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BMC Medical Research Methodology

Issue 1/2017

Content (181 Articles)

Clinical prediction in defined populations: a simulation study investigating when and how to aggregate existing models

  • Open Access
  • Research article

Glen P. Martin, Mamas A. Mamas, Niels Peek, Iain Buchan, Matthew Sperrin

Outcome-sensitive multiple imputation: a simulation study

  • Open Access
  • Research article

Evangelos Kontopantelis, Ian R. White, Matthew Sperrin, Iain Buchan

G-computation of average treatment effects on the treated and the untreated

  • Open Access
  • Research article

Aolin Wang, Roch A. Nianogo, Onyebuchi A. Arah

Centralising and optimising decentralised stroke care systems: a simulation study on short-term costs and effects

  • Open Access
  • Research article

Maarten M. H. Lahr, Durk-Jouke van der Zee, Gert-Jan Luijckx, Patrick C. A. J. Vroomen, Erik Buskens

Estimating a population cumulative incidence under calendar time trends

  • Open Access
  • Research Article

Stefan N. Hansen, Morten Overgaard, Per K. Andersen, Erik T. Parner

Erratum to: Sample size calculations for cluster randomised controlled trials with a fixed number of clusters

  • Open Access
  • Erratum

Karla Hemming, Alan J Girling, Alice J Sitch, Jennifer Marsh, Richard J Lilford

Estimating cardiovascular disease incidence from prevalence: a spreadsheet based model

  • Open Access
  • Research article

Xue Feng Hu, Kue Young, Hing Man Chan

Comparison of methods for estimating the attributable risk in the context of survival analysis

  • Open Access
  • Research Article

Malamine Gassama, Jacques Bénichou, Laureen Dartois, Anne C. M. Thiébaut

Multiple triangulation and collaborative research using qualitative methods to explore decision making in pre-hospital emergency care

  • Open Access
  • Research article

Maxine Johnson, Rachel O’Hara, Enid Hirst, Andrew Weyman, Janette Turner, Suzanne Mason, Tom Quinn, Jane Shewan, A. Niroshan Siriwardena

Estimating the size of the homeless adolescent population across seven cities in Cambodia

  • Open Access
  • Research article

Lindsay Stark, Beth L. Rubenstein, Kimchoeun Pak, Rosemary Taing, Gary Yu, Sok Kosal, Leslie Roberts

Psychometric analysis of the brief symptom inventory 18 (BSI-18) in a representative German sample

  • Open Access
  • Research article

Gabriele Helga Franke, Susanne Jaeger, Heide Glaesmer, Claus Barkmann, Katja Petrowski, Elmar Braehler

Measuring health-related quality of life in cervical cancer patients: a systematic review of the most used questionnaires and their validity

  • Open Access
  • Research article

Casper Tax, Marlie E. Steenbergen, Petra L. M. Zusterzeel, Ruud L. M. Bekkers, Maroeska M. Rovers

Assessing and adjusting for non-response in the Millennium Cohort Family Study

  • Open Access
  • Research article

Nida H. Corry, Christianna S. Williams, Mike Battaglia, Hope Seib McMaster, Valerie A. Stander

Evaluation of biases present in the cohort multiple randomised controlled trial design: a simulation study

  • Open Access
  • Research article

Jane Candlish, Alexander Pate, Matthew Sperrin, Tjeerd van Staa

Motivations for (non)participation in population-based health studies among the elderly – comparison of participants and nonparticipants of a prospective study on influenza vaccination

  • Open Access
  • Research article

Manas K. Akmatov, Leonhard Jentsch, Peggy Riese, Marcus May, Malik W. Ahmed, Damaris Werner, Anja Rösel, Jana Prokein, Inga Bernemann, Norman Klopp, Blair Prochnow, Thomas Illig, Christoph Schindler, Carlos A. Guzman, Frank Pessler

Erratum to: A threshold method for immunological correlates of protection

  • Open Access
  • Erratum

Xuan Chen, Fabrice Bailleux, Kamal Desai, Li Qin, Andrew J. Dunning

Efficient confidence limits for adaptive one-arm two-stage clinical trials with binary endpoints

  • Open Access
  • Research Article

Guogen Shan, Hua Zhang, Tao Jiang

Utilising identifier error variation in linkage of large administrative data sources

  • Open Access
  • Research article

Katie Harron, Gareth Hagger-Johnson, Ruth Gilbert, Harvey Goldstein

Testing a systematic approach to identify and prioritise barriers to successful implementation of a complex healthcare intervention

  • Open Access
  • Research article

Louise E. Craig, Leonid Churilov, Liudmyla Olenko, Dominique A. Cadilhac, Rohan Grimley, Simeon Dale, Cintia Martinez-Garduno, Elizabeth McInnes, Julie Considine, Jeremy M. Grimshaw, Sandy Middleton

Self-controlled designs in pharmacoepidemiology involving electronic healthcare databases: a systematic review

  • Open Access
  • Research article

Nathalie Gault, Johann Castañeda-Sanabria, Yann De Rycke, Sylvie Guillo, Stéphanie Foulon, Florence Tubach

Generating evidence on a risk-based monitoring approach in the academic setting – lessons learned

