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COVID-19

Vitamin D in gut homeostasis, infection, and immune regulation

This international consensus statement integrates epidemiological, mechanistic, and interventional research findings, emphasizing the clinical relevance of maintaining adequate vitamin D status across a range of systems.

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Editor's Choice

Advancing vaccination strategies for older adults

Insights from the 2025 Adult Immunization Board Meeting discussing optimizing vaccination strategies in European adults aged 65-years and over. Shifting from fragmented efforts to cohesive, system-wide approaches is key, but what are the challenges that need to be overcome?

Long COVID biomarkers in children and young adults

The diagnosis of long COVID is challenging due to the heterogeneity of cases, particularly in young patients. What are the biomarkers that warrant further investigation for their diagnostic potential?

Community-acquired respiratory infections in cancer patients

Updated guideline from the German Society for Hematology and Medical Oncology on the prevention, diagnosis, and management of community-acquired respiratory virus infections in people with cancer.

A silver lining of COVID-19?

This patient with pulmonary alveolar proteinosis experienced significant remission after contracting COVID-19, raising the possibility of an immunomodulatory effect.

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Case Studies

A silver lining of COVID-19?

This patient with pulmonary alveolar proteinosis experienced significant remission after contracting COVID-19, raising the possibility of an immunomodulatory effect.

COVID-19-associated large-vessel vasculitis

Three cases of new-onset LVV that developed after COVID-19. All patients had elevated anti-ACE2 antibodies that normalized after clinical remission. Do these antibodies have a role in the pathogenesis of post-COVID-19 vasculitis?

Thromboembolic complications in COVID-19, TB coninfection

This case highlights the rare occurrence of a right atrial thrombus and PE in a patient with COVID-19, possibly exacerbated by TB coinfection. Thromboembolectomy, anticoagulation and an antimicrobial regimen were key to successful treatment.

Current Reviews

The Economic Value of Non-pharmaceutical Interventions for Influenza and COVID-19: A Systematic Review

Non-pharmaceutical interventions (NPIs) include a broad set of measures designed to reduce transmission in the absence of, or alongside, pharmaceutical options such as vaccines and antivirals, and include personal protective, environmental, social …

Unveiling the genitourinary phenotype of long COVID: a systematic review and meta-analysis

Long COVID is defined by the World Health Organization (WHO) as the persistence of symptoms beyond 12 weeks after acute SARS-CoV-2 infection, in the absence of an alternative explanatory diagnosis. Its global prevalence has been estimated at …

Post-MIS-C cardiovascular outcomes: a systematic review

Limited knowledge and variability in findings exist regarding the resolution of cardiovascular outcomes following Multisystem Inflammatory Syndrome in Children (MIS-C). We conducted a systematic review to estimate the frequency of cardiovascular …

Further Reading

Public preferences for saving lives versus life-years: evidence from a person-trade-off experiment in 12 countries during the COVID-19 pandemic

Health technology assessment (HTA) often prioritises outcomes measured in life-years or Quality-Adjusted Life Years (QALYs), implying a focus on maximising (quality-adjusted) life-years rather than saving lives. This study investigates public …

Transcutaneous Auricular Vagal Nerve Stimulation Against Fatigue Syndrome in Patients with Long COVID: Results of the Randomized, Placebo-Controlled Clinical Pilot Trial COVIVA

  • Open Access
  • Fatigue
  • Original Research

Fatigue is a the most prominent symptom in patients with long COVID, with a prevalence of around 6–7% [ 1 ]. The causes of long COVID are still not fully understood, although autoimmune processes, thrombosis, and mitochondrial dysfunction are being …

The impact of testing positive versus negative for COVID-19 on health-related quality of life: cross-sectional evidence from the Alberta post-COVID-19 follow-up survey

The novel Coronavirus Disease 2019 (COVID-19) has both short- and long-term physical and psychological outcomes that may persist after acute infection. Since the start of the COVID-19 pandemic, a substantial body of literature has shown that many …

Comparison of [18F]DPA-814 with [18F]DPA-714 for TSPO Imaging in an Experimental Model

Molecular imaging allows for minimal-invasive visualization of biological processes at both the cellular and molecular level, offering insights beyond traditional anatomical imaging. Among its various applications, inflammation imaging has gained …

Image Credits
Solidarity/consensus concept image/© Andriy Onufriyenko / moment / Getty Images, Elderly patient vaccination/© Luis Alvarez / DigitalVision / Getty (symbolic image with models), Doctor with child/© FatCamera / E+ / Getty (symbolic image with models), File folder with guidelines tab/© tang90246 / stock.adobe.com, Lung biopsy specimen of patient with pulmonary alveolar proteinosis/© 2025, Chunyu Xu et al, BMC Pulm Med, Boy with a doctor at a medical appointment/© Wavebreakmedia / Getty Images / iStock (symbolic image with models), Close-up of older woman receiving oxygen/© boonstudio / Getty Images / iStock (symbolic image with model), Mother measuring daughter's glucose with digital device/© La Lumiere / Getty Images / iStock (symbolic image with models), Negative COVID-19 antigen test/© Michele Ursi / stock.adobe.com, PET-CT scan of patient with COVID-19-associated large-vessel vasculitis/© 2025, Setsuko Oyama et al, under exclusive licence to International League of Associations for Rheumatology (ILAR), Clin Rheumatol, Surgical specimen of removed embolism/© 2025, Maryam Nasiri et al. Thrombosis J