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Clinical Reviews in Allergy & Immunology

Issue 1/2025

Content (113 Articles)

Group 3 Innate Lymphoid Cells: A Potential Therapeutic Target for Steroid Resistant Asthma

Marzhan Berkinbayeva, Wenjing Gu, Zhifeng Chen, Peisong Gao

Regulatory Roles of SWI/SNF Chromatin Remodeling Complexes in Immune Response and Inflammatory Diseases

  • Review

Shunan Sun, Yu Chen, Yuzhen Ouyang, Zhenwei Tang

Olfactory Dysfunction in Allergic Rhinitis

Xinyu Zhang, Yian Zhou, Zheng Liu, Yang Liu

Copy Number Variation in Asthma: An Integrative Review

Fernanda Mariano Garcia, Valdemir Pereira de Sousa, Priscila Pinto e Silva-dos-Santos, Izadora Silveira Fernandes, Faradiba Sarquis Serpa, Flávia de Paula, José Geraldo Mill, Maria Rita Passos Bueno, Flávia Imbroisi Valle Errera

Exosomes in Autoimmune Diseases: A Review of Mechanisms and Diagnostic Applications

Lina Duan, Wanying Lin, Yi Zhang, Lingyue Jin, Jie Xiao, Haifang Wang, Shuyin Pang, Hongxia Wang, Dehua Sun, Ying Gong, Haixia Li

Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective

Jing Pan, Siji Chen, Xianzhen Chen, Yinjing Song, Hao Cheng

TTC7A Variants Results in Gastrointestinal Defects and Immunodeficiency Syndrome: Case Series and Literature Review

Zhaowei Huang, Xiufang Zhi, Qiuyu Geng, Xiaoqi Yuan, Xiaoxia Zhao, Qi Qin, Jingan Lou, Fan Tong, Jinfa Tou, Dengming Lai

Short-Chain Fatty Acids: Promising Therapeutic Targets for Respiratory Syncytial Virus Infection

Mingxin Liang, Qinqin Dong, Weiyi Wu, Juan Fan

Immunological Effects of Electronic Cigarette Use: A Review of Current Evidence

Katarzyna Zima, Aleksandra Bogucka, Miłosz Wojtas, Magdalena Zabielska-Kaczorowska

Macrophages Unmasked: Their Pivotal Role in Driving Atherosclerosis in Systemic Lupus Erythematosus

Chao Wang, Bingxing Chen, Xiaochen Yu, Xiuru Guan

Allergens in Atopic Dermatitis

Jiayan Zhang, Guofang Li, Qiuyang Guo, Yijun Yang, Jinxiang Yang, Xiaobo Feng, Zhirong Yao

Nanotechnology-Based Therapeutics for Airway Inflammatory Diseases

  • Open Access
  • Review

Limei Cui, Yujuan Yang, Yan Hao, Hongfei Zhao, Yu Zhang, Tong Wu, Xicheng Song

Clinical and Pathophysiological Tangles Between Allergy and Autoimmunity: Deconstructing an Old Dichotomic Paradigm

Giuseppe A. Ramirez, Chiara Cardamone, Sara Lettieri, Micaela Fredi, Ilaria Mormile

Emerging Mechanisms and Biomarkers Associated with T-Cells and B-Cells in Autoimmune Disorders

  • Review

Azhagu Madhavan Sivalingam

Lipid Metabolism: An Emerging Player in Sjögren’s Syndrome

Keni Chang, Peiming Luo, Zizhen Guo, Lufei Yang, Jincheng Pu, Fang Han, Feiyang Cai, Jianping Tang, Xuan Wang

Crosstalk Between the Skin Environment and Microbial Community in Immune-Related Skin Diseases

Kecheng Liu, Shuting Deng, Yuan Zhou, Beilei Xu, Yu Zhang, Wei Li, Xiaochun Liu, Xu Yao

