Issue 1/2013
Content (177 Articles)
- Open Access
- Original investigation
Relationship between fluctuations in glucose levels measured by continuous glucose monitoring and vascular endothelial dysfunction in type 2 diabetes mellitus
Keiichi Torimoto, Yosuke Okada, Hiroko Mori, Yoshiya Tanaka
- Open Access
- Original investigation
Alogliptin ameliorates postprandial lipemia and postprandial endothelial dysfunction in non- diabetic subjects: a preliminary report
Yoko Noda, Toru Miyoshi, Hiroki Oe, Yuko Ohno, Kazufumi Nakamura, Norihisa Toh, Kunihisa Kohno, Hiroshi Morita, Kengo Kusano, Hiroshi Ito
- Open Access
- Original investigation
Association between dietary phylloquinone intake and peripheral metabolic risk markers related to insulin resistance and diabetes in elderly subjects at high cardiovascular risk
Martí Juanola-Falgarona, Jordi Salas-Salvadó, Ramon Estruch, Maria P Portillo, Rosa Casas, Jonatan Miranda, Miguel A Martínez-González, Mònica Bulló
- Open Access
- Original investigation
Association of serum osteoprotegerin with vascular calcification in patients with type 2 diabetes
Atsushi Aoki, Miho Murata, Tomoko Asano, Aki Ikoma, Masami Sasaki, Tomoyuki Saito, Taeko Otani, Sachimi Jinbo, Nahoko Ikeda, Masanobu Kawakami, San-e Ishikawa
- Open Access
- Original investigation
Macrovascular complication phenotypes in type 2 diabetic patients
Giuseppe Papa, Claudia Degano, Maria P Iurato, Carmelo Licciardello, Raffaella Maiorana, Concetta Finocchiaro
- Open Access
- Original investigation
Serum osteocalcin level and its association with carotid atherosclerosis in patients with type 2 diabetes
Li Sheng, Wenjie Cao, Bingbing Cha, Zhaoping Chen, Fang Wang, Jun Liu
- Open Access
- Original investigation
Coronary aspirate TNFα reflects saphenous vein bypass graft restenosis risk in diabetic patients
Theodor Baars, Thomas Konorza, Philipp Kahlert, Stefan Möhlenkamp, Raimund Erbel, Gerd Heusch, Petra Kleinbongard
- Open Access
- Original investigation
Transient decrease in serum potassium level during ischemic attack of acute coronary syndrome: Paradoxical contribution of plasma glucose level and glycohemoglobin
Hiroshi Sekiyama, Tomohisa Nagoshi, Kimiaki Komukai, Masato Matsushima, Daisuke Katoh, Kazuo Ogawa, Kosuke Minai, Takayuki Ogawa, Michihiro Yoshimura
- Open Access
- Original investigation
Correlation between mean platelet volume and fasting plasma glucose levels in prediabetic and normoglycemic individuals
Masanori Shimodaira, Tomohiro Niwa, Koji Nakajima, Mutsuhiro Kobayashi, Norinao Hanyu, Tomohiro Nakayama
- Open Access
- Original investigation
Glycemic variability is associated with subclinical atherosclerosis in Chinese type 2 diabetic patients
Yifei Mo, Jian Zhou, Mei Li, Yuwei Wang, Yuqian Bao, Xiaojing Ma, Ding Li, Wei Lu, Cheng Hu, Minghua Li, Weiping Jia
- Open Access
- Original investigation
Prevalence and clinical characteristics of carotid atherosclerosis in newly diagnosed patients with ketosis-onset diabetes: a cross-sectional study
Lian-Xi Li, Cui-Chun Zhao, Ying Ren, Yin-Fang Tu, Jun-Xi Lu, Xing Wu, Wei-Xing Zhang, Jia-An Zhu, Mei-Fang Li, Li-Bo Yu, Yu-Qian Bao, Wei-Ping Jia
- Open Access
- Original investigation
Myocardial impulse propagation is impaired in right ventricular tissue of Zucker Diabetic Fatty (ZDF) rats
Kristine Boisen Olsen, Lene Nygaard Axelsen, Thomas Hartig Braunstein, Charlotte Mehlin Sørensen, Claus B Andersen, Thorkil Ploug, Niels-Henrik Holstein-Rathlou, Morten Schak Nielsen
- Open Access
- Original investigation
Plasma concentrations of extracellular matrix protein fibulin-1 are related to cardiovascular risk markers in chronic kidney disease and diabetes
Alexandra Scholze, Else-Marie Bladbjerg, Johannes J Sidelmann, Axel CP Diederichsen, Hans Mickley, Mads Nybo, W Scott Argraves, Peter Marckmann, Lars M Rasmussen
- Open Access
- Original investigation
Lipoprotein lipase links vitamin D, insulin resistance, and type 2 diabetes: a cross-sectional epidemiological study
Yifan Huang, Xiaoxia Li, Maoqing Wang, Hua Ning, Lima A, Ying Li, Changhao Sun
- Open Access
- Original investigation
Relationship between Advanced Glycation End Products and Plaque Progression in Patients with Acute Coronary Syndrome: The JAPAN-ACS Sub-study
Yoshifumi Fukushima, Hiroyuki Daida, Takeshi Morimoto, Takatoshi Kasai, Katsumi Miyauchi, Sho-ichi Yamagishi, Masayoshi Takeuchi, Takafumi Hiro, Takeshi Kimura, Yoshihisa Nakagawa, Masakazu Yamagishi, Yukio Ozaki, Masunori Matsuzaki
- Open Access
- Original investigation
Temporal changes in concentrations of lipids and apolipoprotein B among adults with diagnosed and undiagnosed diabetes, prediabetes, and normoglycemia: findings from the National Health and Nutrition Examination Survey 1988–1991 to 2005–2008
Earl S Ford, Chaoyang Li, Allan Sniderman
- Open Access
- Original investigation
Genetic analysis of haptoglobin polymorphisms with cardiovascular disease and type 2 diabetes in the diabetes heart study
Jeremy N Adams, Amanda J Cox, Barry I Freedman, Carl D Langefeld, J Jeffrey Carr, Donald W Bowden
- Open Access
- Original investigation
Propofol protects against high glucose-induced endothelial adhesion molecules expression in human umbilical vein endothelial cells
Minmin Zhu, Jiawei Chen, Hui Jiang, Changhong Miao
- Open Access
- Original investigation
Overweight condition and waist circumference and a candidate gene within the 12q24 locus
Claudia Gragnoli
- Open Access
- Original investigation
Cardiovascular safety of sitagliptin in patients with type 2 diabetes mellitus: a pooled analysis
Samuel S Engel, Gregory T Golm, Deborah Shapiro, Michael J Davies, Keith D Kaufman, Barry J Goldstein
- Open Access
- Original investigation
Influence of fibrinogen and C-RP on progression of peripheral arterial disease in type 2 diabetes: a preliminary report
Marijan Bosevski, Golubinka Bosevska, Lily Stojanovska
- Open Access
- Original investigation
Cardiovascular risk escalation with caloric excess: a prospective demonstration of the mechanics in healthy adults
Alok K Gupta, William D Johnson, Darcy Johannsen, Eric Ravussin
- Open Access
- Original investigation
Changes of serum angiogenic factors concentrations in patients with diabetes and unstable angina pectoris
Chun Gui, Shi-kang Li, Qin-ling Nong, Fang Du, Li-guang Zhu, Zhi-yu Zeng
- Open Access
- Original investigation
