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BMC Complementary Medicine and Therapies

Issue 1/2019

Content (374 Articles)

The anti-obesity effects of Tongbi-san in a high-fat diet-induced obese mouse model

  • Open Access
  • Obesity
  • Research article

Yea-Jin Park, Gui-Sun Lee, Se-Yun Cheon, Yun-Yeop Cha, Hyo-Jin An

Effect of Saururus chinensis leaves extract on type II collagen-induced arthritis mouse model

Jong-Hyun Nho, Hyeun-Joo Lee, Ho-Kyung Jung, Ji-Hun Jang, Ki-Ho Lee, A-Hyeon Kim, Tae-Kyoung Sung, Hyun-Woo Cho

Probiotics and yogurt modulate oxidative stress and fibrosis in livers of Schistosoma mansoni-infected mice

Manal F. El-Khadragy, Ebtesam M. Al-Olayan, Mohammed I. Y. Elmallah, Afra M. Alharbi, Hany M. Yehia, Ahmed E. Abdel Moneim

Bio-guided profiling and HPLC-DAD finger printing of Atriplex lasiantha Boiss

Tanzeel Zohra, Muhammad Ovais, Ali Talha Khalil, Muhammad Qasim, Muhammad Ayaz, Zabta Khan Shinwari, Sajjad Ahmad, Mohammad Zahoor

Use of alternative medicine, ginger and licorice among Danish pregnant women – a prospective cohort study

  • Open Access
  • Research article

Tabia Volqvartz, Anna Louise Vestergaard, Sissel Kramer Aagaard, Mette Findal Andreasen, Iana Lesnikova, Niels Uldbjerg, Agnete Larsen, Pinar Bor

In vitro evaluation of the activity of an essential oil from Pistacia vera L. variety Bronte hull against Candida sp.

Manuela D’Arrigo, Carlo Bisignano, Pierangela Irrera, Antonella Smeriglio, Roberto Zagami, Domenico Trombetta, Orazio Romeo, Giuseppina Mandalari

Antioxidants and α-glucosidase inhibitors from Neptunia oleracea fractions using 1H NMR-based metabolomics approach and UHPLC-MS/MS analysis

  • Open Access
  • Research article

Soo Yee Lee, Ahmed Mediani, Intan Safinar Ismail, Maulidiani, Faridah Abas

The traditional Chinese formulae Ling-gui-zhu-gan decoction alleviated non-alcoholic fatty liver disease via inhibiting PPP1R3C mediated molecules

Yanqi Dang, Shijun Hao, Wenjun Zhou, Li Zhang, Guang Ji

Danggui Buxue Tang, an ancient Chinese herbal decoction, protects β-amyloid-induced cell death in cultured cortical neurons

Guowei Gong, Baohui Qi, Yan T. Liang, Tina T. X. Dong, Huai Y. Wang, Karl W. K. Tsim, Yuzhong Zheng

Effects of ChondroT on potassium Oxonate-induced Hyperuricemic mice: downregulation of xanthine oxidase and urate transporter 1

Dool-Ri Oh, Jong Ro Kim, Chul Yung Choi, Chan-hun Choi, Chang-su Na, Bok Yun Kang, Seon-Jong Kim, Young Ran Kim

The ethanolic extract of Aralia continentalis ameliorates cognitive deficits via modifications of BDNF expression and anti-inflammatory effects in a rat model of post-traumatic stress disorder

Bombi Lee, Riwon Hong, Pooreum Lim, Daeun Cho, Mijung Yeom, Sanghyun Lee, Ki Sung Kang, Sang Cheon Lee, Insop Shim, Hyejung Lee, Dae-Hyun Hahm

Correction to: Effects of transcutaneous electrical nerve stimulation in the Management of Post-Injection Sciatic Pain in a non-randomized controlled clinical trial in Nnewi, Nigeria

Uchenna Prosper Okonkwo, Sam Chidi Ibeneme, Ebere Yvonne Ihegihu, Afamefuna Victor Egwuonwu, Ikechukwu Charles Ezema, Adesina Fatai Maruf, Emmanuel Chiebuka Okoye, Olanrewaju Peter Ibikunle, Antoninus Obinna Ezeukwu

Cognitive improvement effects of electro-acupuncture for the treatment of MCI compared with Western medications: a systematic review and Meta-analysis

Hwan Kim, Hong Kyoung Kim, Si Yeon Kim, Young Il Kim, Ho Ryong Yoo, In Chul Jung

Coreopsis tinctoria Nutt ameliorates high glucose-induced renal fibrosis and inflammation via the TGF-β1/SMADS/AMPK/NF-κB pathways

Lan Yao, Jie Li, Linlin Li, Xinxia Li, Rui Zhang, Yujie Zhang, Xinmin Mao

Suppression of lung inflammation by the ethanol extract of Chung-Sang and the possible role of Nrf2

  • Open Access
  • Research article

Jin-Woo Han, Kyun Ha Kim, Min-Jung Kwun, Jun-Yong Choi, Sang-Jun Kim, Seung-Il Jeong, Beom-Joon Lee, Kwan-Il Kim, Ran Won, Ji Hoon Jung, Hee Jae Jung, Myungsoo Joo

Correction to: Complementary and alternative medicine for treatment of atopic eczema in children under 14 years old: a systematic review and meta-analysis of randomized controlled trials

Chun-li Lu, Xue-han Liu, Trine Stub, Agnete E. Kristoffersen, Shi-bing Liang, Xiao Wang, Xue Bai, Arne Johan Norheim, Frauke Musial, Terje Alræk, Vinjar Fonnebo, Jian-ping Liu

Self-management strategies amongst Australian women with endometriosis: a national online survey

  • Open Access
  • Care
  • Research article

Mike Armour, Justin Sinclair, K. Jane Chalmers, Caroline A. Smith

Development of aqueous-based multi-herbal combination using principal component analysis and its functional significance in HepG2 cells

  • Open Access
  • Research article

Pardeep Kaur, Robin, Rajendra G. Mehta, Balbir Singh, Saroj Arora

Validation of the anti-infective potential of a polyherbal ‘Panchvalkal’ preparation, and elucidation of the molecular basis underlining its efficacy against Pseudomonas aeruginosa

Chinmayi Joshi, Pooja Patel, Hanmanthrao Palep, Vijay Kothari

Improvement of diabetic wound healing by topical application of Vicenin-2 hydrocolloid film on Sprague Dawley rats

Woan Sean Tan, Palanisamy Arulselvan, Shiow-Fern Ng, Che Norma Mat Taib, Murni Nazira Sarian, Sharida Fakurazi

The impact of peppermint oil on the irritable bowel syndrome: a meta-analysis of the pooled clinical data

N. Alammar, L. Wang, B. Saberi, J. Nanavati, G. Holtmann, R. T. Shinohara, G. E. Mullin

The effectiveness of self-care and lifestyle interventions in primary dysmenorrhea: a systematic review and meta-analysis

  • Open Access
  • Care
  • Research article

Mike Armour, Caroline A. Smith, Kylie A. Steel, Freya Macmillan

Absence of herb-drug interactions of mistletoe with the tamoxifen metabolite (E/Z)-endoxifen and cytochrome P450 3A4/5 and 2D6 in vitro

U. Weissenstein, M. Kunz, M. Oufir, J. T. Wang, M. Hamburger, K. Urech, U. Regueiro, S. Baumgartner

Combined antibacterial effect of essential oils from three most commonly used Ethiopian traditional medicinal plants on multidrug resistant bacteria

Eshetu Gadisa, Gebru Weldearegay, Kassu Desta, Getahun Tsegaye, Sityehu Hailu, Kefiyelewu Jote, Abera Takele

