Skip to main content
Top
Published in:

01-11-2024 | Research

Complication rates of guided bone regeneration using titanium-reinforced PTFE membranes: a retrospective analysis

Authors: Alexander-N. Zeller, Rainer Schenk, Martin Bonsmann, Gereon Stockbrink, Sebastian Becher, Andreas Pabst

Published in: Clinical Oral Investigations | Issue 11/2024

Login to get access

Abstract

Introduction

This study analyzed complication rates of guided bone regeneration (GBR) using titanium-reinforced polytetrafluoroethylene (PTFE) membranes for alveolar ridge augmentation.

Material and methods

84 patients treated with GBR using titanium-reinforced PTFE membranes (91 sites) were retrospectively analyzed. Complications such as membrane exposure and early removal were analyzed concerning patient age, defect site position, size, simultaneous vs. two-stage implant placement, smoking, and the use of bone grafts (BG) and substitutes (BS).

Results

Early removal due to membrane exposure was necessary in 14/91 sites (15.4%). No correlation was found between early removal and patient age (p = 0.917). Analyzing early removal between the upper and lower jaw and between both jaws’ anterior and posterior tooth regions revealed no correlations (p = 0.381 and 0.477, respectively). Defect sites sizes of 5–6 mm exhibited the highest rate of membrane exposure, requiring early removal, accounting for 57.1% of these sites (8/14). No correlation was observed between the defect sites size and early removal (p = 0.660). Comparison of simultaneous (74 sites) vs. two-stage implant placement (16 sites) showed no correlation with early removal (p = 0.706). Membrane exposure incidence was 42.9% among smokers (27 patients, 32.1%) and 57.1% among non-smokers (57 patients, 67.9%), without correlation. No correlation was found between the type of BG and BS and early removal (p = 0.500).

Conclusion

GBR using titanium-reinforced PTFE membranes is effective for alveolar ridge augmentation and has favorable long-term outcomes.

