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BMC Complementary Medicine and Therapies

Issue 1/2022

Content (342 Articles)

Economic evaluation of a national vitamin D supplementation program among Iranian adolescents for the prevention of adulthood type 2 diabetes mellitus

Narges Zandieh, Mohsen Rezaei Hemami, Ali Darvishi, Seyed Mohammad Hasheminejad, Zahra Abdollahi, Maryam Zarei, Ramin Heshmat

The neuromuscular responses in patients with Parkinson’s disease under different conditions during whole-body vibration training

Chia-Ming Chang, Chon-Haw Tsai, Ming-Kuei Lu, Hsin-Chun Tseng, Grace Lu, Bey-Ling Liu, Hsiu-Chen Lin

Does tai chi improve psychological well-being and quality of life in patients with cardiovascular disease and/or cardiovascular risk factors? A systematic review

Guoyan Yang, Wenyuan Li, Nerida Klupp, Huijuan Cao, Jianping Liu, Alan Bensoussan, Hosen Kiat, Diana Karamacoska, Dennis Chang

Neuroprotective effects of Lippia javanica (Burm.F.) Spreng. Herbal tea infusion on Lead-induced oxidative brain damage in Wistar rats

  • Open Access
  • Research

Zubair Suleman, Godwill A. Engwa, Mathulo Shauli, Hannibal T. Musarurwa, Ndinashe A. Katuruza, Constance R. Sewani-Rusike

Trifolium pratense ethanolic extract alters the gut microbiota composition and regulates serum lipid profile in the ovariectomized rats

Yixian Quah, Na-Hye Park, Eon-Bee Lee, Ki-Ja Lee, Jireh Chan Yi-Le, Md. Sekendar Ali, Seung-Hee Jang, Min-Jeong Kim, Seung-Jin Lee, Seung-Chun Park

Protective effects of Quercus acuta Thunb. fruit extract against UVB-induced photoaging through ERK/AP-1 signaling modulation in human keratinocytes

  • Open Access
  • Research

Ji-Ae Hong, Donghyuk Bae, Kyo-Nyeo Oh, Dool-Ri Oh, Yujin Kim, Yonguk Kim, So Jeong Im, Eun-jin Choi, Seul-gi Lee, Moonjong Kim, Changsik Jeong, Chul Yung Choi

Optimization for ultrasonic-microwave synergetic extraction of total iridoid glycosides and screening of analgesic and anti-inflammatory active fractions from patrinia scabra Bunge (Valerianaceae)

Quhuan Ma, Yanmei Lu, Yi Deng, Xiaodong Hu, Wanyu Li, Hongzhen Jia, Yuer Guo, Xiaofeng Shi

Evaluation of the antidiarrheal activity of 80% methanol extract and solvent fractions of the leaf of Bersama abyssinica fresen (Melianthaceae) in mice

Mihret Ayalew, Azmeraw Bekele, Mestayet Geta Mengistie, Seyfe Asrade Atnafie

Discovery and identification of potential anti-melanogenic active constituents of Bletilla striata by zebrafish model and molecular docking

Yiyuan Luo, Juan Wang, Shuo Li, Yue Wu, Zhirui Wang, Shaojun Chen, Hongjiang Chen

Acacetin inhibits invasion, migration and TGF-β1-induced EMT of gastric cancer cells through the PI3K/Akt/Snail pathway

Guangtao Zhang, Zhaoyan Li, Jiahuan Dong, Weili Zhou, Zhanxia Zhang, Zujun Que, Xiaohong Zhu, Yan Xu, Nida Cao, Aiguang Zhao

Euterpe oleracea fruit (Açai)-enriched diet suppresses the development of experimental cerebral malaria induced by Plasmodium berghei (ANKA) infection

Karen Renata Herculano Matos Oliveira, Marjorie Lujan Marques Torres, Nayara Kauffmann, Brenda Jaqueline de Azevedo Ataíde, Nívia de Souza Franco Mendes, Larissa Medeiros dos Anjos, Rosivaldo dos Santos Borges, Carlomagno Pacheco Bahia, Luana Ketlen Reis Leão, Adelaide da Conceição Fonseca Passos, Anderson Manoel Herculano, Evander de Jesus Oliveira Batista

Effectiveness of maturity of Rubus occidentalis on hyperalgesia induced by acidic saline injection in rats

Geun Joo Choi, Hyun Kang, Oh Haeng Lee, Eun Jin Ahn, Fletcher A. White, Ye Jin Cho, Chong Wha Baek, Yong Hun Jung, Ji Wung Kwon

Panax notoginseng saponins reverse P-gp-mediated steroid resistance in lupus: involvement in the suppression of the SIRT1/FoxO1/MDR1 signalling pathway in lymphocytes

Feng Pan, Yue-jin Li, Ying Lu

Traditional and complementary medicine (TCM) usage and its association with Patient Assessment of Chronic Illness Care (PACIC) among individuals with metabolic syndrome in primary care

  • Open Access
  • Care
  • Research

Nor Farha Basri, Anis Safura Ramli, Mariam Mohamad, Khairatul Nainey Kamaruddin

The effect of Kappaphycus alvarezii active fraction on oxidative stress and inflammation in streptozotocin and nicotinamide-induced diabetic rats

  • Open Access
  • Research article

Evy Yulianti, Sunarti, Mae Sri Hartati Wahyuningsih

Acute and sub-acute oral toxicity of aqueous whole leaf and green rind extracts of Aloe vera in Wistar rats

  • Open Access
  • Research

Florence Nalimu, Joseph Oloro, Emanuel L. Peter, Patrick Engeu Ogwang

Astragalus mongholicus Bunge and Panax notoginseng formula (A&P) improves renal mesangial cell damage in diabetic nephropathy by inhibiting the inflammatory response of infiltrated macrophages

Xiao Lin, Xiao-qin Lei, Jie-ke Yang, Jian Jia, Xia Zhong, Rui-zhi Tan, Li Wang

Arrabidaea chica chloroform extract modulates estrogen and androgen receptors on luminal breast cancer cells

Douglas C. Brandão, Paula M. A. P. Lima, Isabella C. Martins, Carina S. Cordeiro, Antonielle O. Cordeiro, Lara Vecchi, Joyce F. C. Guerra, Priscila C. Orsolin, Matheus C. Gazolla, Danilo S. Costa, Ademar A. da Silva Filho, Thaise G. Araújo

Effects of curcumin supplementation on vitamin D levels in women with premenstrual syndrome and dysmenorrhea: a randomized controlled study

  • Open Access
  • Research

Leyla Arabnezhad, Mahtab Mohammadifard, Ladan Rahmani, Zahra Majidi, Gordon A. Ferns, Afsane Bahrami

Leaf extract of Osbeckia octandra induces apoptosis in oral squamous cell carcinoma cells

  • Open Access
  • Research

Jue Young Kim, Jin Kim, B. M. Ratnayake Bandara, Wanninayake M. Tilakaratne, Dokyeong Kim

Bioinformatics screening the novel and promising targets of curcumin in hepatocellular carcinoma chemotherapy and prognosis

Tingting Yang, Yibiao Chen, Jiexuan Xu, Jinyuan Li, Hong Liu, Naihua Liu

Complementary and integrative medicine perspectives among veteran patients and VHA healthcare providers for the treatment of headache disorders: a qualitative study

Deena E. Kuruvilla, Hayley Lindsey, Amy S. Grinberg, Roberta E. Goldman, Samantha Riley, Sean Baird, Brenda T. Fenton, Jason J. Sico, Teresa M. Damush

Attenuation of carbohydrate metabolism and lipid profile by methanolic extract of Euphorbia helioscopia and improvement of beta cell function in a type 2 diabetic rat model

Imtiaz Mustafa, Haseeb Anwar, Shahzad Irfan, Humaira Muzaffar, Muhammad Umar Ijaz

Analysis of the therapeutic effect of Dimu Ningshen (TCM formula) on attention deficit hyperactivity disorder based on gut microbiota and serum metabolomics

Kairui Tang, Wenzhi Hao, Xiaowei Mo, Yueyue Chen, Xiaofang Guo, Liangliang He, Binghua Wang, Juxian Wang, Qingyu Ma, Lijuan Deng, Jiaxu Chen

Ononin ameliorates inflammation and cartilage degradation in rat chondrocytes with IL-1β-induced osteoarthritis by downregulating the MAPK and NF-κB pathways

Fang Xu, Liang-Jun Zhao, Ting Liao, Zhao-Cong Li, Lei-Lei Wang, Pan-Yu Lin, Rui Jiang, Qing-Jun Wei

HPLC-DAD phenolics analysis, α-glucosidase, α-amylase inhibitory, molecular docking and nutritional profiles of Persicaria hydropiper L.

  • Open Access
  • Research

Mater H. Mahnashi, Yahya S. Alqahtani, Bandar A. Alyami, Ali O. Alqarni, Sultan A. Alqahl, Farhat Ullah, Abdul Sadiq, Alam Zeb, Mehreen Ghufran, Alexey Kuraev, Asif Nawaz, Muhammad Ayaz

Extracts of Sida cordifolia contain polysaccharides possessing immunomodulatory activity and rosmarinic acid compounds with antibacterial activity

Haroon Iqbal, Claire L. Wright, Sue Jones, Goncalo Rosas da Silva, John McKillen, Brendan F. Gilmore, Owen Kavanagh, Brian D. Green

HyperCKemia associated with acupuncture: a case report and review of the literature

Xiaochan Tan, Wei Liu, Yuzheng Du, Xianggang Meng, Xuemin Shi

RNA-seq based transcriptome analysis of ethanol extract of saffron protective effect against corticosterone-induced PC12 cell injury

Xi Chen, Ting Yang, Congen Zhang, Zhijie Ma

In vitro and in vivo evaluations of antioxidative, anti-Alzheimer, antidiabetic and anticancer potentials of hydroponically and soil grown Lactuca sativa

  • Open Access
  • Research

Shahid Naseem, Hammad Ismail

Promotion of HepG2 cell apoptosis by Sedum emarginatum Migo and the mechanism of action

  • Open Access
  • Research

Qin Qiu, Lujuan Jiang, Hanshen Zhen, Fengyin Huang, Dandan Zhen, Meifang Ye, Xueyan Meng, Yuanyuan Liu, Xijun Qin

Effect of Cinnamaldehyde on C. albicans cell wall and (1,3)- β – D-glucans in vivo

Jie-Hua Deng, Xiao-Guang Zhang, Gang-Sheng Wang, Jing-Na Luo, Jia Wang, Xiao-Ming Qi, Yan-Ling Li

Network pharmacology and in vitro studies reveal the pharmacological effects and molecular mechanisms of Shenzhi Jiannao prescription against vascular dementia

Danfeng Tian, Qiang Gao, Ze Chang, Jingfeng Lin, Dayong Ma, Zhenyun Han

Krill oil supplementation reduces the growth of CT-26 orthotopic tumours in Balb/c mice

Abilasha Gayani Jayathilake, Elif Kadife, Nyanbol Kuol, Rodney Brain Luwor, Kulmira Nurgali, Xiao Qun Su

Interactions of selected cardiovascular active natural compounds with CXCR4 and CXCR7 receptors: a molecular docking, molecular dynamics, and pharmacokinetic/toxicity prediction study

Hussam Aly Sayed Murad, Thamer Mohammed Ahmed Alqurashi, Mostafa Aly Hussien

Exploring the total flavones of Abelmoschus manihot against IAV-induced lung inflammation by network pharmacology

Yanan Gao, Zihao Liang, Nianyin Lv, Jinjun Shan, Huihui Zhou, Junfeng Zhang, Liyun Shi

Stay mindfully active during the coronavirus pandemic: a feasibility study of mHealth-delivered mindfulness yoga program for people with Parkinson’s disease

Jojo Yan Yan Kwok, Jung Jae Lee, Edmond Pui Hang Choi, Pui Hing Chau, Man Auyeung

A flavonoid rich standardized extract of Glycyrrhiza glabra protects intestinal epithelial barrier function and regulates the tight-junction proteins expression

  • Open Access
  • Research

Sasi Kumar Murugan, Bharathi Bethapudi, Subramanian Raghunandhakumar, Divya Purusothaman, Muruganantham Nithyanantham, Deepak Mundkinajeddu, Muralidhar Srinivasaih Talkad

Origanum vulgare L. essential oil inhibits virulence patterns of Candida spp. and potentiates the effects of fluconazole and nystatin in vitro

Camila Cid-Chevecich, Andrea Müller-Sepúlveda, José Antonio Jara, Rodrigo López-Muñoz, Rocío Santander, Mauricio Budini, Alejandro Escobar, Raúl Quijada, Alfredo Criollo, Mario Díaz-Dosque, Alfredo Molina-Berríos

Thymol protects against 6-hydroxydopamine-induced neurotoxicity in in vivo and in vitro model of Parkinson’s disease via inhibiting oxidative stress

Saeideh Nourmohammadi, Sanaz Yousefi, Mahboubeh Manouchehrabadi, Mona Farhadi, Zahra Azizi, Anahita Torkaman-Boutorabi