Preventive effects of a novel herbal mixture on atopic dermatitis-like skin lesions in BALB/C mice

Abraham Fikru Mechesso, Seung-Jin Lee, Na-Hye Park, Jin-Yoon Kim, Zi-Eum Im, Joo-Won Suh, Seung-Chun Park

Correction to: Perceptions of traditional Chinese medicine for chronic disease care and prevention: a cross-sectional study of Chinese hospital-based health care professionals

  • Open Access
  • Correction

Xiaoqing Fan, Fanli Meng, Dahui Wang, Qing Guo, Zhuoyu Ji, Lei Yang, Atsushi Ogihara

A randomized, double blind, placebo controlled, multicenter clinical trial to assess the efficacy and safety of Emblica officinalis extract in patients with dyslipidemia

Haridas Upadya, S. Prabhu, Aravinda Prasad, Deepa Subramanian, Swati Gupta, Ajay Goel

Twelve Chinese herbal preparations for the treatment of depression or depressive symptoms in cancer patients: a systematic review and meta-analysis of randomized controlled trials

Menglin Li, Zijie Chen, Zhenzhu Liu, Ning Zhang, Jintao Liu, Huiru Wang, Weiguang Wang, Yan Liang, Jingwen Chen, Zhe Liu, Yongle Li, Shuangqing Zhai

Critical pharmacokinetic and pharmacodynamic drug-herb interactions in rats between warfarin and pomegranate peel or guava leaves extracts

Maisa Alnaqeeb, Kenza A. Mansor, Eyad M. Mallah, Bayan Y. Ghanim, Nasir Idkaidek, Nidal A. Qinna

Protective effects of Camellia japonica flower extract against urban air pollutants

Minkyung Kim, Dahee Son, Seoungwoo Shin, Deokhoon Park, Sangyo Byun, Eunsun Jung

An oral toxicity test in rats and a genotoxicity study of extracts from the stems of Opuntia ficus-indica var. saboten

  • Open Access
  • Research article

Eun Hye Han, Mi Kyung Lim, Sang Ho Lee, Md. Mahbubur Rahman, Young-Hee Lim

The anti-proliferative effect of apricot and peach kernel extracts on human colon cancer cells in vitro

Wagheda Cassiem, Maryna de Kock

Bioassay-guided isolation of active anti-adipogenic compound from royal jelly and the study of possible mechanisms

Prakash Raj Pandeya, Ramakanta Lamichhane, Kyung-Hee Lee, Se-Gun Kim, Dae-Ho Lee, Hyeong-Kyu Lee, Hyun-Ju Jung

The activity of commercial antimicrobials, and essential oils and ethanolic extracts of Olea europaea on Streptococcus agalactiae isolated from pregnant women

Munyaradzi Mukesi, Benson C. Iweriebor, Larry C. Obi, Uchechukwu U. Nwodo, Sylvester R. Moyo, Anthony I. Okoh

Wu-Mei-wan protects pancreatic β cells by inhibiting NLRP3 Inflammasome activation in diabetic mice

Xueping Yang, Fuer Lu, Lingli Li, Jingbin Li, Jinlong Luo, Siyi Zhang, Xinqiao Liu, Guang Chen

Effect of Osteoking on the osteogenic and adipogenic differentiation potential of rat bone marrow mesenchymal stem cells in vitro

  • Open Access
  • Research article

Congtao Yu, Lifen Dai, Zhaoxia Ma, Hongbin Zhao, Yong Yuan, Yunfeng Zhang, Pengfei Bao, Yanfang Su, Daiping Ma, Change Liu, Xingfei Wu, Jinxue Liu, Yanjiao Li, Bing Wang, Min Hu

Antilisterial efficacy of Lactobacillus brevis MF179529 from cow: an in vivo evidence

Ayesha Riaz, Saleha Noureen, Iram Liqat, Muhammad Arshad, Najma Arshad

2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cells

Wuguo Li, Qing Zhang, Kaotan Chen, Zhenhua Sima, Jingli Liu, Qiang Yu, Jiawei Liu

Exercise and resveratrol increase fracture resistance in the 3xTg-AD mouse model of Alzheimer’s disease

Mustafa F. Alkhouli, Jun Hung, Michaela Squire, Miranda Anderson, Monica Castro, Jeganathan R. Babu, Layla Al-Nakkash, Tom L. Broderick, Jeffrey H. Plochocki

Anti-borreliae efficacy of selected organic oils and fatty acids

Anna Goc, Aleksandra Niedzwiecki, Matthias Rath

Effects of Radix Linderae extracts on a mouse model of diabetic bladder dysfunction in later decompensated phase

Xufeng Yang, Dawei Lian, Pinglong Fan, Yifei Xu, Jing Wang, Fangjun Chen, Huanling Lai, Weiwen Jiang, Linjie Zhang, Ping Huang, Hongying Cao

Decreased fracture incidence with traditional Chinese medicine therapy in patients with osteoporosis: a nationwide population-based cohort study

Yu-Chi Wang, Jen-Huai Chiang, Hsin-Cheng Hsu, Chun-Hao Tsai

Extracts from Sageretia thea reduce cell viability through inducing cyclin D1 proteasomal degradation and HO-1 expression in human colorectal cancer cells

Ha Na Kim, Gwang Hun Park, Su Bin Park, Jeong Dong Kim, Hyun Ji Eo, Ho-Jun Son, Jeong Ho Song, Jin Boo Jeong

Effect of freeze-dried Carica papaya leaf juice on inflammatory cytokines production during dengue virus infection in AG129 mice

Nor Azrina Norahmad, Mohd Ridzuan Mohd Abd Razak, Norazlan Mohmad Misnan, Nur Hana Md Jelas, Umi Rubiah Sastu, Amirrudin Muhammad, Tiffiny Chau Dee Ho, Bazilah Jusoh, Nor Azlina Zolkifli, Ravindran Thayan, Adiratna Mat Ripen, Murizal Zainol, Ami Fazlin Syed Mohamed

Potential in vitro anti-allergic, anti-inflammatory and cytotoxic activities of ethanolic extract of Baliospermum montanum root, its major components and a validated HPLC method

  • Open Access
  • Research article

Weerachai Pipatrattanaseree, Arunporn Itharat, Nichamon Mukkasombut, Ubonwan Saesiw

Improved antibacterial effects of alkali-transformed saponin from quinoa husks against halitosis-related bacteria

Xiaoyan Sun, Xiushi Yang, Peng Xue, Zhiguo Zhang, Guixing Ren

Crude extract from Libidibia ferrea (Mart. ex. Tul.) L.P. Queiroz leaves decreased intra articular inflammation induced by zymosan in rats

  • Open Access
  • Research article

Tamires Rocha Falcão, Cássio Alexandre Oliveira Rodrigues, Aurigena Antunes de Araújo, Caroline Addison Carvalho Xavier de Medeiros, Luiz Alberto Lira Soares, Magda Rhayanny Assunção Ferreira, Roseane Carvalho Vasconcelos, Raimundo Fernandes de Araújo Júnior, Maria Luiza Diniz de Sousa Lopes, Gerlane Coelho Bernardo Guerra

Multi-targeting chemoprevention of Chinese herb formula Yanghe Huayan decoction on experimentally induced mammary tumorigenesis

  • Open Access
  • Research article

Jingwei Li, Xiaofei Liu, Hongzhi Chen, Ziyuan Sun, Hanhan Chen, Lei Wang, Xiaohui Sun, Xiangqi Li

Protective effects of triple fermented barley extract (FBe) on indomethacin-induced gastric mucosal damage in rats

