Skip to main content
Top

Cancer and Metastasis Reviews

Issue 4/2025

Content (13 Articles)

Perspectives on the origin and therapeutic opportunities in Down syndrome-associated leukemia

Kunjal Panchal, Jesse Armitage, Laurence C. Cheung, Rishi S. Kotecha, Sébastien Malinge

Precision epigenetic therapies in oncology

Arundhati Chaudhary, Kayleigh J. A. Orchard, Francesca Salani, Theodora Partsou, Mark Eccleston, Guido Bocci, Antoine Italiano, Francesco Crea

Targeting developmental vulnerabilities in childhood sarcomas

Elise Young, Barnaby Kelly, Jason E. Cain

The Bermuda Triangle of paediatric brain cancers: epigenetics, developmental timing window and cell of origin

Afraah Cassim, Yolanda Colino-Sanguino, Sarah L. Fox, Laura Rodriguez de la Fuente, Hannah E. Hartley, Fatima Valdes-Mora

Lung cancer in non-smoking women (LCINSW): from risk factors to precision therapy

Jinming Zhao, Mingjun Li, Limin Niu, Yajing Zhao, Xingguo Song

Single-cell RNA-sequencing of circulating tumour cells: A practical guide to workflow and translational applications

  • Open Access
  • REVIEW

Francis Yew Fu Tieng, Learn-Han Lee, Nurul-Syakima Ab Mutalib

Spatial proteomics for investigating solid tumor resistance mechanisms

Xin Ming M. Zhou, Anjali J. D’Amiano, Charles Lu, Vrinda Madan, Sara Khoshniyati, Jack Kollings, Noah E. Sunshine, Sachin S. Surwase, Joel C. Sunshine

B7-H3 in the tumor microenvironment: Implications for CAR T cell therapy in pediatric solid tumors

Lena Jansen, Judith Wienke, Ronja Molkenbur, Claudia Rossig, Ramona Meissner

Lymphatic metastasis in pancreatic cancer: from bedside to bench and back

Haoyu Shi, Cheng Qin, Yutong Zhao, Bangbo Zhao, Zeru Li, Tianyu Li, Lirui Huang, Weibin Wang

Functions and clinical implications of the liver microenvironment in hepatic uveal melanoma metastases

Camille J. Cunanan, Alyssa B. Sanders, Kayla C. Gallant, Rino S. Seedor, Edward J. Hartsough

Towards a personalized utilization of stereotactic body radiotherapy for the management of liver metastases in solid tumors

Pierre-Antoine Laurent, Kanta Ka, Matthieu Roulleaux Dugage, Antonin Levy, Rastislav Bahleda, Jérôme Durand-Labrunie, Christophe Massard, Eric Deutsch, Roger Sun

Influence of genetic polymorphisms on gefitinib pharmacokinetics and adverse drug reactions in non-small cell lung cancer patients

Prathvi V. Shenoy, Gayathri Baburaj, Rama Rao Damerla, Ananth Pai, Sharada Mailankody, Murali Munisamy, Surulivelrajan Mallayasamy, Karthik S. Udupa, Jill Kolesar, Mahadev Rao

2025 ESMO Congress hub

Unlock your free and exclusive access to expert interviews, news, and more from the annual congress of the European Society for Medical Oncology.

Read more

Keynote webinar | Spotlight on progress in colorectal cancer

  • Live
  • Webinar | 11-12-2025 | 18:00 (CET)

CRC remains a major global health burden, but advances in screening, treatment, and lifestyle-based prevention continue to reshape clinical practice. Gain insights into how the latest research can be leveraged to optimize patient care across the CRC continuum.

Watch it live: Thursday 11 December 2025, 18:00-19:30 (CET)

Prof. Antoni Castells
Prof. Edward Giovannucci
Join the webinar
Webinar

Are you up to date on targeted therapies for relapsed/refractory AML? 

Join Prof. Amer Zeidan and his expert guests to hear about innovations in molecular testing, emerging therapies, and IDH-targeted treatments, and get practical advice for improving your patient care.

Supported by: independent educational grant from Rigel

Find out more
Image Credits
Cancer cell screening and treatment concept/© artacet / iStock / Getty Images Plus, Colon cancer illustration/© (M) KATERYNA KON/SCIENCE PHOTO LIBRARY / Getty Images