Allergic Reactions in Dental Practice: Classification of Medicines, Mechanisms of Action, and Clinical Manifestations

Maria Zofia Lisiecka

Age-Associated B Cells in Autoimmune Diseases: Pathogenesis and Clinical Implications

Guangyang Xie, Xiaojing Chen, Yixia Gao, Ming Yang, Suqing Zhou, Liwei Lu, Haijing Wu, Qianjin Lu

Multi-omics in Allergic Rhinitis: Mechanism Dissection and Precision Medicine

Yan Hao, Yujuan Yang, Hongfei Zhao, Ying Chen, Ting Zuo, Yu Zhang, Hang Yu, Limei Cui, Xicheng Song

Immunomodulatory Significance of Mast Cell Exosomes (MC-EXOs) in Immune Response Coordination

  • Open Access
  • Review

Daniel Elieh-Ali-Komi, Farzaneh Shafaghat, Shamila D. Alipoor, Tohid Kazemi, Dmitrii Atiakshin, Polina Pyatilova, Marcus Maurer

Mesenchymal Stromal Cell-Based Therapy: A Promising Approach for Autoimmune Diseases

  • Review

Liming Li, Yong He, Junpeng Zhao, Huiqi Yin, Xiwei Feng, Xinyu Fan, Wei Wu, Qianjin Lu

Immune and Non-immune Interactions in the Pathogenesis of Androgenetic Alopecia

Yu Xiao, Yi Zhang, Shuting Deng, Xueyuan Yang, Xu Yao

Review of the Pathophysiology and Clinical Manifestations of 22q11.2 Deletion and Duplication Syndromes

Jeremy Purow, Lauren Waidner, Hanadys Ale

Hereditary Angioedema with Normal C1 Inhibitor: an Updated International Consensus Paper on Diagnosis, Pathophysiology, and Treatment

Bruce L. Zuraw, Konrad Bork, Laurence Bouillet, Sandra C. Christiansen, Henriette Farkas, Anastasios E. Germenis, Anete S. Grumach, Allen Kaplan, Alberto López-Lera, Markus Magerl, Marc A. Riedl, Adil Adatia, Aleena Banerji, Stephen Betschel, Isabelle Boccon-Gibod, Maria Bova, Henrik Balle Boysen, Teresa Caballero, Mauro Cancian, Anthony J. Castaldo, Danny M. Cohn, Deborah Corcoran, Christian Drouet, Atsushi Fukunaga, Michihiro Hide, Constance H. Katelaris, Philip H. Li, Hilary Longhurst, Jonny Peter, Fotis Psarros, Avner Reshef, Bruce Ritchie, Christine N. Selva, Andrea Zanichelli, Marcus Maurer

The Role of Coagulation/Fibrinolysis Biomarkers in Pathophysiology, Disease Severity, and Treatment Response in Patients with Urticaria: A Scoping Review

Hai-yan Qin, Xian-jun Xiao, Pei-wen Xue, Di Qin, Si-qi Wang, Ying Li, Yun-zhou Shi, Li-Tao Pan

Th17 Response in Uveitis: A Double-Edged Sword in Ocular Inflammation and Immune Regulation

Yuan Zong, Xue Tong, Wai Po Chong

The Role of IL-17 in Systemic Autoinflammatory Diseases: Mechanisms and Therapeutic Perspectives

Jingyuan Zhang, Min Shen

The Role of Lactate and Lactylation in the Dysregulation of Immune Responses in Psoriasis

Xinxin Wu, Changya Liu, Caiyun Zhang, Le Kuai, Sheng Hu, Ning Jia, Jiankun Song, Wencheng Jiang, Qilong Chen, Bin Li

The Role of M6A Modification in Autoimmunity: Emerging Mechanisms and Therapeutic Implications

