Published in:

19-07-2024 | Dementia | REVIEW

Health Behavior Change to Mitigate Dementia Risk: An Updated Review

Authors: Victoria Sanborn, Jennifer D. Davis, Laura E. Korthauer

Published in: Current Geriatrics Reports | Issue 3/2024

Abstract

Significance

Over the past two decades, we have become increasingly aware of the impact of health behaviors on risk for dementia and, more specifically, Alzheimer’s disease. This concept was stressed in the 2020 Report of the Lancet Commission, which demonstrated that up to 40% of dementia cases could be mitigated by behavior change alone. Though there are several psychosocial and health factors associated with increased risk for Alzheimer’s disease, health behaviors that appear particularly worthwhile for reducing risk include adherence to healthy diet, remaining physically active, and engaging in cognitively stimulating endeavors.

Objective

The present review provides a general summary of what has been learned from observational and controlled studies examining the roles of these behaviors on cognitive outcomes, including risk for Alzheimer’s disease.

Findings

Though this line of research has largely confirmed the importance of integrating health behaviors to promote cognitive outcomes, some constraints inherent to intervention research (i.e., time restrictions, variable adherence, reduced generalizability) have limited conclusions. As such, many questions regarding the impact of health behaviors on Alzheimer’s disease risk remain.

Conclusions

Future research on these topics should integrate tailored interventions that consider individual factors that appear to impact the effectiveness of health behavior change on dementia risk (i.e., age, sex, culture, access to resources) and influence engagement in health behaviors during and after interventions (i.e., health beliefs).

American Psychiatric Association. Diagnostic and statistical manual of mental disorders (5th ed.). 2013. https://doi.org/10.1176/appi.books.9780890425596.

Gustavsson A, Norton N, Fast T, Frölich L, Georges J, Holzapfel D, Kirabali T, Krolak-Salmon P, Rossini PM, Ferretti MT, Lanman L. Global estimates on the number of persons across the Alzheimer’s disease continuum. Alzheimers Dement. 2023;19(2):658–70. https://doi.org/10.1002/alz.12694.CrossRefPubMed

Alzheimer’s Association. 2024 alzheimer’s disease facts and figures. Alzheimers Dement 2024;20(5).

Collaborators D. The burden of dementia due to down syndrome, Parkinson’s disease, stroke, and traumatic brain Injury: A systematic analysis for the global burden of disease study 2019. Neuroepidemiology. 2021;55(4):286–96. https://doi.org/10.1159/000515393.CrossRef

Spina S, La Joie R, Petersen C, Nolan AL, Cuevas D, Cosme C, Hepker M, Hwang JH, Miller ZA, Huang EJ, Karydas AM. Comorbid neuropathological diagnoses in early versus late-onset Alzheimer’s disease. Brain. 2021;144(7):2186–98. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502474/.CrossRefPubMedPubMedCentral

Villemagne VL, Burnham S, Bourgeat P, Brown B, Ellis KA, Salvado O, Szoeke C, Macaulay SL, Martins R, Maruff P, Ames D. Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer’s disease: A prospective cohort study. The Lancet Neurol. 2013;12(4):357–67. https://doi.org/10.1016/S1474-4422(13)70044-9.CrossRefPubMed

Livingston G, Huntley J, Sommerlad A, Ames D, Ballard C, Banerjee S, Brayne C, Burns A, Cohen-Mansfield J, Cooper C, Costafreda SG. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet. 2020;396(10248):413–46. https://doi.org/10.1016/S0140-6736(20)30367-6.CrossRefPubMedPubMedCentral

Manes F, Gleichgerrcht E. Language, memory and the temporal lobes. Behav Neurol. 2011;24(4):263–4. https://doi.org/10.3233/BEN-2011-0336.CrossRefPubMedPubMedCentral

de Flores R, Das SR, Xie L, Wisse LE, Lyu X, Shah P, Yushkevich PA, Wolk DA. Medial temporal lobe networks in Alzheimer’s disease: Structural and molecular vulnerabilities. J Neurosci. 2022;42(10):2131–41. https://doi.org/10.1523/JNEUROSCI.0949-21.2021.CrossRefPubMedPubMedCentral

10.

