2 Diabetes and Inadequate Glycaemic Control: A Randomised Controlled Phase 3b Trial (SURPASS-6)

Open Access Tirzepatide Original Research

Type 2 diabetes (T2D) is characterised by insulin resistance and progressive loss of beta cell function [ 1 ]. Patients with long-standing inadequately controlled diabetes often require initiation of insulin therapy, usually with basal insulin.

Association of Changes in A1C Following Continuous Glucose Monitoring Acquisition in People with Sub-Optimally Treated Type 2 Diabetes Taking GLP-1 RA Therapy

Open Access Type 2 Diabetes Original Research

A target A1c of < 7% is the recommended goal for many people with type 2 diabetes (T2D) [ 1 ]; however, the National Committee for Quality Assurance has set A1c < 8% as their limit for control [ 2 ]. Nevertheless, many are not achieving either …

The Elusive Nature of ABCC8-related Maturity-Onset Diabetes of the Young (ABCC8-MODY). A Review of the Literature and Case Discussion

Maturity-Onset Diabetes of the Young (MODY) is an heterogenous group of monogenic forms of diabetes mellitus caused by genetic defects mainly leading to the secretory dysfunction of pancreatic β-cells [ 1 ]. MODY is a rare condition, accounting for …

Mitochondrial Adaptation in Skeletal Muscle: Impact of Obesity, Caloric Restriction, and Dietary Compounds

Open Access Obesity REVIEW

In the era of convenience and abundance of ultra-processed foods, the Western diet has become embedded in our current society. Despite its popularity, the Western diet has been recognized as the major culprit of a more pressing matter – the global …