Liyun Xu, Tian Shen, Yongzhen Li, Xiaochuan Wu

Implication of Immunobiological Function of Melanocytes in Dermatology

Hejuan Zhang, Maomei Xia, Hongyang Li, Xuesi Zeng, Hong Jia, Wei Zhang, Jia Zhou

Immune Memory: A New Frontier in Treating Recurrent Inflammatory Skin Diseases

Hang Yin, Jianru Chen, Chunying Li

The Impact of Menopause on Autoimmune and Rheumatic Diseases

Francesca Motta, Nicoletta Di Simone, Carlo Selmi

Emerging Contaminants: An Important But Ignored Risk Factor for Psoriasis

Leyi Huang, Yinli Zhou, Hui Xiao, Yajia Li, Zhiru Zhou, Ziyi Xiao, Yixuan Tong, Kun Hu, Yehong Kuang, Minxue Shen, Yi Xiao, Xiang Chen

Neutrophils: a Central Point of Interaction Between Immune Cells and Nonimmune Cells in Rheumatoid Arthritis

Zhaoran Wang, Yi Jiao, Wenya Diao, Tong Shi, Qishun Geng, Chaoying Wen, Jiahe Xu, Tiantian Deng, Xiaoya Li, Lu Zhao, Jienan Gu, Tingting Deng, Cheng Xiao

The Impact of Mast Cells on the Anatomy, Cellular Communication, and Molecular Immune Network of Lymph Nodes

Daniel Elieh-Ali-Komi, Marcus Maurer, Frank Siebenhaar

Maternal Immune Activation: Implications for Congenital Heart Defects

Sixing Wang, Zilin Mei, Jin Chen, Kai Zhao, Ruize Kong, Lana McClements, Huiping Zhang, Aihua Liao, Chunyan Liu

Molecular Allergology: Epitope Discovery and Its Application for Allergen-Specific Immunotherapy of Food Allergy

Fei Huan, Shuai Gao, Yi Gu, Lingna Ni, Mingxuan Wu, Yongpeng Li, Meng Liu, Yang Yang, Anfeng Xiao, Guangming Liu

Effectiveness and Safety of Nemolizumab in Patients with Prurigo Nodularis: a Systematic Review and Meta-Analysis of Randomized Controlled Trials

Ahsan Raza Raja, Zoha Zahid Fazal, Aisha Sethi

Epigenetic Modifications in Vitiligo

Xin Huang, Jing Zhu, Tianqi Wei, Lingling Luo, Chengrang Li, Ming Zhao

Targeting B Cells for the Treatment of Idiopathic Inflammatory Myopathy

Tao Liu, Bo Chen, Geng Yin, Qibing Xie

Osteoimmunology: Crosstalk Between T Cells and Osteoclasts in Osteoporosis

Zeyao Lu, Peilun Xiao, Shijia Liu, Chongjun Huang, Weishang Li, Yuanheng Mao, Ying Xu, Ye Tian

Exploring Gut Microbiota in Systemic Lupus Erythematosus: Insights and Biomarker Discovery Potential

Lingyue Jin, Jie Xiao, Yuhong Luo, Lina Duan, Ying Gong, Yao Li, Haifang Wang, Yurong Qiu, Hongxia Wang, Weinan Lai, Haixia Li

Inhalant Mediated Allergy: Immunobiology, Clinical Manifestations and Diagnosis

Ki Lam, Elaine Au, W. K. Ip, Jenna K. Tam, Patrick S. C. Leung

Targeting IL-13 and IL-4 in Asthma: Therapeutic Implications on Airway Remodeling in Severe Asthma

Lina Sahnoon, Khuloud Bajbouj, Bassam Mahboub, Rifat Hamoudi, Qutayba Hamid

Questionnaire for Clinical Diagnosis of House Dust Mite’s Allergy Approved by Delphi Consensus