Angiotensin-converting enzyme inhibition and food restriction restore delayed preconditioning in diabetic mice
Gerry Van der Mieren, Ines Nevelsteen, Annelies Vanderper, Wouter Oosterlinck, Willem Flameng, Paul Herijgers
- Open Access
- Original investigation
Influencing factors on cardiac structure and function beyond glycemic control in patients with type 2 diabetes mellitus
Ryoko Ichikawa, Masao Daimon, Tetsuro Miyazaki, Takayuki Kawata, Sakiko Miyazaki, Masaki Maruyama, Shuo-Ju Chiang, Hiromasa Suzuki, Chiharu Ito, Fumihiko Sato, Hirotaka Watada, Hiroyuki Daida
- Open Access
- Original investigation
Metabolic predictors of ischemic heart disease and cerebrovascular attack in elderly diabetic individuals: difference in risk by age
Toshio Hayashi, Atsushi Araki, Seinosuke Kawashima, Hirohito Sone, Hiroshi Watanabe, Takashi Ohrui, Koutaro Yokote, Minoru Takemoto, Kiyoshi Kubota, Mitsuhiko Noda, Hiroshi Noto, Koichiro Ina, Hideki Nomura
- Open Access
- Original investigation
Blood glucose may be an alternative to cholesterol in CVD risk prediction charts
Julia Braun, Matthias Bopp, David Faeh
- Open Access
- Review
Diabetes, perioperative ischaemia and volatile anaesthetics: consequences of derangements in myocardial substrate metabolism
Charissa E van den Brom, Carolien SE Bulte, Stephan A Loer, R Arthur Bouwman, Christa Boer
- Open Access
- Original investigation
Impaired cardioprotective function of transplantation of mesenchymal stem cells from patients with diabetes mellitus to rats with experimentally induced myocardial infarction
Yu Liu, Zhi Li, Tao Liu, Xiaodong Xue, Hui Jiang, Jianhua Huang, Huishan Wang
- Open Access
- Original investigation
Differential impact of metabolic syndrome on subclinical atherosclerosis according to the presence of diabetes
Ki-Bum Won, Hyuk-Jae Chang, Hyeon-Chang Kim, Kyewon Jeon, Hancheol Lee, Sanghoon Shin, In-Jeong Cho, Sung-Ha Park, Sang-Hak Lee, Yangsoo Jang
- Open Access
- Original investigation
Changes in red blood cell membrane structure in type 2 diabetes: a scanning electron and atomic force microscopy study
Antoinette V Buys, Mia-Jean Van Rooy, Prashilla Soma, Dirk Van Papendorp, Boguslaw Lipinski, Etheresia Pretorius
- Open Access
- Original investigation
Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker
Sara Nunes, Edna Soares, João Fernandes, Sofia Viana, Eugénia Carvalho, Frederico C Pereira, Flávio Reis
- Open Access
- Original investigation
Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats
Márta Sárközy, Ágnes Zvara, Nóra Gyémánt, Veronika Fekete, Gabriella F Kocsis, Judit Pipis, Gergő Szűcs, Csaba Csonka, László G Puskás, Péter Ferdinandy, Tamás Csont
- Open Access
- Original investigation
High-density lipoprotein of patients with Type 2 Diabetes Mellitus upregulates cyclooxgenase-2 expression and prostacyclin I-2 release in endothelial cells: relationship with HDL-associated sphingosine-1-phosphate
Xunliang Tong, Hui Peng, Donghui Liu, Liang Ji, Chenguang Niu, Jun Ren, Bing Pan, Jianying Hu, Lemin Zheng, Yining Huang
- Open Access
- Original investigation
Intense exercise training is not effective to restore the endothelial NO-dependent relaxation in STZ-diabetic rat aorta
Mohamed Sami Zguira, Sophie Vincent, Solène Le Douairon Lahaye, Ludivine Malarde, Zouhair Tabka, Bernard Saïag
- Open Access
- Original investigation
Treatment with a copper-selective chelator causes substantive improvement in cardiac function of diabetic rats with left-ventricular impairment
Jun Lu, Beau Pontré, Stephen Pickup, Soon Y Choong, Mingming Li, Hong Xu, Gregory D Gamble, Anthony RJ Phillips, Brett R Cowan, Alistair A Young, Garth JS Cooper
- Open Access
- Original investigation
Discriminant ratio and biometrical equivalence of measured vs. calculated apolipoprotein B100 in patients with T2DM
Michel P Hermans, Sylvie A Ahn, Michel F Rousseau
- Open Access
- Original investigation
Effects of sitagliptin beyond glycemic control: focus on quality of life
Yoshiko Sakamoto, Jun-ichi Oyama, Hideo Ikeda, Shigetaka Kuroki, Shigeki Gondo, Taketo Iwamoto, Yasufumi Uchida, Kazuhisa Kodama, Atsushi Hiwatashi, Mitsuhiro Shimomura, Isao Taguchi, Teruo Inoue, Koichi Node
- Open Access
- Original investigation
Antidiabetic treatment restores adiponectin serum levels and APPL1 expression, but does not improve adiponectin-induced vasodilation and endothelial dysfunction in Zucker diabetic fatty rats
Peter M Schmid, Markus Resch, Christian Schach, Christoph Birner, Guenter A Riegger, Andreas Luchner, Dierk H Endemann
- Open Access
- Original investigation
Co-morbidity but not dysglycaemia reduces quality of life in patients with type-2 diabetes treated with oral mono- or dual combination therapy – an analysis of the DiaRegis registry
Jürgen Wasem, Peter Bramlage, Anselm K Gitt, Christiane Binz, Michael Krekler, Evelin Deeg, Diethelm Tschöpe
- Open Access
- Original investigation
20/(fasting C-peptide × fasting plasma glucose) is a simple and effective index of insulin resistance in patients with type 2 diabetes mellitus: a preliminary report
Tsuyoshi Ohkura, Hideki Shiochi, Youhei Fujioka, Keisuke Sumi, Naoya Yamamoto, Kazuhiko Matsuzawa, Shoichiro Izawa, Hiroshi Kinoshita, Hiroko Ohkura, Masahiko Kato, Shin-ichi Taniguchi, Kazuhiro Yamamoto
- Open Access
- Original investigation
Prognostic value of early in-hospital glycemic excursion in elderly patients with acute myocardial infarction
Gong Su, Shu-hua Mi, Zhao Li, Hong Tao, Hong-xia Yang, Hong Zheng
- Open Access
- Reviewer acknowledgement
Annual acknowledgement of manuscript reviewers
Alexander Tenenbaum, Enrique Fisman
- Open Access
- Original investigation
Anti-inflammatory effects of triptolide improve left ventricular function in a rat model of diabetic cardiomyopathy
He-Ling Wen, Zhong-Shu Liang, Rui Zhang, Kan Yang
- Open Access
- Original investigation
Type 1 diabetes mellitus abrogates compensatory augmentation of myocardial neuregulin-1β/ErbB in response to myocardial infarction resulting in worsening heart failure
Oghenerukevwe Odiete, Ewa A Konik, Douglas B Sawyer, Michael F Hill
- Open Access
- Original investigation
Preserved endothelium-dependent dilatation of the coronary microvasculature at the early phase of diabetes mellitus despite the increased oxidative stress and depressed cardiac mechanical function ex vivo
