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17-03-2023 | Computed Tomography | Original Article–Urology

The efficacy of ultrasonography for the detection of upper tract urothelial carcinoma

Authors: Shigeki Koterazawa, Shinya Somiya, Katsuhiro Ito, Takao Haitani, Yuki Makino, Ryuichiro Arakaki, Norio Kawase, Yoshihito Higashi, Hitoshi Yamada, Toru Kanno

Published in: Journal of Medical Ultrasonics | Issue 2/2023

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Abstract

Purpose

Ultrasonography and computed tomography urography are two commonly used modalities to image the upper tracts for the evaluation of hematuria. This study evaluated the efficacy of ultrasonography for the detection of upper tract urothelial carcinoma compared to computed tomography urography as a standard reference.

Methods

This retrospective study included patients with urothelial carcinoma of the renal pelvis and/or ureter who were diagnosed using computed tomography urography and underwent surgical treatment. We calculated the sensitivity of ultrasonography in upper tract urothelial carcinoma diagnosis, further classified the degree of hydronephrosis on ultrasonography, and analyzed the relationship between the sensitivity and the degree of hydronephrosis and tumor location. Additionally, the usefulness of the combination of the screening ultrasonography findings, the presence of gross hematuria, and/or urine cytology was analyzed.

Results

This study included 136 patients with upper urothelial carcinoma. Ultrasonography in the diagnosis had 45.6% sensitivity, and ultrasonography findings, including the detection of hydronephrosis, were present in 72.8%. The presence of hydronephrosis and tumor location were associated with detection by ultrasonography. The tumor was identified in a total of 134 (98.5%) patients by combining tumor detection and hydronephrosis using ultrasonography with gross hematuria and positive urine cytology as screening.

Conclusion

Ultrasonography showed acceptable sensitivity for upper tract urothelial carcinoma diagnosis. Considering the hydronephrosis findings, ultrasonography is a useful screening tool for upper tract urothelial carcinoma. Additionally, excessive computed tomography examinations can be reduced by adding gross hematuria and positive urine cytology.
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Metadata
Title
The efficacy of ultrasonography for the detection of upper tract urothelial carcinoma
Authors
Shigeki Koterazawa
Shinya Somiya
Katsuhiro Ito
Takao Haitani
Yuki Makino
Ryuichiro Arakaki
Norio Kawase
Yoshihito Higashi
Hitoshi Yamada
Toru Kanno
Publication date
17-03-2023
Publisher
Springer Nature Singapore
Published in
Journal of Medical Ultrasonics / Issue 2/2023
Print ISSN: 1346-4523
Electronic ISSN: 1613-2254
DOI
https://doi.org/10.1007/s10396-023-01299-7

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