Angelica Tiotiu, Fulvio Braido, Krysztof Kowal, Guillermo Guidos Fogelbach, Herberto Chong Neto, Juan Carlos Ivancevich, Daniela Muti, Francisco-Javier Gonzalez-Barcala, Paschalis Steiropoulos, Silviya Novakova, Denislava Nedeva, Plamena Novakova, Stefan Mihaicuta, Jonathan Bernstein, Arzu Yorgancioglu, Pierachille Santus, Andras Bikov, Giorgio Walter Canonica, Charles Pilette

Mechanisms and Therapeutic Implications of EZH2 in Nasal Diseases

Jiani Li, Meng Wang, Jing Yang, Zhiwei Cao, Zhaowei Gu, Yunxiu Wang

Molecular Diagnosis to IgE-mediated Wheat Allergy and Wheat-Dependent Exercise-Induced Anaphylaxis

Witchaya Srisuwatchari, Kantima Kanchanapoomi, Punchama Pacharn

Neutrophilic Urticarial Dermatosis: A Window into Systemic Inflammation and Autoimmune Disorders

Xiaoxuan Cai, Yihe Zheng, Changyi Yang, Jiali Xu, Hong Fang, Jianjun Qiao

Atopic Dermatitis: The Relationship Between Immune Mediators and Skin Lipid Barrier

Huayan You, Yunsheng Liang

Macrophage-Centric Immunometabolic Crosstalk in Alopecia Areata Pathogenesis: Mechanisms and Therapeutic Implications

Xu Liu, Xiuzu Song

Sex Bias in Systemic Sclerosis: from Clinical to Immunological Differences

Lazaros I. Sakkas, Dimitrios P. Bogdanos, Ian C. Chikanza

Allergic Rhinitis is Associated with Increased Suicidality: A Systematic Review and Meta-Analysis

Simon Høj, Frederik Kronvold Nielsen, Bo Chawes, Vibeke Backer, Allan Linneberg, Simon Francis Thomsen, Torben Sigsgaard, Howraman Meteran

IL-17-Related Pathways and Myeloid Cell Function are Involved in the Mechanism of Sublingual Immunotherapy with Artemisia annua for Seasonal Allergic Rhinitis

Yan Zhao, Song Mei, Shuang Yao, Shiru Cai, Peng Zhang, Hongfei Lou, Luo Zhang

Recombinant BCG Expressing IL-12 as A Novel Immunomodulatory Strategy for Allergic Asthma: Opportunities and Challenges

Romina Campos-Povea, Enrique González-Madrid, Tays Troncoso-Bravo, Hernán F. Peñaloza, Pablo A. González, Susan M. Bueno, Alexis M. Kalergis

B Cell Tolerance and Obstetric Antiphospholipid Syndrome

Brita Laht, Suraj Timilsina, M. Eric Gershwin, Raivo Uibo

Promising Targeted Therapies for Hemophagocytic Lymphohistiocytosis: A Translational Perspective Based on Immunopathology

Yuanyuan Yang, Songtao Tu, Hongwei Peng, Jialiang Lu, Hua Yu, Yulan Zhou, Xiaowu Dong, Fei Li

Describing Clinical Characteristics and Treatment Course of Patients with Hereditary Alpha-tryptasemia: A Single-center Study

Meghan Matheny, Maria P. Henao, Taha Al-Shaikhly

Novel Findings on the Development and Immunological Functions of Palatine Tonsils

Nadiya Abulikemu, Zheng Liu, Yang Liu

Current Understanding of Epithelial-Derived Alarmins in Chronic Rhinosinusitis with Nasal Polyps

Fuying Cheng, Yizhang Wang, Yingqi Gao, Chen Zhang, Qianqian Zhang, Jiani Chen, Yumin Zhou, Le Shi, Li Hu, Huan Wang, Yaguang Zhang, Xicai Sun

Aberrant Activation of Mast Cells: Molecular Mechanisms and Targets for Intervention

Jinghao Wen, Zehao Lan, Liting He, Hai Long

Towards a Multi-omics Understanding of Anaphylaxis: Insights into Pathogenesis and Biomarker Identification