Pettigrew C, Soldan A, Sloane K, Cai Q, Wang J, Wang MC, Moghekar A, Miller MI, Albert M, BIOCARD Research Team. Progressive medial temporal lobe atrophy during preclinical Alzheimer’s disease. NeuroImage Clin. 2017;16:439–46. https://doi.org/10.1016/j.nicl.2017.08.022.CrossRefPubMedPubMedCentral

11.

Chojdak-Łukasiewicz J, Dziadkowiak E, Zimny A, Paradowski B. Cerebral small vessel disease: A review. Adv Clin and Exp Med. 2021;30(3):349–56. https://doi.org/10.17219/acem/131216.CrossRef

12.

Guzik A, Bushnell C. Stroke epidemiology and risk factor management. Continuum. 2017;23(1):15–39. https://journals.lww.com/continuum/abstract/2017/02000/stroke_epidemiology_and_risk_factor_management.7.aspx.PubMed

13.

Solfrizzi V, Custodero C, Lozupone M, Imbimbo BP, Valiani V, Agosti P, Schilardi A, D’Introno A, La Montagna M, Calvani M, Guerra V. Relationships of dietary patterns, foods, and micro-and macronutrients with Alzheimer’s disease and late-life cognitive disorders: A systematic review. J Alzheimer’s Dis. 2017;59(3):815–49. https://doi.org/10.3233/JAD-170248.CrossRef

14.

Tangney CC, Li H, Wang Y, Barnes L, Schneider JA, Bennett DA, Morris MC. Relation of DASH-and Mediterranean-like dietary patterns to cognitive decline in older persons. Neurology. 2014;83(16):1410–6. https://doi.org/10.1212/WNL.0000000000000884.CrossRefPubMedPubMedCentral

15.

Morris MC, Tangney CC, Wang Y, Sacks FM, Bennett DA, Aggarwal NT. MIND diet associated with reduced incidence of Alzheimer’s disease. Alzheimers Demen. 2015;11(9):1007–14. https://doi.org/10.1016/j.jalz.2014.11.009.CrossRef

16.

Solch RJ, Aigbogun JO, Voyiadjis AG, Talkington GM, Darensbourg RM, O’Connell S, Pickett KM, Perez SR, Maraganore DM. Mediterranean diet adherence, gut microbiota, and Alzheimer’s or Parkinson’s disease risk: A systematic review. J Neurol Sci. 2022;15(434):120166. https://doi.org/10.1016/j.jns.2022.120166.CrossRef

17.

Misirli G, Benetou V, Lagiou P, Bamia C, Trichopoulos D, Trichopoulou A. Relation of the traditional Mediterranean diet to cerebrovascular disease in a Mediterranean population. Am J Epidemiol. 2012;176(12):1185–92. https://doi.org/10.1093/aje/kws205.CrossRefPubMed

18.

Soltani S, Arablou T, Jayedi A, Salehi-Abargouei A. Adherence to the dietary approaches to stop hypertension (DASH) diet in relation to all-cause and cause-specific mortality: A systematic review and dose-response meta-analysis of prospective cohort studies. Nutr J. 2020;19:1–3. https://doi.org/10.1186/s12937-020-00554-8.CrossRef

19.

Morris MC, Tangney CC, Wang Y, Sacks FM, Barnes LL, Bennett DA, Aggarwal NT. MIND diet slows cognitive decline with aging. Alzheimers Dement. 2015;11(9):1015–22. https://doi.org/10.1016/j.jalz.2015.04.011.CrossRefPubMed

20.

Cherian L, Wang Y, Fakuda K, Leurgans S, Aggarwal N, Morris M. Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) diet slows cognitive decline after stroke. J Prev Alzheimers Dis. 2019;6:267–73. https://doi.org/10.14283/jpad.2019.28.CrossRefPubMedPubMedCentral

21.