Complementary medicine use in stroke survivors: a US nationally representative survey

Wiebke K. Kohl-Heckl, Anna K. Koch, Holger Cramer

Antibiofilm and anticancer activities of unripe and ripe Azadirachta indica (neem) seed extracts

  • Open Access
  • Research

Kartik Chandra Guchhait, Tuhin Manna, Manas Barai, Monalisha Karmakar, Sourav Kumar Nandi, Debarati Jana, Aditi Dey, Suman Panda, Priyanka Raul, Anuttam Patra, Rittwika Bhattacharya, Subhrangsu Chatterjee, Amiya Kumar Panda, Chandradipa Ghosh

Prevalence and predictive factors of complementary medicine use during the first wave of the COVID-19 pandemic of 2020 in the Netherlands

  • Open Access
  • Care
  • Research

Louise T. C. Mulder, Martine Busch, Agnete E. Kristoffersen, Johanna Hök Nordberg, Esther T. van der Werf

Efficacy and safety evaluation of black ginseng (Panax ginseng C.A. Mey.) extract (CJ EnerG): broad spectrum cytotoxic activity in human cancer cell lines and 28-day repeated oral toxicity study in Sprague-Dawley rats

  • Open Access
  • Research

Jin-Sung Park, Seung-Hyun Kim, Kang-Min Han, Yun-Soon Kim, Euna Kwon, Se-Hee Paek, Yong-Ki Seo, Jun-Won Yun, Byeong-Cheol Kang

Gastrodin promotes the regeneration of peripheral nerves by regulating miR-497/BDNF axis

Li Yongguang, Wang Xiaowei, Yan Huichao, Zhang Yanxiang

In vitro evaluation of the inhibition potential of echinacoside on human cytochrome P450 isozymes

Yujie Wu, Aiqing Qiao, Shu Lin, Lijia Chen

Antibacterial activities of plant leaf extracts against multi-antibiotic resistant Staphylococcus aureus associated with skin and soft tissue infections

P. A. Akinduti, V. Emoh-Robinson, H. F. Obamoh-Triumphant, Y. D. Obafemi, T. T. Banjo

Methodological quality of systematic reviews on Chinese herbal medicine: a methodological survey

  • Open Access
  • Research

Andy K. L. Cheung, Charlene H. L. Wong, Leonard Ho, Irene X. Y. Wu, Fiona Y. T. Ke, Vincent C. H. Chung

Cytotoxicity and anti-HIV activities of extracts of the twigs of Croton dichogamus Pax

Ermias Mergia Terefe, Faith Apolot Okalebo, Solomon Derese, Gaber El-Saber Batiha, Amal Youssef, Mohammed Alorabi, Joseph Muriuki

Analgesic, anti-inflammatory and acute oral toxicity profile of leaf and bark extracts of Albizia procera

Sangeetha Mani, Chamundeeswari Duraipandian, Saravana Babu Chidambaram

Evaluation of the antimalarial activity and toxicity of Mahanil-Tang-Thong formulation and its plant ingredients

Prapaporn Chaniad, Arisara Phuwajaroanpong, Tachpon Techarang, Natharinee Horata, Arnon Chukaew, Chuchard Punsawad

Extract of Corallodiscus flabellata attenuates renal fibrosis in SAMP8 mice via the Wnt/β-catenin/RAS signaling pathway

  • Open Access
  • Research

Bing Cao, Mengnan Zeng, Yanpo Si, Beibei Zhang, Yangyang Wang, Ruiqi Xu, Yanjie Huang, Weisheng Feng, Xiaoke Zheng

Screening the components of Saussurea involucrata for novel targets for the treatment of NSCLC using network pharmacology

  • Open Access
  • NSCLC
  • Research

Dongdong Zhang, Tieying Zhang, Yao Zhang, Zhongqing Li, He Li, Yueyang Zhang, Chenggong Liu, Zichao Han, Jin Li, Jianbo Zhu

An advanced network pharmacology study to explore the novel molecular mechanism of Compound Kushen Injection for treating hepatocellular carcinoma by bioinformatics and experimental verification

Shan Lu, Ziqi Meng, Yingying Tan, Chao Wu, Zhihong Huang, Jiaqi Huang, Changgeng Fu, Antony Stalin, Siyu Guo, Xinkui Liu, Leiming You, Xiaojiaoyang Li, Jingyuan Zhang, Wei Zhou, Xiaomeng Zhang, Miaomiao Wang, Jiarui Wu

Anti-inflammatory effects of flavonoids and phenylethanoid glycosides from Hosta plantaginea flowers in LPS-stimulated RAW 264.7 macrophages through inhibition of the NF-κB signaling pathway

  • Open Access
  • Research

Li Yang, Junwei He

Network pharmacology-based predictions of active components and pharmacological mechanisms of Artemisia annua L. for the treatment of the novel Corona virus disease 2019 (COVID-19)

Yexiao Tang, Xiaobo Li, Yueming Yuan, Hongying Zhang, Yuanyuan Zou, Zhiyong Xu, Qin Xu, Jianping Song, Changsheng Deng, Qi Wang

Network pharmacology analysis reveals neuroprotection of Gynostemma pentaphyllum (Thunb.) Makino in Alzheimer’ disease

Jiahao Wang, Jiamiao Shi, Ning Jia, Qinru Sun

Alternative medicine: therapeutic effects on gastric original signet ring carcinoma via ascorbate and combination with sodium alpha lipoate

  • Open Access
  • Research

Weiyu Chen, Lingyun Xu, Edwin Chang, Gayatri Gowrishankar, Katherine W. Ferrara, Sanjiv Sam Gambhir

The effect of barberry (Berberis integerrima) on lipid profile and systemic inflammation in subjects with cardiovascular risk factors: a randomized controlled trial

  • Open Access
  • Research

Hadi Emamat, Ali Zahedmehr, Sanaz Asadian, Javad Nasrollahzadeh

Multimodal stress reduction and lifestyle modification program for patients with ulcerative colitis: a qualitative study

Christoph Schlee, Christine Uecker, Nina Bauer, Anna K. Koch, Jost Langhorst

Gynura segetum-induced liver injury leading to acute liver failure: a case report and literature review

Zilong Zhang, Haibo Zou, Zonglin Dai, Jin Shang, Shining Sure, Chunyou Lai, Ying Shi, Qinyan Yang, Guangming Xiang, Yutong Yao, Tianhang Feng, Deyuan Zhong, Xiaolun Huang

GlucoMedix®, an extract of Stevia rebaudiana and Uncaria tomentosa, reduces hyperglycemia, hyperlipidemia, and hypertension in rat models without toxicity: a treatment for metabolic syndrome

León F. Villegas Vílchez, Julio Hidalgo Ascencios, Thomas P. Dooley

Icariin regulates stem cell migration for endogenous repair of intervertebral disc degeneration by increasing the expression of chemotactic cytokines

Zhaofei Zhang, Fengwei Qin, Yonghui Feng, Sineng Zhang, Chunliang Xie, He Huang, Chaohui Sang, Shaoyu Hu, Feng Jiao, Jie Jiang, Yi Qin

Artemisia argyi extract alleviates inflammation in a DSS-induced colitis mouse model and enhances immunomodulatory effects in lymphoid tissues

Ji Min Shin, Yang-Ju Son, In Jin Ha, Saruul Erdenebileg, Da Seul Jung, Dae-geun Song, Young Sik Kim, Sang Min Kim, Chu Won Nho

Antimicrobial potential of four mica drugs and their chemical and mineralogical properties

  • Open Access
  • Research

Apsara Wijenayake, Charmalie Abayasekara, Amarasooriya Pitawala, B. M. Ratnayake Bandara

The efficiency of natural wound healing and bacterial biofilm inhibition of Aloe vera and Sodium Chloride toothpaste preparation

La-ongthong Vajrabhaya, Suwanna Korsuwannawong, Nisarat Ruangsawasdi, Chareerut Phruksaniyom, Ratchaporn Srichan

‘Joining a group was inspiring’: a qualitative study of service users’ experiences of yoga on social prescription

  • Open Access
  • Research

Anna Cheshire, Rebecca Richards, Tina Cartwright

Anticancer potential of Phoenix dactylifera L. seed extract in human cancer cells and pro-apoptotic effects mediated through caspase-3 dependent pathway in human breast cancer MDA-MB-231 cells: an in vitro and in silico investigation

Mohsin Ali Khan, Romila Singh, Sahabjada Siddiqui, Imran Ahmad, Rumana Ahmad, Shivbrat Upadhyay, Md. Abul Barkat, Ahmed Mahmoud Abdelhaleem Ali, Qamar Zia, Aditi Srivastava, Anchal Trivedi, Ishrat Husain, Anand Narain Srivastava, Durga Prasad Mishra

Evaluation of anticandidal activities and phytochemical examination of extracts prepared from Vitex agnus-castus: a possible alternative in treating candidiasis infections

Fatima O. Al-Otibi, Ghaida I. Alrumaizan, Raedah I. Alharbi

Traditional and complementary medicine use among cancer patients in Nepal: a cross-sectional survey

  • Open Access
  • Research

Soo Jeung Choi, Sangita Karki Kunwor, Hyea Bin Im, Jung Hye Hwang, Dain Choi, Dongwoon Han

16S rRNA sequencing-based evaluation of the protective effects of Hua-Zhuo-Jie-Du on rats with chronic atrophic gastritis

Pingping Zhou, Tianxiao Yang, Miaochan Xu, Yuejia Zhao, Pengpeng Shen, Yangang Wang

In vivo assessment of the antimalarial activity and acute oral toxicity of an ethanolic seed extract of Spondias pinnata (L.f.) Kurz

Prapaporn Chaniad, Arisara Phuwajaroanpong, Walaiporn Plirat, Tachpon Techarang, Arnon Chukaew, Chuchard Punsawad

Chrysoeriol suppresses hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes and inhibits JAK2/STAT3 signaling

Jia-Ying Wu, Ying-Jie Chen, Xiu-Qiong Fu, Jun-Kui Li, Ji-Yao Chou, Cheng-Le Yin, Jing-Xuan Bai, Ying Wu, Xiao-Qi Wang, Amy Sze-man Li, Lut Yi Wong, Zhi-Ling Yu

Antimicrobial activity, in vitro anticancer effect (MCF-7 breast cancer cell line), antiangiogenic and immunomodulatory potentials of Populus nigra L. buds extract

Brigitta Kis, Ioana Zinuca Pavel, Stefana Avram, Elena Alina Moaca, Martina Herrero San Juan, Anja Schwiebs, Heinfried H. Radeke, Delia Muntean, Zorita Diaconeasa, Daliana Minda, Camelia Oprean, Florina Bojin, Cristina Adriana Dehelean, Codruta Soica, Corina Danciu

Fruitflow inhibits platelet function by suppressing Akt/GSK3β, Syk/PLCγ2 and p38 MAPK phosphorylation in collagen-stimulated platelets

  • Open Access
  • Research article

Huilian Chen, Shenghao Zhang, Hui Wang, Li Bao, Wei Wu, Ruomei Qi

Protective effect of Sophora pachycarpa seed extract on carbon tetrachloride-induced toxicity in rats

  • Open Access
  • Research

Hamed Aramjoo, Pouria Mohammadparast-Tabas, Tahereh Farkhondeh, Mahmoud Zardast, Marzieh Makhdoumi, Saeed Samarghandian, Zahra Kiani

Electroacupuncture for treating cancer-related insomnia: a multicenter, assessor-blinded, randomized controlled, pilot clinical trial

Boram Lee, Bo-Kyung Kim, Mikyung Kim, Ae-Ran Kim, Hyo-Ju Park, O-Jin Kwon, Jun-Hwan Lee, Joo-Hee Kim

Antimicrobial activity of Bacillus sp. isolated strains of wild honey

Somayeh Hallaj-Nezhadi, Rasoul Hamdipour, Mohamad Shahrvirani, Roya Zare tin, Florence Chapeland-leclerc, Gwenael Ruprich-Robert, Solmaz Esnaashari, Babak Elyasi Far, Azita Dilmaghani

Anti-glycation properties of Illicium verum Hook. f. fruit in-vitro and in a diabetic rat model

  • Open Access
  • Research

Hafiz Nadeem Khan, Saima Rasheed, M. Iqbal Choudhary, Nessar Ahmed, Abdu Adem

Hydro-ethanol extract of Holarrhena floribunda stem bark exhibits anti-anaphylactic and anti-oedematogenic effects in murine models of acute inflammation

Stephen Antwi, Daniel Oduro-Mensah, David Darko Obiri, Newman Osafo, Aaron Opoku Antwi, Helena Owusu Ansah, Augustine Ocloo, Laud K. N.-A. Okine

Transcranial photobiomodulation add-on therapy to valproic acid for pentylenetetrazole-induced seizures in peripubertal rats

Chung-Min Tsai, Shwu-Fen Chang, Hsi Chang

Different effects on the tonus of colon and ileum isolated from mouse by resin glycoside (pharbitin) of Pharbitidis Semen