  • Open Access
  • Research article

Belinda von Niederhäusern, Annette Orleth, Sabine Schädelin, Nawal Rawi, Martin Velkopolszky, Claudia Becherer, Pascal Benkert, Priya Satalkar, Matthias Briel, Christiane Pauli-Magnus

On the censored cost-effectiveness analysis using copula information

  • Open Access
  • Research Article

Charles Fontaine, Jean-Pierre Daurès, Paul Landais

A comparison of analytic approaches for individual patient data meta-analyses with binary outcomes

  • Open Access
  • Research article

Doneal Thomas, Robert Platt, Andrea Benedetti

Estimation of treatment preference effects in clinical trials when some participants are indifferent to treatment choice

  • Open Access
  • Research article

Stephen D. Walter, Robin M. Turner, Petra Macaskill, Kirsten J. McCaffery, Les Irwig

Participant retention practices in longitudinal clinical research studies with high retention rates

  • Open Access
  • Research article

Martha Abshire, Victor D. Dinglas, Maan Isabella A. Cajita, Michelle N. Eakin, Dale M. Needham, Cheryl Dennison Himmelfarb

A statistical method utilizing information of imported cases to estimate the transmissibility for an influenza pandemic

  • Open Access
  • Research article

Ka Chun Chong, Benny Chung Ying Zee, Maggie Haitian Wang

Research waste in diagnostic trials: a methods review evaluating the reporting of test-treatment interventions

  • Open Access
  • Research article

Lavinia Ferrante di Ruffano, Jacqueline Dinnes, Sian Taylor-Phillips, Clare Davenport, Chris Hyde, Jonathan J. Deeks

Test-treatment RCTs are susceptible to bias: a review of the methodological quality of randomized trials that evaluate diagnostic tests

  • Open Access
  • Research article

Lavinia Ferrante di Ruffano, Jacqueline Dinnes, Alice J. Sitch, Chris Hyde, Jonathan J. Deeks

Leveraging the EHR4CR platform to support patient inclusion in academic studies: challenges and lessons learned

  • Open Access
  • Research article

Yannick Girardeau, Justin Doods, Eric Zapletal, Gilles Chatellier, Christel Daniel, Anita Burgun, Martin Dugas, Bastien Rance

A systematic review of studies with a representative sample of refugees and asylum seekers living in the community for participation in mental health research

  • Open Access
  • Research article

Joanne C. Enticott, Frances Shawyer, Shiva Vasi, Kimberly Buck, I-Hao Cheng, Grant Russell, Ritsuko Kakuma, Harry Minas, Graham Meadows

AIMD - a validated, simplified framework of interventions to promote and integrate evidence into health practices, systems, and policies

  • Open Access
  • Research article

Peter Bragge, Jeremy M. Grimshaw, Cynthia Lokker, Heather Colquhoun, Lauren Albrecht, Justine Baron, Ann Dadich, Laura Damschroder, Kristin Danko, Maria E. Fernandez, Signe Agnes Flottorp, Heather L. Gainforth, Kate Gooding, Ian D. Graham, Susanne Hempel, Simon Kitto, Jennifer Leeman, Danielle Mazza, Ann McKibbon, Susan Michie, Teryl Nuckols, John Ovretveit, Gjalt-Jorn Y. Peters, Hugo Sax, Shannon D. Scott, Kathleen R. Stevens, Michael G. Wilson

Trial Sequential Analysis in systematic reviews with meta-analysis

  • Open Access
  • Research article

Jørn Wetterslev, Janus Christian Jakobsen, Christian Gluud

Why sample selection matters in exploratory factor analysis: implications for the 12-item World Health Organization Disability Assessment Schedule 2.0

  • Open Access
  • Research article

Cadeyrn J. Gaskin, Sylvie D. Lambert, Steven J. Bowe, Liliana Orellana

The feasibility of matching on a propensity score for acupuncture in a prospective cohort study of patients with chronic pain

  • Open Access
  • Research article

Eric S. Johnson, John F. Dickerson, William M. Vollmer, Alee M. Rowley, Cheryl Ritenbaugh, Richard A. Deyo, Lynn DeBar

Implementation of clinical research trials using web-based and mobile devices: challenges and solutions

  • Open Access
  • Correspondence

Roy Eagleson, Luis Altamirano-Diaz, Alex McInnis, Eva Welisch, Stefanie De Jesus, Harry Prapavessis, Meghan Rombeek, Jamie A. Seabrook, Teresa Park, Kambiz Norozi

Standardizing effect size from linear regression models with log-transformed variables for meta-analysis

  • Open Access
  • Research article

Miguel Rodríguez-Barranco, Aurelio Tobías, Daniel Redondo, Elena Molina-Portillo, María José Sánchez

Incorporating nonlinearity into mediation analyses

  • Open Access
  • Research article

George J. Knafl, Kathleen A. Knafl, Margaret Grey, Jane Dixon, Janet A. Deatrick, Agatha M. Gallo

Methods for conceptualising ‘visual ability’ as a measurable construct in children with cerebral palsy

  • Open Access
  • Research article

Belinda Deramore Denver, Margareta Adolfsson, Elspeth Froude, Peter Rosenbaum, Christine Imms

Erratum to: Evaluation of biases present in the cohort multiple randomised controlled trial design: a simulation study