Mosconi L, Murray J, Tsui WH, Li Y, Davies M, Williams S, Pirraglia E, Spector N, Osorio RS, Glodzik L, McHugh P. Mediterranean diet and magnetic resonance imaging-assessed brain atrophy in cognitively normal individuals at risk for Alzheimer’s disease. J Prev Alzheimers Dis. 2014;1(1):23.PubMedPubMedCentral

22.

Berti V, Murray J, Davies M, Spector N, Tsui WH, Li Y, Williams S, Pirraglia E, Vallabhajosula S, McHugh P, Pupi AD. Nutrient patterns and brain biomarkers of Alzheimer’s disease in cognitively normal individuals. J Nutr Health Aging. 2015;19:413–23. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375781/.CrossRefPubMedPubMedCentral

23.

Hill E, Goodwill AM, Gorelik A, Szoeke C. Diet and biomarkers of Alzheimer’s disease: A systematic review and meta-analysis. Neurobiol Aging. 2019;76:45–52. https://doi.org/10.1016/j.neurobiolaging.2018.12.008.CrossRefPubMed

24.

Vuori I. World Health Organization and physical activity. Prog Prev Med. 2018;3(1):e0012. https://doi.org/10.1097/pp9.0000000000000012.CrossRef

25.

Lopez-Ortiz S, Lista S, Valenzuela PL, Pinto-Fraga J, Carmona R, Caraci F, Caruso G, Toschi N, Emanuele E, Gabelle A, Nistico R. Effects of physical activity and exercise interventions on Alzheimer’s disease: An umbrella review of existing meta-analyses. J Neurol. 2023;270(2):711–25. https://doi.org/10.1007/s00415-022-11454-8.CrossRefPubMed

26.

Santos-Lozano A, Pareja-Galeano H, Sanchis-Gomar F, Quindós-Rubial M, Fiuza-Luces C, Cristi-Montero C, Emanuele E, Garatachea N, Lucia A. Physical activity and Alzheimer disease: A protective association. Mayo Clin Proc. 2016;91(8):999–1020. https://doi.org/10.1016/j.mayocp.2016.04.024.CrossRefPubMed

27.

Lee J. The relationship between physical activity and dementia: A systematic review and meta-analysis of prospective cohort studies. J Gerontol Nurs. 2018;44(10):22–9.CrossRefPubMed

28.

Iso-Markku P, Kujala UM, Knittle K, Polet J, Vuoksimaa E, Waller K. Physical activity as a protective factor for dementia and Alzheimer’s disease: Systematic review, meta-analysis and quality assessment of cohort and case–control studies. Br J Sports Med. 2022;56(12):701–9. https://bjsm.bmj.com/content/56/12/701?fbclid=IwAR1tz1zgsl3wpfepEoMfuyPdrVQ1Q1R1kJW-bEkYEqD_wkP4lfS9O169Oxo.CrossRefPubMed

29.

Huang SY, Li YZ, Zhang YR, Huang YY, Wu BS, Zhang W, Deng YT, Chen SD, He XY, Chen SF, Dong Q. Sleep, physical activity, sedentary behavior, and risk of incident dementia: A prospective cohort study of 431,924 UK Biobank participants. Mol Psychiatry. 2022;27(10):4343–54. https://www.nature.com/articles/s41380-022-01655-y.CrossRefPubMed

30.

Elgaddal N, Kramarow EA, Reuben C, National Center for Health Statistics. Physical activity among adults aged 18 and over: United States, 2020. NCHS Data Brief. 2022;443:1–8. https://doi.org/10.15620/cdc:120213.CrossRef

31.

Lopes S, Mesquita-Bastos J, Garcia C, Bertoquini S, Ribau V, Teixeira M, Ribeiro IP, Melo JB, Oliveira J, Figueiredo D, Guimaraes GV. Effect of exercise training on ambulatory blood pressure among patients with resistant hypertension: A randomized clinical trial. JAMA Cardiol. 2021;6(11):1317–23. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340008/.CrossRefPubMed

32.

Edwards KM, Ziegler MG, Mills PJ. The potential anti-inflammatory benefits of improving physical fitness in hypertension. J Hypertens. 2007;25(8):1533–42. https://doi.org/10.1097/HJH.0b013e328165ca67.CrossRefPubMed

33.

