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Interstitial pneumonia caused by drug-eluting stent

A patient with a rapamycin-eluting stent developed eosinophilia and interstitial pneumonia, highlighting the need for awareness of possible side effects of stent implantation so treatment can be started promptly.

Editor's Choice

Pulmonary cryptococcosis in an immunocompetent child

Open Access Cryptococcosis Case Study

A rare case of the opportunistic fungal infection cryptococcosis in an immunocompetent child who presented with pulmonary cavities. Next-generation sequencing identified the pathogen, which was treated successfully with fluconazole.

IPF patients report cough relief with morphine

PACIFY-COUGH results support the use of low-dose, controlled-release morphine to ease cough symptoms in patients with idiopathic pulmonary fibrosis.

Chronic cough as a genetic neurological disorder? Insights from CANVAS

Open Access Cough Review

Current thinking on the mechanisms underlying chronic cough, and how this might fit with the existence of cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS), a genetically driven disorder that has cough as a frequent feature.

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Case Studies

Interstitial pneumonia caused by drug-eluting stent

A patient with a rapamycin-eluting stent developed eosinophilia and interstitial pneumonia, highlighting the need for awareness of possible side effects of stent implantation so treatment can be started promptly.

Pulmonary cryptococcosis in an immunocompetent child

Open Access Cryptococcosis Case Study

A rare case of the opportunistic fungal infection cryptococcosis in an immunocompetent child who presented with pulmonary cavities. Next-generation sequencing identified the pathogen, which was treated successfully with fluconazole.

Plastic bronchitis associated with respiratory syncytial virus infection

Open Access Childhood Bronchitis Case Study

RSV has rarely been reported as an etiological agent for plastic bronchitis, but should be considered if hypoxemia is unresponsive to mechanical ventilation and ECMO.

Current Reviews

Managing Symptoms of Systemic Sclerosis for the Allergist-Immunologist

Scleroderma is an umbrella term. The origin of the word arises from Greek with ‘sclero’—thickening, ‘derma’—skin, referring to the hallmark symptom of thick skin. Within scleroderma, there are two major categories: systemic sclerosis and localized …

Drugs Targeting Cough Receptors: New Therapeutic Options in Refractory or Unexplained Chronic Cough

Cough Leading Article

Refractory chronic cough is a disabling disease with very limited therapeutic options. A better understanding of cough pathophysiology has led to the development of emerging drugs targeting cough receptors. Recent strides have illuminated novel …

Predictive Factors for Successful Decannulation in Patients with Tracheostomies and Brain Injuries: A Systematic Review

Open Access Tracheostomy Review

Neurological patients frequently have disorders of consciousness, swallowing disorders, or neurological states that are incompatible with extubation. Therefore, they frequently require tracheostomies during their stay in an intensive care unit.

Chronic cough: more than just a persistent cough: a systematic literature review to understand the impact of chronic cough on quality of life

Cough Review

Cough is an essential reflex mechanism to prevent aspiration and enhance airway clearance [ 1 , 2 ]. However, excessive and prolonged cough may occur when the defense mechanism function of cough has been impaired [ 1 ]. In such cases, cough can be …

Further Reading

The Effect of Long-Term Azithromycin on Objective and Subjective Cough in Chronic Respiratory Disease: A Systematic Review and Meta-analysis of Randomised Controlled Trials and Noncomparative Studies

Open Access Cough RESEARCH

Chronic respiratory diseases affect one in five people in the United Kingdom and now represent the third leading cause of death in England [ 1 ]. Amongst such patients, the symptom of cough is extremely prevalent and often accounts for a …

Patient Perception of Cough in Interstitial Lung Disease; Impact of Cough Hypersensitivity

Open Access Cough BRIEF REPORT

Chronic cough (CC, lasting > 8 weeks) is a condition affecting approximately 10% of the global population and is associated with significant impact on quality of life [ 1 ]. Cough hypersensitivity is hypothesised as a key mechanistic driver of CC …

Tolerability of Antihypertensive Medications: The Influence of Age

Open Access Cough Original article

Hypertension represents one of the leading modifiable risk factors for cardiovascular morbidity and mortality, affecting more than 1.28 billion adults worldwide with increasing prevalence in advancing age [ 1 ]. Recent literature has provided clear …