Jian-Rong Zhou, Naofumi Tokutomi, Yuusuke Satou, Shin Yasuda, Hideki Kinoshita, Toshihiro Nohara, Kazumi Yokomizo, Masateru Ono

Aqueous Thunbergia laurifolia leaf extract alleviates paraquat-induced lung injury in rats by inhibiting oxidative stress and inflammation

Sarawoot Palipoch, Chuchard Punsawad, Phanit Koomhin, Prasit Na-Ek, Wasinee Poonsawat, Rungruedi Kimseng, Potiga Chotipong, Kingkan Bunluepuech, Gorawit Yusakul, Prasit Suwannalert

Larrea divaricata: anti-inflammatory and antioxidant effects on macrophages and low density lipoproteins

  • Open Access
  • Research

Ignacio Peralta, Carla Marrassini, Malen Saint Martin, Laura Cogoi, María Rosario Alonso, Alejandro Gugliucci, Claudia Anesini

Polyphenols in Ilex latifolia Thunb. inhibit human lung cancer cell line A549 by regulation of the PI3K-Akt signaling pathway

Jing Chen, Yesheng Du, Yanyan Long, Dan Tao, Mengyu Hu, Yong Jiang, Yue Wan, Dingyi Yang

The process of learning the autogenic training relaxation technique and its benefits on the wellness of people living with HIV

Maria Pilar Ramirez Garcia, Jérôme Leclerc-Loiselle, José Côté, Marie-Josée Brouillette, Réjean Thomas

Effects of auricular acupressure on chemotherapy-induced nausea and vomiting in breast cancer patients: a preliminary randomized controlled trial

  • Open Access
  • Nausea
  • Research article

Jing-Yu Tan, Alex Molassiotis, Lorna K. P. Suen, Jian Liu, Tao Wang, Hui-Rong Huang

Retraction Note: A candidate Chinese medicine preparation-Fructus Viticis Total Flavonoids inhibits stem-like characteristics of lung cancer stem-like cells

  • Open Access
  • Retraction Note

Xiaocheng Cao, Hui Zou, Jianguo Cao, Yinghong Cui, Shuwen Sun, Kaiqun Ren, Zhenwei Song, Duo Li, Meifang Quan

Metabolomic strategies and biochemical analysis of the effect of processed Rehmanniae radix extract on a blood-deficient rat model

Yang-yang Wang, Ning Zhou, Zeng-fu Shan, Ying-ying Ke, Zhen Liu, Zhen-hui Liu, Wei-sheng Feng, Xiao-ke Zheng

In vitro antibacterial and cytotoxic effects of Euphorbia grandicornis Blanc chemical constituents

Douglas Kemboi, Moses K. Langat, Xavier Siwe-Noundou, Rui W. M. Krause, Michelle Louise Isaacs, Vuyelwa Jacqueline Tembu

The prevalence of using complementary and alternative medicine products among patients with pressure ulcer

  • Open Access
  • Research

Niloofar Karimianfard, Azita Jaberi

Huaier attenuates the adverse effects of pyroptosis by regulating the methylation of rat mesangial cells: an in vitro study

  • Open Access
  • Research

Wenjia Geng, Can Tu, Dahao Chen, Zhaoyu Lu, Wei Mao, Hanyu Zhu

Bacterial diversity in the intestinal mucosa of heart failure rats treated with Sini Decoction

Zhenyu Zhao, Jiahao Liu, Yanzhi Hu, Xining Zhang, Liqin Cao, Zhenhua Dong, Lin Li, Zhixi Hu

The changing clinical landscape in acupuncture for women’s health: a cross-sectional online survey in New Zealand and Australia

Sandro Graca, Debra Betts, Kate Roberts, Caroline A. Smith, Mike Armour

Paravertebral abscess and bloodstream infection caused by Burkholderia pseudomallei after acupuncture: a case report

Lingyan Xiao, Tong Zhou, Jun Chen, Yanqing Hu, Yishan Zheng

Ninjinyoeito ameliorated cigarette smoke extract-induced apoptosis and inflammation through JNK signaling inhibition in human lung fibroblasts

Kenta Murata, Nina Fujita, Ryuji Takahashi

Complementary and alternative medicine modalities used to treat adverse effects of anti-cancer treatment among children and young adults: a systematic review and meta-analysis of randomized controlled trials

Dana C. Mora, Grete Overvåg, Miek C. Jong, Agnete E. Kristoffersen, Debbie C. Stavleu, Jianping Liu, Trine Stub

Hesperidin identified from Citrus extracts potently inhibits HCV genotype 3a NS3 protease

Mahim Khan, Waqar Rauf, Fazal-e- Habib, Moazur Rahman, Shoaib Iqbal, Aamir Shehzad, Mazhar Iqbal

Parthenolide leads to proteomic differences in thyroid cancer cells and promotes apoptosis

Meng Cui, Zhe Wang, Le-Tian Huang, Jia-He Wang

Hinokiflavone induces apoptosis, cell cycle arrest and autophagy in chronic myeloid leukemia cells through MAPK/NF-κB signaling pathway

Xiang Qin, Xi Chen, Ling Guo, Jing Liu, You Yang, Yan Zeng, Cheng Li, Wenjun Liu, Wenzhe Ma

Inhibitory effects of Syzygium jambos extract on biomarkers of endothelial cell activation

Yaritza Inostroza-Nieves, Shirley Valentin-Berrios, Christopher Vega, Gregory N. Prado, Claribel Luciano-Montalvo, José R. Romero, Alicia Rivera

Correction to: Alleviation of 4-nitroquinoline 1-oxide induced oxidative stress by Oroxylum indicum (L.) leaf extract in albino Wistar rats

  • Open Access
  • Correction

Shalini Mohan, Kalaivani Thiagarajan, Balaji Sundaramoorthy, Vivek Gurung, Manas Barpande, Shilpi Agrawal, Rajasekaran Chandrasekaran

Uncovering the potential mechanism of Xue Fu Zhu Yu Decoction in the treatment of intracerebral hemorrhage

Dao-jin Xue, Zheng Zhen, Ke-xin Wang, Jia-lin Zhao, Yao Gao, Yu-peng Chen, You-bi Shen, Zi-zhuang Peng, Dao-gang Guan, Tao Huang

Operational definition of complementary, alternative, and integrative medicine derived from a systematic search

  • Open Access
  • Research article

Jeremy Y. Ng, Tushar Dhawan, Ekaterina Dogadova, Zhala Taghi-Zada, Alexandra Vacca, L. Susan Wieland, David Moher

Tracking discussions of complementary, alternative, and integrative medicine in the context of the COVID-19 pandemic: a month-by-month sentiment analysis of Twitter data

Jeremy Y. Ng, Wael Abdelkader, Cynthia Lokker

Interest and need for continuing medical education in pediatric complementary and integrative medicine: a cross-sectional survey from Switzerland

Benedikt M. Huber, Pierre-Yves Rodondi

Primary health care case management through the lens of complexity: an exploratory study of naturopathic practice using complexity science principles

  • Open Access
  • Care
  • Research

Kim D. Graham, Amie Steel, Jon Wardle

Clausena Harmandiana root extract attenuated cognitive impairments via reducing amyloid accumulation and neuroinflammation in Aβ1-42-induced rats

Nutchareeporn Nillert, Chantana Boonyarat, Jariya Umka Welbat, Komsun Bunreungthong, Ploenthip Puthongking, Wanassanun Pannangrong

Prophylactic effect of topical (slow-release) and systemic curcumin nano-niosome antioxidant on oral cancer in rat

Behzad Fazli, Soussan Irani, Hassan Bardania, Mahdieh-Sadat Moosavi, Bita Rohani

Tanshinone I attenuates fibrosis in fibrotic kidneys through down-regulation of inhibin beta-A

Ming Wu, Feng Yang, Di Huang, Chaoyang Ye

Correction to: The prevalence of using complementary and alternative medicine products among patients with pressure ulcer

  • Open Access
  • Correction

Niloofar Karimianfard, Azita Jaberi

Proangiogenesis effects of compound danshen dripping pills in zebrafish

Yang-Xi Hu, Hong-Min You, Chang-Zhen Ren, Bo-Wen Hu, Lu-Jun Zhang, Yan-Da Zhang, Zhi-Qing He, Ru Ding, Zhi-Fu Guo, Chun Liang

Predictors of the intention to use traditional Chinese medicine (TCM) using extended theory of planned behavior: a cross-sectional study among TCM users in Hong Kong

  • Open Access
  • Research

Tommy K. C. Ng, Man Fung Lo, Ben Y. F. Fong, Hilary H. L. Yee

Anti-SARS-CoV-2 potential of Cissampelos pareira L. identified by connectivity map-based analysis and in vitro studies

Madiha Haider, Vivek Anand, M. Ghalib Enayathullah, Yash Parekh, Sushma Ram, Surekha Kumari, Anmol, Gayatri Panda, Manjari Shukla, Dhwani Dholakia, Arjun Ray, Sudipta Bhattacharyya, Upendra Sharma, Kiran Kumar Bokara, Bhavana Prasher, Mitali Mukerji

Trans-cinnamaldehyde protects against phenylephrine-induced cardiomyocyte hypertrophy through the CaMKII/ERK pathway

  • Open Access
  • Research

Dongdong Qian, Jing Tian, Sining Wang, Xiaoli Shan, Pei Zhao, Huihua Chen, Ming Xu, Wei Guo, Chen Zhang, Rong Lu

Diosmin mitigates high glucose-induced endoplasmic reticulum stress through PI3K/AKT pathway in HK-2 cells

Jiuhong Deng, Chao Zheng, Zhou Hua, Haideng Ci, Guiying Wang, Lijing Chen

Lipotropic activities of aqueous extract of Vernonia guineensis Benth. in Wistar rats fed high fat diet

Leila Sandra Nnanga, Bruno Dupon Akamba Ambamba, Fils Armand Ella, Damaris Enyegue Mandob, Judith Laure Ngondi

A survey of multidisciplinary healthcare providers utilizing the KNOWintegrativeoncology.org educational platform

  • Open Access
  • Care
  • Research

Jen Green, Heather Wright, Dugald Seely, Mark Legacy, Maureen Anderson, Hallie Armstrong, Casey Martell, Sarah Soles, Lynda G. Balneaves

Anti-inflammatory effects of lavender and eucalyptus essential oils on the in vitro cell culture model of bladder pain syndrome using T24 cells

Adrienn Horváth, Edina Pandur, Katalin Sipos, Giuseppe Micalizzi, Luigi Mondello, Andrea Böszörményi, Péter Birinyi, Györgyi Horváth

Scutellaria barbata D.Don (SBD) extracts suppressed tumor growth, metastasis and angiogenesis in Prostate cancer via PI3K/Akt pathway

Dongya Sheng, Bei Zhao, Wenjing Zhu, Tiantian Wang, Yu Peng

Network pharmacology combined with molecular docking to explore the potential mechanisms for the antioxidant activity of Rheum tanguticum seeds

Lingling Wang, Feng Xiong, Shuo Zhao, Yang Yang, Guoying Zhou

Formulation of Neem oil-loaded solid lipid nanoparticles and evaluation of its anti-Toxoplasma activity

Sara Nemati, Hanieh Mohammad Rahimi, Zahra Hesari, Meysam Sharifdini, Nooshin Jalilzadeh Aghdam, Hamed Mirjalali, Mohammad Reza Zali

Ursolic acid-enriched kudingcha extract enhances the antitumor activity of bacteria-mediated cancer immunotherapy

Haixia Xu, Linghua Piao, Xiande Liu, Sheng-nan Jiang

Rauwolfia vomitoria extract suppresses benign prostatic hyperplasia by inducing autophagic apoptosis through endoplasmic reticulum stress

Guifang Huang, Xiao He, Zesheng Xue, Yiming Long, Jiakuan Liu, Jinming Cai, Pengfei Tang, Bangmin Han, Bing Shen, Ruimin Huang, Jun Yan

Primary care patients’ perspectives on the use of non-pharmacological home remedies in Geneva: a cross-sectional study

  • Open Access
  • Care
  • Research

Neria E. Winkler, Paul Sebo, Dagmar M. Haller, Hubert Maisonneuve

Meditative practices, stress and sleep among students studying complementary and integrative health: a cross-sectional analysis

  • Open Access
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Adam Sadowski, Ryan S. Wexler, Douglas Hanes, Lita Buttolph, Tediana Torrens, Jillian Moehle, Hadil Sarrar, Joanna Harnett, David T. Zava, Ryan Bradley

A qualitative investigation of the perceptions of complementary and alternative medicine among adults in Hawaiʻi

  • Open Access
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Brittany R. Odegard, Mollie R. Ferguson, Farah Naja, Jennifer Ayoub, Jinan Banna

Jianpi Qinghua Fomula alleviates insulin resistance via restraining of MAPK pathway to suppress inflammation of the small intestine in DIO mice

Yahua Liu, Xu Han, Mengjie Cai, Shenyi Jin, Zihui Yan, Hao Lu, Qingguang Chen

Wild Egyptian medicinal plants show in vitro and in vivo cytotoxicity and antimalarial activities

Ahmed M. Abdou, Abdel-latif S. Seddek, Noha Abdelmageed, Mohamed O. Badry, Yoshifumi Nishikawa

Evidence for anti-inflammatory effects and modulation of neurotransmitter metabolism by Salvia officinalis L.