Aune D, Norat T, Leitzmann M, Tonstad S, Vatten LJ. Physical activity and the risk of type 2 diabetes: A systematic review and dose–response meta-analysis. Eur J epidemiol. 2015;30:529–42. https://doi.org/10.1007/s10654-015-0056-z.CrossRefPubMed

34.

Cárdenas Fuentes G, Bawaked RA, Martínez González MÁ, Corella D, Subirana Cachinero I, Salas-Salvadó J, Estruch R, Serra-Majem L, Ros E, Lapetra Peralta J, Fiol M. Association of physical activity with body mass index, waist circumference and incidence of obesity in older adults. Eur J Public Health. 2018;28(5):944–50. https://academic.oup.com/eurpub/article/28/5/944/4938725?login=false.CrossRefPubMed

35.

Cleven L, Krell-Roesch J, Nigg CR, Woll A. The association between physical activity with incident obesity, coronary heart disease, diabetes and hypertension in adults: A systematic review of longitudinal studies published after 2012. BMC Public Health. 2020;20(1):1–5. https://doi.org/10.1186/s12889-020-08715-4.CrossRef

36.

Haeger A, Costa AS, Schulz JB, Reetz K. Cerebral changes improved by physical activity during cognitive decline: A systematic review on MRI studies. NeuroImage Clin. 2019;23:101933. https://doi.org/10.1016/j.nicl.2019.101933.CrossRefPubMedPubMedCentral

37.

Hüttenrauch M, Brauss A, Kurdakova A, Borgers H, Klinker F, Liebetanz D, Salinas-Riester G, Wiltfang J, Klafki HW, Wirths O. Physical activity delays hippocampal neurodegeneration and rescues memory deficits in an Alzheimer disease mouse model. Transl Psychiatry. 2016;6(5):e800. https://www.nature.com/articles/tp201665.CrossRefPubMedPubMedCentral

38.

Nokia MS, Lensu S, Ahtiainen JP, Johansson PP, Koch LG, Britton SL, Kainulainen H. Physical exercise increases adult hippocampal neurogenesis in male rats provided it is aerobic and sustained. J Physiol. 2016;594(7):1855–73. https://doi.org/10.1113/JP271552.CrossRefPubMedPubMedCentral

39.

Ruiz-Gonzalez D, Hernandez-Martinez A, Valenzuela PL, Morales JS, Soriano-Maldonado A. Effects of physical exercise on plasma brain-derived neurotrophic factor in neurodegenerative disorders: A systematic review and meta-analysis of randomized controlled trials. Neurosci Biobehav Rev. 2021;128:394–405. https://doi.org/10.1016/j.neubiorev.2021.05.025.CrossRefPubMed

40.

Rodriguez-Ayllon M, Solís-Urra P, Arroyo-Ávila C, Álvarez-Ortega M, Molina-García P, Molina-Hidalgo C, Gómez-Río M, Brown B, Erickson KI, Esteban-Cornejo I. Physical activity and amyloid beta in middle-aged and older adults: A systematic review and meta-analysis. J Sport Health Sci. 2023. https://doi.org/10.1016/j.jshs.2023.08.001.CrossRefPubMedPubMedCentral

41.

Krivanek TJ, Gale SA, McFeeley BM, Nicastri CM, Daffner KR. Promoting successful cognitive aging: A ten-year update. J Alzheimers Dis. 2021;81(3):871–920. https://content.iospress.com/articles/journal-of-alzheimers-disease/jad201462.CrossRefPubMedPubMedCentral

42.

Najar J, Östling S, Gudmundsson P, Sundh V, Johansson L, Kern S, Guo X, Hällström T, Skoog I. Cognitive and physical activity and dementia: A 44-year longitudinal population study of women. Neurology. 2019;92(12):e1322–30. https://doi.org/10.1212/WNL.0000000000007021.CrossRefPubMedPubMedCentral

43.

