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Annals of Surgical Oncology
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05-01-2023 | Cytostatic Therapy | Aso Author Reflections

ASO Author Reflections: Neoadjuvant Oxaliplatin Therapy for Peritoneal Carcinomatosis, Any Impact on Subsequent Hyperthermic Intraperitoneal Chemotherapy Perfusion?

Authors: Christopher W. Mangieri, MD, Edward A. Levine, MD

Published in: Annals of Surgical Oncology | Issue 4/2023

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Excerpt

Management of peritoneal carcinomatosis continues to evolve from previous therapy limited to palliative interventions to current advanced therapy with curative intent. Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) likewise has progressed from experimental therapy to a well-accepted standard oncologic procedure. CRS-HIPEC continues to be more frequently utilized worldwide, particularly for the management of carcinomatosis secondary to colorectal and appendiceal cancers. The treatment algorithm for many advanced gastrointestinal cancers includes neoadjuvant chemotherapy (NAT). The Chicago Consensus Working Group recommends NAT prior to CRS-HIPEC for appendiceal and colorectal adenocarcinomas.1,2 The effect of NAT on subsequent HIPEC is greatly unknown and has not been previously studied. …
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Metadata
Title
ASO Author Reflections: Neoadjuvant Oxaliplatin Therapy for Peritoneal Carcinomatosis, Any Impact on Subsequent Hyperthermic Intraperitoneal Chemotherapy Perfusion?
Authors
Christopher W. Mangieri, MD
Edward A. Levine, MD
Publication date
05-01-2023
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 4/2023
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-022-13009-7

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