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Open Access 03-02-2025 | Cytostatic Therapy | ASO Author Reflections

ASO Author Reflections: Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) of Extraperitoneal Abdominal Disease, a Likely Common Practice but Infrequently Reported

Authors: Christopher W. Mangieri, MD, Edward A. Levine, MD

Published in: Annals of Surgical Oncology

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Excerpt

The genesis of peritoneal surface malignancy (PSM) surgery dates back to the late 1920s with Dr. Meig’s pioneering work evaluating cytoreductive surgery (CRS) with ovarian cancer. Advances in CRS were achieved by surgeons such as Dr. Griffith at the National Cancer Institute and Dr. Long at the University of Alabama expanding the scope of CRS. Dr. Sugarbaker is primarily accredited for combining hyperthermic intraperitoneal chemotherapy (HIPEC) with CRS into the modern practice of PSM surgery. Randomized control trials led by Dr. Verwaal and Dr. Cashin as well as the most recent PRODIGE7 trial have validated CRS-HIPEC as standard-of-care therapy for PSM. This foundational research and these landmarks trials are rooted in the premise that CRS-HIPEC is effective only when disease is limited to the peritoneal cavity. …
Literature
1.
go back to reference Dubé P, et al. Guidelines on the use of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients with peritoneal surface malignancy arising from colorectal or appendiceal neoplasms. Curr Oncol. 2015;22(2):100–12.CrossRef Dubé P, et al. Guidelines on the use of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients with peritoneal surface malignancy arising from colorectal or appendiceal neoplasms. Curr Oncol. 2015;22(2):100–12.CrossRef
2.
go back to reference Chicago Consensus Working Group, et al. The Chicago consensus on peritoneal surface malignancies: management of appendiceal neoplasms. Cancer. 2020;126(11):2525–33.CrossRef Chicago Consensus Working Group, et al. The Chicago consensus on peritoneal surface malignancies: management of appendiceal neoplasms. Cancer. 2020;126(11):2525–33.CrossRef
3.
go back to reference Chicago Consensus Working Group, et al. The Chicago consensus on peritoneal surface malignancies: management of colorectal metastases. Cancer. 2020;126(11):2534–40.CrossRef Chicago Consensus Working Group, et al. The Chicago consensus on peritoneal surface malignancies: management of colorectal metastases. Cancer. 2020;126(11):2534–40.CrossRef
5.
go back to reference Beal, Eliza W., et al. "Is cytoreductive surgery-hyperthermic intraperitoneal chemotherapy still indicated in patients with extraperitoneal disease?." J Surg Res 277 (2022): 269-278. Beal, Eliza W., et al. "Is cytoreductive surgery-hyperthermic intraperitoneal chemotherapy still indicated in patients with extraperitoneal disease?." J Surg Res 277 (2022): 269-278.
Metadata
Title
ASO Author Reflections: Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) of Extraperitoneal Abdominal Disease, a Likely Common Practice but Infrequently Reported
Authors
Christopher W. Mangieri, MD
Edward A. Levine, MD
Publication date
03-02-2025
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-025-16968-9
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