  • Open Access
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Gemma Margetts, Sotirios Kleidonas, Nawel S. Zaibi, Mohamed S. Zaibi, Kieron D. Edwards

System-level investigation of anti-obesity effects and the potential pathways of Cordyceps militaris in ovariectomized rats

Dongyeop Jang, Eunjoo Lee, Sullim Lee, Yongsam Kwon, Ki Sung Kang, Chang-Eop Kim, Daeyoung Kim

Qiangjing tablets repair of blood-testis barrier dysfunction in rats via regulating oxidative stress and p38 MAPK pathway

  • Open Access
  • Research

Junjun Li, Yaodong You, Peihai Zhang, Xiaopeng Huang, Liang Dong, Fang Yang, Xujun Yu, Degui Chang

Evaluation of anti-proliferative activity of Eryngium caucasicum on melanoma cancer cells

Haleh Forouhandeh, Zahra Rezaei Param, Ommoleila Molavi, Parina Asgharian, Vahideh Tarhriz

Cytotoxic activity of non-specific lipid transfer protein (nsLTP1) from Ajwain (Trachyspermum ammi) seeds

  • Open Access
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Saud O. Alshammari, Taibah Aldakhil, Qamar A. Alshammari, David Salehi, Aftab Ahmed

Correction: Lactobacillus plantarum PS128 prevents cognitive dysfunction in alzheimer’s disease mice by modulating propionic acid levels, glycogen synthase kinase 3 beta activity, and gliosis

Hei-Jen Huang, Jie-Ling Chen, Jian-Fu Liao, Yu-Hsin Chen, Min-Wei Chieu, Ya-Yun Ke, Chih-Chieh Hsu, Ying-Chieh Tsai, Hsiu Mei Hsieh-Li

The effect of cancer on traditional, complementary and alternative medicine utilization in Korea: a fixed effect analysis using Korea Health Panel data

  • Open Access
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Dongsu Kim, Soo-Hyun Sung, Seungwon Shin, Minjung Park

Shared meditation involving cancer patients, health professionals and third persons is relevant and improves well-being: IMPLIC pilot study

Virginie Prevost, Sophie Lefevre-Arbogast, Alexandra Leconte, Claire Delorme, Sandrine Benoit, Titi Tran, Bénédicte Clarisse

Standardization of the ethanolic extract of Crinum latifolium leaves by two bioactive markers with antiproliferative activity against TGF-β-promoted prostate stromal cells (WPMY-1)

Wisuwat Thongphichai, Tamonwan Uttarawichien, Pithi Chanvorachote, Supaporn Pitiporn, Todsaphol Charoen-ame, Pakakrong Kwankhao, Pasarapa Towiwat, Suchada Sukrong

Nanoliposomes containing limonene and limonene-rich essential oils as novel larvicides against malaria and filariasis mosquito vectors

Alireza Sanei-Dehkordi, Mohammad Djaefar Moemenbellah-Fard, Mostafa Saffari, Elham Zarenezhad, Mahmoud Osanloo

The potential effects and mechanisms of hispidulin in the treatment of diabetic retinopathy based on network pharmacology

Yao Chen, Jiaojiao Sun, Zhiyun Zhang, Xiaotong Liu, Qiaozhi Wang, Yang Yu

Chemical composition, antibiofilm, cytotoxic, and anti-acetylcholinesterase activities of Myrtus communis L. leaves essential oil

Lucia Caputo, Francesca Capozzolo, Giuseppe Amato, Vincenzo De Feo, Florinda Fratianni, Giovanni Vivenzio, Filomena Nazzaro

Anti-inflammatory and anti-nociceptive effects of Cinnamon and Clove essential oils nanogels: an in vivo study

  • Open Access
  • Edema
  • Research

Fariba Esmaeili, Masoumeh Zahmatkeshan, Yaser Yousefpoor, Hiva Alipanah, Ehsan Safari, Mahmoud Osanloo

Photoprotective effects of Sargassum thunbergii on ultraviolet B-induced mouse L929 fibroblasts and zebrafish

  • Open Access
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Bei Chen, Honghong Chen, Haidong Qu, Kun Qiao, Min Xu, Jingna Wu, Yongchang Su, Yan Shi, Zhiyu Liu, Qin Wang

Naringenin and cryptotanshinone shift the immune response towards Th1 and modulate T regulatory cells via JAK2/STAT3 pathway in breast cancer

Shokoofe Noori, Mitra Nourbakhsh, Hossein Imani, Niloofar Deravi, Niloufar Salehi, Zohreh Abdolvahabi

A cross-sectional study of herbal medicine use and contributing factors among pregnant women on antenatal care follow-up at Dessie Referral Hospital, Northeast Ethiopia

  • Open Access
  • Care
  • Research article

Yaschilal Muche Belayneh, Tewodros Yoseph, Solomon Ahmed

Gao-Zi-Yao improves learning and memory function in old spontaneous hypertensive rats

  • Open Access
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Meng-Xiao Han, Wen-Yi Jiang, Yan Jiang, Lin-Hui Wang, Rong Xue, Guo-Xing Zhang, Jing-Wei Chen

Use of massage therapy by mid-aged and older Australian women

Suzy Ladanyi, Jon Adams, David Sibbritt

The effect of gum Arabic supplementation on cathelicidin expression in monocyte derived macrophages in mice

  • Open Access
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Nagat Siednamohammeddeen, Rehab Badi, Tahane Mohammeddeen, Khalid Enan, AmalSaeed

Exploring the mechanism and experimental verification of puerarin in the treatment of endometrial carcinoma based on network pharmacology and bioinformatics analysis

Zhiheng Lin, Xiaohui Sui, Wenjian Jiao, Ying Wang, Junde Zhao

Exploring the comorbidity mechanisms between asthma and idiopathic pulmonary fibrosis and the pharmacological mechanisms of Bu-Shen-Yi-Qi decoction therapy via network pharmacology

Yuanyuan Zhong, Lingli Hu, Wenjing Chen, Bin Wang, Jing Sun, Jingcheng Dong

Network pharmacology and in vivo experiments reveal the pharmacological effects and molecular mechanisms of Simiao Powder in prevention and treatment for gout

  • Open Access
  • Gout
  • Research

Huachong Xu, Jialin Wu, Shiqi Wang, Lu Xu, Pei Liu, Yucong Shi, Sizhi Wu, Li Deng, Xiaoyin Chen

Correction: The potential effects and mechanisms of hispidulin in the treatment of diabetic retinopathy based on network pharmacology

Yao Chen, Jiaojiao Sun, Zhiyun Zhang, Xiaotong Liu, Qiaozhi Wang, Yang Yu

Phytochemistry, anti-diabetic and antioxidant potentials of Allium consanguineum Kunth

  • Open Access
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Mater H. Mahnashi, Yahya S. Alqahtani, Ali O. Alqarni, Bandar A. Alyami, Omaish S. Alqahtani, Muhammad Saeed Jan, Fida Hussain, Zia Ul Islam, Farhat Ullah, Muhammad Ayaz, Muhammad Abbas, Umer Rashid, Abdul Sadiq

Exploring patient experiences and acceptability of group vs. individual acupuncture for Cancer-related pain: a qualitative study

Devesh Oberoi, Erica N. Reed, Katherine-Ann Piedalue, Jessa Landmann, Linda E. Carlson

Menthol carbonates as potent antiparasitic agents: synthesis and in vitro studies along with computer-aided approaches

  • Open Access
  • Research

Camila M. Clemente, Sara M. Robledo, Soledad Ravetti

The protective effects of hyperoside on Ang II-mediated apoptosis of bEnd.3 cells and injury of blood-brain barrier model in vitro

Yu Yan Xie, Yun Wei Lu, Gu Ran Yu

RETRACTED ARTICLE: Suppression of NF-κB signaling by ECN in an arthritic model of inflammation

Amna Khan, Li Zhang, Chang Hu Li, Ashraf Ullah Khan, Bushra Shal, Adnan Khan, Sajjad Ahmad, Fakhar ud Din, Zia ur rehman, Feng Wang, Salman Khan

In vitro anti-HIV and cytotoxic effects of pure compounds isolated from Croton macrostachyus Hochst. Ex Delile

Ermias Mergia Terefe, Faith A. Okalebo, Solomon Derese, Moses K. Langat, Eduard Mas-Claret, Nada H. Aljarba, Saad Alkahtani, Gaber El-Saber Batiha, Arabinda Ghosh, Eman A. El-Masry, Joseph Muriuki

Investigation into the protective effects of hypaconitine and glycyrrhetinic acid against chronic heart failure of the rats

Liqin Wang, Haiming Deng, Tengyu Wang, Yun Qiao, Jianbing Zhu, Mingfeng Xiong

Developing and implementing a self-monitoring toolkit for a coordinated multinational randomized acupuncture trial

Sylvia Baedorf Kassis, Weidong Lu, Sarah A. White, Im Hee Shin, Sung Hwan Park, Young Ju Jeong, Chang Yao, Jennifer Ligibel, Barbara E. Bierer

Factors influencing use of conventional and traditional Korean medicine-based health services: a nationwide cross-sectional study

  • Open Access
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Yui Sasaki, Jeong-Su Park, Sunju Park, Chunhoo Cheon, Yong-Cheol Shin, Seong-Gyu Ko, Bo-Hyoung Jang

Verification of the folkloric and anecdotal antidiabetic effects of Hypoxis hemerocallidea (Fisch., C.A. Mey. & Avé-Lall) and isolated, β-sitosterol using early-stage type II spontaneous diabetic mutant BKS-Leprdb mice

  • Open Access
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N. M. Mkolo, O. O. Olaokun, P. H. King, I. Janse van Rensburg, J. N. Eloff, V. Naidoo

Forsythiaside A improves Influenza A virus infection through TLR7 signaling pathway in the lungs of mice

Xiao Zheng, Ziqi Chen, Shanshan Shi, Huijun Yan, Junmei Zhou, Lifang Jiang, Hongli Wang, Guanghui Hou, Zhenyou Jiang

Concurrent alteration in inflammatory biomarker gene expression and oxidative stress: how aerobic training and vitamin D improve T2DM

Rastegar Hoseini, Hiwa Ahmed Rahim, Jalal Khdhr Ahmed

Ginsenoside Rg-1 prevents elevated cytosolic Ca2+ via store-operated Ca2+ entry in high-glucose–stimulated vascular endothelial and smooth muscle cells

  • Open Access
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A Young Han, Su Min Ha, You Kyoung Shin, Geun Hee Seol

Wenyang Huazhuo Tongluo formula alleviates pulmonary vascular injury and downregulates HIF-1α in bleomycin-induced systemic sclerosis mouse model

Kai Li, Qian Wang, Qin Lv, Kelei Guo, Li Han, Peipei Duan, Yongzheng Deng, Hua Bian

Probiotics and their beneficial effects on alcohol-induced liver injury in a rat model: the role of fecal microbiota

Maneerat Chayanupatkul, Kanjana Somanawat, Natthaya Chuaypen, Naruemon Klaikeaw, Natcha Wanpiyarat, Prasong Siriviriyakul, Somying Tumwasorn, Duangporn Werawatganon

Anti-tumor and antioxidant activity of kaempferol-3-O-alpha-L-rhamnoside (Afzelin) isolated from Pithecellobium dulce leaves

  • Open Access
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Masuma Akter, Mst. Shahnaj Parvin, Md. Mahadi Hasan, Md. Aziz Abdur Rahman, Md. Ekramul Islam

Ellagic acid effects on testis, sex hormones, oxidative stress, and apoptosis in the relative sterility rat model following busulfan administration

Amirabbas Rostami, Sina Vakili, Farhad Koohpeyma, Bahia Namavar Jahromi, Ziba Afshari Aghajari, Fatemeh Mahmoudikohani, Forough Saki, Marzieh Mahmoodi, Khojaste Rahimi Jaberi, Ahmad Movahedpour, Majid Jafari Khorchani, Saam Noroozi

Complementary medicine in psychology practice: an analysis of Australian psychology guidelines and a comparison with other psychology associations from English speaking countries

  • Open Access
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Carrie Thomson-Casey, Jon Adams, Erica McIntyre

Fermented Mentha arvensis administration provides neuroprotection against transient global cerebral ischemia in gerbils and SH-SY5Y cells via downregulation of the MAPK signaling pathway

Md Sadikul Islam, Ha-Young Shin, Yeo-Jin Yoo, Eui-Yong Lee, Ryunhee Kim, Young-Jin Jang, Md Rashedunnabi Akanda, Hyun-Jin Tae, In-Shik Kim, Dongchoon Ahn, Byung-Yong Park

Chemical composition, anticancer and antibacterial activity of Nepeta mahanensis essential oil

  • Open Access
  • Research

Mahla Amirzadeh, Sara Soltanian, Neda Mohamadi

Anti-melanogenesis effect from Wampee fruit pectin via α-MSH/TRY pathway in A375 cells