  • Open Access
  • Erratum

Jane Candlish, Alexander Pate, Matthew Sperrin, Tjeerd van Staa

The effect of postal questionnaire burden on response rate and answer patterns following admission to intensive care: a randomised controlled trial

  • Open Access
  • Research article

Robert Hatch, Duncan Young, Vicki Barber, David A Harrison, Peter Watkinson

Practical partnered research to improve weight loss among overweight/obese veterans: lessons from the trenches

  • Open Access
  • Correspondence

Mona AuYoung, Laura J. Damschroder, Linda Kinsinger, Tannaz Moin, Caroline R. Richardson

The importance of censoring in competing risks analysis of the subdistribution hazard

  • Open Access
  • Research Article

Mark W. Donoghoe, Val Gebski

Time-dependent ROC curve analysis in medical research: current methods and applications

  • Open Access
  • Research article

Adina Najwa Kamarudin, Trevor Cox, Ruwanthi Kolamunnage-Dona

Comparison of surveillance-based metrics for the assessment and monitoring of disease detection: simulation study about type 2 diabetes

  • Open Access
  • Research Article

Ralph Brinks, Annika Hoyer, Deborah B. Rolka, Oliver Kuss, Edward W. Gregg

Estimating the standardized incidence ratio (SIR) with incomplete follow-up data

  • Open Access
  • Research article

Heiko Becher, Volker Winkler

Practical application of opt-out recruitment methods in two health services research studies

  • Open Access
  • Research article

Christopher J. Miller, James F. Burgess Jr., Ellen P. Fischer, Deborah J. Hodges, Lindsay K. Belanger, Jessica M. Lipschitz, Siena R. Easley, Christopher J. Koenig, Regina L. Stanley, Jeffrey M. Pyne

Statistical evaluation of adding multiple risk factors improves Framingham stroke risk score

  • Open Access
  • Research article

Xiao-Hua Zhou, Xiaonan Wang, Ashlee Duncan, Guizhou Hu, Jiayin Zheng

Clinical patient registry recruitment and retention: a survey of patients in two chronic disease registries

  • Open Access
  • Research article

Daniel H. Solomon, Nancy A. Shadick, Michael E. Weinblatt, Michelle Frits, Christine Iannaccone, Agnes Zak, Joshua R. Korzenik

Review and evaluation of performance measures for survival prediction models in external validation settings

  • Open Access
  • Research article

M. Shafiqur Rahman, Gareth Ambler, Babak Choodari-Oskooei, Rumana Z. Omar

Protocol for the development of a salutogenic intrapartum core outcome set (SIPCOS)

  • Open Access
  • Study protocol

Valerie Smith, Deirdre Daly, Ingela Lundgren, Tine Eri, Cecily Begley, Mechthild M. Gross, Soo Downe, Zarko Alfirevic, Declan Devane

Kappa statistic to measure agreement beyond chance in free-response assessments

  • Open Access
  • Research article

Marc Carpentier, Christophe Combescure, Laura Merlini, Thomas V. Perneger

Impact of correlation of predictors on discrimination of risk models in development and external populations

  • Open Access
  • Research article

Suman Kundu, Madhu Mazumdar, Bart Ferket

The impact of the mode of survey administration on estimates of daily smoking for mobile phone only users

  • Open Access
  • Research article

Joseph Hanna, Damien V. Cordery, David G. Steel, Walter Davis, Timothy C. Harrold

Does the association between adherence to statin medications and mortality depend on measurement approach? A retrospective cohort study

  • Open Access
  • Research article

Mhd. Wasem Alsabbagh, Dean Eurich, Lisa M. Lix, Thomas W. Wilson, David F. Blackburn

Treatment-seeking behaviour in low- and middle-income countries estimated using a Bayesian model

  • Open Access
  • Research article

Victor A. Alegana, Jim Wright, Carla Pezzulo, Andrew J. Tatem, Peter M. Atkinson

Assessing the impact of natural policy experiments on socioeconomic inequalities in health: how to apply commonly used quantitative analytical methods?

  • Open Access
  • Research article

Yannan Hu, Frank J. van Lenthe, Rasmus Hoffmann, Karen van Hedel, Johan P. Mackenbach

Evaluation of a modified version of the Posttraumatic Growth Inventory-Short Form

  • Open Access
  • Research article

Navjot Kaur, Ben Porter, Cynthia A. LeardMann, Laura E. Tobin, Hector Lemus, David D. Luxton, Richard Armenta, Lauren Bauer, Deb Bookwalter, Anna Bukowinski, Adam Cooper, James Davies, Alex Esquivel, Dennis Faix, Susan Farrish, Toni Rose Geronimo, Gia Gumbs, Isabel Jacobson, Claire Kolaja, Joyce Kong, William Lee, Kyna Long, Denise Lovec-Jenkins, Gordon Lynch, Rayna Matsuno, Danielle Mitchell, Kristin Motylinski, Anna Nagel, Chiping Nieh, Chris O’Malley, Serguey Parkhomovsky, Anet Petrosyan, Chris Phillips, Teresa Powell, Rudy Rull, Beverly Sheppard, Steven Speigle, Daniel Trone, Jennifer Walstrom, Paul Amoroso, Edward Boyko, Gary Gackstetter, Greg Gray, Tomoko Hooper, Margaret Ryan, Tyler Smith, Timothy Wells

