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Current Cardiology Reports

Assessing Regurgitation Severity, Adverse Remodeling, and Fibrosis with CMR in Primary Mitral Regurgitation

  • 15-05-2024
  • CSF Drainage
  • Cardiac PET, CT, and MRI (P Cremer, Section Editor)
Published in:
Authors
Amr Darwish
Akila Bersali
Mujtaba Saeed
Aneesh Dhore
Dimitrios Maragiannis
K. Carlos El-Tallawi
Dipan J. Shah
Published in
Current Cardiology Reports | Issue 7/2024

Abstract

Purpose of Review

This review offers an evidence-based analysis of established and emerging cardiovascular magnetic resonance (CMR) techniques used to assess the severity of primary mitral regurgitation (MR), identify adverse cardiac remodeling and its prognostic effect. The aim is to provide different insights regarding clinical decision-making and enhance the clinical outcomes of patients with MR.

Recent Findings

Cardiac remodeling and myocardial replacement fibrosis are observed frequently in the presence of substantial LV volume overload, particularly in cases with severe primary MR. CMR serves as a useful diagnostic imaging modality in assessing mitral regurgitation severity, early detection of cardiac remodeling, myocardial dysfunction, and myocardial fibrosis, enabling timely intervention before irreversible damage ensues.

Summary

Incorporating myocardial remodeling in terms of left ventricular (LV) dilatation and myocardial fibrosis with quantitative MR severity assessment by CMR may assist in defining optimal timing of intervention.
Title
Assessing Regurgitation Severity, Adverse Remodeling, and Fibrosis with CMR in Primary Mitral Regurgitation
Authors
Amr Darwish
Akila Bersali
Mujtaba Saeed
Aneesh Dhore
Dimitrios Maragiannis
K. Carlos El-Tallawi
Dipan J. Shah
Publication date
15-05-2024
Publisher
Springer US
Keyword
CSF Drainage
Published in
Current Cardiology Reports / Issue 7/2024
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-024-02069-8
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This content is intended for healthcare professionals outside of the UK.

Independent Medical Education Grant:
  • Bayer HealthCare Pharmaceuticals Inc.
Learn more Link opens in a new window
Image Credits
Abstract graphic of layered, concentric circular shapes in bright green, pink, blue, and purple on a dark blue background. The rings and segments form a complex radial pattern without text/© Springer Health+ IME