  • Open Access
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Weiyu Fu, Xuehua Liao, Qian Zhang, Yuzhen Zhu, Si Mei, Qian Li, Xin Zhou, Xiaojun Li, Hui Luo, Hua Ye, Kefeng Wu

Evaluation of the effectiveness of the standard traditional Korean medicine-based health promotion program for disadvantaged children in South Korea

  • Open Access
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Eunhye Hyun, Jiseon Ryu, Kibong Kim, Sangjae Lee, Seungtae Kim, Byungmook Lim

Luteolin alleviates inflammation and autophagy of hippocampus induced by cerebral ischemia/reperfusion by activating PPAR gamma in rats

Lu Li, Guanghua Pan, Rong Fan, Dalei Li, Lei Guo, Lili Ma, Hui Liang, Jiaoxue Qiu

Isolated compounds from Dracaena angustifolia Roxb and acarbose synergistically/additively inhibit α-glucosidase and α-amylase: an in vitro study

Jiling Yi, Ting Zhao, Yuanlin Zhang, Yanxing Tan, Xiao Han, Yulin Tang, Guangying Chen

Cytotoxicity, acute and sub-chronic toxicities of the fruit extract of Tetrapleura tetraptera (Schumm. & Thonn.) Taub. (Fabaceae)

Idrios N. Bonsou, Armelle T. Mbaveng, Gaëlle S. Nguenang, Godloves F. Chi, Victor Kuete, Thomas Efferth

Reversal of cisplatin triggered neurotoxicity by Acacia hydaspica ethyl acetate fraction via regulating brain acetylcholinesterase activity, DNA damage, and pro-inflammatory cytokines in the rodent model

  • Open Access
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Tayyaba Afsar, Suhail Razak, Ali Almajwal

Oridonin attenuates low shear stress-induced endothelial cell dysfunction and oxidative stress by activating the nuclear factor erythroid 2-related factor 2 pathway

Zhipeng Chen, Heqian Liu, Xiaoqi Zhao, Subinur Mamateli, Cheng Liu, Lei Wang, Jing Yu, Yutong Liu, Jing Cai, Tong Qiao

A defined anthocyanin mixture sourced from bilberry and black currant inhibits Measles virus and various herpesviruses

Rinu Sivarajan, Heike Oberwinkler, Valeria Roll, Eva-Maria König, Maria Steinke, Jochen Bodem

Correction: Larrea divaricata: anti-inflammatory and antioxidant effects on macrophages and low density lipoproteins

  • Open Access
  • Correction

Ignacio Peralta, Carla Marrassini, Malen Saint Martin, Laura Cogoi, Maria Rosario Alonso, Alejandro Gugliucci, Claudia Anesini

Retraction Note: Chinese medicine Di-Huang-Yi-Zhi protects PC12 cells from H2O2-induced apoptosis by regulating ROS-ASK1-JNK/p38 MAPK signaling

  • Open Access
  • Retraction Note

Li-Min Zhang, Rong-Rong Zhen, Chao Gu, Tian-Li Zhang, Yue Li, Miao Jin, Bing Hu, Hong-Mei An

Hydroalcoholic extract of Haematoxylum brasiletto protects Caenorhabditis elegans from cadmium-induced toxicity

Margareth Duran-Izquierdo, María Taboada-Alquerque, Lucellys Sierra-Marquez, Neda Alvarez-Ortega, Elena Stashenko, Jesus Olivero-Verbel

Qin Huang formula enhances the effect of Adriamycin in B-cell lymphoma via increasing tumor infiltrating lymphocytes by targeting toll-like receptor signaling pathway

Weili Li, Lingling Lv, Ming Ruan, Jiayue Xu, Wenhua Zhu, Qiong Li, Xufeng Jiang, Lan Zheng, Weirong Zhu

Quantitative proteomic analysis of Bi Zhong Xiao decoction against collagen-induced arthritis rats in the early and late stages

Cailin He, Yang Wang, Yuqi Wen, Teng Li, En Hu, Siqing Zeng, Xingui Xiong

Aromatherapy with single essential oils can significantly improve the sleep quality of cancer patients: a meta-analysis

  • Open Access
  • Research

Hui Cheng, Lu Lin, Shaotong Wang, Yueyue Zhang, Tingting Liu, Yang Yuan, Qiuyun Chen, Li Tian

Ginsenoside Rg3 induces apoptosis and inhibits proliferation by down-regulating TIGAR in rats with gastric precancerous lesions

Shangbin Lv, Xiaodong Chen, Yu Chen, Daoyin Gong, Gang Mao, Caifei Shen, Ting Xia, Jing Cheng, Zhaoliang Luo, Yu Cheng, Weihong Li, Jinhao Zeng

Resveratrol pre-treatment alleviated caerulein-induced acute pancreatitis in high-fat diet-feeding mice via suppressing the NF-κB proinflammatory signaling and improving the gut microbiota

Xiaoying Zhang, Guodong Yang, Yulin Chen, Zhao Mu, Haiyue Zhou, Luoyao Zhang

Identification of core genes associated with the anti-atherosclerotic effects of Salvianolic acid B and immune cell infiltration characteristics using bioinformatics analysis

Zheng Jin, Huanyi Zhao, Yuan Luo, Xiushen Li, Jiayan Cui, Jing Yan, Pingzhen Yang

A narrative review on yoga: a potential intervention for augmenting immunomodulation and mental health in COVID-19

Indranill Basu-Ray, Kashinath Metri, Dibbendhu Khanra, Rishab Revankar, Kavitha M. Chinnaiyan, Nagaratna Raghuram, Mahesh Chandra Mishra, Bhushan Patwardhan, Manjunath Sharma, Ishwar V. Basavaraddi, Akshay Anand, Shrinath Reddy, K. K. Deepak, Marian Levy, Sue Theus, Glenn N. Levine, Holger Cramer, Gregory L. Fricchione, Nagendra R. Hongasandra

Evaluation of Annona muricata extract against Staphylococcus aureus isolate and in-silico activity of bioactive compounds against Capsular protein (Cap5O)

Uwem Okon Edet, Francisca Obiageri Nwaokorie, Elizabeth Nkagafel Mbim, Edet Effiong Asanga, Yeneochia Ogar Agbor, Henshaw Uchechi Okoroiwu, Bassey Okon Edet, Nikita Umoafia, Ani Nkang

Metformin and Gegen Qinlian Decoction boost islet α-cell proliferation of the STZ induced diabetic rats

Li Xu, Shreyas Jois, Hongliang Cui

Antibacterial and antibiotic-potentiation activity of the constituents from aerial part of Donella welwitshii (Sapotaceae) against multidrug resistant phenotypes

Michel-Gael F. Guefack, Marcelle O. Ngangoue, Armelle T. Mbaveng, Paul Nayim, Jenifer R. N. Kuete, Carine M. N. Ngaffo, Godloves F. Chi, Bathelemy Ngameni, Bonaventure T. Ngadjui, Victor Kuete

Retraction Note: In vitro and in vivo anti-colon cancer effects of Garcinia mangostana xanthones extract

Abdalrahim F. A. Aisha, Khalid M. Abu-Salah, Zhari Ismail, Amin Malik Shah Abdul Majid

Curative effects of fucoidan on acetic acid induced ulcerative colitis in rats via modulating aryl hydrocarbon receptor and phosphodiesterase-4

Alaa Bagalagel, Reem Diri, Ahmad Noor, Deina Almasri, Hussain T. Bakhsh, Hussam I. Kutbi, Mohammed M. H. Al-Gayyar

Human liver microsomes study on the inhibitory effect of plantainoside D on the activity of cytochrome P450 activity

  • Open Access
  • Research

Jin Zhou, Xian Qian, Yanqing Zhou, Shili Xiong, Shuxia Ji, Ying Wang, Ping Zhao

Berberine ameliorates mesenteric vascular dysfunction by modulating perivascular adipose tissue in diet-induced obese in rats

Man Wang, Xufang Geng, Kaipeng Li, Yawen Wang, Xiaofeng Duan, Congcong Hou, Lili Zhao, Huimin Zhou, Ding Zhao

Network pharmacology-based analysis and experimental in vitro validation on the mechanism of Paeonia lactiflora Pall. in the treatment for type I allergy

  • Open Access
  • Research

Yang Zhao, Hui Li, Xiangsheng Li, Yizhao Sun, Yuxin Shao, Yanfen Zhang, Zhongcheng Liu

A comprehensive search string informed by an operational definition of complementary, alternative, and integrative medicine for systematic bibliographic database search strategies

  • Open Access
  • Research

Jeremy Y. Ng, Tushar Dhawan, Ekaterina Dogadova, Zhala Taghi-Zada, Alexandra Vacca, Renee-Gabrielle Fajardo, Hooriya A. Masood, Riva Patel, Samira Sunderji, L. Susan Wieland, David Moher

The effect of hydroalcoholic extract of Psidium guajava L. on experimentally induced oral mucosal wound in rat

Faezeh Ghaderi, Elham Ebrahimi, Fatemeh Sari Aslani, Omid Koohi-Hosseinabadi, Farhad Koohpeyma, Cambyz Irajie, Nader Tanideh, Aida Iraji

Use of Complementary and Alternative Medicine in the context of cancer; prevalence, reasons for use, disclosure, information received, risks and benefits reported by people with cancer in Norway 

  • Open Access
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Agnete E. Kristoffersen, Jorunn V. Nilsen, Trine Stub, Johanna Hök Nordberg, Barbara Wider, Dana Mora, Kiwumulo Nakandi, Mona Bjelland

Antibacterial and anti-trichomunas characteristics of local landraces of Lawsonia inermis L.

M. Fatahi Bafghi, S. Salary, F. Mirzaei, H. Mahmoodian, H. Meftahizade, R. Zareshahi

A triangulated perspective for understanding CAM use in Lebanon: a qualitative study

  • Open Access
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Zeinab Jaafar, Jennifer Ayoub, Rena Hamadeh, Samar Baydoun, Gladys Honein-AbouHaidar, Jinan Banna, Mohamad Alameddine, Farah Naja

Prevalence of complementary and alternative medicine use in Brazil: results of the National Health Survey, 2019

Patricia de Moraes Mello Boccolini, Karine de Lima Sírio Boclin, Islândia Maria Carvalho de Sousa, Cristiano Siqueira Boccolini

A double-blind, randomised cross-over study to evaluate the absorption of a commercially available Ginkgo biloba extract compared to the liposomal extract Ginkgosome

  • Open Access
  • Research

David Briskey, Amanda Rao

Virtual screening of Indonesian herbal compounds as COVID-19 supportive therapy: machine learning and pharmacophore modeling approaches

Linda Erlina, Rafika Indah Paramita, Wisnu Ananta Kusuma, Fadilah Fadilah, Aryo Tedjo, Irandi Putra Pratomo, Nabila Sekar Ramadhanti, Ahmad Kamal Nasution, Fadhlal Khaliq Surado, Aries Fitriawan, Khaerunissa Anbar Istiadi, Arry Yanuar

Genistein attenuated oxidative stress, inflammation, and apoptosis in L-arginine induced acute pancreatitis in mice

Prasong Siriviriyakul, Jumlongluk Sriko, Kanjana Somanawat, Maneerat Chayanupatkul, Naruemon Klaikeaw, Duangporn Werawatganon

Rhein promotes the proliferation of keratinocytes by targeting oestrogen receptors for skin ulcer treatment

Ning Xu, Yuanran Chen, Dongjie Guo, Yu Deng, Wanjun Guo, Xin Liu, Yi Wang, Hanzhi Lu, Aijun Liu, Jianyong Zhu, Fulun Li

Network pharmacology and molecular docking technology-based predictive study of the active ingredients and potential targets of rhubarb for the treatment of diabetic nephropathy

Shaojie Fu, Yena Zhou, Cong Hu, Zhonggao Xu, Jie Hou

Pulsatilla decoction suppresses matrix metalloproteinase-7-mediated leukocyte recruitment in dextran sulfate sodium-induced colitis mouse model

Ming-Kuem Lin, Ya-Ting Yang, Li-Jen Lin, Wei-Hsuan Yu, Huan-Yuan Chen

Classifying knowledge used in complementary medicine consultations: a qualitative systematic review

  • Open Access
  • Research

Kate Davies, Milena Heinsch, Campbell Tickner, Caragh Brosnan, Amie Steel, Gupteswar Patel, Molly Marsh

Salvia-Nelumbinis naturalis improves lipid metabolism of NAFLD by regulating the SIRT1/AMPK signaling pathway

Yang Liu, Yiping Li, Jue Wang, Lili Yang, Xiao Yu, Ping Huang, Haiyan Song, Peiyong Zheng

Harpagoside attenuates local bone Erosion and systemic osteoporosis in collagen-induced arthritis in mice

Ju-Young Kim, Yoon-Hee Cheon, Sung-Jun Ahn, Sung Chul Kwak, Chong Hyuk Chung, Chang Hoon Lee, Myeung Su Lee

The effects of the ethanol extract of Cordia myxa leaves on the cognitive function in mice