Evangelia Mourmoura, Guillaume Vial, Brigitte Laillet, Jean-Paul Rigaudière, Isabelle Hininger-Favier, Hervé Dubouchaud, Beatrice Morio, Luc Demaison
- Open Access
- Original investigation
Role of ROCK upregulation in endothelial and smooth muscle vascular functions in diabetic rat aorta
Figen Amber Cicek, Hilmi B Kandilci, Belma Turan
- Open Access
- Original investigation
Zinc protects against diabetes-induced pathogenic changes in the aorta: roles of metallothionein and nuclear factor (erythroid-derived 2)-like 2
Xiao Miao, Yonggang Wang, Jian Sun, Weixia Sun, Yi Tan, Lu Cai, Yang Zheng, Guanfang Su, Quan Liu, Yuehui Wang
- Open Access
- Original investigation
Treatment of patients with type 2 diabetes with exenatide once weekly versus oral glucose-lowering medications or insulin glargine: achievement of glycemic and cardiovascular goals
Alison R Meloni, Mary Beth DeYoung, Jenny Han, Jennie H Best, Michael Grimm
- Open Access
- Original investigation
Serum pigment epithelium-derived factor levels are independently correlated with the presence of coronary artery disease
Feifei Wang, Xiaojing Ma, Mi Zhou, Xiaoping Pan, Jie Ni, Meifang Gao, Zhigang Lu, Jingyu Hang, Yuqian Bao, Weiping Jia
- Open Access
- Original investigation
Efficacy and safety of linagliptin in type 2 diabetes subjects at high risk for renal and cardiovascular disease: a pooled analysis of six phase III clinical trials
Maximilian von Eynatten, Yan Gong, Angela Emser, Hans-Juergen Woerle
- Open Access
- Original investigation
Metabolic disturbances and worsening of atherosclerotic lesions in ApoE-/- mice after cola beverages drinking
Matilde E Otero-Losada, Santiago Mc Loughlin, Gastón Rodríguez-Granillo, Angélica Müller, Graciela Ottaviano, Marisa Moriondo, Juan C Cutrin, José Milei
- Open Access
- Original investigation
Diabetes abrogates sex differences and aggravates cardiometabolic risk in postmenopausal women
Filipa Mascarenhas-Melo, Daniela Marado, Filipe Palavra, José Sereno, Álvaro Coelho, Rui Pinto, Edite Teixeira-Lemos, Frederico Teixeira, Flávio Reis
- Open Access
- Original investigation
Structured health care for subjects with diabetic foot ulcers results in a reduction of major amputation rates
Matthias Weck, Torsten Slesaczeck, Hartmut Paetzold, Dirk Muench, Thomas Nanning, Georg von Gagern, Andrej Brechow, Ulf Dietrich, Mandy Holfert, Stefan Bornstein, Andreas Barthel, Antje Thomas, Carsta Koehler, Markolf Hanefeld
- Open Access
- Original investigation
Glomerular filtration rate and albuminuria predict mortality independently from coronary artery calcified plaque in the Diabetes Heart Study
Amanda J Cox, Fang-Chi Hsu, J Jeffrey Carr, Barry I Freedman, Donald W Bowden
- Open Access
- Original investigation
Heparanase induced by advanced glycation end products (AGEs) promotes macrophage migration involving RAGE and PI3K/AKT pathway
Qiaojing Qin, Jianying Niu, Zhaoxia Wang, Wangjie Xu, Zhongdong Qiao, Yong Gu
- Open Access
- Original investigation
Sitagliptin pretreatment in diabetes patients presenting with acute coronary syndrome: results from the Acute Coronary Syndrome Israeli Survey (ACSIS)
Eyal Leibovitz, Shmuel Gottlieb, Ilan Goldenberg, Natalie Gevrielov-Yusim, Shlomi Matetzky, Dov Gavish
- Open Access
- Original investigation
Sagittal abdominal diameter is a more independent measure compared with waist circumference to predict arterial stiffness in subjects with type 2 diabetes - a prospective observational cohort study
Elsa M Dahlén, Niclas Bjarnegård, Toste Länne, Fredrik H Nystrom, Carl J Östgren
- Open Access
- Original investigation
Vildagliptin in addition to metformin improves retinal blood flow and erythrocyte deformability in patients with type 2 diabetes mellitus – results from an exploratory study
Christine Berndt-Zipfel, Georg Michelson, Markus Dworak, Michael Mitry, Andrea Löffler, Andreas Pfützner, Thomas Forst
- Open Access
- Original investigation
Early impairment of contractility reserve in patients with insulin resistance in comparison with healthy subjects
Christian Cadeddu, Silvio Nocco, Davide Piano, Martino Deidda, Efisio Cossu, Marco Giorgio Baroni, Giuseppe Mercuro
- Open Access
- Original investigation
The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats
Jianxin Lu, Jingzhang Ji, Howard Meng, David Wang, Bo Jiang, Lixin Liu, Edward Randell, Khosrow Adeli, Qing H Meng
- Open Access
- Original investigation
Asymmetric dimethylarginine predicts decline of glucose tolerance in men with stable coronary artery disease: a 4.5-year follow-up study
Andrzej Surdacki, Olga Kruszelnicka, Tomasz Rakowski, Aleksandra Jaźwińska-Kozuba, Jacek S Dubiel
- Open Access
- Original investigation
TRPV1-mediated UCP2 upregulation ameliorates hyperglycemia-induced endothelial dysfunction
Jing Sun, Yunfei Pu, Peijian Wang, Sijiao Chen, Yu Zhao, Chan Liu, Qianhui Shang, Zhiming Zhu, Daoyan Liu
- Open Access
- Original investigation
Common variants in adiponectin gene are associated with coronary artery disease and angiographical severity of coronary atherosclerosis in type 2 diabetes
Guoxin Tong, Ningfu Wang, Jianhang Leng, Xiaoshan Tong, Yun Shen, Jianmin Yang, Xianhua Ye, Liang Zhou, Yujie Zhou
- Open Access
- Original investigation
The sodium glucose cotransporter 2 inhibitor empagliflozin does not prolong QT interval in a thorough QT (TQT) study
Arne Ring, Tobias Brand, Sreeraj Macha, Kerstin Breithaupt-Groegler, Gudrun Simons, Beate Walter, Hans J Woerle, Uli C Broedl
- Open Access
- Original investigation
Impact of post-challenge hyperglycemia on clinical outcomes in japanese patients with stable angina undergoing percutaneous coronary intervention
Shoichi Kuramitsu, Hiroyoshi Yokoi, Takenori Domei, Akihiro Nomura, Hirotoshi Watanabe, Kyohei Yamaji, Yoshimitsu Soga, Takeshi Arita, Katsuhiro Kondo, Shinichi Shirai, Kenji Ando, Koyu Sakai, Masashi Iwabuchi, Hedeyuki Nosaka, Masakiyo Nobuyoshi
- Open Access
- Original investigation
Parallel evolution of circulating FABP4 and NT-proBNP in heart failure patients
Anna Cabré, Pilar Valdovinos, Iolanda Lázaro, Gil Bonet, Alfredo Bardají, Lluís Masana
- Open Access
- Original investigation
Effects of 24-week treatment with acarbose on glucagon-like peptide 1 in newly diagnosed type 2 diabetic patients: a preliminary report
Miao-yan Zheng, Ju-hong Yang, Chun-yan Shan, Hong-tao Zhou, Yan-guang Xu, Ying Wang, Hui-zhu Ren, Bao-cheng Chang, Li-ming Chen
- Open Access