Jong-Min Lim, Chang-Hyun Song, Su-Jin Park, Dong-Chan Park, Go-Woon Jung, Hyung-Rae Cho, Khawaja Muhammad Imran Bashir, Sae Kwang Ku, Jae-Suk Choi

Synergistic study of a Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) combination on cell survival in EA.hy926 cells

  • Open Access
  • Research article

Xian Zhou, Valentina Razmovski-Naumovski, Antony Kam, Dennis Chang, Chun Guang Li, Kelvin Chan, Alan Bensoussan

Compounds from Olea europaea and Pistacia lentiscus inhibit oral microbial growth

Lamprini Karygianni, Manuel Cecere, Aikaterini Argyropoulou, Elmar Hellwig, Alexios Leandros Skaltsounis, Annette Wittmer, Jörg Philipp Tchorz, Ali Al-Ahmad

Antihypertensive effects of the hydro-ethanol extract of Senecio serratuloides DC in rats

Charlotte Mungho Tata, Constance Rufaro Sewani-Rusike, Opeoluwa Oyehan Oyedeji, Ephraim Tobela Gwebu, Fikile Mahlakata, Benedicta Ngwenchi Nkeh-Chungag

In vitro antioxidant and antiproliferative effect of the extracts of Ephedra chilensis K Presl aerial parts

  • Open Access
  • Research article

Marco Mellado, Mauricio Soto, Alejandro Madrid, Iván Montenegro, Carlos Jara-Gutiérrez, Joan Villena, Enrique Werner, Patricio Godoy, Luis F. Aguilar

Effects of resveratrol on Th17 cell-related immune responses under tacrolimus-based immunosuppression

Kyoung Chan Doh, Bo-Mi Kim, Kyoung Woon Kim, Byung Ha Chung, Chul Woo Yang

Effects of unaltered and bioconverted mulberry leaf extracts on cellular glucose uptake and antidiabetic action in animals

Sang-Hyuk Jung, Joo-Hui Han, Hyun-Soo Park, Do-Hyung Lee, Seok Jin Kim, Hyun So Cho, Jong Seong Kang, Chang-Seon Myung

Effect of fractioning on antibacterial activity of n-butanol fraction from Enantia chlorantha stem bark methanol extract

Rebeca Madeleine Ebelle Etame, Raymond Simplice Mouokeu, Frank Stève Monthe Poundeu, Igor Kenfack Voukeng, Cedric Laurel Pouaha Cidjeu, Alembert Tchinda Tiabou, Abel Joel Gbaweng Yaya, Rosalie Anne Ngono Ngane, Jules Roger Kuiate, François Xavier Etoa

Dual actions on gout flare and acute kidney injury along with enhanced renal transporter activities by Yokuininto, a Kampo medicine

  • Open Access
  • Gout
  • Research article

Seung Hoon Lee, Ho-Sung Lee, Gunhyuk Park, Sung-Man Oh, Dal-Seok Oh

Effectiveness and safety of electroacupuncture for poststroke patients with shoulder pain: study protocol for a double-center, randomized, patient- and assessor-blinded, sham-controlled, parallel, clinical trial

Seungwon Shin, Sung Pil Yang, Ami Yu, Junghee Yoo, Sung Min Lim, Euiju Lee

Green cardamom supplementation improves serum irisin, glucose indices, and lipid profiles in overweight or obese non-alcoholic fatty liver disease patients: a double-blind randomized placebo-controlled clinical trial

  • Open Access
  • Obesity
  • Research article

Milad Daneshi-Maskooni, Seyed Ali Keshavarz, Mostafa Qorbani, Siavash Mansouri, Seyed Moayed Alavian, Mahtab Badri-Fariman, Seyed Ali Jazayeri-Tehrani, Gity Sotoudeh

Manual therapy for the pediatric population: a systematic review

  • Open Access
  • Research article

Carol Parnell Prevost, Brian Gleberzon, Beth Carleo, Kristian Anderson, Morgan Cark, Katherine A. Pohlman

Acupuncture in improving endometrial receptivity: a systematic review and meta-analysis

Yajing Zhong, Fanzhu Zeng, Wanjun Liu, Jing Ma, Yongge Guan, Yang Song

Cancer patients’ use of complementary and alternative medicine in Sweden: a cross-sectional study

  • Open Access
  • Research article

Kathrin Wode, Roger Henriksson, Lena Sharp, Anna Stoltenberg, Johanna Hök Nordberg

Different training durations and styles of tai chi for glucose control in patients with type 2 diabetes: a systematic review and meta-analysis of controlled trials

Ting-Wei Xia, Yue Yang, Wei-Hong Li, Zhao-Hui Tang, Zong-Run Li, Li-Jun Qiao

Effects of a combination of herbal extracts (modified Ojayeonjonghwan (Wuzi Yanzong wan)) on partial urethral obstruction-induced detrusor overactivity in rats: impact on the nitric oxide pathway and oxidative stress

Sangrak Bae, Kyu Won Lee, Hyun Cheol Jeong, Bong Hee Park, Woong Jin Bae, Chang Hee Han, Sae Woong Kim

‘We are nothing without herbs’: a story of herbal remedies use during pregnancy in rural Ghana

  • Open Access
  • Research article

Prince Peprah, Williams Agyemang-Duah, Francis Arthur-Holmes, Hayford Isaac Budu, Emmanuel Mawuli Abalo, Reforce Okwei, Julius Nyonyo

Herbal medicine use during breastfeeding: a cross-sectional study among mothers visiting public health facilities in the Western area of Sierra Leone

Peter Bai James, Angela Isata Kaikai, Abdulai Jawo Bah, Amie Steel, Jon Wardle

Traditional Chinese medicine formulation Yanggan Jiedu Sanjie inhibits TGF-β1-induced epithelial-mesenchymal transition and metastatic potential in human hepatocarcinoma Bel-7402 cells

Bing Hu, Hong-Mei An, Xia Yan, Jia-Lu Zheng, Xiao-Wei Huang, Miao Li

The use of maoto (Ma-Huang-Tang), a traditional Japanese Kampo medicine, to alleviate flu symptoms: a systematic review and meta-analysis

Tetsuhiro Yoshino, Ryutaro Arita, Yuko Horiba, Kenji Watanabe

Announcing the affiliation between BMC Complementary and Alternative Medicine and Cochrane Complementary Medicine

  • Open Access
  • Editorial

L. Susan Wieland, Karen Pilkington, Liam J. Messin

Invitro synergistic activity of lactic acid bacteria against multi-drug resistant staphylococci

Jinal Bhola, Rama Bhadekar

Ocimum gratissimum Linn. Leaves reduce the key enzymes activities relevant to erectile dysfunction in isolated penile and testicular tissues of rats

Oluwafemi Adeleke Ojo, Adebola Busola Ojo, Babatunji Emmanuel Oyinloye, Basiru Olaitan Ajiboye, Omosola Olufisayo Anifowose, Ayodeji Akawa, Oluranti Esther Olaiya, Oluwaseun Ruth Olasehinde, Abidemi Paul Kappo

Effects of hydroalcoholic extract of Solidago chilensis Meyen on nociception and hypernociception in rodents

  • Open Access
  • Research article

Elena L. A. Malpezzi-Marinho, Graziela R. Molska, Lyvia I. G. P. Freire, Cristiane I. Silva, Eduardo K. Tamura, Laís F. Berro, Carlos A. Parada, Eduardo Ary Villela Marinho

A critical integrative review of complementary medicine education research: key issues and empirical gaps

  • Open Access
  • Research article

Alastair C. Gray, Amie Steel, Jon Adams

In vitro evaluation of the α-glucosidase inhibitory potential of methanolic extracts of traditionally used antidiabetic plants