Manca Svetina, Tanja Kunej, Peter Korošec, Matija Rijavec

Integrating Machine Learning into Myositis Research: a Systematic Review

Christian Juarez-Gomez, Andrea Aguilar-Vazquez, Emiliano Gonzalez-Gauna, Gabriela Paola Garcia-Ordoñez, Beatriz Teresita Martin-Marquez, Cynthia-Alejandra Gomez-Rios, Jose Becerra-Jimenez, Arahi Gaspar-Ruiz, Monica Vazquez-Del Mercado

The Treatment of Primary Biliary Cholangitis: Time for Personalized Medicine

Xinyi Men, Yansheng Liu, Han Zhao, Bingrui Xie, Changcun Guo, Patrick S. C. Leung, Suraj Timilsina, M. Eric Gershwin, Yulong Shang, Ying Han

The c.64 + 2 T > A Founder Variant Hits Home: Report on 14 Patients Expands the Phenotypic Landscape of Inherited ARPC1B Deficiency — a Comparative Analysis

Dharmagat Bhattarai, Aaqib Zaffar Banday, Pratap Kumar Patra, Ramji Baral, Chakshu Chaudhry, Katta M. Girisha, Jolan E. Walter, Ganga Narasimhan, Bénédicte Neven, Asbjørg Stray-Pedersen, Kathleen E. Sullivan

Advances in Shellfish Allergy Therapy: From Current Approaches to Future Strategies

Sahel Heidari, Thimo Ruethers, Shaymaviswanathan Karnaneedi, Lydia Wong Su Yin, Andreas Ludwig Lopata

Atopic Dermatitis beyond Eczema: A Review on its Systemic Impact through Pruritus and Associated Comorbidities

Alvaro Prados-Carmona, Husein Husein-ElAhmed, Francisco J. Navarro-Triviño, Ricardo Ruiz-Villaverde

Neurological Complications in Inborn Errors of Immunity: A Scoping Review of Clinical Spectrum, Pathophysiological Mechanisms, and Therapeutic Strategies

Ningkun Xiao, Xinlin Huang, Linzi Chen, Wanli Zang, Maosen Guan, Tianjiao Li, Irina Tuzankina, Valery Chereshnev, Guojun Liu

UHRF1 in Immune Regulation and Diseases: Mechanisms and Therapeutic Implications

Tingyue Guo, Yihui Ruan, Bo Wu, Shulan Sun, Hongxu Liu

Residential Proximity to Major Roadways and Risk of Allergic Respiratory Outcomes: A Systematic Review and Meta-analysis

Qinchi Yu, Zihao Guo, Lijun Bai, Huimeng Liu, Cuiyao Xie, Dandan Liu, Yuxue Chang, Yaxin Wang, Ming Li, Jian Lei, Shaowei Wu

Efficacy and Safety of Biologics for Systemic Lupus Erythematosus (SLE): A Systematic Review and Network Meta-Analysis

Ziyan Ding, Hui Zhang, Fan Huang, Yian Liu, Qian Zhou, Dingyuan Hu, Liming Chen, Yanting Li, Rui Ding, Xiaoyan Nie, Yi Fang

Aquaporins in Allergic Response: A New Player

Adriano Martínez Villarreal, Valeria Grattz Lamadrid, Andrés Sanchez, Marlon Múnera

Circadian Clock Disruption and Non-type 2 Asthma: A Hypothesis-Driven Perspective on Immune, Epithelial, and Steroid Response

Haohua Huang, Xiaoxiao Jiang, Qian Du, Hua Liao, Shaoxi Cai, Hangming Dong

Susac Syndrome: A Systematic Review and Survival Analysis

  • Review

Gian Marco Pace, Luca Canali, Domenico Villari, Giuseppe Spriano, Giuseppe Mercante, Isabelle Mosnier, Daniele Bernardeschi, Giovanni Colombo, Matteo Di Bari

