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09-05-2024 | Chronic Kidney Disease | Original Article

Characterization of CKD illness representation profiles using patient-level factors

Authors: Eleanor Rivera, Nathan Tintle, Raymond R. Townsend, Mahboob Rahman, Sarah J. Schrauben, Maya N. Clark-Cutaia, Mary Hannan, James P. Lash, Katherine Wolfrum, Celestin Missikpode, Karen B. Hirschman

Published in: Journal of Nephrology | Issue 3/2024

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Abstract

Background

Illness perceptions are the unique perspective individuals have on their illness, based on their context and experiences, and are associated with patient outcomes including coping and adherence. The purpose of this study was to explore characteristics that may be driving membership in illness perceptions cluster groups for adults with chronic kidney disease (CKD).

Methods

This study was conducted within the multicenter longitudinal Chronic Renal Insufficiency Cohort (CRIC) Study. Cross-sectional data were collected and combined with CRIC data. Illness perceptions were measured using the Revised Illness Perception Questionnaire. Clustering analysis was conducted in R, and bivariate analysis including linear regression was performed in STATA 16.

Results

The sample (n = 197) had a mean age of 68, was 52% women, 53% non-White, and mean estimated glomerular filtration rate (eGFR) 56 ml/min/1.73 m2. Three cluster groups were identified, labeled as “Disengaged” (n = 20), “Well-Resourced” (n = 108), and “Distressed” (n = 69). The “Disengaged” group was characterized by low CKD knowledge, many recent hospitalization days, and the lowest perceived CKD burden. The “Well-Resourced” group was characterized by the highest levels of education, CKD knowledge, optimism, and medication adherence. The “Distressed” group was characterized by the highest levels of depression scores, comorbidity burden, CKD burden, CKD symptoms, and lowest optimism. Group membership significantly predicted the number of hospitalization days in adjusted analyses.

Conclusions

Illness perceptions groups are associated with number of hospitalization days but are independent of many patient characteristics. Illness perceptions data could be used to tailor care for specific patients at risk for poor health outcomes.

Graphical Abstract

Appendix
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Metadata
Title
Characterization of CKD illness representation profiles using patient-level factors
Authors
Eleanor Rivera
Nathan Tintle
Raymond R. Townsend
Mahboob Rahman
Sarah J. Schrauben
Maya N. Clark-Cutaia
Mary Hannan
James P. Lash
Katherine Wolfrum
Celestin Missikpode
Karen B. Hirschman
Publication date
09-05-2024
Publisher
Springer International Publishing
Published in
Journal of Nephrology / Issue 3/2024
Print ISSN: 1121-8428
Electronic ISSN: 1724-6059
DOI
https://doi.org/10.1007/s40620-024-01955-2

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