  • Open Access
  • Research article

Astha Bhatia, Balbir Singh, Rohit Arora, Saroj Arora

Deciphering the mechanism of Indirubin and its derivatives in the inhibition of Imatinib resistance using a “drug target prediction-gene microarray analysis-protein network construction” strategy

Huayao Li, Lijuan Liu, Jing Zhuang, Cun Liu, Chao Zhou, Jing Yang, Chundi Gao, Gongxi Liu, Changgang Sun

Decreased risk of falls in patients attending music sessions on an acute geriatric ward: results from a retrospective cohort study

  • Open Access
  • Research article

Julia Chabot, Olivier Beauchet, Shek Fung, Isabelle Peretz

Immunomodulatory effects of a mycelium extract of Cordyceps (Paecilomyces hepiali; CBG-CS-2): a randomized and double-blind clinical trial

  • Open Access
  • Research article

Su-Jin Jung, Eun-Soo Jung, Eun-Kyung Choi, Hong-Sig Sin, Ki-Chan Ha, Soo-Wan Chae

Use and acceptance of complementary and alternative medicine among medical students: a cross sectional study from Palestine

  • Open Access
  • Research article

Ahmad M. Samara, Ethar R. Barabra, Hala N. Quzaih, Sa’ed H. Zyoud

Antinociceptive activity of petroleum ether fraction obtained from methanolic extract of Clinacanthus nutans leaves involves the activation of opioid receptors and NO-mediated/cGMP-independent pathway

Zainul Amiruddin Zakaria, Mohammad Hafiz Abdul Rahim, Mohd Hijaz Mohd Sani, Maizatul Hasyima Omar, Siew Mooi Ching, Arifah Abdul Kadir, Qamar Uddin Ahmed

Acute oral toxicity and antioxidant studies of an amine-based diselenide

  • Open Access
  • Research article

Mohammad Ibrahim, Niaz Muhammad, Musadiq Ibrahim, Muhammad Idrees Khan, Muhammad Ishaq Ali Shah, Muhammad Said, Waliullah Khan, Jean Paul Kamdem, Joao Batista Teixeira Rocha

Traditional Chinese medicine use is associated with lower end-stage renal disease and mortality rates among patients with diabetic nephropathy: a population-based cohort study

Hsing-Yu Chen, Heng-Chih Pan, Yung-Chang Chen, Yu-Chun Chen, Yi-Hsuan Lin, Sien-Hung Yang, Jiun-Liang Chen, Hau-Tieng Wu

Tannin profile, antioxidant properties, and antimicrobial activity of extracts from two Mediterranean species of parasitic plant Cytinus

  • Open Access
  • Research article

Giuseppantonio Maisetta, Giovanna Batoni, Pierluigi Caboni, Semih Esin, Andrea C. Rinaldi, Paolo Zucca

Alternative or complementary attitudes toward alternative and complementary medicines

  • Open Access
  • Research article

Fabrice Berna, Anja S. Göritz, Amaury Mengin, Renaud Evrard, Jacques Kopferschmitt, Steffen Moritz

Acute liver failure associated with Fructus Psoraleae: a case report and literature review

Ang Li, Minhong Gao, Na Zhao, Ping Li, Jinguo Zhu, Wenfei Li

What has been the impact of the Traditional Herbal Registration (THR) scheme in the UK on information provided with herbal products bought over the counter?

  • Open Access
  • Research article

R. Dickinson, M. C. Kennedy, D. K. Raynor, P. Knapp, M. Thomas, E. Adami

The modified Si-Jun-Zi Decoction attenuates colon cancer liver metastasis by increasing macrophage cells

Jin-Yong Zhou, Min Chen, Cun-En Wu, Yu-Wen Zhuang, Yu-Gen Chen, Shen-Lin Liu

Effects of whole-body ELECTROMYOSTIMULATION on health and performance: a systematic review

  • Open Access
  • Research article

Alvaro Pano-Rodriguez, Jose Vicente Beltran-Garrido, Vicenç Hernández-González, Joaquim Reverter-Masia

Superoxide-producing lipoprotein fraction from Stevia leaves: definition of specific activity

A. S. Isoyan, K. V. Simonyan, R. M. Simonyan, M. A. Babayan, G. M. Simonyan, V. A. Chavushyan, M. A. Simonyan

Differences in anti-inflammatory effect of immature and mature of Rubus coreanus fruits on LPS-induced RAW 264.7 macrophages via NF-κB signal pathways

Kyung Hye Seo, Ji Yeon Lee, Jeong-Yong Park, Gwi Yeong Jang, Hyung Don Kim, Young- Seob Lee, Dong Hwi Kim

Papaver nudicaule (Iceland poppy) alleviates lipopolysaccharide-induced inflammation through inactivating NF-κB and STAT3

Jae-Hyeon Oh, Miyong Yun, Dain Park, In Jin Ha, Chang-Kug Kim, Do-Wan Kim, Eun-Ok Kim, Seok-Geun Lee

Effect of Celastrus orbiculatus in inhibiting Helicobacter pylori induced inflammatory response by regulating epithelial mesenchymal transition and targeting miR-21/PDCD4 signaling pathway in gastric epithelial cells

Yaodong Zhu, Lei Liu, Lei Hu, Wenqing Dong, Mei Zhang, Yanqing Liu, Ping Li

The Alisma and Rhizoma decoction abates nonalcoholic steatohepatitis-associated liver injuries in mice by modulating oxidative stress and autophagy

Lijun Xu, Menghui Jing, Lijuan Yang, Lei Jin, Peiqiang Gong, Juan Lu, Hui Lin, Jinping Wang, Qin Cao, Yuanye Jiang

“Then I went to a hospital abroad”: acknowledging implications of stakeholders’ differing risk understandings related to use of complementary and alternative medicine in European health care contexts

Anita Salamonsen, Solveig Wiesener

Leaf extracts from Dendropanax morbifera Léveille mitigate mercury-induced reduction of spatial memory, as well as cell proliferation, and neuroblast differentiation in rat dentate gyrus

  • Open Access
  • Research article

Woosuk Kim, Dae Young Yoo, Hyo Young Jung, Jong Whi Kim, Kyu Ri Hahn, Hyun Jung Kwon, Miyoung Yoo, Sanghee Lee, Sung Min Nam, Yeo Sung Yoon, Dae Won Kim, In Koo Hwang

A cross-sectional assessment of knowledge, attitudes and self-perceived effectiveness of complementary and alternative medicine among pharmacy and non-pharmacy university students

  • Open Access
  • Massage
  • Research article

Mariam Ashraf, Hamid Saeed, Zikria Saleem, Hassaan Anwer Rathore, Fawad Rasool, Eman Tahir, Tooba Bhatti, Javeria Khalid, Iqra Bhatti, Ayesha Tariq

Supplemental thiamine for the treatment of acute heart failure syndrome: a randomized controlled trial

  • Open Access
  • Dyspnea
  • Research article

Howard A. Smithline, Michael Donnino, Fidela S. J. Blank, Richard Barus, Ryan A. Coute, Alexander B. Knee, Paul Visintainer

Evaluation of the effects of a standardized aqueous extract of Phyllanthus emblica fruits on endothelial dysfunction, oxidative stress, systemic inflammation and lipid profile in subjects with metabolic syndrome: a randomised, double blind, placebo controlled clinical study

Pingali Usharani, Padma Latha Merugu, Chandrasekhar Nutalapati

Hibiscus flower extract selectively induces apoptosis in breast cancer cells and positively interacts with common chemotherapeutics

