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Pediatric Radiology
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Open Access 08-06-2024 | Computed Tomography | Review

Connective tissue disease-associated lung disease in children

Authors: Andrew H. Schapiro, Cara E. Morin, Kathryn A. Wikenheiser-Brokamp, Aki A. Tanimoto

Published in: Pediatric Radiology | Issue 7/2024

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Abstract

Connective tissue diseases are a heterogeneous group of autoimmune diseases that can affect a variety of organ systems. Lung parenchymal involvement is an important contributor to morbidity and mortality in children with connective tissue disease. Connective tissue disease-associated lung disease in children often manifests as one of several radiologic-pathologic patterns of disease, with certain patterns having a propensity to occur in association with certain connective tissue diseases. In this article, key clinical, histopathologic, and computed tomography (CT) features of typical patterns of connective tissue disease-associated lung disease in children are reviewed, with an emphasis on radiologic-pathologic correlation, to improve recognition of these patterns of lung disease at CT and to empower the pediatric radiologist to more fully contribute to the care of pediatric patients with these conditions.

Graphical abstract

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Metadata
Title
Connective tissue disease-associated lung disease in children
Authors
Andrew H. Schapiro
Cara E. Morin
Kathryn A. Wikenheiser-Brokamp
Aki A. Tanimoto
Publication date
08-06-2024

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