Su S, Shi L, Zheng Y, Sun Y, Huang X, Zhang A, Que J, Sun X, Shi J, Bao Y, Deng J. Leisure activities and the risk of dementia: A systematic review and meta-analysis. Neurology. 2022;99(15):e1651–63. https://doi.org/10.1212/WNL.0000000000200929.CrossRefPubMedPubMedCentral

44.

Martin-Bassols N, de New SC, Johnston DW, Shields MA. Cognitive activity at work and the risk of dementia. Health Econ. 2023. https://doi.org/10.1002/hec.4679.CrossRefPubMed

45.

Landau SM, Marks SM, Mormino EC, Rabinovici GD, Oh H, O’Neil JP, Wilson RS, Jagust WJ. Association of lifetime cognitive engagement and low β-amyloid deposition. Arch Neurol. 2012;69(5):623–9. https://jamanetwork.com/journals/jamaneurology/fullarticle/1149704.CrossRefPubMedPubMedCentral

46.

Reiter K, Butts AM, Janecek JK, Correro AN, Nencka A, Agarwal M, Franczak M, Glass Umfleet L. Relationship between cognitive reserve, brain volume, and neuropsychological performance in amnestic and nonamnestic MCI. Aging Neuropsychol Cogn. 2023;30(6):940–56. https://www.tandfonline.com/doi/abs/10.1080/13825585.2022.2161462.CrossRef

47.

Gidicsin CM, Maye JE, Locascio JJ, Pepin LC, Philiossaint M, Becker JA, Younger AP, Dekhtyar M, Schultz AP, Amariglio RE, Marshall GA. Cognitive activity relates to cognitive performance but not to Alzheimer disease biomarkers. Neurology. 2015;85(1):48–55. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501938/.CrossRefPubMedPubMedCentral

48.

Anthony M, Lin F. A systematic review for functional neuroimaging studies of cognitive reserve across the cognitive aging spectrum. Arch Clin Neuropsychol. 2018;33(8):937–48. https://academic.oup.com/acn/article/33/8/937/4734938.CrossRefPubMed

49.

Stern Y. What is cognitive reserve? Theory and research application of the reserve concept. J Inter Neuropsychol Soc. 2002;8(3):448–60. https://www.cambridge.org/core/journals/journal-of-the-international-neuropsychological-society/article/abs/what-is-cognitive-reserve-ory-and-research-application-of-the-reserve-concept/B6524DF8FC814A462004141F7B19BCF4.CrossRef

50.

Röhr S, Pabst A, Baber R, Engel C, Glaesmer H, Hinz A, Schroeter ML, Witte AV, Zeynalova S, Villringer A, Löffler M, Riedel-Heller SG. Social determinants and lifestyle factors for brain health: Implications for risk reduction of cognitive decline and dementia. Sci Rep. 2022;12(1):12965. https://doi.org/10.1038/s41598-022-16771-6.CrossRefPubMedPubMedCentral

51.

Valls-Pedret C, Sala-Vila A, Serra-Mir M, Corella D, de la Torre R, Martínez-González MÁ, Martínez-Lapiscina EH, Fitó M, Pérez-Heras A, Salas-Salvadó J, et al. Mediterranean diet and age-related cognitive decline: A randomized clinical trial. JAMA Intern Med. 2015;175:1094–103.CrossRefPubMed

52.

Barnes LL, Dhana K, Liu X, Carey VJ, Ventrelle J, Johnson K, Hollings CS, Bishop L, Laranjo N, Stubbs BJ, Reilly X. Trial of the MIND diet for prevention of cognitive decline in older persons. N Engl J Med. 2023;389(7):602–11. https://doi.org/10.1056/NEJMoa2302368.CrossRefPubMedPubMedCentral

53.

Arjmand G, Abbas-Zadeh M, Eftekhari MH. Effect of MIND diet intervention on cognitive performance and brain structure in healthy obese women: A randomized controlled trial. Sci Rep. 2022;12(1):2871. https://doi.org/10.1038/s41598-021-04258-9.CrossRefPubMedPubMedCentral

54.