Christopher Nguyen, Kiruthika Baskaran, Alaina Pupulin, Ivan Ruvinov, Ola Zaitoon, Sahibjot Grewal, Benjamin Scaria, Ali Mehaidli, Caleb Vegh, Siyaram Pandey

Water-soluble polyphenol-rich clove extract lowers pre- and post-prandial blood glucose levels in healthy and prediabetic volunteers: an open label pilot study

  • Open Access
  • Research article

Ratheesh Mohan, Svenia Jose, Johannah Mulakkal, Darla Karpinsky-Semper, Andrew G. Swick, I. M. Krishnakumar

Crude microcystins extracted from Microcystis aeruginosa exert anti-obesity effects by downregulating angiogenesis and adipogenesis related signaling molecules in HUVEC and 3 T3-L1 cells

  • Open Access
  • Obesity
  • Research article

Muhammad Imran Khan, Jin Hyuk Shin, Jong Deog Kim

Physalin A regulates the Nrf2 pathway through ERK and p38 for induction of detoxifying enzymes

  • Open Access
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Ji Min Shin, Kyung-Mi Lee, Hee Ju Lee, Ji Ho Yun, Chu Won Nho

Antibacterial activities of triterpenoidal compounds isolated from Calothamnus quadrifidus leaves

  • Open Access
  • Research article

H. A. Ibrahim, M. R. Elgindi, R. R. Ibrahim, D. G. El-Hosari

Chinese herbal bath therapy for the treatment of uremic pruritus: meta-analysis of randomized controlled trials

Wenxuan Xue, Yanhua Zhao, Mengyun Yuan, Zhiqiang Zhao

Bacillus/Trapa japonica Fruit Extract Ferment Filtrate enhances human hair follicle dermal papilla cell proliferation via the Akt/ERK/GSK-3β signaling pathway

Gun-He Nam, Kyung-Jo Jo, Ye-Seul Park, Hye Won Kawk, Je-Geun Yoo, Jin Dong Jang, Sang Moon Kang, Sang-Yong Kim, Young-Min Kim

Preclinical evaluation of safety and potential of black hellebore extracts for cancer treatment

  • Open Access
  • Research article

Jennifer E. Felenda, Claudia Turek, Nora Mörbt, Anja Herrick, Margit B. Müller, Florian C. Stintzing

Avoiding pitfalls in determining antimicrobial activity of plant extracts and publishing the results

Jacobus Nicolaas Eloff

Shen Shuai IIRecipe attenuates renal injury and fibrosis in chronic kidney disease by regulating NLRP3 inflammasome and Sirt1/Smad3 deacetylation pathway

Meng Wang, Liuyi Yang, Jing Yang, Chen Wang

Fractions and isolated compounds from Oxyanthus speciosus subsp. stenocarpus (Rubiaceae) have promising antimycobacterial and intracellular activity

Abimbola O. Aro, Jean P. Dzoyem, Maurice D. Awouafack, Mamoalosi A. Selepe, Jacobus N. Eloff, Lyndy J. McGaw

Neuroprotective effects of berberine in animal models of Alzheimer’s disease: a systematic review of pre-clinical studies

Ning-Ning Yuan, Cui-Zan Cai, Ming-Yue Wu, Huan-Xing Su, Min Li, Jia-Hong Lu

Lancemaside A, a major triterpene saponin of Codonopsis lanceolata enhances regulation of nitric oxide synthesis via eNOS activation

Young Seok Lee, HeeEun Kim, Jinhye Kim, Geun Hee Seol, Kwang-Won Lee

Salidroside protects against ox-LDL-induced endothelial injury by enhancing autophagy mediated by SIRT1-FoxO1 pathway

Zhongsheng Zhu, Jinyu Li, Xiaorong Zhang

Cytotoxic and cell cycle arrest properties of two steroidal alkaloids isolated from Holarrhena floribunda (G. Don) T. Durand & Schinz leaves

J. A. Badmus, O. E. Ekpo, A. A. Hussein, M. Meyer, D. C. Hiss

Alyssum homolocarpum seed oil (AHSO), containing natural alpha linolenic acid, stearic acid, myristic acid and β-sitosterol, increases proliferation and differentiation of neural stem cells in vitro

Reza Mahmoudi, Majid Ghareghani, Kazem Zibara, Maryam Tajali Ardakani, Yahya Jand, Hassan Azari, Jafar Nikbakht, Amir Ghanbari

Postbiotic metabolites produced by Lactobacillus plantarum strains exert selective cytotoxicity effects on cancer cells

  • Open Access
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Li-Oon Chuah, Hooi Ling Foo, Teck Chwen Loh, Noorjahan Banu Mohammed Alitheen, Swee Keong Yeap, Nur Elina Abdul Mutalib, Raha Abdul Rahim, Khatijah Yusoff

Characterization of burn wound healing gel prepared from human amniotic membrane and Aloe vera extract

  • Open Access
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Md Shaifur Rahman, Rashedul Islam, Md Masud Rana, Lucas-Sebastian Spitzhorn, Mohammad Shahedur Rahman, James Adjaye, Sikder M. Asaduzzaman

Potent antitumor property of Allium bakhtiaricum extracts

Kosar Vafaee, Soudeh Dehghani, Raheleh Tahmasvand, Farzaneh Saeed Abadi, Saeed Irian, Mona Salimi

Hepato-protective effects of Glossogyne tenuifolia in Streptozotocin-nicotinamide-induced diabetic rats on high fat diet

Shibu Marthandam Asokan, Ruoh-Yuh Wang, Tsu-Han Hung, Wan-Teng Lin

The effects of a hirudin/liposome complex on a diabetic nephropathy rat model

  • Open Access
  • Hirudin
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Hongwu Wang, Huantian Cui, Lan Lin, Yue Ji, Qing Ni, Junchen Li, Jianli Pang, Gongyan Bing, Yuhong Bian

Ouabain potentiates the antimicrobial activity of aminoglycosides against Staphylococcus aureus

Neelam Kumari, Snehlata Singh, Vandana Kumari, Siddhartha Kumar, Vinay Kumar, Antresh Kumar

Antibacterial and antibiotic-modifying activities of fractions and compounds from Albizia adianthifolia against MDR Gram-negative enteric bacteria

Cedric F. Tchinda, Gaiëlle Sonfack, Ingrid K. Simo, İlhami Çelik, Igor K. Voukeng, Blaise K. Nganou, Gabin T. M. Bitchagno, Sultan Funda Ekti, Mathieu Tene, Pierre Tane, Veronique P. Beng, Victor Kuete

Online yoga in myeloproliferative neoplasm patients: results of a randomized pilot trial to inform future research

  • Open Access
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Jennifer Huberty, Ryan Eckert, Amylou Dueck, Heidi Kosiorek, Linda Larkey, Krisstina Gowin, Ruben Mesa

Panax notoginseng saponins promote liver regeneration through activation of the PI3K/AKT/mTOR cell proliferation pathway and upregulation of the AKT/Bad cell survival pathway in mice

  • Open Access
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Hua Zhong, Hao Wu, He Bai, Menghao Wang, Jian Wen, Jianping Gong, Mingyong Miao, Fangchao Yuan

Inhibitory effects of Azadirachta indica secondary metabolites formulated cosmetics on some infectious pathogens and oxidative stress radicals

  • Open Access
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Sunday O. Okoh, Omobola O. Okoh, Anthony I. Okoh

Combining an in silico approach with an animal experiment to investigate the protective effect of troxerutin for treating acute lung injury