Factors Influencing Treatment Adherence in Chronic Spontaneous Urticaria: A Systematic Review

Aditya Joshi, Lauren Gawey, Muhammad Rahman, Raveena Ghanshani, Khiem A. Tran, Adam Friedman, Jennifer L. Hsiao, Vivian Y. Shi

Furry Animal Allergy: Lipocalins, Serum Albumins, and Secretoglobins—Cross-Reactivity, Diagnosis, and Management Strategies

Weronika Gromek, Natalia Kołdej, Marcin Kurowski, Emilia Majsiak

Intestinal Neuroimmunology and Its Implications in Food Allergy

Hongjie Chen, Jing Yang

Immunomodulatory Roles of Faecalibacterium prausnitzii and Akkermansia muciniphila in Autoimmune Diseases: Mechanistic Insights and Therapeutic Potential

Eui Jeong Han, Ji-Seon Ahn, Yoon Jung Chae, Hea-Jong Chung

Correction: Towards a Multi-omics Understanding of Anaphylaxis: Insights into Pathogenesis and Biomarker Identification

Manca Svetina, Tanja Kunej, Peter Korošec, Matija Rijavec

Systemic Psoriasis: From Molecular Mechanisms to Global Management Strategies

Suriyaraj Shanmugasundaram Prema, Deepankumar Shanmugamprema

The Role of Solute Carriers in the Metabolic Reprogramming of Skin Diseases

Yihui Chen, Cong Peng, Xiang Chen, Jie Li

Behçet’s Disease In Children And Adults Of Sub-Saharan Ancestry: A Systematic Review And Meta-Analysis

  • Open Access
  • Review

Benoit Suzon, Arthur Felix, Fabienne Louis-Sidney, Esther Dalmasie, Sunniva Donat, Christophe Deligny, Aurore Abel, Eleonore de Fritsch

Islet Tissue Macrophages in Immunity Homeostasis and Type 1 Diabetes

Yan Wang, Zhaoran Wang, Wenya Diao, Tong Shi, Jiahe Xu, Tiantian Deng, Chaoying Wen, Jienan Gu, Tingting Deng, Sixuan Wang, Cheng Xiao

Malignancy in Idiopathic Inflammatory Myopathies: Recent Insights

Hongzheng Wu, Xiaomeng Li, Honglin Xu, Zhan Li, Futai Feng, Jingdi Zhang, Zhixin Xu, Haoxi Ni, Ye Guo, Yongzhe Li

Aberrant Enhancer Regulation, Phase Separation, and Autoimmune Diseases

Huihui Hou, Yueqi Qiu, Ming Zhao

Decoding Allergic Conjunctivitis: Latest Perspectives on Etiological Drivers and Immunopathological Mechanisms

Jiayu Bao, Ya Wen, Lei Tian, Ying Jie

The Ubiquitin–Proteasome System in Asthma: Mechanisms and Therapeutic Possibilities

Shuangyu He, Siqi Wen, Zhen Wang, Yonggang Qu, Chongyu Xu, Danni Li, Jiapeng Hu

Targeting IL-4/IL-13 Signaling Pathways in Chronic Rhinosinusitis with Nasal Polyps: From Mechanisms to Therapies

Jiani Chen, Chen Zhang, Qianqian Zhang, Fuying Cheng, Yizhang Wang, Shirui Xue, Yufei Yang, Wenwen Guo, Juan Liu, Kai Xue, Yaguang Zhang, Dehui Wang, Li Hu, Huan Wang, Xicai Sun

Coexistence of VEXAS Syndrome and Chronic Hepatitis B Virus Infection: a Case Report and Literature Review

Kailong Lin, Yanqing Wang, Jiamin Song, Bing Li, Xu Wang, Jiale Tian, Yu Zeng, Muhammad Shahzad, Jianping Tang, Xuan Wang

