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Current Cardiology Reports

Chagas Disease: Epidemiology, Diagnosis, and Treatment

Published in:
Authors
Michael C. Swett
Danny L. Rayes
Silvia Vidal Campos
Rebecca N. Kumar
Published in
Current Cardiology Reports | Issue 10/2024

Abstract

Purpose of Review

This review seeks to describe the updates in the literature – particularly with regards to the epidemiology and diagnosis of Chagas disease. Additionally, this paper describes updates to the antiparasitic treatment for Chagas disease.

Recent Findings

With regards to changing epidemiology, autochthonous cases are being found within the USA in addition to Latin America. Additionally, there appears to be more intermixing of discrete typing units—meaning, they are not confined to specific geographic regions. Screening for Chagas disease is recommended in persons who lived in areas with endemic Chagas, persons wtih family member diagnosed with Chagas Disease, persons who have lived in homes of natural material in Latin America, and persons with history of kissing bug bites. Treatment for the parasitic infection remains limited to benznidazole and nifurtimox, and the role of these treatments in Chagas cardiomyopathy has not yet been definitively defined. Finally, indications for and management of heart transplant in the setting of Chagas disease are discussed.

Future Research

Use of antiparasitics during chronic chagas disease should be further explored. Additionally, future research identifying other markers of infection would be valuable to defining cure from infection.
Title
Chagas Disease: Epidemiology, Diagnosis, and Treatment
Authors
Michael C. Swett
Danny L. Rayes
Silvia Vidal Campos
Rebecca N. Kumar
Publication date
08-08-2024
Publisher
Springer US
Keyword
Cardiomyopathy
Published in
Current Cardiology Reports / Issue 10/2024
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-024-02113-7
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This content is intended for healthcare professionals outside of the UK.

Independent Medical Education Grant:
  • Bayer HealthCare Pharmaceuticals Inc.
Learn more Link opens in a new window
Image Credits
Abstract graphic of layered, concentric circular shapes in bright green, pink, blue, and purple on a dark blue background. The rings and segments form a complex radial pattern without text/© Springer Health+ IME