- Original investigation
Role of Kir6.2 subunits of ATP-sensitive potassium channels in endotoxemia-induced cardiac dysfunction
Zhong-Wei Yang, Ji-Kuai Chen, Min Ni, Ting Zhao, Ya-Ping Deng, Xia Tao, Guo-Jun Jiang, Fu-Ming Shen
- Open Access
- Original investigation
Neck circumference as an independent predictive contributor to cardio-metabolic syndrome
Jing-ya Zhou, Hui Ge, Ming-fan Zhu, Li-jun Wang, Li Chen, Yao-zong Tan, Yu-ming Chen, Hui-lian Zhu
- Open Access
- Original investigation
Effects of co-administration of candesartan with pioglitazone on inflammatory parameters in hypertensive patients with type 2 diabetes mellitus: a preliminary report
Hirofumi Suzuki, Masaya Sakamoto, Takeshi Hayashi, Hiroyuki Iuchi, Kennosuke Ohashi, Tsuyoshi Isaka, Noriko Sakamoto, Yosuke Kayama, Katsuyoshi Tojo, Michihiro Yoshimura, Kazunori Utsunomiya
- Open Access
- Review
The role of co-morbidity in the selection of antidiabetic pharmacotherapy in type-2 diabetes
Diethelm Tschöpe, Markolf Hanefeld, Juris J Meier, Anselm K Gitt, Martin Halle, Peter Bramlage, Petra-Maria Schumm-Draeger
- Open Access
- Original investigation
AT1-receptor-deficiency induced atheroprotection in diabetic mice is partially mediated via PPARγ
Vedat Tiyerili, Ulrich M Becher, Adem Aksoy, Dieter Lütjohann, Sven Wassmann, Georg Nickenig, Cornelius FH Mueller
- Open Access
- Original investigation
Sex-specific-differences in cardiometabolic risk in type 1 diabetes: a cross-sectional study
Alexandra Kautzky-Willer, Kathrin Stich, Juliane Hintersteiner, Alexander Kautzky, Majid Reza Kamyar, Johannes Saukel, Julienne Johnson, Rosa Lemmens-Gruber
- Open Access
- Commentary
Management of hyperglycemia in type 2 diabetes: evidence and uncertainty
Katherine Esposito, Sandro Gentile, Riccardo Candido, Alberto De Micheli, Marco Gallo, Gerardo Medea, Antonio Ceriello
- Open Access
- Original investigation
Extensive impact of saturated fatty acids on metabolic and cardiovascular profile in rats with diet-induced obesity: a canonical analysis
Silvio A Oliveira Junior, Carlos R Padovani, Sergio A Rodrigues, Nilza R Silva, Paula F Martinez, Dijon HS Campos, Marina P Okoshi, Katashi Okoshi, Maeli Dal-Pai, Antonio C Cicogna
- Open Access
- Original investigation
HbA1c versus oral glucose tolerance test as a method to diagnose diabetes mellitus in vascular surgery patients
Iren D Hjellestad, Marianne C Astor, Roy M Nilsen, Eirik Søfteland, Torbjørn Jonung
- Open Access
- Original investigation
Diabetes severity and the role of leisure time physical exercise on cardiovascular mortality: the Nord-Trøndelag Health study (HUNT), Norway
Børge Moe, Liv Berit Augestad, Tom IL Nilsen
- Open Access
- Original investigation
Association between non-alcoholic fatty pancreatic disease (nafpd) and the metabolic syndrome: case–control retrospective study
Wan-Chen Wu, Chih-Yuan Wang
- Open Access
- Review
Selective peroxisome proliferator-activated receptorα modulators (SPPARMα): The next generation of peroxisome proliferator-activated receptor α-agonists
Jean-Charles Fruchart
- Open Access
- Original investigation
High glucose induces upregulation of scavenger receptors and promotes maturation of dendritic cells
Hao Lu, Kang Yao, Dong Huang, Aijun Sun, Yunzeng Zou, Juying Qian, Junbo Ge
- Open Access
- Original investigation
New concept of myocardial longitudinal strain reserve assessed by a dipyridamole infusion using 2D-strain echocardiography: the impact of diabetes and age, and the prognostic value
Thomas Cognet, Paul-Louis Vervueren, Laurent Dercle, Delphine Bastié, Rainui Richaud, Matthieu Berry, Pauline Marchal, Matthieu Gautier, Audrey Fouilloux, Michel Galinier, Didier Carrié, Pierre Massabuau, Isabelle Berry, Olivier Lairez
- Open Access
- Original investigation
Remodelling of the intracardiac ganglia in diabetic Goto-Kakizaki rats: an anatomical study
Darius Batulevicius, Thomas Frese, Elmar Peschke, Dainius H Pauza, Vaida Batuleviciene
- Open Access
- Original investigation
Comparative effect of clopidogrel and aspirin versus aspirin alone on laboratory parameters: a retrospective, observational, cohort study
Yasuo Takahashi, Yayoi Nishida, Tomohiro Nakayama, Satoshi Asai
- Open Access
- Original investigation
Miglitol improves postprandial endothelial dysfunction in patients with acute coronary syndrome and new-onset postprandial hyperglycemia
Daisuke Kitano, Masaaki Chiku, Yuxin Li, Yasuo Okumura, Daisuke Fukamachi, Tadateru Takayama, Takafumi Hiro, Satoshi Saito, Atsushi Hirayama
- Open Access
- Original investigation
Metabolic syndrome and abdominal fat are associated with inflammation, but not with clinical outcomes, in peritoneal dialysis patients
Jenq-Wen Huang, Chung-Yi Yang, Hon-Yen Wu, Kao-Lang Liu, Chi-Ting Su, Cho-Kai Wu, Jen-Kuang Lee, Chih-Kang Chiang, Hui-Teng Cheng, Yu-Chung Lien, Kuan-Yu Hung
- Open Access
- Original investigation
Impact of HDL genetic risk scores on coronary artery calcified plaque and mortality in individuals with type 2 diabetes from the Diabetes Heart Study
Laura M Raffield, Amanda J Cox, Fang-Chi Hsu, Maggie C-Y Ng, Carl D Langefeld, J Jeffrey Carr, Barry I Freedman, Donald W Bowden
- Open Access
- Original investigation
Metabolic, hemodynamic and structural adjustments to low intensity exercise training in a metabolic syndrome model
Eduardo Morvan, Nathalia Edviges Alves Lima, Jacqueline Freire Machi, Cristiano Mostarda, Kátia De Angelis, Maria Cláudia Irigoyen, Rogério Brandão Wichi, Bruno Rodrigues, Laura Beatriz Mesiano Maifrino
- Open Access
- Original investigation
Vascular complications and changes in body mass index in Japanese type 2 diabetic patients with abdominal obesity
Hirofumi Nagao, Susumu Kashine, Hitoshi Nishizawa, Takuya Okada, Takekazu Kimura, Ayumu Hirata, Shiro Fukuda, Junji Kozawa, Norikazu Maeda, Tetsuhiro Kitamura, Tetsuyuki Yasuda, Kohei Okita, Toshiyuki Hibuse, Mamiko Tsugawa, Akihisa Imagawa, Tohru Funahashi, Iichiro Shimomura
- Open Access
- Original investigation
Intermedin protects against myocardial ischemia-reperfusion injury in diabetic rats
Hong Li, Yunfei Bian, Nana Zhang, Jia Guo, Cheng Wang, Wayne Bond Lau, Chuanshi Xiao
- Open Access
- Original investigation
Association of arterial stiffness with single nucleotide polymorphism rs1333049 and metabolic risk factors
