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American Journal of Cardiovascular Drugs
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16-12-2024 | Letter to the Editor

Comment on “SGLT2 Inhibitors and How They Work Beyond the Glucosuric Effect”

Authors: Rose Peronard, Stephan Mayntz

Published in: American Journal of Cardiovascular Drugs | Issue 1/2025

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Excerpt

We read with great interest the review by Aristizábal-Colorado et al., which explores the diverse mechanisms underlying the cardioprotective and renoprotective effects of SGLT2 inhibitors [1]. While the review explores metabolic, hemodynamic, and anti-inflammatory effects, we would like to highlight certain gaps and potential oversights that warrant further discussion. …
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Khouri C, Cracowski JL, Roustit M. SGLT-2 inhibitors and the risk of lower-limb amputation: is this a class effect? Diabetes Obes Metab. 2018;20(6):1531–4.CrossRefPubMed
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Li X, Hoogenveen R, El Alili M, Knies S, Wang J, Beulens JWJ, et al. Cost-effectiveness of SGLT2 inhibitors in a real-world population: a MICADO model-based analysis using routine data from a GP registry. Pharmacoeconomics. 2023;41(10):1249–62.CrossRefPubMedPubMedCentral
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Seidu S, Alabraba V, Davies S, Newland-Jones P, Fernando K, Bain SC, et al. SGLT2 Inhibitors—the new standard of care for cardiovascular, renal and metabolic protection in type 2 diabetes: a narrative review. Diabetes Ther. 2024;15(5):1099–124.CrossRefPubMedPubMedCentral
Metadata
Title
Comment on “SGLT2 Inhibitors and How They Work Beyond the Glucosuric Effect”
Authors
Rose Peronard
Stephan Mayntz
Publication date
16-12-2024
Publisher
Springer International Publishing
Published in
American Journal of Cardiovascular Drugs / Issue 1/2025
Print ISSN: 1175-3277
Electronic ISSN: 1179-187X
DOI
https://doi.org/10.1007/s40256-024-00706-9

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