Gülsen Kendir, Ho Jung Bae, Jihyun Kim, Yongwoo Jeong, Hyo Jeoung Bae, Keontae Park, Xingquan Yang, Young-jin Cho, Ji-Young Kim, Seo Yun Jung, Ayşegül Köroğlu, Dae Sik Jang, Jong Hoon Ryu

Traditional Chinese medicine formula 01 for nasopharyngeal carcinoma (NPC01) for head & neck cancer and health-related quality of life: a retrospective study

  • Open Access
  • Research article

Li Yanwei, He Feng, Wang Xudong, Pan Zhanyu

Exploring in vitro anti-proliferative and anti-inflammatory activities of Prasachandaeng remedy, and its bioactive compounds

Nuntika Prommee, Arunporn Itharat, Pakakrong Thongdeeying, Sunita Makchuchit, Weerachai Pipatrattanaseree, Adis Tasanarong, Buncha Ooraikul, Neal M. Davies

Herbal Medicine (HM) among pharmacy professionals working in drug retail outlets in Asmara, Eritrea: knowledge, attitude and prevalence of use

  • Open Access
  • Research

Alemseghed Goitom, Feruz Yemane, Mussie Tsegay, Amanuel Kifleyesus, Senai Mihreteab Siele, Eyasu H. Tesfamariam, Nuru Abdu

Antimicrobial Evaluation of Sequentially extracted Leaf of Vernonia auriculifera Hiern (Rejicho)

  • Open Access
  • Research

Teshale Etiso Wado, Sultan Suleman, Tesfaye Mohammed

Toxicity and toxicokinetics of the ethanol extract of Zuojin formula

Shuo Wang, Tao Zhang, Xiaoyan Liu, Zheng Yang, Ludi Li, Danping Shan, Yadong Gao, Yingzi Li, Yanying Li, Youbo Zhang, Qi Wang

Antimalarial activity of solvent fractions of a leaf of Eucalyptus globulus labill against Plasmodium berghei infected mice

Mihret Ayalew, Seyfe Asrade Atnafie, Azmeraw Bekele

NK cell-mediated immunostimulatory effects of ethanol extract of Morinda citrifolia (noni) fruit

  • Open Access
  • Research

Haeyeop Kim, Laily Rahmawati, Yo Han Hong, Su-Young Choi, Jae Youl Cho

Phytochemical profile and antimicrobial activity of the leaves and stem bark of Symphonia globulifera L.f. and Allophylus abyssinicus (Hochst.) Radlk

Ben Lukubye, Clement Olusoji Ajayi, Rapheal Wangalwa, Grace Kagoro-Rugunda

The effect of a chrysanthemum water extract in protecting the retina of mice from light damage

  • Open Access
  • Research

Yibo Gong, Xuechun Wang, Yuchuan Wang, Peng Hao, Hao Wang, Yatu Guo, Wei Zhang

Proportion and associated factors of the utilisation of complementary and alternative medicine exclusively in a hospital in Bangladesh

  • Open Access
  • Research

Md. Shahjalal, Jeff Gow, Md. Ashfikur Rahman, Md. Jakir Hossain, Md. Nafiul Alam Khan, Md. Sazzadul Alam, Ahmed Hossain, Rashidul Alam Mahumud

Effect of Rosemary Cream on Episiotomy Wound Healing in Primiparous Women: A Randomized Clinical Trial

Fatemeh Hadizadeh-Talasaz, Fariba Mardani, Narjes Bahri, Hassan Rakhshandeh, Nasim Khajavian, Marzieh Taghieh

Antibacterial interactions between two monofloral honeys and several topical antiseptics, including essential oils

Brayden H. Gray, Kathryn J. Green, Robbie R. Haines, Katherine A. Hammer

In-vitro determination of antimicrobial activities of Eruca sativa seed oil against antibiotic-resistant gram-negative clinical isolates from neonates: a future prospect

Rasha H. Bassyouni, Zeinat Kamel, Alkassem Ahmed Algameel, Ghada Ismail, Sylvana N. Gaber

Correction: GlucoMedix®, an extract of Stevia rebaudiana and Uncaria tomentosa, reduces hyperglycemia, hyperlipidemia, and hypertension in rat models without toxicity: a treatment for metabolic syndrome

León F. Villegas Vílchez, Julio Hidalgo Ascencios, Thomas P. Dooley

Comparison of intranasal and intraperitoneal administration of Eugenia caryophyllata (clove) essential oil on spatial memory, anxiety-like behavior and locomotor activity in a pilocarpine-induced status epilepticus rat model

Fatemeh Parvizi, Soraya Mehrabi, Ayeh Naghizadeh, Mohammad Kamalinejad‬, Sepide Goudarzi, ‬‬‬‬‬‬‬‬‬‬ Maryam Farahmandfar

Effects of plant-based medicinal food on postoperative recurrence and lung metastasis of gastric cancer regulated by Wnt/β-catenin-EMT signaling pathway and VEGF-C/D-VEGFR-3 cascade in a mouse model

Lin Tian, Xuxi Chen, Li Cao, Lishi Zhang, Jinyao Chen

Safety and use of complementary and alternative medicine in Norway during the first wave of the COVID-19 pandemic using an adapted version of the I-CAM-Q; a cross-sectional survey

Agnete Egilsdatter Kristoffersen, Miek C. Jong, Johanna Hök Nordberg, Esther T. van der Werf, Trine Stub

Antidiabetic potential of Lysiphyllum strychnifolium (Craib) A. Schmitz compounds in human intestinal epithelial Caco-2 cells and molecular docking-based approaches

Kunwadee Noonong, Kanta Pranweerapaiboon, Kulathida Chaithirayanon, Kantamat Surayarn, Phicharinee Ditracha, Narin Changklungmoa, Pornanan Kueakhai, Poonsit Hiransai, Kingkan Bunluepuech

Retraction Note: Xia-yu-xue decoction (XYXD) reduces carbon tetrachloride (CCl4)-induced liver fibrosis through inhibition hepatic stellate cell activation by targeting NF-κB and TGF-β1 signaling pathways

  • Open Access
  • Retraction Note

Cheng Liu, Xia Yuan, Le Tao, Zhuoan Cheng, Xiuqin Dai, Xia Sheng, Dongying Xue

Healthcare practitioner perceptions on barriers impacting cannabis prescribing practices

Yasmina Hachem, Sara J. Abdallah, Sergio Rueda, Jessica L. Wiese, Kamna Mehra, Jennifer Rup, Juthaporn Cowan, Antonio Vigano, Cecilia T. Costiniuk

Study of effect of guided meditation on quality of life in patients of end stage renal disease (ESRD) on maintenance hemodialysis – a randomised controlled trial

Bhalendu S. Vaishnav, Jekishan Jayeshbhai Hirapara, Maulin K. Shah

Methanolic neem (Azadirachta indica) stem bark extract induces cell cycle arrest, apoptosis and inhibits the migration of cervical cancer cells in vitro

Saurav Kumar, Vaishali Mulchandani, Jayasri Das Sarma

Practicing traditional Chinese medicine in the COVID-19 pandemic in Switzerland – an exploratory study

Angélique Bourqui, Pierre-Yves Rodondi, Emna El May, Julie Dubois

The ameliorative role of specific probiotic combinations on bone loss in the ovariectomized rat model

Ahmad Gholami, Mohammad Hossein Dabbaghmanesh, Younes Ghasemi, Farhad Koohpeyma, Pedram Talezadeh, Nima Montazeri-Najafabady

Edible algae (Ecklonia cava) bioprocessed with mycelia of shiitake (Lentinula edodes) mushrooms in liquid culture and its isolated fractions protect mice against allergic asthma

Kyung Hee Lee, Yeo Jin Jang, Woon Sang Hwang, Ki Sun Kwon, Wha Young Lee, Jeanman Kim, Sung Phil Kim, Mendel Friedman

Music-induced analgesia for adults and older adults during femoral arterial sheath removal after cardiac catheterization: a randomized clinical trial protocol

  • Open Access
  • Care
  • Study protocol

Kauanny Vitoria Gurgel dos Santos, Karena Cristina da Silva Leal, Louise Constancia de Melo Alves Silva, Kleyton Santos de Medeiros, Alexsandra Rodrigues Feijão, Maria do Carmo de Oliveira, Daniele Vieira Dantas, Rodrigo Assis Neves Dantas

Ethnobotanical study of Hakka traditional medicine in Ganzhou, China and their antibacterial, antifungal, and cytotoxic assessments

  • Open Access
  • Research article

Haibo Hu, Yanfang Yang, Abdallah Aissa, Volkan Tekin, Jialin Li, Sujogya Kumar Panda, Hao Huang, Walter Luyten

Alpinia officinarum Rhizome ameliorates the UVB induced photoaging through attenuating the phosphorylation of AKT and ERK

Jong Min Jung, Oh Yun Kwon, Jong Kyu Choi, Seung Ho Lee

Salvianolic acid A alleviates lipopolysaccharide-induced disseminated intravascular coagulation by inhibiting complement activation

Qi-Yun Zhang, Jing Guo, Lin Xu, Ying Wei, Shu-Ting Zhou, Qing-Yu Lu, Li Guo, Qian-Yun Sun

Retraction Note: Melastoma malabathricum Linn attenuates complete freund’s adjuvant-induced chronic inflammation in Wistar rats via inflammation response

  • Open Access
  • Retraction Note

Vikas Kumar, Prakash Chandra Bhatt, Kalicharan Sharma, Mahfoozur Rahman, Dinesh Kumar Patel, Nikunj Sethi, Atul Kumar, Nikhil Kumar Sachan, Gaurav Kaithwas, F. A. Al-abbasi, Firoz Anwar, Amita Verma

Understanding of black salve toxicity by multi-compound cytotoxicity assays

Andrew Croaker, Arie Davis, Anthony Carroll, Lei Liu, Stephen P. Myers

Lifestyle and health behaviour change support in traditional acupuncture: a mixed method survey study of reported practice (UK)

J. Pinto, K. Bradbury, D. Newell, F. L. Bishop

Selected coffee (Coffea arabica L.) extracts inhibit intestinal α-glucosidases activities in-vitro and postprandial hyperglycemia in SD Rats

Haimanot Mitiku, Tae Yang Kim, Hanna Kang, Emmanouil Apostolidis, Jung-Yun Lee, Young-In Kwon

Novel mechanism of napabucasin, a naturally derived furanonaphthoquinone: apoptosis and autophagy induction in lung cancer cells through direct targeting on Akt/mTOR proteins

  • Open Access
  • NSCLC
  • Research

Korrakod Petsri, Sunisa Thongsom, Satapat Racha, Supakarn Chamni, Saresa Jindapol, Nantawat Kaekratoke, Hongbin Zou, Pithi Chanvorachote

Prevalence and associated factors of complementary and integrative medicine use in patients afflicted with COVID-19

Mohammad Mahdi Parvizi, Sedigheh Forouhari, Reza Shahriarirad, Sepehr Shahriarirad, Ryan D Bradley, Leila Roosta

Prevalence, determinants and outcomes of traditional, complementary and alternative medicine use for hypertension among low-income households in Malaysia and the Philippines

Lia M. Palileo-Villanueva, Benjamin Palafox, Arianna Maever L. Amit, Veincent Christian F. Pepito, Fadhlina Ab-Majid, Farnaza Ariffin, Dina Balabanova, Mohamad-Rodi Isa, Nafiza Mat-Nasir, Mazapuspavina My, Alicia Renedo, Maureen L. Seguin, Khalid Yusoff, Antonio L. Dans, Martin Mckee

Pharmacological mechanism and therapeutic efficacy of Icariside II in the treatment of acute ischemic stroke: a systematic review and network pharmacological analysis

Xu Wang, Jinjian Li, Lifang Liu, Jun-Ming Kan, Ping Niu, Zi-Qiao Yu, Chunyu Ma, Fuxiang Dong, Mo-Xuan Han, Jinhua Li, De-xi Zhao

Effect and mechanisms of kaempferol against endometriosis based on network pharmacology and in vitro experiments

Junde Zhao, Juntao Wang, Jinxing Liu, Shuling Li, Pengfei Liu, Xiaodan Zhang

Topical administration of Juglans regia L. leaf extract accelerates diabetic wound healing

Davood Nasiry, Ali Reza Khalatbary, Alireza Ghaemi, Mohammad Ali Ebrahimzadeh, Mohammad Hossein Hosseinzadeh

Comparative evaluation of propolis nanostructured lipid carriers and its crude extract for antioxidants, antimicrobial activity, and skin regeneration potential

  • Open Access
  • Research

Ola M. Elkhateeb, Mohamed E. I. Badawy, Ahmed E. Noreldin, Howaida M. Abou-Ahmed, Mahmoud H. El-Kammar, Hoda A. Elkhenany

Exploring the protective mechanism of baicalin in treatment of atherosclerosis using endothelial cells deregulation model and network pharmacology

Mingshuang Li, Conglin Ren

Bioprospecting of endophytic actinobacterium associated with Aloe ferox mill for antibacterial activity