Ying Li, Pan Ma, Jin Fu, Jingjing Wu, Xue Wu

Mind-body practices for people living with HIV: a systematic scoping review

Maria Pilar Ramirez-Garcia, Marie-Pier Gagnon, Sébastien Colson, José Côté, Jorge Flores-Aranda, Myriam Dupont

Gut microbial modulation in the treatment of chemotherapy-induced diarrhea with Shenzhu Capsule

Jing Wang, Wuwen Feng, Shiyang Zhang, Lu Chen, Fei Tang, Yongcheng Sheng, Hui Ao, Cheng Peng

The protective effects of polysaccharide extract from Xin-Ji-Er-Kang formula on Ang II-induced HUVECs injury, L-NAME-induced hypertension and cardiovascular remodeling in mice

Ling Ding, Pan Cheng, Li Wang, Juan Hu, Yong-xue Zhang, Guo-wei Cai, Guang-yao Huang, Shan Gao

Modulation of neurological pathways by Salvia officinalis and its dependence on manufacturing process and plant parts used

  • Open Access
  • Opioids
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Carsten Tober, Roland Schoop

Curcumin as a permeability enhancer enhanced the antihyperlipidemic activity of dietary green tea extract

  • Open Access
  • Research article

Ashlesha P. Pandit, Shreyas R. Joshi, Preeti S. Dalal, Vinita C. Patole

Infrared-assisted extraction followed by high performance liquid chromatography to determine angoroside C, cinnamic acid, and harpagoside content in Scrophularia ningpoensis

  • Open Access
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Lina Su, Yinghui Deng, Nianzu Chen, Xiuwen Zhang, Taomin Huang

The effects of acupuncture on pregnancy outcomes of in vitro fertilization: a systematic review and meta-analysis

Zheng-yun Xie, Zhi-hang Peng, Bing Yao, Li Chen, Yan-yun Mu, Jie Cheng, Qian Li, Xi Luo, Peng-yan Yang, You-bing Xia

Cannabinoid-deficient Benin republic hemp (Cannabis sativa L.) improves semen parameters by reducing prolactin and enhancing anti-oxidant status

Abdullateef Isiaka Alagbonsi, Luqman Aribidesi Olayaki, Halimat Amin Abdulrahim, Thomson Sijuade Adetona, Gbemileke Tobiloba Akinyemi

Anti-tumor effect and mechanistic study of elemene on pancreatic carcinoma

Jin Long, Zhe Liu, Lian Hui

Calotropis gigantea extract induces apoptosis through extrinsic/intrinsic pathways and reactive oxygen species generation in A549 and NCI-H1299 non-small cell lung cancer cells

  • Open Access
  • NSCLC
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Jiyon Lee, Hui-Ju Jang, Hyunwoo Chun, Thu-Huyen Pham, Yesol Bak, Jong-Woon Shin, Hang Jin, Yong-In Kim, Hyung Won Ryu, Sei Ryang Oh, Do-Young Yoon

Effects of combined extracts of Lepidium meyenii and Allium tuberosum Rottl. on erectile dysfunction

Yi Zhang, Feixian Zhou, Fahuan Ge

Hypoglycemic effects of esculeoside A are mediated via activation of AMPK and upregulation of IRS-1

Ziming Yang, Li Zhang, Jinglei Liu, Fenglai Lu, Lei Wang, Yueyuan Chen, Dianpeng Li

Growth environment and organ specific variation in in-vitro cytoprotective activities of Picea mariana in PC12 cells exposed to glucose toxicity: a plant used for treatment of diabetes symptoms by the Cree of Eeyou Istchee (Quebec, Canada)

  • Open Access
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Ashleigh D. Downing, Hoda M. Eid, Andrew Tang, Fida Ahmed, Cory S. Harris, Pierre S. Haddad, Timothy Johns, John T. Arnason, Steffany A. L. Bennett, Alain Cuerrier

Inhibitory effects of oxymatrine on hepatic stellate cells activation through TGF-β/miR-195/Smad signaling pathway

  • Open Access
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Li-Ying Song, Yu-Tao Ma, Wei-Jin Fang, Yang He, Jia-Li Wu, Shan-Ru Zuo, Zhen-Zhen Deng, Sheng-Feng Wang, Shi-Kun Liu

ERK/Nrf2 pathway activation by caffeic acid in HepG2 cells alleviates its hepatocellular damage caused by t-butylhydroperoxide-induced oxidative stress

  • Open Access
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Sung-Yong Yang, Min Cheol Pyo, Mi-Hyun Nam, Kwang-Won Lee

Neutralization of cholera toxin by Rosaceae family plant extracts

  • Open Access
  • Cholera
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Magdalena Komiazyk, Malgorzata Palczewska, Izabela Sitkiewicz, Slawomir Pikula, Patrick Groves

Antibacterial and antibiofilm activity of acetone leaf extracts of nine under-investigated south African Eugenia and Syzygium (Myrtaceae) species and their selectivity indices

Ibukun M. Famuyide, Abimbola O. Aro, Folorunso O. Fasina, Jacobus N. Eloff, Lyndy J. McGaw

Mining the deep Red-Sea brine pool microbial community for anticancer therapeutics

Luke Esau, Guishan Zhang, Sunil Sagar, Ulrich Stingl, Vladimir B. Bajic, Mandeep Kaur

Laxative effects of triple fermented barley extracts (FBe) on loperamide (LP)-induced constipation in rats

Jong-Min Lim, Young Dae Kim, Chang-Hyun Song, Su-Jin Park, Dong-Chan Park, Hyung-Rae Cho, Go-Woon Jung, Khawaja Muhammad Imran Bashir, Sae Kwang Ku, Jae-Suk Choi

Effect of Moringa oleifera stem extract on hydrogen peroxide-induced opacity of cultured mouse lens

Lei Qi, Yu Zhou, Weijie Li, Mali Zheng, Ruisheng Zhong, Xin Jin, Yuan Lin

Antimicrobial activity of red wine and oenological extracts against periodontal pathogens in a validated oral biofilm model

María C. Sánchez, Honorato Ribeiro-Vidal, Adelaida Esteban-Fernández, Begoña Bartolomé, Elena Figuero, María V. Moreno-Arribas, Mariano Sanz, David Herrera

Chemical composition and bioactivity of essential oils and Ethanolic extracts of Ocimum basilicum L. and Thymus algeriensis Boiss. & Reut. from the Algerian Saharan Atlas

  • Open Access
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Maria Rezzoug, Boulanouar Bakchiche, Abdelaziz Gherib, Ascrizzi Roberta, FlaminiGuido, Özge Kilinçarslan, Ramazan Mammadov, Sanaa K. Bardaweel

Methanol extract of semen Ziziphi Spinosae attenuates ethanol withdrawal anxiety by improving neuropeptide signaling in the central amygdala

  • Open Access
  • Anxiety
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Li Bo Li, Young Woo Kim, Yu Hua Wang, Li Bai, Xiao Dong Zhu, Zheng Lin Zhao, Chul Won Lee, Yu Jiao, Tong Wu, Zhen Zhen Cai, Sang Chan Kim, Won G. An, Chae Ha Yang, Guang Cheng Cui, Rong Jie Zhao

Biological properties of Elaeagnus rhamnoides (L.) A. Nelson twig and leaf extracts

Bartosz Skalski, Bogdan Kontek, Bernadetta Lis, Beata Olas, Łukasz Grabarczyk, Anna Stochmal, Jerzy Żuchowski

In vitro anti-nephrotoxic potential of Ammi visnaga, Petroselinum crispum, Hordeum vulgare, and Cymbopogon schoenanthus seed or leaf extracts by suppressing the necrotic mediators, oxidative stress and inflammation

