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Published in: Infection 4/2022

Open Access 22-12-2021 | COVID-19 | Correspondence

Dexamethasone enhances risk of herpes zoster in severe COVID-19 infection

Authors: Nathan B. Price, Charles Grose

Published in: Infection | Issue 4/2022

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Excerpt

We read the review article about herpes zoster and COVID-19 infection with great interest [1]. As an example from the review, the author noted that the Brazilian Ministry of Health had documented an increase in cases of herpes zoster from 9.69 to 14.13 cases per million people in the Rio de Janeiro region pre-and post-COVID-19 epidemic. We propose that we can answer the question whether this association is a coincidence or a causal relationship, at least in several of the severe treated cases. There is a 70-year history in the medical literature about the induction of herpes zoster in a wide variety of patients who were prescribed corticosteroid therapy. We have recently reviewed this association [2]. This association has been documented in both immunocompetent and immunodeficient children and both immunocompetent and immunodeficient adults [3]. …
Literature
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go back to reference Price NB, Grose C. Corticosteroids contribute to serious adverse events following live attenuated varicella vaccination and live attenuated zoster vaccination. Vaccines (Basel). 2021;9:23.CrossRef Price NB, Grose C. Corticosteroids contribute to serious adverse events following live attenuated varicella vaccination and live attenuated zoster vaccination. Vaccines (Basel). 2021;9:23.CrossRef
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go back to reference Marra F, Lo E, Kalashnikov V, Richardson K. Risk of herpes zoster in individuals on biologics, disease-modifying antirheumatic drugs, and/or corticosteroids for autoimmune diseases: a systematic review and meta-analysis. Open Forum Infect Dis. 2016;3: ofw05.CrossRef Marra F, Lo E, Kalashnikov V, Richardson K. Risk of herpes zoster in individuals on biologics, disease-modifying antirheumatic drugs, and/or corticosteroids for autoimmune diseases: a systematic review and meta-analysis. Open Forum Infect Dis. 2016;3: ofw05.CrossRef
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go back to reference Hasan SS, Capstick T, Ahmed R, Kow CS, Mazhar F, Merchant HA, Zaidi STR. Mortality in COVID-19 patients with acute respiratory distress syndrome and corticosteroids use: a systematic review and meta-analysis. Expert Rev Respir Med. 2020;14:1149–63.CrossRef Hasan SS, Capstick T, Ahmed R, Kow CS, Mazhar F, Merchant HA, Zaidi STR. Mortality in COVID-19 patients with acute respiratory distress syndrome and corticosteroids use: a systematic review and meta-analysis. Expert Rev Respir Med. 2020;14:1149–63.CrossRef
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go back to reference Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, Staplin N, Brightling C, Ustianowski A, Elmahi E, Prudon B, Green C, Felton T, Chadwick D, Rege K, Fegan C, Chappell LC, Faust SN, Jaki T, Jeffery K, Montgomery A, Rowan K, Juszczak E, Baillie JK, Haynes R, Landray MJ. Dexamethasone in hospitalized patients with Covid-19. N Engl J Med. 2021;384:693–704.CrossRef Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, Staplin N, Brightling C, Ustianowski A, Elmahi E, Prudon B, Green C, Felton T, Chadwick D, Rege K, Fegan C, Chappell LC, Faust SN, Jaki T, Jeffery K, Montgomery A, Rowan K, Juszczak E, Baillie JK, Haynes R, Landray MJ. Dexamethasone in hospitalized patients with Covid-19. N Engl J Med. 2021;384:693–704.CrossRef
Metadata
Title
Dexamethasone enhances risk of herpes zoster in severe COVID-19 infection
Authors
Nathan B. Price
Charles Grose
Publication date
22-12-2021
Publisher
Springer Berlin Heidelberg
Published in
Infection / Issue 4/2022
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-021-01747-x

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