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The Impact of Cardio-Renal-Metabolic Profile in Dilated Cardiomyopathy

  • Open Access
  • 23-05-2025
  • Cardiomyopathy
  • Myocardial Disease (A Abbate and M Merlo, Section Editors)
Published in:

Abstract

Purpose of Review

Dilated cardiomyopathy is an important contributor to heart failure burden worldwide. With an aging population and rising multimorbidity, in this review, we describe the prevalence of metabolic syndrome and renal failure in patients with dilated cardiomyopathy and focus on common underlying mechanisms, evaluate outcomes in these patients and highlight newer therapeutic strategies.

Recent Findings

A significant proportion of patients with dilated cardiomyopathy has concomitant metabolic syndrome and renal disease. This combination of multimorbidity portends worse prognosis and often presents unique challenges in treatment given the complex interplay and shared pathophysiological pathways.

Summary

Optimization of the cardio-renal-metabolic profile should be a key consideration in the management of patients with dilated cardiomyopathy. Therapeutic strategies targeting common pathophysiological pathways are needed in order to improve overall outcomes.
Title
The Impact of Cardio-Renal-Metabolic Profile in Dilated Cardiomyopathy
Authors
Tamim Akbari
Daniel J. Hammersley
Clarice Yau-Yee May
Brian P. Halliday
Sanjay K. Prasad
Publication date
23-05-2025
Publisher
Springer US
Published in
Current Cardiology Reports / Issue 1/2025
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-025-02241-8
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