Suphawadee Phababpha, Upa Kukongviriyapan, Poungrat Pakdeechote, Laddawan Senggunprai, Veerapol Kukongviriyapan, Chatri Settasatian, Pyatat Tatsanavivat, Phongsak Intharaphet, Vichai Senthong, Nantarat Komanasin, Nongnuch Settasatian, Stephen E Greenwald
- Open Access
- Original investigation
Vitamin C further improves the protective effect of GLP-1 on the ischemia-reperfusion-like effect induced by hyperglycemia post-hypoglycemia in type 1 diabetes
Antonio Ceriello, Anna Novials, Emilio Ortega, Silvia Canivell, Gemma Pujadas, Lucia La Sala, Loredana Bucciarelli, Maurizio Rondinelli, Stefano Genovese
- Open Access
- Original investigation
Association of subclinical myocardial injury with arterial stiffness in patients with type 2 diabetes mellitus
Kai-Hang Yiu, Chun-Ting Zhao, Yan Chen, Chung-Wah Siu, Yap-Hang Chan, Kui-Kai Lau, Shasha Liu, Chu-Pak Lau, Hung-Fat Tse
- Open Access
- Original investigation
Caffeic acid phenethyl amide improves glucose homeostasis and attenuates the progression of vascular dysfunction in Streptozotocin-induced diabetic rats
Yi-Jin Ho, Wen-Pin Chen, Tzong-Cherng Chi, Ching-Chia Chang Chien, An-Sheng Lee, Hsi-Lin Chiu, Yueh-Hsiung Kuo, Ming-Jai Su
- Open Access
- Original investigation
Stiffness memory of EA.hy926 endothelial cells in response to chronic hyperglycemia
Marta Targosz-Korecka, Grzegorz D Brzezinka, Katarzyna E Malek, Ewa Stȩpień, Marek Szymonski
- Open Access
- Original investigation
Exercise and diabetes have opposite effects on the assembly and O-GlcNAc modification of the mSin3A/HDAC1/2 complex in the heart
Emily J Cox, Susan A Marsh
- Open Access
- Original investigation
Effects of FTO RS9939906 and MC4R RS17782313 on obesity, type 2 diabetes mellitus and blood pressure in patients with hypertension
Aline Marcadenti, Flavio D Fuchs, Ursula Matte, Fernanda Sperb, Leila B Moreira, Sandra C Fuchs
- Open Access
- Original investigation
Plaque vulnerability of coronary artery lesions is related to left ventricular dilatation as determined by optical coherence tomography and cardiac magnetic resonance imaging in patients with type 2 diabetes
Mathias Burgmaier, Michael Frick, Ana Liberman, Simone Battermann, Martin Hellmich, Walter Lehmacher, Agnes Jaskolka, Nikolaus Marx, Sebastian Reith
- Open Access
- Original investigation
Effects of icosapent ethyl on lipid and inflammatory parameters in patients with diabetes mellitus-2, residual elevated triglycerides (200–500 mg/dL), and on statin therapy at LDL-C goal: the ANCHOR study
Eliot A Brinton, Christie M Ballantyne, Harold E Bays, John J Kastelein, Rene A Braeckman, Paresh N Soni
- Open Access
- Original investigation
Insulin resistance is significantly associated with the metabolic syndrome, but not with sonographically proven peripheral arterial disease
Alexander Vonbank, Christoph H Saely, Philipp Rein, Heinz Drexel
- Open Access
- Original investigation
Inverse associations between light-to-moderate alcohol intake and lipid-related indices in patients with diabetes
Tomoko Shimomura, Ichiro Wakabayashi
- Open Access
- Original investigation
Low-grade albuminuria is associated with early but not late carotid atherosclerotic lesions in community-based patients with type 2 diabetes
Mei-Fang Li, Yin-Fang Tu, Lian-Xi Li, Jun-Xi Lu, Xue-Hong Dong, Li-Bo Yu, Rong Zhang, Yu-Qian Bao, Wei-Ping Jia, Ren-Ming Hu
- Open Access
- Original investigation
Genetic variants predicting left ventricular hypertrophy in a diabetic population: a Go-DARTS study including meta-analysis
Helen M Parry, Louise A Donnelly, Natalie Van Zuydam, Alexander SF Doney, Douglas HJ Elder, Andrew D Morris, Alan D Struthers, Colin NA Palmer, Chim C Lang
- Open Access
- Original investigation
Association between serum adipocyte fatty-acid binding protein concentrations, left ventricular function and myocardial perfusion abnormalities in patients with coronary artery disease
Chi-Lun Huang, Yen-Wen Wu, Chih-Cheng Wu, Lin Lin, Yu-Chin Wu, Pei-Ying Hsu, Yuh-Shiun Jong, Wei-Shiung Yang
- Open Access
- Original investigation
Acute Rho-kinase inhibition improves coronary dysfunction in vivo, in the early diabetic microcirculation
James T Pearson, Mathew J Jenkins, Amanda J Edgley, Takashi Sonobe, Mandar Joshi, Mark T Waddingham, Yutaka Fujii, Daryl O Schwenke, Hirotsugu Tsuchimochi, Misa Yoshimoto, Keiji Umetani, Darren J Kelly, Mikiyasu Shirai
- Open Access
- Original investigation
Hemoglobin A1c variability as an independent correlate of cardiovascular disease in patients with type 2 diabetes: a cross-sectional analysis of the Renal Insufficiency and Cardiovascular Events (RIACE) Italian Multicenter Study
Giuseppe Penno, Anna Solini, Giacomo Zoppini, Emanuela Orsi, Cecilia Fondelli, Gianpaolo Zerbini, Susanna Morano, Franco Cavalot, Olga Lamacchia, Roberto Trevisan, Monica Vedovato, Giuseppe Pugliese
- Open Access
- Original investigation
Impaired skin microcirculation in paediatric patients with type 1 diabetes mellitus
Mirjam Heimhalt-El Hamriti, Corinna Schreiver, Anja Noerenberg, Julia Scheffler, Ulrike Jacoby, Dieter Haffner, Dagmar-C Fischer
- Open Access
- Original investigation
Plasma levels of the arterial wall protein fibulin-1 are associated with carotid-femoral pulse wave velocity: a cross-sectional study
Esben Laugesen, Pernille Høyem, Jens Sandahl Christiansen, Søren Tang Knudsen, Klavs Würgler Hansen, W Scott Argraves, Troels Krarup Hansen, Per Løgstrup Poulsen, Lars Melholt Rasmussen
- Open Access
- Original investigation
Vitamin D supplementation in patients with diabetes mellitus type 2 on different therapeutic regimens: a one-year prospective study
Khalid M Alkharfy, Nasser M Al-Daghri, Shaun B Sabico, Abdulaziz Al-Othman, Osama Moharram, Majed S Alokail, Yousef Al-Saleh, Sudhesh Kumar, George P Chrousos
- Open Access
- Original investigation
The neurogenic response of cardiac resident nestin(+) cells was associated with GAP43 upregulation and abrogated in a setting of type I diabetes
Andreanne Chabot, Marc-Andre Meus, Vanessa Hertig, Natacha Duquette, Angelino Calderone
- Open Access
- Original investigation
Association of circulating levels of nicotinamide phosphoribosyltransferase (NAMPT/Visfatin) and of a frequent polymorphism in the promoter of the NAMPT gene with coronary artery disease in diabetic and non-diabetic subjects
Pedro Saddi-Rosa, Carolina Soares Oliveira, Felipe Crispim, Fernando MA Giuffrida, Valter Correia de Lima, José Gilberto Vieira, Alessandro Doria, Gilberto Velho, André Fernandes Reis
