Issue 11/2024
Content (26 Articles)
- Open Access
- Checkpoint Inhibitors
- Research
Outcome of immune checkpoint inhibitor treatment in non-small cell lung cancer patients with interstitial lung abnormalities: clinical utility of subcategorizing interstitial lung abnormalities
Ryota Kikuchi, Yusuke Watanabe, Takashi Okuma, Hiroyuki Nakamura, Shinji Abe
- Open Access
- Metastasis
- Research
Increasing monocytes after lung cancer surgery triggers the outgrowth of distant metastases, causing recurrence
Yo Kawaguchi, Keigo Okamoto, Yoko Kataoka, Kohei Shibata, Hiroki Saito, Takuya Shiratori, Keiko Ueda, Yasuhiko Ohshio, Jun Hanaoka
- Open Access
- Brief Report
High proportion of PD-1 and CD39 positive CD8+ tissue resident T lymphocytes correlates with better clinical outcome in resected human oesophageal adenocarcinoma
Samuel L. Hill, Gessa Sugiyarto, Jack Harrington, Edward James, Timothy J. Underwood, Tim Elliott
- Open Access
- Checkpoint Inhibitors
- Research
Characterization of pre- and on-treatment soluble immune mediators and the tumor microenvironment in NSCLC patients receiving PD-1/L1 inhibitor monotherapy
Daiki Murata, Koichi Azuma, Kenta Murotani, Akihiko Kawahara, Yuuya Nishii, Takaaki Tokito, Tetsuro Sasada, Tomoaki Hoshino
- Open Access
- Colorectal Cancer
- Research
Immune microenvironmental heterogeneity according to tumor DNA methylation phenotypes in microsatellite instability-high colorectal cancers
Jung Ho Kim, Jiyun Hong, Ji Ae Lee, Minsun Jung, Eunwoo Choi, Nam-Yun Cho, Gyeong Hoon Kang, Sangwoo Kim
- Open Access
- Gastrectomy
- Research
The short-term efficacy of neoadjuvant SOX versus SOX plus immune checkpoint inhibitor following laparoscopic gastrectomy for locally advanced gastric cancer: a multicenter retrospective cohort study in China
Hao Cui, Yongpu Yang, Liqiang Song, Zhen Yuan, Linde Sun, Jiajun Du, Yuyuan Lu, Ning Ning, Jianxin Cui, Yan Shi, Lin Chen, Bo Wei
- Open Access
- Lung Cancer
- Research
Immunogenomic features of radiologically distinctive nodules in multiple primary lung cancer
Mei-Cheng Chen, Hao-Shuai Yang, Zhi Dong, Lu-Jie Li, Xiang-Min Li, Hong-He Luo, Qiong Li, Ying Zhu
- Open Access
- Melanoma
- Brief Report
Stat3-mediated Atg7 expression regulates anti-tumor immunity in mouse melanoma
Sarah M. Zimmerman, Erin Suh, Sofia R. Smith, George P. Souroullas
- Open Access
- Hepatocellular Carcinoma
- Research
SAFFRON-104: a phase Ib/II study of sitravatinib alone or with tislelizumab in advanced hepatocellular carcinoma and gastric cancer/gastroesophageal junction cancer
Jin Li, Yuxian Bai, Zhendong Chen, Jieer Ying, Yabing Guo, Weijia Fang, Feng Zhang, Jianping Xiong, Tao Zhang, Zhiqiang Meng, Jingdong Zhang, Zhenggang Ren, Chunyi Hao, Yajin Chen, Xiaoyan Lin, Hongming Pan, Fuxiang Zhou, Xin Li, Fan Yu, Juan Zhang, Zhang Zhang, Shukui Qin
- Open Access
- Cytostatic Therapy
- Research
Efficacy of durvalumab plus chemotherapy in advanced biliary duct cancer and biomarkers exploration
Yunxin Lu, Yin Jin, Furong Liu, Zixian Wang, Wen Zhou, Yang Zhang, Bing Bai, Yun Wang, Zhiqiang Wang, Man Nie, Huiyan Luo, Xiaoli Wei, Chuqiao Liang, Guifang Guo, Miaozhen Qiu, Jianwen Chen, Yu Liu, Shengping Li, Yuhong Li, Fenghua Wang, Feng Wang, Peidong Chi, Dongsheng Zhang
- Open Access
- Neuroblastoma
- Research
Oncolytic virotherapy augments self-maintaining natural killer cell line cytotoxicity against neuroblastoma
Colin H. Quinn, Janet R. Julson, Hooper R. Markert, Nazia Nazam, Swatika Butey, Jerry E. Stewart, Jennifer C. Coleman, James M. Markert, Jianmei W. Leavenworth, Elizabeth A. Beierle
- Open Access
- Radiotherapy
- Research
A comprehensive and longitudinal evaluation of the different populations of lymphoid and myeloid cells in the peripheral blood of patients treated with chemoradiotherapy for head and neck cancer
Jens von der Grün, Martina Broglie, Matthias Guckenberger, Panagiotis Balermpas
- Open Access
- Breast Cancer
- Research