Young J, Angevaren M, Rusted J, Tabet N. Aerobic exercise to improve cognitive function in older people without known cognitive impairment. Cochrane Database Syst Rev. 2015;(4). https://doi.org/10.1002/14651858.CD005381.pub4.

55.

Gallardo-Gómez D, del Pozo-Cruz J, Noetel M, Álvarez-Barbosa F, Alfonso-Rosa RM, del Pozo CB. Optimal dose and type of exercise to improve cognitive function in older adults: A systematic review and bayesian model-based network meta-analysis of RCTs. Ageing Res Rev. 2022;76:101591. https://doi.org/10.1016/j.arr.2022.101591.CrossRefPubMed

56.

Eckardt N, Braun C, Kibele A. Instability resistance training improves working memory, processing speed and response inhibition in healthy older Adults: A double-blinded randomised controlled trial. Sci Rep. 2020;10(1):2506. https://doi.org/10.1038/s41598-020-59105-0. PMID: 32054896; PMCID: PMC7018952.CrossRefPubMedPubMedCentral

57.

Papa EV, Dong X, Hassan M. Resistance training for activity limitations in older adults with skeletal muscle function deficits: A systematic review. Clin Interv Aging. 2017;12:955–61. https://doi.org/10.2147/CIA.S104674. PMID: 28670114; PMCID: PMC5479297.CrossRefPubMedPubMedCentral

58.

Ludyga S, Gerber M, Pühse U, Looser VN, Kamijo K. Systematic review and meta-analysis investigating moderators of long-term effects of exercise on cognition in healthy individuals. Nat Hum Behav. 2020;4(6):603–12. https://doi.org/10.1038/s41562-020-0851-8.CrossRefPubMed

59.

Sansano-Nadal O, Giné-Garriga M, Brach JS, Wert DM, Jerez-Roig J, Guerra-Balic M, Oviedo G, Fortuño J, Gómara-Toldrà N, Soto-Bagaria L, Pérez LM. Exercise-based interventions to enhance long-term sustainability of physical activity in older adults: A systematic review and meta-analysis of randomized clinical trials. Int J Environ Res Public Health. 2019;16(14):2527. https://doi.org/10.3390/ijerph16142527.CrossRefPubMedPubMedCentral

60.

Barha CK, Falck RS, Skou ST, Liu-Ambrose T. Personalising exercise recommendations for healthy cognition and mobility in ageing: Time to consider one’s pre-existing function and genotype (Part 2). Br J Sports Med. 2020. https://doi.org/10.1136/bjsports-2016-096710.CrossRefPubMed

61.

Huang H, Li W, Qin Z, Shen H, Li X, Wang W. Physical exercise increases peripheral brain-derived neurotrophic factors in patients with cognitive impairment: A meta-analysis. Restor Neurol Neurosci. 2021;39(3):159–71. https://doi.org/10.3233/RNN-201060.CrossRefPubMed

62.

Jia RX, Liang JH, Xu Y, Wang YQ. Effects of physical activity and exercise on the cognitive function of patients with Alzheimer disease: A meta-analysis. BMC Geriatr. 2019;19:1–4. https://doi.org/10.1186/s12877-019-1175-2.CrossRef

63.

Lopez-Ortiz S, Valenzuela PL, Seisdedos MM, Morales JS, Vega T, Castillo-Garcia A, Nisticò R, Mercuri NB, Lista S, Lucia A, Santos-Lozano A. Exercise interventions in Alzheimer’s disease: A systematic review and meta-analysis of randomized controlled trials. Ageing Res Rev. 2021;72:101479. https://doi.org/10.1016/j.arr.2021.101479.CrossRefPubMed

64.

Stigger FS, Zago Marcolino MA, Portela KM, Plentz RD. Effects of exercise on inflammatory, oxidative, and neurotrophic biomarkers on cognitively impaired individuals diagnosed with dementia or mild cognitive impairment: A systematic review and meta-analysis. J Gerontol A Biol Sci Med Sci. 2019;74(5):616–24. https://doi.org/10.1093/gerona/gly173.CrossRefPubMed

65.