Tsolanku Sidney Maliehe, Melusi Mbambo, Londeka Sibusisiwe Ngidi, Jabulani Siyabonga Emmanuel Shandu, Ofentse Jacob Pooe, Peter Masoko, Tlou Nelson Selepe

Anti-inflammatory, cytotoxicity and antilipidemic properties: novel bioactivities of true cinnamon (Cinnamomum zeylanicum Blume) leaf

  • Open Access
  • Research

Walimuni Prabhashini Kaushalya Mendis Abeysekera, Galbada Arachchige Sirimal Premakumara, Wanigasekera Daya Ratnasooriya, Walimuni Kanchana Subhashini Mendis Abeysekera

Correction: Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

  • Open Access
  • Correction

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa‑Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani, Gaber El‑Saber Batiha

Antioxidative, anticancer, and antibacterial activities of a nanogel containing Mentha spicata L. essential oil and electrospun nanofibers of polycaprolactone-hydroxypropyl methylcellulose

Fatemeh Rasti, Yaser Yousefpoor, Abbas Abdollahi, Mojdeh Safari, Ghazaal Roozitalab, Mahmoud Osanloo

Evaluation of therapeutic effects of crocin in attenuating the progression of diabetic nephropathy: a preliminary randomized triple-blind placebo-controlled trial

Asma Jaafarinia, Behzad Kafami, Adeleh Sahebnasagh, Fatemeh Saghafi

Complementary medicine usage in surgery: a cross-sectional survey in Germany

  • Open Access
  • Research

Ann-Kathrin Lederer, Yvonne Samstag, Thomas Simmet, Tatiana Syrovets, Roman Huber

Extracts from Argentinian native plants reverse fluconazole resistance in Candida species by inhibiting the efflux transporters Mdr1 and Cdr1

Florimar Gil, Jerónimo Laiolo, Brayan Bayona-Pacheco, Richard D. Cannon, Antonio Ferreira-Pereira, María Cecilia Carpinella

Ayurvedic formulations Guduchi and Madhuyashti triggers JNK signaling mediated immune response and adversely affects Huntington phenotype

  • Open Access
  • Research article

Surabhi Singh, Madhu G. Tapadia

Antimalarial potential of compounds isolated from Mammea siamensis T. Anders. flowers: in vitro and molecular docking studies

Prapaporn Chaniad, Arnon Chukaew, Apirak Payaka, Arisara Phuwajaroanpong, Tachpon Techarang, Walaiporn Plirat, Chuchard Punsawad

Retraction Note: Neuroprotective effect of Buyang Huanwu Decoction on spinal ischemia-reperfusion injury in rats is linked with inhibition of cyclin-dependent kinase 5

  • Open Access
  • Retraction Note

Lei Wang, Dian-Ming Jiang

Reproductive and endocrine effects of artemisinin, piperaquine, and artemisinin-piperaquine combination in rats

  • Open Access
  • Research

Xiaobo Li, Yueming Yuan, Yingyi Chen, Li Ru, Zheng Yuan, Zhiyong Xu, Qin Xu, Jianping Song, Guoming Li, Changsheng Deng

The protective effect of L-carnitine on testosterone synthesis pathway, and spermatogenesis in monosodium glutamate-induced rats

Farhad Koohpeyma, Fatemeh Gholizadeh, Hannaneh Hafezi, Mehri Hajiaghayi, Morvarid Siri, Shaghayegh Allahyari, Mohammad Hasan Maleki, Naeimehossadat Asmarian, Elahe Bayat, Sanaz Dastghaib

Cistanche tubulosa phenylethanoid glycosides suppressed adipogenesis in 3T3-L1 adipocytes and improved obesity and insulin resistance in high-fat diet induced obese mice

Dilinazi Abudujilile, Weilan Wang, Alimu Aimaier, Lili Chang, Yuliang Dong, Yiye Wang, Xu Fan, Yu Ma, Yongli Wang, Dilinigeer Ziyayiding, Yuan Ma, Jie Lv, Jinyao Li

Fallopia Japonica and Prunella vulgaris inhibit myopia progression by suppressing AKT and NFκB mediated inflammatory reactions

Chih-Sheng Chen, Yu-An Hsu, Chia-Hung Lin, Yao-Chien Wang, En-Shyh Lin, Ching-Yao Chang, Jamie Jiin-Yi Chen, Ming-Yen Wu, Hui-Ju Lin, Lei Wan

Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani, Gaber El-Saber Batiha

Pingyin rose essential oil alleviates LPS-Induced inflammation in RAW 264.7 cells via the NF-κB pathway: an integrated in vitro and network pharmacology analysis

  • Open Access
  • Research

Rifat Nowshin Raka, Ding Zhiqian, Yuan Yue, Qiao Luchang, Park Suyeon, Xiao Junsong, Wu Hua

Network toxicology and molecular docking analyses on strychnine indicate CHRM1 is a potential neurotoxic target

Jialin Dai, Jiangjin Liu, Maoxin Zhang, Yanni Yu, Jie Wang

Observation on clinical effect of Huoxue-Jiangtang decoction formula granules in treating prediabetes: a randomized prospective placebo-controlled double-blind trial protocol

Peng-Xiang Zhang, Lin Zeng, Lu Meng, Hui-Lin Li, Heng-Xia Zhao, De-Liang Liu

Network pharmacology and molecular docking-based prediction of active compounds and mechanisms of action of Cnidii Fructus in treating atopic dermatitis

Shakeel Ahmad Khan, Ying Wu, Amy Sze-Man Li, Xiu-Qiong Fu, Zhi-Ling Yu

Efficacy and safety of curcuminoids alone in alleviating pain and dysfunction for knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials

Jie Feng, Zhao Li, Linling Tian, Panyun Mu, Yimei Hu, Feng Xiong, Xu Ma

Retraction Note: Angelica sinensis polysaccharide prevents mitochondrial apoptosis by regulating the Treg/Th17 ratio in aplastic anemia

Zetao Chen, Li Cheng, Jing Zhang, Xing Cui

Simiao pill inhibits epithelial mesenchymal transition in a mouse model of chronic hyperuricemic nephropathy by inhibiting NLRP3 inflammasome activation

Guangxing Shui, Zheyi Cai, Feng Wang, Ting Chen, Xueyuan Huang, Yun Cai, Xiuhua Mi

Sub-chronic oral toxicity screening of quercetin in mice

  • Open Access
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Patrice Cunningham, Emma Patton, Brandon N. VanderVeen, Christian Unger, Ahmed Aladhami, Reilly T. Enos, Sarah Madero, Ioulia Chatzistamou, Daping Fan, E. Angela Murphy, Kandy T. Velázquez

Screening and evaluation of cytotoxicity and antiviral effects of secondary metabolites from water extracts of Bersama abyssinica against SARS-CoV-2 Delta

Never Zekeya, Bertha Mamiro, Humphrey Ndossi, Rehema Chande Mallya, Mhuji Kilonzo, Alex Kisingo, Mkumbukwa Mtambo, Jafari Kideghesho, Jaffu Chilongola

Mechanisms of action of Zishen Yutai pills in treating premature ovarian failure determined by integrating UHPLC-Q-TOF-MS and network pharmacology analysis

  • Open Access
  • Research

Lei Dang, Chunbo Zhang, Biru Su, Na Ning, Qiuling Huang, Su Zhou, Meng Wu, Wenqing Ma, Man Wang, Pengfei Cui, Yan Li, Shixuan Wang

The effect of complementary music intervention on the patients’ quality of life after septoplasty and rhinoplasty

Angela Schell, Felix Wassmer, Lena Zaubitzer, Benedikt Kramer, Haneen Sadick, Nicole Rotter, Daniel Häussler

“I wouldn’t have joined if it wasn’t online”: understanding older people’s engagement with teleyoga classes for fall prevention

  • Open Access
  • Research

Abby Haynes, Heidi Gilchrist, Juliana S Oliveira, Catherine Sherrington, Anne Tiedemann

Long-term evaluation of safety and biological effects of Korean Red Ginseng (Panax Ginseng): a long-term in vivo study

  • Open Access
  • Research

Soo Kyung Park, Sung-Won Kim, Hwi Won Seo, Sun Hee Hyun, Jong-Su Kyung, Soo-Hyun Youn, Seung Ho So, Gyo In, Chae-Kyu Park, Eugene C. Yi, Chang-Kyun Han, Yong Yook Lee

Optimisation of Calophyllum inophyllum seed oil nanoemulsion as a potential wound healing agent

  • Open Access
  • Research article

Elnaz Saki, Vinuthaa Murthy, Roshanak Khandanlou, Hao Wang, Johanna Wapling, Richard Weir

Editorial expression of concern: Retama monosperma n-hexane extract induces cell cycle arrest and extrinsic pathway-dependent apoptosis in jurkat cells

  • Open Access
  • Editorial Expression of Concern

Lamiae Belayachi, Clara Aceves-Luquero, Nawel Merghoub, Youssef Bakri, Silvia Fernández de Mattos, Saaïd Amzazi, Priam Villalonga

Effects of qigong exercise on the physical and mental health of college students: a systematic review and Meta-analysis

Jianping Lin, Yi fang Gao, Yue Guo, Ming Li, Yuxiang Zhu, Ruoshi You, Shaoqing Chen, Shizhong Wang

RETRACTED ARTICLE: Polyphenols from Conyza dioscoridis (L.) ameliorate Alzheimer’s disease- like alterations through multi-targeting activities in two animal models

Adel A. Gomaa, Hanan S. M. Farghaly, Rania M. Makboul, Abeer M. Hussien, Mariam A. Nicola

Formulation of Cinnamon (Cinnamomum verum) oil loaded solid lipid nanoparticles and evaluation of its antibacterial activity against Multi-drug Resistant Escherichia coli

Mehran Nemattalab, Masoumeh Rohani, Mehdi Evazalipour, Zahra Hesari

Classical music restored fertility status in rat model of premature ovarian failure

Nahideh Nazdikbin Yamchi, Mohammad Mojtaba Alizadeh Ashrafi, Hamed Abbasi, Farhad Amjadi, Mohammad Hossein Geranmayeh, Reza Shirazi, Amin Tamadon, Reza Rahbarghazi, Mahdi Mahdipour

Renoprotective effects of the ginger (Zingiber officinale) on Diabetic kidney disease, current knowledge and future direction: a systematic review of animal studies

Parisa Veisi, Meysam Zarezade, Helya Rostamkhani, Zohreh Ghoreishi

Awareness and use of home remedies in Italy’s alps: a population-based cross-sectional telephone survey

Wolfgang Wiedermann, Dietmar Ausserhofer, Anna Vögele, Ulrich Becker, Giuliano Piccoliori, Christian J. Wiedermann, Adolf Engl

Comparing the effect of body wash with marshmallow plant and lukewarm water on reducing the temperature of febrile children: a randomized clinical trial

Hadis Goodarzi, Fatemeh Valizadeh, Fatemeh Ghasemi, Farzad Ebrahimzade, Seyedeh Hanieh Seifosadat, Bahram Delfan, Nadereh Taee

Retraction Note: Improved glycemic control, pancreas protective and hepatoprotective effect by traditional poly-herbal formulation “Qurs Tabasheer” in streptozotocin induced diabetic rats

  • Open Access
  • Retraction Note

Danish Ahmed, Manju Sharma, Alok Mukerjee, Pramod W. Ramteke, Vikas Kumar

Baduanjin exercise for balance function in community-dwelling older adults with cognitive frailty: a randomized controlled trial protocol

  • Open Access
  • Study protocol

Yu Zhang, Jiawei Wu, Xiaoqian Wang, Guohua Zheng

Effect of Liuzijue on pulmonary rehabilitation in patients with chronic obstructive pulmonary disease: study protocol for a multicenter, non-randomized, prospective study

Jiaming Hu, Rundi Gao, Yiting Wang, Yan Li, Yaqin Wang, Zhen Wang, Junchao Yang

Effectiveness of acupuncture in the treatment of cyclic mastalgia: a study protocol for a randomized controlled trial

Chuan Yu, Jun Wang, Bin Shen, Xiang Li, Rui Zhang, Yan Qin, Guofan Jian, Jing Guo

A study protocol for a randomized controlled trial to assess the efficacy of Baduanjin exercise on older adults with sarcopenia in China

Shengnan Yue, Jing Zhang, Jiaxin Li, Yanwei Hao, Shaofeng Wang, Tianyu Liu, Wen Zhong, Chongli Chen, Fei Wang, Bin Li

Exploring the pharmacological mechanism of Shengjing capsule on male infertility by a network pharmacology approach

Ming Wang, Qi Wang, Hui Jiang, Yongqiang Du, Xiansheng Zhang

Safety of acupuncture by Korean Medicine Doctors: a prospective, practice-based survey of 37,490 consultations

Jiyoon Won, Jun-Hwan Lee, Heejung Bang, Hyangsook Lee

Antioxidant and anti-inflammatory activities of Centratherum anthelminticum (L.) Kuntze seed oil in diabetic nephropathy via modulation of Nrf-2/HO-1 and NF-κB pathway

