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Rheumatology Chronic Pain Syndrome

Chronic Pain Syndrome

Lumbar sympathetic block to treat CRPS in a toddler

After non-invasive measures failed, a lumbar sympathetic block performed with extreme caution alleviated complex regional pain syndrome in this 18-month-old.

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Editor's Choice

Self-guided digital behavioral therapy for fibromyalgia

A 12-week self-guided digital acceptance and commitment therapy program is safe and effective for adults with fibromyalgia, improving associated symptoms including fatigue and sleep disturbance.

Caution needed when prescribing gabapentinoids in people with COPD

Gabapentinoid use by patients with chronic obstructive pulmonary disease for epilepsy, neuropathic pain, or other chronic pain is associated with an increased risk for severe exacerbations.

Illness uncertainty in hypermobile Ehlers-Danlos syndrome

Diagnosis of hypermobile EDS takes an average of 22 years after initial symptom presentation. This review explores patients’ experience of illness uncertainty to provide practical recommendations for clinical care.

Neurostimulation therapies for chronic pain

About 20% of adults have chronic pain. This review analyses the effectiveness of non-invasive and invasive neurostimulation therapies for patients who fail to attain relief from extensive pharmacological treatment.

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Case Studies

Lumbar sympathetic block to treat CRPS in a toddler

After non-invasive measures failed, a lumbar sympathetic block performed with extreme caution alleviated complex regional pain syndrome in this 18-month-old.

Current Reviews

Chronic Pain and Obsessive–Compulsive Disorder: A Scoping Review

The impetus for this study came about through clinical observations of clients presenting with both Obsessive–Compulsive Disorder (OCD) and Chronic Pain (CP) through work in Community Pain Management Services. While being aware of substantial and …

Small Fibre Pathology in Fibromyalgia: A review

Fibromyalgia syndrome (FMS) presents a complex and challenging disorder in both the diagnosis and treatment, with emerging evidence suggesting a role of small fibre pathology (SFP) in its pathophysiology. The significance of the role of SFP in FMS …

Brain modulatory effects of rehabilitation interventions in fibromyalgia: a systematic review of magnetic resonance imaging studies

Fibromyalgia (FM) is characterised by widespread pain, cognitive impairment, and fatigue, imposing a considerable burden of disability worldwide [ 1 ]. Although the mechanisms underlying FM remain unclear, altered functional connectivity (FC) and …

Water-based interventions in rheumatic diseases: mechanisms, benefits, and clinical applications

Chronic pain and restricted mobility, hallmark features of rheumatic diseases, substantially affect patients’ quality of life, often resulting in physical disability and emotional distress. Given the long-term nature of these conditions, there is …

Further Reading

Global research trends on fibromyalgia and exercise: a ten-year Web of Science-based bibliometric analysis

Fibromyalgia causes widespread pain, exhaustion, and cognitive deficits, lowering sufferers’ quality of life. Exercise supports the management of fibromyalgia by reducing pain and improving mood. This study examines global fibromyalgia and …

Evaluation of abdominal and lumbar multifidus muscles thickness and relation to endurance, pain, fatigue and functional mobility in patients with Fibromyalgia syndrome: a case-control study

Fibromyalgia (FM) is a chronic syndrome described by persistent and generalized musculoskeletal pain. Patients also present with comorbid symptom such as fatigue, sleep disturbance, morning stiffness, cognitive problems and psychosomatic disorder …

Diagnostic utility of deep tendon reflex responses in rectus femoris and triceps brachii in fibromyalgia: a clinical and electrophysiological study

The aim of this study was to evaluate deep tendon reflex responses and associated electrophysiological parameters of the muscles in patients with fibromyalgia. This cross-sectional study included 38 patients with fibromyalgia and 32 age- and …

Therapeutic approach to fibromyalgia: a consensus statement on pharmacological and non-pharmacological treatment from the neuropathic pain special interest group of the Italian neurological society

Fibromyalgia (FM) is a disabling disease characterized by chronic widespread pain, fatigue, sleep disturbances, cognitive failure, and headaches. While the diagnostic criteria are well established [ 1 ], the pathophysiology is still unknown. The …

Related topics

Self-guided digital behavioral therapy for fibromyalgia

A 12-week self-guided digital acceptance and commitment therapy program is safe and effective for adults with fibromyalgia, improving associated symptoms including fatigue and sleep disturbance.

Read more