  • Open Access
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Marwa M. Abu-Serie, Noha H. Habashy, Adham M. Maher

Microbial, phytochemical, toxicity analyses and antibacterial activity against multidrug resistant bacteria of some traditional remedies sold in Buea Southwest Cameroon

Moses Njutain Ngemenya, Ghogo Gail Rinda Djeukem, Kennedy Dohjinga Nyongbela, Petuel Ndip Ndip Bate, Smith Borakaeyabe Babiaka, Elvis Monya, Rudolf Khundou Kanso

Costunolide induces mitochondria-mediated apoptosis in human gastric adenocarcinoma BGC-823 cells

Zhanpeng Yan, Tingting Xu, Zhentao An, Ying Hu, Wanzhen Chen, Jinxia Ma, Changle Shao, Fangshi Zhu

Safety assessment of the ethanolic extract of Gongronema latifolium Benth. leaves: a 90-day oral toxicity study in Sprague Dawley rats

  • Open Access
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Bassel Al-Hindi, Nor Adlin Yusoff, Mariam Ahmad, Item Justin Atangwho, Mohd Zaini Asmawi, Majed Ahmed Al-Mansoub, Yasser Mahfooth Tabana, Idris Bello, Mun Fei Yam

Biological and toxicological evaluation of Rhus trilobata Nutt. (Anacardiaceae) used traditionally in mexico against cancer

  • Open Access
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Luis Varela-Rodríguez, Blanca Sánchez-Ramírez, Ivette Stephanie Rodríguez-Reyna, José Juan Ordaz-Ortiz, David Chávez-Flores, Erika Salas-Muñoz, Juan Carlos Osorio-Trujillo, Ernesto Ramos-Martínez, Patricia Talamás-Rohana

Hepatoprotective effect of Solanum surattense leaf extract against chemical- induced oxidative and apoptotic injury in rats

Mohammad K. Parvez, Mohammed S. Al-Dosari, Ahmed H. Arbab, Perwez Alam, Mansour S. Alsaid, Azmat A. Khan

Icariin-conditioned serum engineered with hyaluronic acid promote repair of articular cartilage defects in rabbit knees

Juntao Zhang, Donglin Zhang, Chaochao Wu, Aifeng Liu, Chao Zhang, Jianjie Jiao, Man Shang

Qianggan extract improved nonalcoholic steatohepatitis by modulating lncRNA/circRNA immune ceRNA networks

  • Open Access
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Mingzhe Zhu, Meng Li, Wenjun Zhou, Yang Yang, Fenghua Li, Li Zhang, Guang Ji

Pharmacokinetics of cucurbitacin B from Trichosanthes cucumerina L. in rats

Natthaphon Hunsakunachai, Nitra Nuengchamnong, Weena Jiratchariyakul, Tanawan Kummalue, Phisit Khemawoot

Utilising network pharmacology to explore the underlying mechanism of Wumei Pill in treating pancreatic neoplasms

Yuxiang Wan, Lin Xu, Zeyu Liu, Ming Yang, Xin Jiang, Qiaoli Zhang, Jinchang Huang

Sub-acute and acute toxicity of Ferula asafoetida and Silybum marianum formulation and effect of the formulation on delaying gastric emptying

  • Open Access
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Ramanaiah Illuri, Sudeep Heggar Venkataramana, David Daguet, Shyamprasad Kodimule

Research trends in Korean medicine based on temporal and network analysis

Sang-Kyun Kim, Yongtaek Oh, SeJin Nam

Anti-cervical carcinoma effect of Portulaca oleracea L. polysaccharides by oral administration on intestinal dendritic cells

Rui Zhao, Xingyue Shao, Guiyan Jia, Yulan Huang, Zhe Liu, Bocui Song, Jinzuo Hou

Baltic amber teething necklaces: could succinic acid leaching from beads provide anti-inflammatory effects?

Michael D. Nissen, Esther T. L. Lau, Peter J. Cabot, Kathryn J. Steadman

Synthesized natural peptides from amphibian skin secretions increase the efficacy of a therapeutic vaccine by recruiting more T cells to the tumour site

Xuan Pan, Bowei Ma, Xinchao You, Shu Chen, Jialing Wu, Tianfang Wang, Shelley F. Walton, Jianwei Yuan, Xiaolian Wu, Guoqiang Chen, Yuejian Wang, Guoying Ni, Xiaosong Liu

Leaf extract of Caesalpinia mimosoides enhances oxidative stress resistance and prolongs lifespan in Caenorhabditis elegans

Panthakarn Rangsinth, Anchalee Prasansuklab, Chatrawee Duangjan, Xiaojie Gu, Krai Meemon, Michael Wink, Tewin Tencomnao

Rosmarinic acid improves hypertension and skeletal muscle glucose transport in angiotensin II-treated rats

Mujalin Prasannarong, Vitoon Saengsirisuwan, Juthamard Surapongchai, Jariya Buniam, Natsasi Chukijrungroat, Yupaporn Rattanavichit

Acute and repeated toxicological study of Myelophil, an ethanol extract of a mixture of Astragali Radix and Salviae Miltiorrhizae Radix, in beagle dogs

  • Open Access
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Jin-Yong Joung, Jin-Seok Lee, Jung-Hyo Cho, Dong-Soo Lee, Chang-Gue Son

The effects of Centella asiatica (L.) Urban on neural differentiation of human mesenchymal stem cells in vitro

  • Open Access
  • Research article

Norazzila Omar, Yogeswaran Lokanathan, Zainul Rashid Mohd Razi, Ruszymah Bt Haji Idrus

Anti-inflammatory effect of naringin and sericin combination on human peripheral blood mononuclear cells (hPBMCs) from patient with psoriasis

Raksawan Deenonpoe, Pokpong Prayong, Nattakarn Thippamom, Jitlada Meephansan, Kesara Na-Bangchang

Virucidal activity of Garcinia parvifolia leaf extracts in animal cell culture

  • Open Access
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Aziera Adnan, Zeenathul Nazariah Allaudin, Homayoun Hani, Hwei-San Loh, Teng-Jin Khoo, Kang Nee Ting, Rasedee Abdullah

What motivates new, established and long-term users of herbal medicine: is there more than push and pull?

  • Open Access
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Alexandra N. Welz, Agnes Emberger-Klein, Klaus Menrad

Evaluation of the anti-malarial activity of crude extract and solvent fractions of the leaves of Olea europaea (Oleaceae) in mice

  • Open Access
  • Malaria
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Desye Misganaw, Ephrem Engidawork, Teshome Nedi

Prevalence of, and factors associated with health supplement use in Dubai, United Arab Emirates: a population-based cross-sectional study

  • Open Access
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Naseem Mohammed Abdulla, Faisal Aziz, Iain Blair, Michal Grivna, Balazs Adam, Tom Loney

The mechanism and tumor inhibitory study of Lagopsis supine ethanol extract on colorectal cancer in nude mice

Lijuan Wei, Zhaoyong Wang, Yang Xia, Baichun Liu

Perspectives on the use of aromatherapy from clinicians attending an integrative medicine continuing education event

  • Open Access
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Amy C. S. Pearson, Susanne M. Cutshall, W. Michael Hooten, Nancy J. Rodgers, Brent A. Bauer, Anjali Bhagra

Royal jelly-derived proteins enhance proliferation and migration of human epidermal keratinocytes in an in vitro scratch wound model

  • Open Access
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Yan Lin, Qiqi Shao, Meng Zhang, Chenyue Lu, Joy Fleming, Songkun Su

The extract from Agkistrodon halys venom protects against lipopolysaccharide (LPS)-induced myocardial injury