- Open Access
- Original investigation
Circulating alpha-klotho levels are not disturbed in patients with type 2 diabetes with and without macrovascular disease in the absence of nephropathy
Joris van Ark, Hans-Peter Hammes, Marcory C R F van Dijk, Marc G Vervloet, Bruce H R Wolffenbuttel, Harry van Goor, Jan-Luuk Hillebrands
- Open Access
- Original investigation
Circulating concentrations of GLP-1 are associated with coronary atherosclerosis in humans
Katja Piotrowski, Melanie Becker, Julia Zugwurst, Ingeborg Biller-Friedmann, Gerald Spoettl, Martin Greif, Alexander W Leber, Alexander Becker, Rüdiger P Laubender, Corinna Lebherz, Burkhard Goeke, Nikolaus Marx, Klaus G Parhofer, Michael Lehrke
- Open Access
- Original investigation
Prognostic value of coronary flow reserve assessed by transthoracic Doppler echocardiography on long-term outcome in asymptomatic patients with type 2 diabetes without overt coronary artery disease
Takayuki Kawata, Masao Daimon, Rei Hasegawa, Tomohiko Toyoda, Tai Sekine, Toshiharu Himi, Daigaku Uchida, Sakiko Miyazaki, Kuniaki Hirose, Ryoko Ichikawa, Masaki Maruyama, Hiromasa Suzuki, Hiroyuki Daida
- Open Access
- Original investigation
24-hour central aortic systolic pressure and 24-hour central pulse pressure are related to diabetic complications in type 1 diabetes – a cross-sectional study
Simone Theilade, Maria Lajer, Tine Willum Hansen, Christel Joergensen, Frederik Persson, Gudbjörg Andrésdottir, Henrik Reinhard, Stine Elkjær Nielsen, Peter Lacy, Bryan Williams, Peter Rossing
- Open Access
- Original investigation
Advanced glycation end products evoke endothelial cell damage by stimulating soluble dipeptidyl peptidase-4 production and its interaction with mannose 6-phosphate/insulin-like growth factor II receptor
Yuji Ishibashi, Takanori Matsui, Sayaka Maeda, Yuichiro Higashimoto, Sho-ichi Yamagishi
- Open Access
- Study protocol
Efficacy and safety of combination therapy with vildagliptin and metformin versus metformin up-titration in Chinese patients with type 2 diabetes mellitus: study design and rationale of the vision study
Li-Nong Ji, Chang-Yu Pan, Ju-Ming Lu, Hong Li, Qiang Li, Qi-Fu Li, Yong-De Peng, Hao-Ming Tian, Chen Yao, Zhi-Gang Zhao, Ru-Ya Zhang, Xiang-Ling Wang, Lei Wang
- Open Access
- Original investigation
Additive relationship between serum fibroblast growth factor 21 level and coronary artery disease
Yun Shen, Xiaojing Ma, Jian Zhou, Xiaoping Pan, Yaping Hao, Mi Zhou, Zhigang Lu, Meifang Gao, Yuqian Bao, Weiping Jia
- Open Access
- Original investigation
Interleukin-6 and activin A are independently associated with cardiovascular events and mortality in type 2 diabetes: the prospective Asker and Bærum Cardiovascular Diabetes (ABCD) cohort study
Anne Pernille Ofstad, Lars Gullestad, Elsa Orvik, Svend Aakhus, Knut Endresen, Thor Ueland, Pål Aukrust, Morten W Fagerland, Kåre I Birkeland, Odd Erik Johansen
- Open Access
- Original investigation
Accumulation of epicardial fat rather than visceral fat is an independent risk factor for left ventricular diastolic dysfunction in patients undergoing peritoneal dialysis
Heng-Hsu Lin, Jen-Kuang Lee, Chung-Yi Yang, Yu-Chung Lien, Jenq-Wen Huang, Cho-Kai Wu
- Open Access
- Review
The cardiovascular safety of incretin-based therapies: a review of the evidence
John R Petrie
- Open Access
- Original investigation
Baseline and 1-year interim follow-up assessment of Japanese patients initiating insulin therapy who were enrolled in the cardiovascular risk evaluation in people with type 2 diabetes on insulin therapy study: an international, multicenter, observational study
Ryuzo Kawamori, Koichi Node, Toshiaki Hanafusa, Yoshihito Atsumi, Yusuke Naito, Yoshitomo Oka
- Open Access
- Original investigation
Blood lead is significantly associated with metabolic syndrome in Korean adults: an analysis based on the Korea National Health and Nutrition Examination Survey (KNHANES), 2008
Sang Youl Rhee, You-Cheol Hwang, Jeong-taek Woo, Dong Hyun Sinn, Sang Ouk Chin, Suk Chon, Young Seol Young Seol Kim
- Open Access
- Study protocol
Rationale, design and baseline characteristics of a 4-year (208-week) phase III trial of empagliflozin, an SGLT2 inhibitor, versus glimepiride as add-on to metformin in patients with type 2 diabetes mellitus with insufficient glycemic control
Martin Ridderstråle, Robbyna Svaerd, Cordula Zeller, Gabriel Kim, Hans J Woerle, Uli C Broedl
- Open Access
- Original investigation
Association between aldehyde dehydrogenase 2 polymorphisms and the incidence of diabetic retinopathy among Japanese subjects with type 2 diabetes mellitus
Kazunori Morita, Junji Saruwatari, Haruna Miyagawa, Yoshihiro Uchiyashiki, Kentaro Oniki, Misaki Sakata, Ayami Kajiwara, Akira Yoshida, Hideaki Jinnouchi, Kazuko Nakagawa
- Open Access
- Original investigation
Susceptibility to myocardial ischemia reperfusion injury at early stage of type 1 diabetes in rats
Haobo Li, Zipeng Liu, Junwen Wang, Gordon T Wong, Chi-Wai Cheung, Liangqing Zhang, Can Chen, Zhengyuan Xia, Michael G Irwin
- Open Access
- Original investigation
Impact of the LDL subfraction phenotype on Lp-PLA2 distribution, LDL modification and HDL composition in type 2 diabetes
Jose Luis Sánchez-Quesada, Irene Vinagre, Elena De Juan-Franco, Juan Sánchez-Hernández, Rosa Bonet-Marques, Francisco Blanco-Vaca, Jordi Ordóñez-Llanos, Antonio Pérez
- Open Access
- Erratum
Erratum to: Circulating alpha-klotho levels are not disturbed in patients with type 2 diabetes with and without macrovascular disease in the absence of nephropathy
Joris van Ark, Hans-Peter Hammes, Marcory CRF van Dijk, Chris PH Lexis, Iwan CC van der Horst, Clark J Zeebregts, Marc G Vervloet, Bruce HR Wolffenbuttel, Harry van Goor, Jan-Luuk Hillebrands
- Open Access
- Original investigation
Protection of the heart by treatment with a divalent-copper-selective chelator reveals a novel mechanism underlying cardiomyopathy in diabetic rats
Lin Zhang, Marie-Louise Ward, Anthony RJ Phillips, Shaoping Zhang, John Kennedy, Bernard Barry, Mark B Cannell, Garth JS Cooper
- Open Access
- Original investigation
Mesenchymal stem cell transplantation for the infarcted heart: therapeutic potential for insulin resistance beyond the heart
Curtis C Hughey, Lianli Ma, Freyja D James, Deanna P Bracy, Zhizhang Wang, David H Wasserman, Jeffrey N Rottman, Dustin S Hittel, Jane Shearer