Using evaluability assessment to assess local community development health programmes: a Scottish case-study

  • Open Access
  • Research article

Melissa Belford, Tony Robertson, Ruth Jepson

Evaluation of the impact of disease prevention measures: a methodological note on defining incidence rates

  • Open Access
  • Research article

Yin-Bun Cheung, Ying Xu, Matthew Cairns, Paul Milligan

An experimental comparison of web-push vs. paper-only survey procedures for conducting an in-depth health survey of military spouses

  • Open Access
  • Research article

Hope Seib McMaster, Cynthia A. LeardMann, Steven Speigle, Don A. Dillman, Valerie Stander, Jackie Pflieger, Carlos Carballo, Teresa Powell, Kelly Woodall, Evelyn Sun, Lauren Bauer, William Lee, Nida Corry, Christianna Williams, John Fairbank, Robert Murphy, Ernestine Briggs-King, Ellen Gerrity, Robert Lee

Measurement properties of the Danish version of the Awareness and Beliefs about Cancer (ABC) measure

  • Open Access
  • Research article

Line Hvidberg, Anette Fischer Pedersen, Christian Nielsen Wulff, Anders Helles Carlsen, Peter Vedsted

Sample size and power determination when limited preliminary information is available

  • Open Access
  • Research article

Christine E. McLaren, Wen-Pin Chen, Thomas D. O’Sullivan, Daniel L. Gillen, Min-Ying Su, Jeon H. Chen, Bruce J. Tromberg

Assessing the complexity of interventions within systematic reviews: development, content and use of a new tool (iCAT_SR)

  • Open Access
  • Technical advance

Simon Lewin, Maggie Hendry, Jackie Chandler, Andrew D. Oxman, Susan Michie, Sasha Shepperd, Barnaby C. Reeves, Peter Tugwell, Karin Hannes, Eva A. Rehfuess, Vivien Welch, Joanne E. Mckenzie, Belinda Burford, Jennifer Petkovic, Laurie M. Anderson, Janet Harris, Jane Noyes

The effectiveness of a monetary incentive offer on survey response rates and response completeness in a longitudinal study

  • Open Access
  • Research article

Shengchao Yu, Howard E. Alper, Angela-Maithy Nguyen, Robert M. Brackbill, Lennon Turner, Deborah J. Walker, Carey B. Maslow, Kimberly C. Zweig

Double-adjustment in propensity score matching analysis: choosing a threshold for considering residual imbalance

  • Open Access
  • Research article

Tri-Long Nguyen, Gary S. Collins, Jessica Spence, Jean-Pierre Daurès, P. J. Devereaux, Paul Landais, Yannick Le Manach

On comparison of net survival curves

  • Open Access
  • Research Article

Klemen Pavlič, Maja Pohar Perme

On the impact of nonresponse in logistic regression: application to the 45 and Up study

  • Open Access
  • Research article

Joanna J. J. Wang, Mark Bartlett, Louise Ryan

Overview of systematic reviews of therapeutic ranges: methodologies and recommendations for practice

  • Open Access
  • Research article

Lewis Cooney, Yoon K. Loke, Su Golder, Jamie Kirkham, Andrea Jorgensen, Ian Sinha, Daniel Hawcutt

Validity of self-reported weight and height: a cross-sectional study among Malaysian adolescents

  • Open Access
  • Research article

C. C. Kee, K. H. Lim, M. G. Sumarni, C. H. Teh, Y. Y. Chan, M. I. Nuur Hafizah, Y. K. Cheah, E. O. Tee, Y. Ahmad Faudzi, M. Amal Nasir

Bayesian hierarchical piecewise regression models: a tool to detect trajectory divergence between groups in long-term observational studies

  • Open Access
  • Research article

Marie-jeanne Buscot, Simon S. Wotherspoon, Costan G. Magnussen, Markus Juonala, Matthew A. Sabin, David P. Burgner, Terho Lehtimäki, Jorma S. A. Viikari, Nina Hutri-Kähönen, Olli T. Raitakari, Russell J. Thomson

A nonparametric multiple imputation approach for missing categorical data

  • Open Access
  • Research Article

Muhan Zhou, Yulei He, Mandi Yu, Chiu-Hsieh Hsu

Methodologic considerations in the design and analysis of nested case-control studies: association between cytokines and postoperative delirium

  • Open Access
  • Research article

Long H. Ngo, Sharon K. Inouye, Richard N. Jones, Thomas G. Travison, Towia A. Libermann, Simon T. Dillon, George A. Kuchel, Sarinnapha M. Vasunilashorn, David C. Alsop, Edward R. Marcantonio

Limitations of pulmonary embolism ICD-10 codes in emergency department administrative data: let the buyer beware

  • Open Access
  • Research article

Kristin Burles, Grant Innes, Kevin Senior, Eddy Lang, Andrew McRae

Simulation of complex data structures for planning of studies with focus on biomarker comparison

  • Open Access
  • Research Article

Andreas Schulz, Daniela Zöller, Stefan Nickels, Manfred E. Beutel, Maria Blettner, Philipp S. Wild, Harald Binder

Erratum to: Standardizing effect size from linear regression models with log-transformed variables for meta-analysis