Recent Advances in Oral Immunotherapy for Food Allergies

Sakura Sato, Ken-ichi Nagakura, Noriyuki Yanagida, Motohiro Ebisawa

Glandular Manifestations of the Head and Neck in ANCA-Associated Vasculitides: Data from a National Cohort and Systematic Review

Nicolas Duhamel, Xavier Puéchal, Thomas Le Gallou, Julie Chezel, Alban Deroux, Céline Roussin, Jérémy Keraen, Claire De Moreuil, Pierre-André Jarrot, Mathieu Gerfaud-Valentin, François Maurier, Julien Campagne, Isabelle Melki, Sara Melboucy, Sophie Nagle, Benjamin Terrier, Nihal Martis

PD-1/PD-L1 Cancer Immunotherapeutics Reshape Tumor Microenvironment – Clinical Evidence and Molecular Mechanisms for AI-based Precision Medicine

Yen-Yi Lin, Jeak Ling Ding, Hsieh-Tsung Shen, Yu-Ming Lin, Edeline Clarissa Adhidjaja, Shu-Chun Chang

Immunodeficiencies in Adults: Key Considerations for Diagnosis and Management

Jean Regina, Jacqueline Doms, Eleftheria Kampouri, Christel Gerber, Oriol Manuel, Pierre-Alexandre Bart, Fabio Candotti, Denis Comte

Next-Generation Allergen-Specific Immunotherapy for Food Allergy

Joyce Z. X. Lee, Jason K. C. Sit, Nicki Y. H. Leung, Ka Hou Chu, Patrick S. C. Leung, Ting Fan Leung, Christine Y. Y. Wai

Investigating Non-celiac Wheat Sensitivity: A Comprehensive Review of Pathophysiology Underlying Clinical Implications

Anays Piotin, Frédéric de Blay

The Pathogenic Role of T Cell Metabolism and its Effect on Immune Senescence in Autoimmune Diseases and Infection

Huan Yin, Suqing Zhou, Kai Shen, Hui Chen, Ming Yang, Yaxiong Deng, Christopher Chang, Haijing Wu

The Genomics/Genetics of Primary Biliary Cholangitis: The Case for a Functional SNP rs10893900 in ETS1/FLI1 and Review of the Literature

Mingming Zhang, Chan Wang, Yexi Huang, Lu Wang, Yaping Dai, Yuzhang Jiang, Chongxu Han, Yuhua Gong, Li Li, Ye Tian, Wenyan Tian, Runhao Lin, Shuna Tong, Meilin Wang, Xiong Ma, Fang Qiu, Zhexiong Lian, M. Eric Gershwin, Xingjuan Shi, Weichang Chen, Xiangdong Liu

Multi-target Effects of Short-Chain Fatty Acids for Obesity-Related Asthma: Interventional Potential and Challenges

Mingxin Liang, Lan Li, Juan Fan

Inflammation and Immune Pathways in Myopia: An Overview on Pathomechanisms and Treatment Prospects

Jing Zhang, Koju Kamoi, Yuan Zong, Mingming Yang, Yaru Zou, Kyoko Ohno-Matsui

COVID-19-associated Autoimmune and Inflammatory Diseases: Molecular Mechanisms and the Role of IVIG Therapy

Sukanya Bordoloi, Suraj C. Singh, Jagadeesh Bayry

CAR T Cell Therapy for Rheumatoid Arthritis

Michael Freeley

The Immunogenic Role of Self-DNA in T Cell Immunity

Jiaxin Lei, Mengdi Liu, Xiao Huang, Xingyu Zhai, Huiyan Ji, Zhenke Wen

Microorganisms, Microbial Metabolites and Precision Nutrition: Targeting the Gut-Skin Axis for Immune Microenvironment Remodeling in Atopic Dermatitis

Sibo Liu, Qingxue Chen, Yue Gu, Huan Lei, Bailiang Li, Qi Qin

Chimeric Antigen Receptor T Cell Therapy in Systemic Lupus Erythematosus: Mechanisms, Clinical Advances, and Future Directions a Comprehensive Review