Nida Baig, Rabia Sultan, Shamim Akhtar Qureshi

Ascorbic acid 6-palmitate modulates microglia M1/M2 polarization in lipopolysaccharide-stimulated BV-2 cells via PERK/elF2α mediated endoplasmic reticulum stress

  • Open Access
  • Research

Qian Li, Yao Wu, Xue-shen Chen, Tao Zeng, Lin-ling Liu, Zi-qi Feng, Dan-yang Liu, Ling Zhu, Li-hong Wan

Cinnamomum verum J. Presl. Bark essential oil: in vitro investigation of anti-cholinesterase, anti-BACE1, and neuroprotective activity

Mina Saeedi, Aida Iraji, Yasaman Vahedi-Mazdabadi, Atiyeh Alizadeh, Najmeh Edraki, Omidreza Firuzi, Mahdieh Eftekhari, Tahmineh Akbarzadeh

Correction: Complementary medicine usage in surgery: a cross-sectional survey in Germany

  • Open Access
  • Correction

Ann-Kathrin Lederer, Yvonne Samstag, Thomas Simmet, Tatiana Syrovets, Roman Huber

Retraction Note: Sedum sarmentosum Bunge extract ameliorates lipopolysaccharide- and D-galactosamine-induced acute liver injury by attenuating the hedgehog signaling pathway via regulation of miR-124 expression

  • Open Access
  • Retraction Note

Li Hao, Ming-wei Liu, Song-tao Gu, Xue Huang, Hong Deng, Xu Wang

Retraction Note: Effects of Panax notoginseng saponins on severe acute pancreatitis through the regulation of mTOR/Akt and caspase-3 signaling pathway by upregulating miR-181b expression in rats

Ming-wei Liu, Rui Wei, Mei-xian Su, Hui Li, Tian-wen Fang, Wei Zhang

New Baitouweng decoction combined with fecal microbiota transplantation alleviates DSS-induced colitis in rats by regulating gut microbiota metabolic homeostasis and the STAT3/NF-κB signaling pathway

Xin Gu, Zhiwei Miao, Yantian Wang, Yue Yang, Tongtong Yang, Yi Xu

Water extract from artichoke ameliorates high-fat diet-induced non-alcoholic fatty liver disease in rats

Aihua Deng, Fengying Liu, Xuchong Tang, Yun Wang, Peng Xie, Qifu Yang, Bing Xiao

The theranostic potentialities of bioavailable nanocurcumin in oral cancer management

Marwa M. Essawy, Mostafa M. Mohamed, Hanaa S. Raslan, Salma T. Rafik, Ashraf K. Awaad, Omneya R. Ramadan

Preliminary verification of the anti-hypoxia mechanism of Gentiana straminea maxim based on UPLC-triple TOF MS/MS and network pharmacology

Xiu mei Kong, Dan Song, Jie Li, Yi Jiang, Xiao ying Zhang, Xiao Jun Wu, Ming juan Ge, Jiao jiao Xu, Xiao min Gao, Qin Zhao

Randomized double-blind placebo-controlled multicenter trial for the effects of a polyherbal remedy, Yokukansan (YiganSan), in smokers with depressive tendencies

Maki Komiyama, Yuka Ozaki, Hiromichi Wada, Hajime Yamakage, Noriko Satoh-Asahara, Akihiro Yasoda, Yoichi Sunagawa, Tatsuya Morimoto, Shinji Tamaki, Masahiro Suzuki, Takuo Shibayama, Toru Kato, Yasumasa Okada, Toshiyuki Kita, Yuko Takahashi, Koji Hasegawa

Computation and molecular pharmacology to trace the anti-rheumatoid activity of Angelicae Pubescentis Radix

Junhao Zhang, Rui Wang, Xiao Liang, Hao Tian Bai, Ya Lan Li, Shuhui Sun, Qianqian Zhang, Jing Yang

Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway – an in vitro and in clinic study

  • Open Access
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Geng-He Chang, Pei-Rung Yang, Yu-Ching Cheng, Ke-Hsin Hsu, Ching-Yuan Wu, Yao-Hsu Yang, Yu-Shih Lin, Cheng-Ming Hsu, Ming-Shao Tsai, Yao-Te Tsai, Pey-Jium Chang

Correction: Cinnamomum verum J. Presl. Bark essential oil: in vitro investigation of anti-cholinesterase, anti-BACE1, and neuroprotective activity

  • Open Access
  • Correction

Mina Saeedi, Aida Iraji, Yasaman Vahedi-Mazdabadi, Atiyeh Alizadeh, Najmeh Edraki, Omidreza Firuzi, Mahdieh Eftekhari, Tahmineh Akbarzadeh

Effectiveness of Hypnosis for the Prevention of Anxiety During Coronary Angiography (HYPCOR study): a prospective randomized study

Laure Abensur Vuillaume, Charles Gentilhomme, Sandrine Weber, Nadia Ouamara, Julien Bayard, Mathieu Valla, Khalife Khalife, Christophe Goetz, Nazmine Guler

Musical therapy attenuates neuroma pain by modifying leptin expression

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  • Research

Yingying Lv, Junzhen Wu, Yongming Xu, Shaofeng Pu, Chen Li, Dongping Du

Mitochondrial toxicants in Xian-Ling-Gu-Bao induce liver injury by regulating the PI3K/mTOR signaling pathway: an in vitro study

Shujuan Piao, Hongwei Lin, Xia Tao, Wansheng Chen

Effects of Kami Guibi-tang in patients with mild cognitive impairment: study protocol for a phase III, randomized, double-blind, and placebo-controlled trial

Hee-Yeon Shin, Tae-Bin Yim, Hye-Min Heo, Geon-Ho Jahng, Seungwon Kwon, Seung-Yeon Cho, Seong-Uk Park, Woo-Sang Jung, Sang-Kwan Moon, Chang-Nam Ko, Jung-Mi Park

Assessing knowledge of herbal medicine course for dental students

Zuhair S. Natto

Quercetin ameliorates acute lung injury in a rat model of hepatopulmonary syndrome

Noha Abdel-Aziz Nassef, Manal S. Abd-El Hamid, Samy A. Abusikkien, Asmaa Ibrahim Ahmed

The significance of thymoquinone administration on liver toxicity of diazinon and cholinesterase activity; a recommendation for prophylaxis among individuals at risk

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Gholam-Hassan Danaei, Arian Amali, Mohammad Karami, Mohammad-Bagher Khorrami, Bamdad Riahi-Zanjani, Mahmood Sadeghi

Prevalence of late and long-term effects of cancer (treatment) and use of complementary and alternative medicine in Norway

Agnete E. Kristoffersen, Barbara Wider, Jorunn V. Nilsen, Mona Bjelland, Dana C. Mora, Johanna Hök Nordberg, Ann Ragnhild Broderstad, Kiwumulo Nakandi, Trine Stub

Pharmacokinetics and pharmacodynamics of bioactive compounds in Penyanqing preparation in THP-1 inflammatory cells induced by Lipopolysaccharide

Linna Gong, Zhishuo Miao, Li Zhang, Birui Shi, Zuoqi Xiao, Panzi Qiu, Menghua Liu, Wei Zou

In vitro and in silico analysis of ‘Taikong blue’ lavender essential oil in LPS-induced HaCaT cells and RAW264.7 murine macrophages

Mengya Wei, Fei Liu, Rifat Nowshin Raka, Jie Xiang, Junsong Xiao, Tingting Han, Fengjiao Guo, Suzhen Yang, Hua Wu

Frequency, types, and factors associated with complementary and alternative medicine use among patients on maintenance haemodialysis

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  • Research

Alex Tatang Mambap, Gwendoline Enda Ukum, Denis G. Teuwafeu, Mahamat Maimouna, Gloria Enow Ashuntantang

Public knowledge, attitudes, and practices towards herbal medicines; a cross-sectional study in Western Saudi Arabia

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Syed Faisal Zaidi, Sheikh Abdul Saeed, Muhammad Anwar Khan, Aslam Khan, Yaqoub Hazazi, Mohammed Otayn, Mohammed Rabah, Muhammad Daniyal

Mitigative effect of caffeine against diclofenac-induced hepato-renal damage and chromosomal aberrations in male albino rats

Mai M. Anwar, Ibrahim M. Ibrahim Laila

Biological isolation and characterization of Catharanthus roseus (L.) G. Don methanolic leaves extracts and their assessment for antimicrobial, cytotoxic, and apoptotic activities

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Somashekara Rajashekara, Dondapati Reena, Mullahalli Venkataramareddy Mainavi, Locheruvapalli Srinivasa Sandhya, Utpal Baro

Retraction Note: Calycosin-7-O-β-D-glucoside promotes oxidative stress-induced cytoskeleton reorganization through integrin-linked kinase signaling pathway in vascular endothelial cells

Yue-Hua Jiang, Wei Sun, Wei Li, Hong-Zhen Hu, Le Zhou, Hui-Hui Jiang, Jing-Xin Xu

Antimalarial and immunomodulatory potential of chalcone derivatives in experimental model of malaria

Shweta Sinha, Bikash Medhi, B. D. Radotra, Daniela I. Batovska, Nadezhda Markova, Ashish Bhalla, Rakesh Sehgal

Protective effect of silymarin on tacrolimus-induced kidney and liver toxicity

Funda Terzi, Mustafa Kemal Ciftci

Use of complementary and alternative medicine in pregnancy and labour pain: a cross-sectional study from turkey

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Ruşen Öztürk, Ayşe Emi̇nov, Gül Ertem

Integrated proteomics and metabolomics analysis of lumbar in a rat model of osteoporosis treated with Gushukang capsules

Ruohui Lin, Bingying Xie, Lihua Xie, Jirong Ge, Shengqiang Li

Anti-atherogenic and cardio-protective properties of sweet melon (Cucumis melo. L. Inodorus) seed extract on high fat diet induced obesity in male wistar rats

  • Open Access
  • Obesity
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G. Adebayo-Gege, V. Alicha, T. O. Omayone, S. C. Nzekwe, C. A. Irozuoke, O. A. Ojo, A. F. Ajayi

Cuscuta epithymum Murr. crude extract pre-conditioning protects C6 cells from L-glutamate-induced neurotoxicity

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  • Research

Masoumeh Pourhadi, Zahra Niknam, Rasoul Ghasemi, Mina Soufi Zomorrod, Vahid Niazi, Mehrdad Faizi, Hakimeh Zali, Faraz Mojab

Correction: Repair of osteochondral defect using icariin-conditioned serum combined with chitosan in rabbit knees

  • Open Access
  • Correction

Juntao Zhang, Dong Ming, Qiang Ji, Aifeng Liu, Chao Zhang, Jianjie Jiao, Man Shang

Efficacy, safety and therapeutic mechanism of Shen-Qi Xiao-Tan formula in the treatment of peripheral atherosclerosis in patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial protocol

Yulin Leng, Xiaoxu Fu, Lisen Qian, Qiqi Li, Hong Gao, Hongyan Xie, Chunguang Xie

Homeopathy for seasonal allergic rhinitis: rationale, design and methods of the three-armed randomized controlled HOMEOSAR trial

J. Siewert, M. Teut, K. Gaertner, S. Binting, C. Eberhardt, M. Ortiz, W. Grabowska, T. Reinhold, S. Roll, B. Stoeckigt, S. N. Willich, H. Cramer, B. Brinkhaus

Anti-glycation, antiplatelet and antioxidant effects of different pomegranate parts

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  • Research

Zahra Amri, Ikram Ben Amor, Amira Zarrouk, Raja Chaaba, Jalel Gargouri, Mohamed Hammami, Sonia Hammami

Combination of Quercetin or/and siRNA-loaded DDAB-mPEG-PCL hybrid nanoparticles reverse resistance to Regorafenib in colon cancer cells

Shabnam Shahidi, Kobra Rostamizadeh, Mojtaba Fathi, Keivan Nedaei, Ali Ramazani

Kampo formula hochu-ekki-to (Bu-Zhong-Yi-Qi-Tang, TJ-41) ameliorates muscle atrophy by modulating atrogenes and AMPK in vivo and in vitro

  • Open Access
  • Research article

Mitsutaka Yakabe, Tatsuya Hosoi, Hiroko Sasakawa, Masahiro Akishita, Sumito Ogawa

Knowledge, attitude, perceived effectiveness and self-practice of complementary and alternative medicine: a cross-sectional comparison between medical and non-medical students of Bangladesh

  • Open Access
  • Research

Mohammad Azmain Iktidar, Sreshtha Chowdhury, Simanta Roy, Mowshomi Mannan Liza, Sharmin Akter, A. M. Khairul Islam, Sefat Alam Pranto, Sristi Chowdhury, Md Asikur Rahman, Chowdhury Shama Binte Shafiul, Dipa Dev, Syed Md Sayeem Tanvir, Mohammad Hayatun Nabi

The ethanolic extract of Curcuma longa grown in Korea exhibits anti-neuroinflammatory effects by activating of nuclear transcription factor erythroid-2-related factor 2/heme oxygenase-1 signaling pathway

Kwan-Woo Kim, Young-Seob Lee, Dahye Yoon, Geum-Soog Kim, Dae Young Lee

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