  • Open Access
  • Erratum

Miguel Rodríguez-Barranco, Aurelio Tobías, Daniel Redondo, Elena Molina-Portillo, María José Sánchez

A DAG-based comparison of interventional effect underestimation between composite endpoint and multi-state analysis in cardiovascular trials

  • Open Access
  • Research Article

Antje Jahn-Eimermacher, Katharina Ingel, Stella Preussler, Antoni Bayes-Genis, Harald Binder

Inverse probability of treatment-weighted competing risks analysis: an application on long-term risk of urinary adverse events after prostate cancer treatments

  • Open Access
  • Research article

Charlotte A. Bolch, Haitao Chu, Stephanie Jarosek, Stephen R. Cole, Sean Elliott, Beth Virnig

Selection bias and subject refusal in a cluster-randomized controlled trial

  • Open Access
  • Research article

Rochelle Yang, Barry L. Carter, Tyler H. Gums, Brian M. Gryzlak, Yinghui Xu, Barcey T. Levy

Estimating parameters for probabilistic linkage of privacy-preserved datasets

  • Open Access
  • Research article

Adrian P. Brown, Sean M. Randall, Anna M. Ferrante, James B. Semmens, James H. Boyd

Barriers to publishing in biomedical journals perceived by a sample of French researchers: results of the DIAzePAM study

  • Open Access
  • Research article

Martin Duracinsky, Christophe Lalanne, Laurence Rous, Aichata Fofana Dara, Lesya Baudoin, Claire Pellet, Alexandre Descamps, Fabienne Péretz, Olivier Chassany

Inter-rater reliability of AMSTAR is dependent on the pair of reviewers

  • Open Access
  • Research article

Dawid Pieper, Anja Jacobs, Beate Weikert, Alba Fishta, Uta Wegewitz

Awareness of wearing an accelerometer does not affect physical activity in youth

  • Open Access
  • Research article

Jérémy Vanhelst, Laurent Béghin, Elodie Drumez, Stéphanie Coopman, Frédéric Gottrand

Implementation fidelity of a self-management course for epilepsy: method and assessment

  • Open Access
  • Research article

G. Wojewodka, S. Hurley, S. J. C. Taylor, A. J. Noble, L. Ridsdale, L. H. Goldstein

Cost and yield considerations when expanding recruitment for genetic studies: the primary open-angle African American glaucoma genetics study

  • Open Access
  • Research article

Rebecca Salowe, Laura O’Keefe, Sayaka Merriam, Roy Lee, Naira Khachatryan, Prithvi Sankar, Eydie Miller-Ellis, Amanda Lehman, Victoria Addis, Windell Murphy, Jeffrey Henderer, Maureen Maguire, Joan O’Brien

Sample size re-estimation in paired comparative diagnostic accuracy studies with a binary response

  • Open Access
  • Technical advance

Gareth P. J. McCray, Andrew C. Titman, Paula Ghaneh, Gillian A. Lancaster

Accounting for treatment use when validating a prognostic model: a simulation study

  • Open Access
  • Research article

Romin Pajouheshnia, Linda M. Peelen, Karel G. M. Moons, Johannes B. Reitsma, Rolf H. H. Groenwold

Using structural equation modeling for network meta-analysis

  • Open Access
  • Research article

Yu-Kang Tu, Yun-Chun Wu

Nonlinear joint models for individual dynamic prediction of risk of death using Hamiltonian Monte Carlo: application to metastatic prostate cancer

  • Open Access
  • Research Article

Solène Desmée, France Mentré, Christine Veyrat-Follet, Bernard Sébastien, Jérémie Guedj

Protocol adherence for continuously titrated interventions in randomized trials: an overview of the current methodology and case study

  • Open Access
  • Debate

F. Lauzier, N. K. Adhikari, A. Seely, K. K. Y. Koo, E. P. Belley-Côté, K. E. A. Burns, D. J. Cook, F. D’Aragon, B. Rochwerg, M. E. Kho, S. J. W. Oczkowksi, E. H. Duan, M. O. Meade, A. G. Day, F. Lamontagne

A random effects meta-analysis model with Box-Cox transformation

  • Open Access
  • Research Article

Yusuke Yamaguchi, Kazushi Maruo, Christopher Partlett, Richard D. Riley

Basic parametric analysis for a multi-state model in hospital epidemiology

  • Open Access
  • Research Article

Maja von Cube, Martin Schumacher, Martin Wolkewitz

Implementing the EffTox dose-finding design in the Matchpoint trial

  • Open Access
  • Research Article

Kristian Brock, Lucinda Billingham, Mhairi Copland, Shamyla Siddique, Mirjana Sirovica, Christina Yap

Integrating data from randomized controlled trials and observational studies to predict the response to pregabalin in patients with painful diabetic peripheral neuropathy

  • Open Access
  • Research article

Joe Alexander, Roger A. Edwards, Alberto Savoldelli, Luigi Manca, Roberto Grugni, Birol Emir, Ed Whalen, Stephen Watt, Marina Brodsky, Bruce Parsons

A comparison of multiple imputation methods for handling missing values in longitudinal data in the presence of a time-varying covariate with a non-linear association with time: a simulation study

