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ESMO 2025: The DYNAMIC-III trial

Prof. Jeanne Tie explains why ctDNA-guided treatment de-escalation could be considered in certain patients with colon cancer despite the trial not meeting its primary endpoint. 

More from ESMO Congress 2025

TIGIT and PD-1 blockade encouraging in gastroesophageal cancer

Novel T-cell therapy shows promise in uveal melanoma

ESMO 2025: The evERA trial

ESMO 2025: The KEYNOTE-905 trial

ESMO 2025: The DYNAMIC-III trial

ctDNA-guided adjuvant atezolizumab improves MIBC survival

POTOMAC supports add-on durvalumab for high-risk NMIBC

Targeted agents show first-line potential in HER2-mutant NSCLC

Adding immunotherapy improves survival in ovarian cancer

PSMAddition shows PFS gain with 177Lu-PSMA-617 in mHSPC

Ivonescimab plus chemo could be new option for squamous NSCLC

Bispecific CAR T-cell therapy promising in R/R DLBCL

Real-world data confirm effectiveness of radium-223

PFS benefit of gedatolisib for advanced breast cancer shown

Tumor-infiltrating clonal hematopoiesis may be a target for cancer treatment

First-line sacituzumab govitecan improves PFS in metastatic TNBC

No success for ctDNA-guided de-escalation in colon cancer

Datopotamab deruxtecan effective in TNBC

Image Credits
Jeanne Tie/© Springer Medicine, Woman receiving an intravenous infusion/© FatCamera / Getty Images / iStock (symbolic image with model), Erica Mayer/© Springer Medicine, Christof Vulsteke/© Springer Medicine, DNA testing of blood - conceptual/© blindturtle / stock.adobe.com