Clinical relevance

Careful surgical technique and postoperative care can minimize the notable risk of PTFE membrane exposure.
Literature
10.
go back to reference Rothamel D, Schwarz F, Fienitz T, Smeets R, Dreiseidler T, Ritter L, Happe A, Zöller J (2012) Biocompatibility and biodegradation of a native porcine pericardium membrane: results of in vitro and in vivo examinations. Int J Oral Maxillofac Implants 27(1):146–154PubMed Rothamel D, Schwarz F, Fienitz T, Smeets R, Dreiseidler T, Ritter L, Happe A, Zöller J (2012) Biocompatibility and biodegradation of a native porcine pericardium membrane: results of in vitro and in vivo examinations. Int J Oral Maxillofac Implants 27(1):146–154PubMed
13.
14.
go back to reference Solomon S-M, Sufaru I-G, Teslaru S, Ghiciuc CM, Stafie CS (2022) Finding the Perfect Membrane: Current Knowledge on Barrier Membranes in Regenerative Procedures: A Descriptive Review. Appl Sci 12(3):1042CrossRef Solomon S-M, Sufaru I-G, Teslaru S, Ghiciuc CM, Stafie CS (2022) Finding the Perfect Membrane: Current Knowledge on Barrier Membranes in Regenerative Procedures: A Descriptive Review. Appl Sci 12(3):1042CrossRef
18.
go back to reference Sbricoli L, Guazzo R, Annunziata M, Gobbato L, Bressan E, Nastri L (2020) Selection of Collagen Membranes for Bone Regeneration: A Literature Review. Materials 13(3):786CrossRefPubMedPubMedCentral Sbricoli L, Guazzo R, Annunziata M, Gobbato L, Bressan E, Nastri L (2020) Selection of Collagen Membranes for Bone Regeneration: A Literature Review. Materials 13(3):786CrossRefPubMedPubMedCentral
19.
go back to reference Kloss FR, Kämmerer PW, Kloss-Brandstätter A (2023) Risk Factors for Complications Following Staged Alveolar Ridge Augmentation and Dental Implantation: A Retrospective Evaluation of 151 Cases with Allogeneic and 70 Cases with Autogenous Bone Blocks. J Clin Med 12(1). https://doi.org/10.3390/jcm12010006 Kloss FR, Kämmerer PW, Kloss-Brandstätter A (2023) Risk Factors for Complications Following Staged Alveolar Ridge Augmentation and Dental Implantation: A Retrospective Evaluation of 151 Cases with Allogeneic and 70 Cases with Autogenous Bone Blocks. J Clin Med 12(1). https://​doi.​org/​10.​3390/​jcm12010006
22.
go back to reference Urban IA, Jovanovic SA, Lozada JL (2009) Vertical ridge augmentation using guided bone regeneration (GBR) in three clinical scenarios prior to implant placement: a retrospective study of 35 patients 12 to 72 months after loading. Int J Oral Maxillofac Implants 24(3):502–510PubMed Urban IA, Jovanovic SA, Lozada JL (2009) Vertical ridge augmentation using guided bone regeneration (GBR) in three clinical scenarios prior to implant placement: a retrospective study of 35 patients 12 to 72 months after loading. Int J Oral Maxillofac Implants 24(3):502–510PubMed
23.
go back to reference Zitzmann NU, Naef R, Schärer P (1997) Resorbable versus nonresorbable membranes in combination with Bio-Oss for guided bone regeneration. Int J Oral Maxillofac Implants 12(6):844–852PubMed Zitzmann NU, Naef R, Schärer P (1997) Resorbable versus nonresorbable membranes in combination with Bio-Oss for guided bone regeneration. Int J Oral Maxillofac Implants 12(6):844–852PubMed
27.
28.
go back to reference Simion M, Baldoni M, Rossi P, Zaffe D (1994) A comparative study of the effectiveness of e-PTFE membranes with and without early exposure during the healing period. Int J Periodontics Restorative Dent 14(2):166–180PubMed Simion M, Baldoni M, Rossi P, Zaffe D (1994) A comparative study of the effectiveness of e-PTFE membranes with and without early exposure during the healing period. Int J Periodontics Restorative Dent 14(2):166–180PubMed
36.
go back to reference Troeltzsch M, Kauffmann P, Troeltzsch M, Schiegnitz E, Brockmeyer P, Kaemmerer P, Pabst A, Al-Nawas B (2021) Die S2k-LL -Implantologische Indikationen für die Anwendung von Knochenersatzmaterialien (083–009): wissenschaftliche Quintessenzen*, 180–188. https://doi.org/10.3238/dzz.2021.0014 Troeltzsch M, Kauffmann P, Troeltzsch M, Schiegnitz E, Brockmeyer P, Kaemmerer P, Pabst A, Al-Nawas B (2021) Die S2k-LL -Implantologische Indikationen für die Anwendung von Knochenersatzmaterialien (083–009): wissenschaftliche Quintessenzen*, 180–188. https://​doi.​org/​10.​3238/​dzz.​2021.​0014
37.
go back to reference Palkovics D, Rider P, Rogge S, Kačarević Ž P, Windisch P (2023) Possible Applications for a Biodegradable Magnesium Membrane in Alveolar Ridge Augmentation-Retrospective Case Report with Two Years of Follow-Up. Medicina (Kaunas) 59(10). https://doi.org/10.3390/medicina59101698 Palkovics D, Rider P, Rogge S, Kačarević Ž P, Windisch P (2023) Possible Applications for a Biodegradable Magnesium Membrane in Alveolar Ridge Augmentation-Retrospective Case Report with Two Years of Follow-Up. Medicina (Kaunas) 59(10). https://​doi.​org/​10.​3390/​medicina59101698​
Metadata
Title
Complication rates of guided bone regeneration using titanium-reinforced PTFE membranes: a retrospective analysis
Authors
Alexander-N. Zeller
Rainer Schenk
Martin Bonsmann
Gereon Stockbrink
Sebastian Becher
Andreas Pabst
Publication date
01-11-2024
Publisher
Springer Berlin Heidelberg
Published in
Clinical Oral Investigations / Issue 11/2024
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-024-06007-4

Other articles of this Issue 11/2024

Clinical Oral Investigations 11/2024 Go to the issue