  • Open Access
  • Research article

Anurika Priyanjali De Silva, Margarita Moreno-Betancur, Alysha Madhu De Livera, Katherine Jane Lee, Julie Anne Simpson

Programme Reporting Standards (PRS) for improving the reporting of sexual, reproductive, maternal, newborn, child and adolescent health programmes

  • Open Access
  • Research article

Anna E. Kågesten, Özge Tunçalp, Anayda Portela, Moazzam Ali, Nhan Tran, A. Metin Gülmezoglu

Validity and reliability of a Malay version of the brief illness perception questionnaire for patients with type 2 diabetes mellitus

  • Open Access
  • Research article

Boon-How Chew, Rimke C. Vos, Monique Heijmans, Sazlina Shariff-Ghazali, Aaron Fernandez, Guy E. H. M. Rutten

Choice of futility boundaries for group sequential designs with two endpoints

  • Open Access
  • Research Article

Svenja Schüler, Meinhard Kieser, Geraldine Rauch

Using classification and regression tree modelling to investigate response shift patterns in dentine hypersensitivity

  • Open Access
  • Research article

Carolina Machuca, Mario V. Vettore, Marta Krasuska, Sarah R. Baker, Peter G. Robinson

Trading certainty for speed - how much uncertainty are decisionmakers and guideline developers willing to accept when using rapid reviews: an international survey

  • Open Access
  • Research article

Gernot Wagner, Barbara Nussbaumer-Streit, Judith Greimel, Agustín Ciapponi, Gerald Gartlehner

Applied Swarm-based medicine: collecting decision trees for patterns of algorithms analysis

  • Open Access
  • Research article

Cédric M. Panje, Markus Glatzer, Joscha von Rappard, Christian Rothermundt, Thomas Hundsberger, Valentin Zumstein, Ludwig Plasswilm, Paul Martin Putora

Estimating correlation between multivariate longitudinal data in the presence of heterogeneity

  • Open Access
  • Research article

Feng Gao, J. Philip Miller, Chengjie Xiong, Jingqin Luo, Julia A. Beiser, Ling Chen, Mae O. Gordon

The impact of self-interviews on response patterns for sensitive topics: a randomized trial of electronic delivery methods for a sexual behaviour questionnaire in rural South Africa

  • Open Access
  • Research article

Guy Harling, Dumile Gumede, Tinofa Mutevedzi, Nuala McGrath, Janet Seeley, Deenan Pillay, Till W. Bärnighausen, Abraham J. Herbst

Statistical methods for elimination of guarantee-time bias in cohort studies: a simulation study

  • Open Access
  • Research article

In Sung Cho, Ye Rin Chae, Ji Hyeon Kim, Hae Rin Yoo, Suk Yong Jang, Gyu Ri Kim, Chung Mo Nam

Using Bayesian statistics to estimate the likelihood a new trial will demonstrate the efficacy of a new treatment

  • Open Access
  • Research article

David J. Biau, Samuel Boulezaz, Laurent Casabianca, Moussa Hamadouche, Philippe Anract, Sylvie Chevret

Trends in the number and the quality of trial protocols involving children submitted to a French Institutional Review Board

  • Open Access
  • Research article

Isabelle Gautier, Perrine Janiaud, Nelly Rollet, Nicolas André, Michel Tsimaratos, Catherine Cornu, Salma Malik, Stéphanie Gentile, Behrouz Kassaï

Validity and reliability of a performance evaluation tool based on the modified Barthel Index for stroke patients

  • Open Access
  • Research article

Tomoko Ohura, Kimitaka Hase, Yoshie Nakajima, Takeo Nakayama

Factors associated with attrition in a longitudinal online study: results from the HaBIDS panel

  • Open Access
  • Research article

Nicole Rübsamen, Manas K. Akmatov, Stefanie Castell, André Karch, Rafael T. Mikolajczyk

Longitudinal studies that use data collected as part of usual care risk reporting biased results: a systematic review

  • Open Access
  • Research article

Delaram Farzanfar, Asmaa Abumuamar, Jayoon Kim, Emily Sirotich, Yue Wang, Eleanor Pullenayegum

Multiple imputation for handling missing outcome data when estimating the relative risk

  • Open Access
  • Research article

Thomas R. Sullivan, Katherine J. Lee, Philip Ryan, Amy B. Salter

Evidence mapping based on systematic reviews of therapeutic interventions for gastrointestinal stromal tumors (GIST)

  • Open Access
  • Research article

Mónica Ballesteros, Nadia Montero, Antonio López-Pousa, Gerard Urrútia, Ivan Solà, Gabriel Rada, Hector Pardo-Hernandez, Xavier Bonfill

Addressing data privacy in matched studies via virtual pooling

  • Open Access
  • Research article

P. Saha-Chaudhuri, C.R. Weinberg

Monte Carlo simulation-based estimation for the minimum mortality temperature in temperature-mortality association study

  • Open Access
  • Research article

Whanhee Lee, Ho Kim, Sunghee Hwang, Antonella Zanobetti, Joel D. Schwartz, Yeonseung Chung

Conducting a team-based multi-sited focused ethnography in primary care

  • Open Access
  • Correspondence

A.P. Bikker, H. Atherton, H. Brant, T. Porqueddu, J.L. Campbell, A. Gibson, B. McKinstry, C. Salisbury, S. Ziebland

