Investigation of the efficiency and stability of a novel visualized lattice CO2 laser–based gynecological therapeutic apparatus for the treatment of cervical diseases in rhesus monkeys

The fractional CO₂ laser is a type of ablative laser. In this study, a novel fractional CO₂ laser therapeutic apparatus was developed for cervical diseases. To compare the depth and diameter of penetration as well as the stability of a novel laser against a control laser emitting at the same wavelength, we tested this using a rhesus monkey model. The cervixes of rhesus monkeys were irradiated with the novel CO₂ laser. The effects of irradiation were assessed by measuring the depths and diameters of the holes created by the laser. In addition, the depths and diameters of the holes were compared between the novel CO₂ laser–based gynecological therapeutic apparatus and the conventional CO₂ laser–based therapeutic apparatus. When operated under the single spot mode and at the same energy level, the novel CO₂ laser–based gynecological therapeutic apparatus created holes that could reach the greater depth. In addition, the laser spot size of the new apparatus was more constant. Moreover, there were no significant differences in the side effects between the new apparatus and the conventional apparatus. The results indicate that the novel CO₂ laser–based gynecological therapeutic apparatus exhibits better stability in comparison to the conventional CO₂ laser–based therapeutic apparatus.