- Open Access
- Original investigation
Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin
Latt S Mansor, Eileen R Gonzalez, Mark A Cole, Damian J Tyler, Jessica H Beeson, Kieran Clarke, Carolyn A Carr, Lisa C Heather
- Open Access
- Review
Cardiac implications of hypoglycaemia in patients with diabetes – a systematic review
Markolf Hanefeld, Eva Duetting, Peter Bramlage
- Open Access
- Original investigation
Urinary adiponectin concentration is positively associated with micro- and macro-vascular complications
Won Seon Jeon, Ji Woo Park, Namseok Lee, Se Eun Park, Eun Jung Rhee, Won Young Lee, Ki Won Oh, Sung Woo Park, Cheol-Young Park, Byung-Soo Youn
- Open Access
- Original investigation
Lipoprotein(a) is not related to markers of insulin resistance in pregnancy
Jelena Todoric, Ammon Handisurya, Karoline Leitner, Juergen Harreiter, Gregor Hoermann, Alexandra Kautzky-Willer
- Open Access
- Original investigation
Usefulness of metabolic syndrome score in the prediction of angiographic coronary artery disease severity according to the presence of diabetes mellitus: relation with inflammatory markers and adipokines
Jong-Youn Kim, Eui-Young Choi, Hee-Sun Mun, Pil-Ki Min, Young-Won Yoon, Byoung Kwon Lee, Bum-Kee Hong, Se-Joong Rim, Hyuck Moon Kwon
- Open Access
- Study protocol
Rationale and design of a randomized trial on the impact of aldosterone antagonism on cardiac structure and function in diabetic cardiomyopathy
Melissa Leung, Vincent W Wong, Stephane Heritier, Anastasia S Mihailidou, Dominic Y Leung
- Open Access
- Original investigation
Hyperglycemia induces differential change in oxidative stress at gene expression and functional levels in HUVEC and HMVEC
Hemang Patel, Juan Chen, Kumuda C Das, Mahendra Kavdia
- Open Access
- Original investigation
Differential associations of angiographic extent and severity of coronary artery disease with asymmetric dimethylarginine but not insulin resistance in non-diabetic men with stable angina: a cross-sectional study
Olga Kruszelnicka, Andrzej Surdacki, Alain Golay
- Open Access
- Original investigation
The activity of circulating dipeptidyl peptidase-4 is associated with subclinical left ventricular dysfunction in patients with type 2 diabetes mellitus
Susana Ravassa, Joaquín Barba, Isabel Coma-Canella, Ana Huerta, Begoña López, Arantxa González, Javier Díez
- Open Access
- Original investigation
Serum electrolyte levels in relation to macrovascular complications in Chinese patients with diabetes mellitus
Shenqi Wang, Xuhong Hou, Yu Liu, Huijuan Lu, Li Wei, Yuqian Bao, Weiping Jia
- Open Access
- Original investigation
Interferon regulatory factor-1 together with reactive oxygen species promotes the acceleration of cell cycle progression by up-regulating the cyclin E and CDK2 genes during high glucose-induced proliferation of vascular smooth muscle cells
Xi Zhang, Long Liu, Chao Chen, Ya-Li Chi, Xiang-Qun Yang, Yan Xu, Xiao-Tong Li, Shi-Lei Guo, Shao-Hu Xiong, Man-Ru Shen, Yu Sun, Chuan-Sen Zhang, Kai-Meng Hu
- Open Access
- Original investigation
Novel fusion of GLP-1 with a domain antibody to serum albumin prolongs protection against myocardial ischemia/reperfusion injury in the rat
Weike Bao, Lucy J Holt, Rob D Prince, Gavin X Jones, Karpagam Aravindhan, Mathew Szapacs, April M Barbour, Larry J Jolivette, John J Lepore, Robert N Willette, Elena DeAngelis, Beat M Jucker
- Open Access
- Original investigation
Activin a is associated with impaired myocardial glucose metabolism and left ventricular remodeling in patients with uncomplicated type 2 diabetes
Weena JY Chen, Sabrina Greulich, Rutger W van der Meer, Luuk J Rijzewijk, Hildo J Lamb, Albert de Roos, Johannes WA Smit, Johannes A Romijn, Johannes B Ruige, Adriaan A Lammertsma, Mark Lubberink, Michaela Diamant, D Margriet Ouwens
- Open Access
- Original investigation
Preclinical atherosclerosis and metabolic syndrome increase cardio- and cerebrovascular events rate: a 20-year follow up
Salvatore Novo, Angelica Peritore, Rosaria Linda Trovato, Francesco Paolo Guarneri, Daniela Di Lisi, Ida Muratori, Giuseppina Novo
- Open Access
- Erratum
Erratum to: The metabolic syndrome and progression of carotid atherosclerosis over 13 years: the Tromsø study
Marit Herder, Kjell Arne Arntzen, Stein Harald Johnsen, Ellisiv B Mathiesen
- Open Access
- Original investigation
Dipeptidyl peptidase-4 inhibitors and GLP-1 reduce myocardial infarct size in a glucose-dependent manner
Derek J Hausenloy, Hannah J Whittington, Abigail M Wynne, Shah S Begum, Louise Theodorou, Niels Riksen, Mihaela M Mocanu, Derek M Yellon
- Open Access
- Review
Type 1 diabetes and cardiovascular disease
Oliver Schnell, Francesco Cappuccio, Stefano Genovese, Eberhard Standl, Paul Valensi, Antonio Ceriello
- Open Access
- Original investigation
The role of profilin-1 in endothelial cell injury induced by advanced glycation end products (AGEs)
Zhenyu Li, Qiaoqing Zhong, Tianlun Yang, Xiumei Xie, Meifang Chen
- Open Access
- Original investigation
Arg972 Insulin receptor substrate-1 is associated with decreased serum angiotensin-converting enzyme 2 levels in acute myocardial infarction patients: in vivo and in vitro evidence
Wei Liu, Xinmin Zhou, Fenglei Yu, Jianguo Hu, Wen Hu
- Open Access
- Original investigation
High sensitive C-reactive protein and serum amyloid A are inversely related to serum bilirubin: effect-modification by metabolic syndrome
Petronella E Deetman, Stephan JL Bakker, Robin PF Dullaart
- Open Access
- Original investigation
Haemoglobin A1c even within non-diabetic level is a predictor of cardiovascular disease in a general Japanese population: the Hisayama Study
Fumie Ikeda, Yasufumi Doi, Toshiharu Ninomiya, Yoichiro Hirakawa, Naoko Mukai, Jun Hata, Kentaro Shikata, Daigo Yoshida, Takayuki Matsumoto, Takanari Kitazono, Yutaka Kiyohara
- Open Access
- Original investigation
Long-term prognostic impact of cystatin c on acute coronary syndrome octogenarians with diabetes mellitus
Zhenhong Fu, Hao Xue, Jun Guo, Lian Chen, Wei Dong, Luyue Gai, Hongbin Liu, Zhijun Sun, Yundai Chen
- Open Access
- Original investigation
Protein kinase RNA- like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)- mediated endoplasmic reticulum stress- induced apoptosis in diabetic cardiomyopathy
Zhong-Wei Liu, Hai-Tao Zhu, Kun-Lun Chen, Xin Dong, Jin Wei, Chuan Qiu, Jia-Hong Xue