Measuring the burden of treatment for chronic disease: implications of a scoping review of the literature

  • Open Access
  • Research article

Adem Sav, Asiyeh Salehi, Frances S. Mair, Sara S. McMillan

Assessment of consent models as an ethical consideration in the conduct of prehospital ambulance randomised controlled clinical trials: a systematic review

  • Open Access
  • Research article

Stephanie Armstrong, Adele Langlois, Despina Laparidou, Mark Dixon, Jason P. Appleton, Philip M. Bath, Helen Snooks, A. Niroshan Siriwardena

Repeat: a framework to assess empirical reproducibility in biomedical research

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Leslie D. McIntosh, Anthony Juehne, Cynthia R. H. Vitale, Xiaoyan Liu, Rosalia Alcoser, J. Christian Lukas, Bradley Evanoff

Pragmatic clinical trials embedded in healthcare systems: generalizable lessons from the NIH Collaboratory

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Kevin P. Weinfurt, Adrian F. Hernandez, Gloria D. Coronado, Lynn L. DeBar, Laura M. Dember, Beverly B. Green, Patrick J. Heagerty, Susan S. Huang, Kathryn T. James, Jeffrey G. Jarvik, Eric B. Larson, Vincent Mor, Richard Platt, Gary E. Rosenthal, Edward J. Septimus, Gregory E. Simon, Karen L. Staman, Jeremy Sugarman, Miguel Vazquez, Douglas Zatzick, Lesley H. Curtis

Patients’ beliefs regarding informed consent for low-risk pragmatic trials

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Rafael Dal-Ré, Antonio J. Carcas, Xavier Carné, David Wendler

Systematic review of statistical approaches to quantify, or correct for, measurement error in a continuous exposure in nutritional epidemiology

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Derrick A. Bennett, Denise Landry, Julian Little, Cosetta Minelli

Predicting the multi-domain progression of Parkinson’s disease: a Bayesian multivariate generalized linear mixed-effect model

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Ming Wang, Zheng Li, Eun Young Lee, Mechelle M. Lewis, Lijun Zhang, Nicholas W. Sterling, Daymond Wagner, Paul Eslinger, Guangwei Du, Xuemei Huang

Item response models for the longitudinal analysis of health-related quality of life in cancer clinical trials

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Antoine Barbieri, Jean Peyhardi, Thierry Conroy, Sophie Gourgou, Christian Lavergne, Caroline Mollevi

Recruiting former melanoma patients via hospitals in comparison to office-based dermatologists in a register-based cohort study that required indirect contact

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S. R. Zeissig, V. Weyer-Elberich, K. Emrich, H. Binder, S. Fischbeck, B. H. Imruck, P. Friedrich-Mai, M. E. Beutel, M. Blettner

Is the information of systematic reviews published in nursing journals up-to-date? a cross-sectional study

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Wilson W. S. Tam, Kenneth K. H. Lo, Parames Khalechelvam, Joey Seah, Shawn Y. S. Goh

Frequency of data extraction errors and methods to increase data extraction quality: a methodological review

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Tim Mathes, Pauline Klaßen, Dawid Pieper

Mobile electronic versus paper case report forms in clinical trials: a randomized controlled trial

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Robert Fleischmann, Anne-Marie Decker, Antje Kraft, Knut Mai, Sein Schmidt

Performance comparison of first-order conditional estimation with interaction and Bayesian estimation methods for estimating the population parameters and its distribution from data sets with a low number of subjects

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Sudeep Pradhan, Byungjeong Song, Jaeyeon Lee, Jung-woo Chae, Kyung Im Kim, Hyun-moon Back, Nayoung Han, Kwang-il Kwon, Hwi-yeol Yun

New methods for estimating follow-up rates in cohort studies

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Xiaonan Xue, Ilir Agalliu, Mimi Y. Kim, Tao Wang, Juan Lin, Reza Ghavamian, Howard D. Strickler

Sample size calculations based on a difference in medians for positively skewed outcomes in health care studies

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Aidan G. O’Keeffe, Gareth Ambler, Julie A. Barber

What does it mean when people say that they have received expressions of concern about their drinking or advice to cut down on the AUDIT scale?

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John A. Cunningham, Alexandra Godinho, Vladyslav Kushnir, Nicolas Bertholet

ERDO - a framework to select an appropriate randomization procedure for clinical trials

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Ralf-Dieter Hilgers, Diane Uschner, William F. Rosenberger, Nicole Heussen

Performance of the marginal structural cox model for estimating individual and joined effects of treatments given in combination

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Clovis Lusivika-Nzinga, Hana Selinger-Leneman, Sophie Grabar, Dominique Costagliola, Fabrice Carrat

Classification schemes for knowledge translation interventions: a practical resource for researchers

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Susan E. Slaughter, Gabrielle L. Zimmermann, Megan Nuspl, Heather M. Hanson, Lauren Albrecht, Rosmin Esmail, Khara Sauro, Amanda S. Newton, Maoliosa Donald, Michele P. Dyson, Denise Thomson, Lisa Hartling

When and how should multiple imputation be used for handling missing data in randomised clinical trials – a practical guide with flowcharts