Distribution characteristics of immune infiltration and lymphovascular invasion in patients with breast cancer skin recurrence
Danyang Zhou, Mei Li, Wei Wu, Ying Wu, Qiaohong Nong, Shusen Wang, Ruoxi Hong
- Open Access
- Correction
Correction to: Impact of fludarabine and treosulfan on ovarian tumor cells and mesothelin chimeric antigen receptor T cells
Ibrahim El-Seraf, Isabella Micallef Nilsson, Alina Moter, Zhe Duan, Jonas Mattsson, Isabelle Magalhaes
- Open Access
- Esophageal Cancer
- Research
Impaired TGF-β signaling via AHNAK family mutations elicits an esophageal cancer subtype with sensitivities to genotoxic therapy and immunotherapy
Zihang Mai, Kongjia Luo, Xinye Wang, Xiuying Xie, Lanlan Pang, Hong Yang, Jing Wen, Jianhua Fu
- Open Access
- NSCLC
- Research
Triple therapy boosts survival in NSCLC patients with brain metastases: a retrospective cohort study of chemotherapy, ICIs, and antiangiogenic agents
Dingyi Yang, Erha Munai, Siwei Zeng, Dan Tao, Ze Yuan, Liang Du, Wei Zhou, Yongzhong Wu, Xiao-Dong Zhu
- Open Access
- Cytostatic Therapy
- Research
Adding-on nivolumab to chemotherapy-stabilized patients is associated with improved survival in advanced pancreatic ductal adenocarcinoma
Shih-Hung Yang, Sung-Hsin Kuo, Jen-Chieh Lee, Bang-Bin Chen, Yan-Shen Shan, Yu-Wen Tien, Sz-Chi Chiu, Ann-Lii Cheng, Kun-Huei Yeh
- Open Access
- Sarcoma
- Research
Disruptions in antigen processing and presentation machinery on sarcoma
Salvatore Lorenzo Renne, Laura Sama’, Sonia Kumar, Omer Mintemur, Laura Ruspi, Ilaria Santori, Federico Sicoli, Alexia Bertuzzi, Alice Laffi, Arturo Bonometti, Piergiuseppe Colombo, Vittoria D’amato, Alessandra Bressan, Marta Scorsetti, Luigi Terracciano, Pierina Navarria, Maurizio D’incalci, Vittorio Quagliuolo, Fabio Pasqualini, Fabio Grizzi, Ferdinando Carlo Maria Cananzi
- Open Access
- Research
Secretome and immune cell attraction analysis of head and neck cancers
Tara Muijlwijk, Niels E. Wondergem, Fatima Ekhlas, Naomi Remkes, Dennis N. L. M. Nijenhuis, Lennart Fritz, Sonja H. Ganzevles, Iris H. C. Miedema, C. René Leemans, Jos B. Poell, Ruud H. Brakenhoff, Rieneke van de Ven
- Open Access
- Esophageal Cancer
- Research
Adjuvant chemoradiotherapy plus pembrolizumab for locally advanced esophageal squamous cell carcinoma with high risk of recurrence following neoadjuvant chemoradiotherapy: a single-arm phase II study
Jhe-Cyuan Guo, Ta-Chen Huang, Hung-Yang Kuo, Chia-Chi Lin, Feng-Ming Hsu, Jason Chia-Hsien Cheng, Yen-Lin Huang, Min-Shu Hsieh, Pei-Ming Huang, Jang-Ming Lee, Shu-Ling Wu, Chih-Hung Hsu
- Open Access
- Hepatocellular Carcinoma
- Research
A monoclonal antibody recognizing CD98 on human embryonic stem cells shows anti-tumor activity in hepatocellular carcinoma xenografts
Keunpyo Lim, San Ha Han, Sein Han, Ji Yoon Lee, Hong Seo Choi, Dongho Choi, Chun Jeih Ryu
- Open Access
- Melanoma
- Review
Recent clinical researches and technological development in TIL therapy
Satoko Matsueda, Lei Chen, Hongmei Li, Hui Yao, Fuli Yu
- Open Access
- Gastric Cancer
- Review
Single-cell RNA sequencing to map tumor heterogeneity in gastric carcinogenesis paving roads to individualized therapy
Jiao Xu, Bixin Yu, Fan Wang, Jin Yang
- Open Access
- Checkpoint Inhibitors
- Review
Genomic and molecular alterations associated with primary resistance to immune checkpoint inhibitors
Jyoti Malhotra, Subhajyoti De, Kim Nguyen, Percy Lee, Victoria Villaflor
- Open Access
- Checkpoint Inhibitors
- Research
Bronchoalveolar lavage fluid analysis in patients with checkpoint inhibitor pneumonitis
Ruxuan Chen, Yujie Shi, Nan Fang, Chi Shao, Hui Huang, Ruili Pan, Yan Xu, Mengqi Wang, Xiangning Liu, Kai Xu, Rui Zhu, Mengzhao Wang
- Open Access
- Correction
Correction to: Inhibition of glycolysis enhances the efficacy of immunotherapy via PDK‑mediated upregulation of PD‑L1
Ruizhi Zhang, Gan Mao, Yu Tang, Chong Li, Yisong Gao, Wenxiang Nie, Tianyu Song, Suao Liu, Peng Zhang, Kaixiong Tao, Wei Li