- Open Access
- Original investigation
Comparative effect of angiotensin II type I receptor blockers on serum uric acid in hypertensive patients with type 2 diabetes mellitus: a retrospective observational study
Yayoi Nishida, Yasuo Takahashi, Norio Susa, Nobukazu Kanou, Tomohiro Nakayama, Satoshi Asai
- Open Access
- Original investigation
Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes
Katsutoshi Miyagawa, Tatsuya Kondo, Rieko Goto, Rina Matsuyama, Kaoru Ono, Sayaka Kitano, Shuji Kawasaki, Motoyuki Igata, Junji Kawashima, Takeshi Matsumura, Hiroyuki Motoshima, Eiichi Araki
- Open Access
- Original investigation
Coronary calcium in patients with and without diabetes: first manifestation of acute or chronic coronary events is characterized by different calcification patterns
Joseph Shemesh, Alexander Tenenbaum, Enrique Z Fisman, Nira Koren-Morag, Ehud Grossman
- Open Access
- Original investigation
Arterial stiffness, fatty liver and the presence of coronary artery calcium in a large population cohort
Ki-Chul Sung, Young-Hyo Lim, Sungha Park, Seok-Min Kang, Jeong Bae Park, Byung-Jin Kim, Jin-Ho Shin
- Open Access
- Original investigation
Plasma copeptin levels are inversely associated with intima-media-thickness in men: the population-based KORA F4 study
Cornelia Then, Bernd Kowall, Andreas Lechner, Christa Meisinger, Margit Heier, Wolfgang Koenig, Annette Peters, Joachim Thiery, Wolfgang Rathmann, Jochen Seissler
- Open Access
- Original investigation
Obesity and high waist circumference are associated with low circulating pentraxin-3 in acute coronary syndrome
Rocco Barazzoni, Aneta Aleksova, Cosimo Carriere, Maria Rosa Cattin, Michela Zanetti, Pierandrea Vinci, Davide Stolfo, Gianfranco Guarnieri, Gianfranco Sinagra
- Open Access
- Original investigation
Angiotensin type 1a receptor-deficient mice develop diabetes-induced cardiac dysfunction, which is prevented by renin-angiotensin system inhibitors
Qian Chen Yong, Candice M Thomas, Rachid Seqqat, Niketa Chandel, Kenneth M Baker, Rajesh Kumar
- Open Access
- Original investigation
High admission glucose levels increase Fas apoptosis and mortality in patients with acute ST-elevation myocardial infarction: a prospective cohort study
Jing Chang, Gong Zhang, Li Zhang, Yuan-Ping Hou, Xiu-Lan Liu, Lin Zhang
- Open Access
- Original investigation
Metabolism of plasma cholesterol and lipoprotein parameters are related to a higher degree of insulin sensitivity in high HDL-C healthy normal weight subjects
Camila C Leança, Valéria S Nunes, Natália B Panzoldo, Vanessa S Zago, Eliane S Parra, Patrícia M Cazita, Matti Jauhiainen, Marisa Passarelli, Edna R Nakandakare, Eliana C de Faria, Eder CR Quintão
- Open Access
- Original investigation
Total and high molecular weight adiponectin and ethnic-specific differences in adiposity and insulin resistance: a cross-sectional study
Dian C Sulistyoningrum, Danijela Gasevic, Scott A Lear, Joe Ho, Andrew Mente, Angela M Devlin
- Open Access
- Original investigation
Do patients with type 1 and type 2 diabetes really have an impaired endothelial function? A population-based propensity score matching analysis
Klaus Empen, Roberto Lorbeer, Henry Völzke, Thorsten Reffelmann, Sabine Schipf, Matthias Nauck, Wolfgang Kerner, Henri Wallaschofski, Stephan B Felix, Marcus Dörr
- Open Access
- Original investigation
Eplerenone attenuated cardiac steatosis, apoptosis and diastolic dysfunction in experimental type-II diabetes
Elisa Ramírez, Mercedes Klett-Mingo, Sara Ares-Carrasco, Belén Picatoste, Alessia Ferrarini, Francisco J Rupérez, Alicia Caro-Vadillo, Coral Barbas, Jesús Egido, José Tuñón, Óscar Lorenzo
- Open Access
- Original investigation
Effects of two weeks of metformin treatment on whole-body glycocalyx barrier properties in db/db mice
Bart JM Eskens, Coert J Zuurbier, Judith van Haare, Hans Vink, Jurgen WGE van Teeffelen
- Open Access
- Original investigation
Serum lipocalin-2 levels positively correlate with coronary artery disease and metabolic syndrome
Jie Ni, Xiaojing Ma, Mi Zhou, Xiaoping Pan, Junling Tang, Yaping Hao, Zhigang Lu, Meifang Gao, Yuqian Bao, Weiping Jia
- Open Access
- Original investigation
Association between circulating leukocyte subtype counts and carotid intima-media thickness in Japanese subjects with type 2 diabetes
Takeshi Matsumura, Kayo Taketa, Hiroyuki Motoshima, Takafumi Senokuchi, Norio Ishii, Hiroyuki Kinoshita, Kazuki Fukuda, Sarie Yamada, Daisuke Kukidome, Tatsuya Kondo, Aya Hisada, Takahiko Katoh, Seiya Shimoda, Takeshi Nishikawa, Eiichi Araki
- Open Access
- Original investigation
Methylglyoxal modulates endothelial nitric oxide synthase-associated functions in EA.hy926 endothelial cells
Yang Su, Syed M Qadri, Lingyun Wu, Lixin Liu
- Open Access
- Original investigation
Plasma levels of advanced glycation endproducts are associated with type 1 diabetes and coronary artery calcification
Marcelle GA van Eupen, Miranda T Schram, Helen M Colhoun, Jean LJM Scheijen, Coen DA Stehouwer, Casper G Schalkwijk
- Open Access
- Original investigation
Diabetes mellitus activates fetal gene program and intensifies cardiac remodeling and oxidative stress in aged spontaneously hypertensive rats
Camila Moreno Rosa, Natasha Priscilla Xavier, Dijon Henrique Campos, Ana Angélica Henrique Fernandes, Marcelo Diarcadia Mariano Cezar, Paula Felippe Martinez, Antonio Carlos Cicogna, Camila Gimenes, Rodrigo Gimenes, Marina Politi Okoshi, Katashi Okoshi
- Open Access
- Original investigation
The relationship between early atherosclerosis and endothelial dysfunction in type 1 diabetic patients as evidenced by measurement of carotid intima-media thickness and soluble CD146 levels: a cross sectional study
Sema Ciftci Dogansen, Aysen Helvaci, Mine Adas, Suzan Deniz Onal
- Open Access
- Original investigation
Association of increased serum glycated albumin levels with low coronary collateralization in type 2 diabetic patients with stable angina and chronic total occlusion
Ying Shen, Lin Lu, Feng Hua Ding, Zhen Sun, Rui Yan Zhang, Qi Zhang, Zheng Kun Yang, Jian Hu, Qiu Jing Chen, Wei Feng Shen
- Open Access
- Original investigation
Safety and efficacy of long-term combination therapy with bezafibrate and ezetimibe in patients with dyslipidemia in the prospective, observational J-COMPATIBLE study
Tamio Teramoto, Kazunori Abe, Takehiko Taneyama