Ahmad Matarneh, Bayan Matarneh, Omar Salameh, Abdelrauof Akkari, Nasrollah Ghahramani, Naman Trivedi

Utility of in Vivo and Ex-vivo Models in Food Allergy Research: Lessons for Shrimp Allergy

Minh Kieu Le, Binh Vu Thanh Luong, Tuan Anh Tran, Ngoc Thi Nguyen, Dinh Kieu Diem Truong, Hoang Kim Tu Trinh

Common Variable Immunodeficiency Disorders: A perspective from New Zealand

Rohan Ameratunga, Hilary J. Longhurst, Klaus Lehnert, Euphemia Leung, Richard Steele, See-Tarn Woon

Bridging the Gap in Secondary Antibody Deficiencies: Current Evidence and Unmet Needs in Diagnosis and Management with Immunoglobulin Replacement

Andy Ka Chun Kan, Ben Chun Yin Chan, Chak Sing Lau, Philip H Li

Pathophysiologic Mechanisms and Targeted Treatments Associated with the Nervous System in Cutaneous Allergic Diseases

Hantian Zhang, Weiyi Xiang, Yi Tong, Xian Jiang, Linghong Guo

A Multisectoral Study of Mpox Epidemiology, Resistance Surveillance, and Policy Gaps: Toward a One Health Framework

Durjoy Mistry, Mehjabin Hossain, B. S. Diba, J. D. Plabon, M. A. Shams, M. T. Rahman, A. S. M. Bakibillah

Immunological Mechanisms and Outcomes of T-cell-Targeted Immunotherapy in Food Allergy: A Systematic Review

Svetlana Fesenko, Stella A. Nicolaou

Potential Mechanisms and Hypotheses for Pathogenic Microorganisms Triggering Kawasaki Disease

Jinhan Yu, Linlin Cheng, Haoting Zhan, Yuan Huang, Siyu Wang, Haolong Li, Yongmei Liu, Yingchun Xu, Ye Guo, Yongzhe Li

Association between COVID-19 and New-Onset Autoimmune Diseases: Updated Systematic Review and Meta-Analysis of 97 Million Individuals

Chih-Chen Tzang, Henry Sheng, Vicky Fu-Hsuan Kuo, Chiao-An Luo, Tzu-An Lin, Yi-Ting Lee, Ewen Shengyao Huang, Pei-Hsun Wu, Bor-Show Tzang, Tsai-Ching Hsu

Immunopathogenesis and Therapeutics of Systemic Lupus Erythematosus: an Integrative Review

Qian Lyu, Huan Zou, Shen Hu

Comparative Efficacy of Combined and Standalone Oral Immunotherapies for Peanut Allergy: a Bayesian Network Meta-Analysis of RCTs

Xinyu Tian, Shuang Liu, Lisha Li, Kai Guan

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Keynote webinar | Spotlight on progress in colorectal cancer

On-demand video coming soon

CRC remains a major global health burden, but advances in screening, treatment, and lifestyle-based prevention continue to reshape clinical practice. Gain insights into how the latest research can be leveraged to optimize patient care across the CRC continuum.

Prof. Antoni Castells
Prof. Harpreet Wasan
Prof. Edward Giovannucci
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Keynote webinar | Spotlight on functional neurological disorder

FND perplexes and frustrates patients and physicians alike. Limited knowledge and insufficient awareness delays diagnosis and treatment, and many patients feel misunderstood and stigmatized. How can you recognize FND and what are the treatment options?

Prof. Mark Edwards
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Colon cancer illustration/© (M) KATERYNA KON / SCIENCE PHOTO LIBRARY / Getty Images, Human brain illustration/© (M) CHRISTOPH BURGSTEDT / SCIENCE PHOTO LIBRARY / Getty Images