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Janus Christian Jakobsen, Christian Gluud, Jørn Wetterslev, Per Winkel

Validity of mobile electronic data capture in clinical studies: a pilot study in a pediatric population

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Belinda von Niederhäusern, Ramon Saccilotto, Sabine Schädelin, Victoria Ziesenitz, Pascal Benkert, Marie-Luise Decker, Anya Hammann, Julia Bielicki, Marc Pfister, Christiane Pauli-Magnus

Longitudinal drop-out and weighting against its bias

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Steffen C. E. Schmidt, Alexander Woll

Methods to perform systematic reviews of patient preferences: a literature survey

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Tsung Yu, Nomin Enkh-Amgalan, Ganchimeg Zorigt

Learning from older peoples’ reasons for participating in demanding, intensive epidemiological studies: a qualitative study

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Alicja M. Baczynska, Sarah C. Shaw, Harnish P. Patel, Avan A. Sayer, Helen C. Roberts

Accounting for misclassification bias of binary outcomes due to underscreening: a sensitivity analysis

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Nanhua Zhang, Si Cheng, Lilliam Ambroggio, Todd A. Florin, Maurizio Macaluso

User testing of an adaptation of fishbone diagrams to depict results of systematic reviews

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Gerald Gartlehner, Marie-Therese Schultes, Viktoria Titscher, Laura C. Morgan, Georgiy V. Bobashev, Peyton Williams, Suzanne L. West

Multiple Score Comparison: a network meta-analysis approach to comparison and external validation of prognostic scores

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Sarah R. Haile, Beniamino Guerra, Joan B. Soriano, Milo A. Puhan, Bernd Lamprecht, Ana S. Ramírez, Pablo Martinez-Camblor, Bernhard Kaiser, Inmaculada Alfageme, Pere Almagro, Ciro Casanova, Cristóbal Esteban-González, Juan J. Soler-Cataluña, Juan P. de Torres, Marc. Miravitlles, Bartolome R. Celli, Jose M. Marin, Gerben ter Riet, Patricia Sobradillo-Ecenarro, Peter Lange, Judith Garcia-Aymerich, Josep M. Antó-Boqué, Alice M. Turner, Meilan K. Han, Arnulf Langhammer, Linda Leivseth, Per Bakke, Ane Johannessen, Oga Toru, Borja Cosío, Julio Ancochea-Bermúdez, Andres Echazarreta, Nicolas Roche, Pierre-Régis Burgel, Don D. Sin, Joan B. Soriano, Milo A. Puhan

The development of CHAMP: a checklist for the appraisal of moderators and predictors

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Ralph van Hoorn, Marcia Tummers, Andrew Booth, Ansgar Gerhardus, Eva Rehfuess, Daniel Hind, Patrick M. Bossuyt, Vivian Welch, Thomas P. A. Debray, Martin Underwood, Pim Cuijpers, Helena Kraemer, Gert Jan van der Wilt, Wietkse Kievit

Development of an intervention to reduce antibiotic use for childhood coughs in UK primary care using critical synthesis of multi-method research

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Patricia J. Lucas, Jenny Ingram, Niamh M. Redmond, Christie Cabral, Sophie L. Turnbull, Alastair D. Hay

A survey of prevalence of narrative and systematic reviews in five major medical journals

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Clovis Mariano Faggion Jr, Nikolaos P. Bakas, Jason Wasiak

The alarming problems of confounding equivalence using logistic regression models in the perspective of causal diagrams

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Yuanyuan Yu, Hongkai Li, Xiaoru Sun, Ping Su, Tingting Wang, Yi Liu, Zhongshang Yuan, Yanxun Liu, Fuzhong Xue

Compliance of systematic reviews in ophthalmology with the PRISMA statement

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Seon-Young Lee, Harkiran Sagoo, Reem Farwana, Katharine Whitehurst, Alex Fowler, Riaz Agha

Can statistic adjustment of OR minimize the potential confounding bias for meta-analysis of case-control study? A secondary data analysis

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Tianyi Liu, Xiaolu Nie, Zehao Wu, Ying Zhang, Guoshuang Feng, Siyu Cai, Yaqi Lv, Xiaoxia Peng

Abstract analysis method facilitates filtering low-methodological quality and high-bias risk systematic reviews on psoriasis interventions

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Francisco Gómez-García, Juan Ruano, Macarena Aguilar-Luque, Patricia Alcalde-Mellado, Jesús Gay-Mimbrera, José Luis Hernández-Romero, Juan Luis Sanz-Cabanillas, Beatriz Maestre-López, Marcelino González-Padilla, Pedro J. Carmona-Fernández, Antonio Vélez García-Nieto, Beatriz Isla-Tejera

A scoping review of comparisons between abstracts and full reports in primary biomedical research

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Guowei Li, Luciana P. F. Abbade, Ikunna Nwosu, Yanling Jin, Alvin Leenus, Muhammad Maaz, Mei Wang, Meha Bhatt, Laura Zielinski, Nitika Sanger, Bianca Bantoto, Candice Luo, Ieta Shams, Hamnah Shahid, Yaping Chang, Guangwen Sun, Lawrence Mbuagbaw, Zainab Samaan, Mitchell A. H. Levine, Jonathan D. Adachi, Lehana Thabane