Silva TB, Bratkauskas JS, Barbosa ME, Silva GA, Zumkeller MG, Moraes LC, Lessa PP, Cardoso NP, Ordonez TN, Brucki SM. Long-term studies in cognitive training for older adults a systematic review. Dement Neuropsychol. 2022;16:135–52. https://www.scielo.br/j/dn/a/NNWzLbRkxTJVQn8wsSh56cg/.CrossRefPubMedPubMedCentral

66.

Duda BM, Sweet LH. Functional brain changes associated with cognitive training in healthy older adults: A preliminary ALE meta-analysis. Brain Imaging Behav. 2020;14(4):1247–62. https://link.springer.com/article/10.1007/s11682-019-00080-0.CrossRefPubMed

67.

Ten Brinke LF, Davis JC, Barha CK, Liu-Ambrose T. Effects of computerized cognitive training on neuroimaging outcomes in older adults: A systematic review. BMC Geriatr. 2017;17(1):1–20. https://doi.org/10.1186/s12877-017-0529-x.CrossRef

68.

Butler M, McCreedy E, Nelson VA, Desai P, Ratner E, Fink HA, Hemmy LS, McCarten JR, Barclay TR, Brasure M, Davila H. Does cognitive training prevent cognitive decline? A systematic review. Ann Intern Med. 2018;168(1):63–8. https://www.acpjournals.org/doi/full/10.7326/M17-1531.CrossRefPubMed

69.

Willis SL, Tennstedt SL, Marsiske M, Ball K, Elias J, Koepke KM, Morris JN, Rebok GW, Unverzagt FW, Stoddard AM, Wright E. Long-term effects of cognitive training on everyday functional outcomes in older adults. JAMA. 2006;296(23):2805–14. https://doi.org/10.1001/jama.296.23.2805.CrossRefPubMedPubMedCentral

70.

Ross LA, Edwards JD, O’Connor ML, Ball KK, Wadley VG, Vance DE. The transfer of cognitive speed of processing training to older adults’ driving mobility across 5 years. J Gerontol B Psychol Sci Soc Sci. 2016;71(1):87–97. https://doi.org/10.1093/geronb/gbv022.CrossRefPubMed

71.

Hafdi M, Hoevenaar-Blom M, Richard E. Multi-domain interventions for the prevention of dementia and cognitive decline. Cochrane Database Syst Rev. 2021;11(11):CD013572. https://doi.org/10.1002/14651858.CD013572.pub2.CrossRefPubMed

72.

Rosenberg A, Ngandu T, Rusanen M, Antikainen R, Bäckman L, Havulinna S, Hänninen T, Laatikainen T, Lehtisalo J, Levälahti E, Lindström J, Paajanen T, Peltonen M, Soininen H, Stigsdotter-Neely A, Strandberg T, Tuomilehto J, Solomon A, Kivipelto M. Multidomain lifestyle intervention benefits a large elderly population at risk for cognitive decline and dementia regardless of baseline characteristics: The FINGER trial. Alzheimers Dement. 2018;14(3):263–70. https://doi.org/10.1016/j.jalz.2017.09.006.CrossRefPubMed

73.

Kivipelto M, Mangialasche F, Snyder HM, Allegri R, Andrieu S, Arai H, Baker L, Belleville S, Brodaty H, Brucki SM, Calandri I. World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia. Alzheimers Dement. 2020;16(7):1078–94. https://doi.org/10.1002/alz.12123.CrossRefPubMed

74.

Coley N, Ngandu T, Lehtisalo J, Soininen H, Vellas B, Richard E, Kivipelto M, Andrieu S, van Gool P, van Charante EM, Beishuizen C. Adherence to multidomain interventions for dementia prevention: Data from the FINGER and MAPT trials. Alzheimer’s Dement. 2019;15(6):729–41. https://doi.org/10.1016/j.jalz.2019.03.005.CrossRef

75.

Ngandu T, Lehtisalo J, Korkki S, Solomon A, Coley N, Antikainen R, Bäckman L, Hänninen T, Lindström J, Laatikainen T, Paajanen T. The effect of adherence on cognition in a multidomain lifestyle intervention (FINGER). Alzheimers Dement. 2022;18(7):1325–34. https://doi.org/10.1002/alz.12492.CrossRefPubMed

76.

