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Aesthetic Plastic Surgery
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09-05-2024 | Botulinum Toxin | Review

Botulinum Toxin-A Infiltration to Control Post-Operative Pain after Mastectomy and Expander Reconstruction as Potentially Useful Tool: A Narrative Review

Authors: Giuseppe Andrea Ferraro, Sara Mattiello, Arcangelo Natriello, Giuseppe Lanzano, Giovanni Francesco Nicoletti

Published in: Aesthetic Plastic Surgery | Issue 23/2024

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Abstract

Abstract

Botulinum toxin-A (BTX-A), a neurotoxin produced by Clostridium botulinum, was assessed for relieving implant-related pectoralis major muscle’s painful spasms. In detail, 100 units of BTX-A can reduce muscle activity and, as a consequence, muscle spasms. The latter is considered the leading cause of post-operative pain after the sub-pectoral tissue expansion, sometimes leading to early expanders’ removal. In addition, women choosing post-mastectomy reconstruction surgery seem to suffer worse post-operative pain than those who stop at the mastectomy stage. However, there is no unanimous consensus concerning the potential benefits of BTX-A in reducing pain related to the sub-pectoral placement of tissue expanders in breast reconstruction due to the exiguity of evidence. Therefore, this review aims to describe BTX-A-related evidence in this reconstruction setting.

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Metadata
Title
Botulinum Toxin-A Infiltration to Control Post-Operative Pain after Mastectomy and Expander Reconstruction as Potentially Useful Tool: A Narrative Review
Authors
Giuseppe Andrea Ferraro
Sara Mattiello
Arcangelo Natriello
Giuseppe Lanzano
Giovanni Francesco Nicoletti
Publication date
09-05-2024
Publisher
Springer US
Published in
Aesthetic Plastic Surgery / Issue 23/2024
Print ISSN: 0364-216X
Electronic ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-024-04034-w

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