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27-10-2023 | Cancer of Unknown Primary | Expert Interview | Article | F. Hoffmann-La Roche Ltd.

Cancer of Unknown Primary: Key results from ESMO 2023


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CUPISCO trial approach extends progression-free survival for CUP patients

CUPISCO trial investigator Prof. Linda Mileshkin describes the progression-free survival benefit achieved with use of molecularly guided treatment versus standard chemotherapy for patients with cancer of unknown primary.

Presentation date: Saturday 21st October 2023


  • Prof. Linda Mileshkin
    Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

ARCAGEN matches targeted treatment to almost half of rare tumor types

Dr. Marie Morfouace and Prof. Jean-Yves Blay discuss initial ARCAGEN study findings showing that almost half of patients with cancers of unknown primary and other rare tumors can be matched to a molecularly targeted therapy.

Presentation date: Sunday 22nd October 2023


  • Dr. Marie Morfouace
    EORTC, Brussels, Belgium
  • Prof. Jean-Yves Blay
    Centre Léon Bérard, Lyon, France

CUP-ONE supports gene expression assay for cancer of unknown primary 

Watch Dr. Harpreet Wasan explain the benefits of a joint gene expression and immunohistochemistry approach to identifying cancer of unknown primary origin.

Presentation date: Sunday 22nd October 2023


  • Dr. Harpreet Wasan
    Imperial College London, UK

Gene expression-directed chemotherapy improves CUP patient survival

Phase 3 trial findings show that a 90-gene expression assay can aid choice of chemotherapy and improve survival for patients with cancer of unknown primary.

Presentation date: Sunday 22nd October 2023


  • Prof. Zhiguo Luo 
    Fudan University Shanghai Cancer Center, China

Financial disclosure

This content is intended only for healthcare providers and was made possible by educational funding provided by F. Hoffmann-La Roche Ltd.


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