Rosenstock IM. Health Belief Model. In: Kazdin AE, editor. Encyclopedia of psychology, vol. 4. Oxford University Press; 2000. p. 78–80.

77.

Ravi K, Indrapriyadharshini K, Madankumar PD. Application of health behavioral models in smoking cessation–a systematic review. Indian J Public Health. 2021;65(2):103–9. https://journals.lww.com/IJPH/Fulltext/2021/65020/Application_of_Health_Behavioral_Models_in_Smoking.3.aspx.CrossRefPubMed

78.

Jeon HO, Chae M, Kim A. Effects of medication adherence interventions for older adults with chronic illnesses: A systematic review and meta-analysis. Osong Public Health Res Perspect. 2022;13(5):328–40. https://doi.org/10.24171/j.phrp.2022.0168.CrossRefPubMedPubMedCentral

79.

Ritchie D, Van den Broucke S, Van Hal G. The health belief model and theory of planned behavior applied to mammography screening: A systematic review and meta-analysis. Public Health Nurs. 2021;38(3):482–92. https://onlinelibrary.wiley.com/doi/abs/10.1111/phn.12842.CrossRefPubMed

80.

Deslippe AL, Soanes A, Bouchaud CC, Beckenstein H, Slim M, Plourde H, Cohen TR. Barriers and facilitators to diet, physical activity and lifestyle behavior intervention adherence: A qualitative systematic review of the literature. Int J Behav Nutr Phys Act. 2023;20(1):1–25. https://ijbnpa.biomedcentral.com/articles/10.1186/s12966-023-01424-2.CrossRef

81.

Li H, Zhang J, Wang L, Yang T, Yang Y. A health promoting-lifestyle prediction model for dementia prevention among chinese adults: based on the health belief model. BMC Public Health. 2022;22(1):2450. https://doi.org/10.1186/s12889-022-14828-9.CrossRefPubMedPubMedCentral

82.

Lee J, Lim JM. Factors associated with the experience of cognitive training apps for the prevention of dementia: cross-sectional study using an extended health belief model. J Med Internet Res. 2022;24(1):e31664.CrossRefPubMedPubMedCentral

83.

Smith BJ, Ali S, Quach H. The motivation and actions of Australians concerning brain health and dementia risk reduction. Health Promot J Austr. 2015;26(2):115–21. https://doi.org/10.1071/HE14111.CrossRefPubMed

84.

Seifan A, Ganzer CA, Vermeylen F, Parry S, Zhu J, Lyons A, Isaacson R, Kim S. Development and validation of the Alzheimer’s prevention beliefs measure in a multi-ethnic cohort—a behavioral theory approach. J Public Health. 2017;39(4):863–73. https://academic.oup.com/jpubhealth/article/39/4/863/2874261.

85.

Vrijsen J, Matulessij TF, Joxhorst T, et al. Knowledge, health beliefs and attitudes towards dementia and dementia risk reduction among the Dutch general population: A cross-sectional study. BMC Public Health. 2021;21:857. https://doi.org/10.1186/s12889-021-10913-7.CrossRefPubMedPubMedCentral

86.

Siette J, Dodds L, Deckers K, Köhler S, Armitage CJ. Cross-sectional survey of attitudes and beliefs towards dementia risk reduction among Australian older adults. BMC Public Health. 2023;23(1):1–3. https://doi.org/10.1186/s12889-023-15843-0.CrossRef

Title: Health Behavior Change to Mitigate Dementia Risk: An Updated Review
Authors: Victoria Sanborn
Jennifer D. Davis
Laura E. Korthauer
Publication date: 19-07-2024
Publisher: Springer US
Keywords: Dementia
Dementia
Alzheimer's Disease
Alzheimer Disease
Published in: Current Geriatrics Reports / Issue 3/2024
Electronic ISSN: 2196-7865
DOI: https://doi.org/10.1007/s13670-024-00421-y

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