Quan-Hai Wang, Wei Li, Yu-Xin Jiang, Xiao-Hua Lu, Guo-Guang Wang

Quercus infectoria gall extracts reduce quorum sensing-controlled virulence factors production and biofilm formation in Pseudomonas aeruginosa recovered from burn wounds

Akhter Ahmed Ahmed, Fraidoon Abdulqadir Salih

Evaluation of HuoXueHuaYu therapy for nonalcoholic fatty liver disease: a systematic review and meta-analysis of randomized controlled trial

Yunfei Cai, Qiuer Liang, Weihao Chen, Minghao Chen, Ruixue Chen, Yun Zhang, Ya Xiao, Liguo Chen

Pharmacy employees’ involvement in safeguarding persons with dementia who use dietary supplements: Results from a survey of Norwegian pharmacies

Hilde Risvoll, Frauke Musial, Kjell H. Halvorsen, Trude Giverhaug, Marit Waaseth

Butyrlycholine esterase inhibitory activity and effects of extracts (fruit, bark and leaf) from Zanthoxylum armatum DC in gut, airways and vascular smooth muscles

Fiaz Alam, Abdul Jabbar Shah

Comparison of pharmacological properties and phytochemical constituents of in vitro propagated and naturally occurring liverwort Lunularia cruciata

Sumira Mukhia, Palash Mandal, D. K. Singh, Devendra Singh

Evaluating the protective potency of Acacia hydaspica R. Parker on histological and biochemical changes induced by Cisplatin in the cardiac tissue of rats

Tayyaba Afsar, Suhail Razak, Ali Almajwal, Maria Shabbir, Muhammad Rashid Khan

Discovery, synthesis and antibacterial evaluation of phenolic compounds from Cylicodiscus gabunensis

  • Open Access
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Omar Aldulaimi, Falko Drijfhout, Fidelia I. Uche, Paul Horrocks, Wen-Wu Li

Bitter gourd (Momordica charantia) possess developmental toxicity as revealed by screening the seeds and fruit extracts in zebrafish embryos

  • Open Access
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Muhammad Farooq Khan, Nael Abutaha, Fahd A. Nasr, Ali S. Alqahtani, Omar M. Noman, Mohammad A. M. Wadaan

In vitro evaluation of methicillin-resistant and methicillin-sensitive Staphylococcus aureus susceptibility to Saudi honeys

  • Open Access
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Muhammad Barkaat Hussain, Yasser Mahmoud Kamel, Zia Ullah, Asif Ahmad Mohamad Jiman-Fatani, Ansar Shafiq Ahmad

Anti-inflammatory and nephroprotective activity of Juglans mollis against renal ischemia–reperfusion damage in a Wistar rat model

Jonathan Perez-Meseguer, Liliana Torres-González, Jorge Aurelio Gutiérrez-González, Gabriela Alarcón-Galván, Homero Zapata-Chavira, Noemi Waksman-de Torres, Diana Patricia Moreno-Peña, Linda Elsa Muñoz-Espinosa, Paula Cordero-Pérez

Efficacy and safety of Curcuma longa essential oil to inactivate hydatid cyst protoscoleces

Hossein Mahmoudvand, Mahbobeh Pakravanan, Mohammad Reza Aflatoonian, Amal Khudair Khalaf, Massumeh Niazi, Seyyed Reza Mirbadie, Amir Tavakoli Kareshk, Mehrdad Khatami

Study of the antitumor mechanisms of apiole derivatives (AP-02) from Petroselinum crispum through induction of G0/G1 phase cell cycle arrest in human COLO 205 cancer cells

Kuan-Hsun Wu, Wen-Jui Lee, Tzu-Chun Cheng, Hui-Wen Chang, Li-Ching Chen, Chia-Chang Chen, Hsiu-Man Lien, Teng-Nan Lin, Yuan-Soon Ho

Prenylated flavonoid-enriched fraction from Maclura tinctoria shows biological activity against Staphylococcus aureus and protects Galleria mellonella larvae from bacterial infection

  • Open Access
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Ayla das Chagas Almeida, Lais Azevedo Rodrigues, Graziela dos Santos Paulino, Ananda Pereira Aguilar, Alisson Andrade Almeida, Sukarno Olavo Ferreira, Geraldo Célio Brandão, João Paulo Viana Leite, Andréa de Oliveira Barros Ribon

Adverse effects of yoga: a national cross-sectional survey

  • Open Access
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Holger Cramer, Daniela Quinker, Dania Schumann, Jon Wardle, Gustav Dobos, Romy Lauche

Velvet antler polypeptide partially rescue facet joint osteoarthritis-like phenotype in adult β-catenin conditional activation mice

Wan-qing Xie, Yong-jian Zhao, Feng Li, Bing Shu, Shu-ru Lin, Li Sun, Yong-jun Wang, Hong-xin Zheng

Distal acupoint stimulation versus peri-incisional stimulation for postoperative pain in open abdominal surgery: a systematic review and implications for clinical practice

Juan Zhu, Qian Xu, Rong Zou, Wenzhong Wu, Xiaoqiu Wang, Yanyi Wang, Fangbing Ji, Zhen Zheng, Man Zheng

Wenshen Jianpi recipe, a blended traditional Chinese medicine, ameliorates proteinuria and renal injury in a rat model of diabetic nephropathy

Xiaodan Cao, Renxiong Wei, Jun Zhou, Xiaoxia Zhang, Wenbo Gong, Tinglong Jin, Xiabo Chen

Herbal remedies used for the treatment of infertility in males and females by traditional healers in the rural areas of the West Bank/Palestine

Nidal Jaradat, Abdel Naser Zaid

Effects of probiotic supplementation on post-infectious irritable bowel syndrome in rodent model

Ki-Bae Hong, Hyeyoung Seo, Joong-su Lee, Yooheon Park

Herbal supplements in the print media: communicating benefits and risks

  • Open Access
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Matthew Peacock, Mihaela Badea, Flavia Bruno, Lada Timotijevic, Martina Laccisaglia, Charo Hodgkins, Monique Raats, Bernadette Egan

Design and study of anticaries effect of different medicinal plants against S.mutans glucosyltransferase

  • Open Access
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Kiranmai Mandava, Uma Rajeswari Batchu, Shravya Kakulavaram, Shulamithi Repally, Ishwarya Chennuri, Srinivas Bedarakota, Namratha Sunkara

Triptolide attenuates lipopolysaccharide-induced inflammatory responses in human endothelial cells: involvement of NF-κB pathway

  • Open Access
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Chundong Song, Youping Wang, Lin Cui, Fengna Yan, Si Shen

Synergistic activity between Triphala and selected antibiotics against drug resistant clinical isolates

Amirthasingam Manoraj, Vasanthi Thevanesam, B. M. R. Bandara, Asela Ekanayake, Veranja Liyanapathirana

Evaluation of chemical constituents and in vitro antimicrobial, antioxidant and cytotoxicity potential of rhizome of Astilbe rivularis (Bodho-okhati), an indigenous medicinal plant from Eastern Himalayan region of India

Vijeta Rai, Anoop Kumar, Vaskar Das, Shilpi Ghosh

Self-directed learning and practice of Italian osteopathic students during summer break: a cross-sectional survey

  • Open Access
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Giandomenico D’Alessandro, Giacomo Consorti, Francesco Cerritelli

Influence of curcumin supplementation on metabolic and lipid parameters of people living with HIV/AIDS: a randomized controlled trial

Tatiane Andreza Lima Silva, Danielle Coutinho Medeiros, Gidyenne Christine Bandeira Silva Medeiros, Rafaela Catherine Silva Cunha Medeiros, Juliany de Souza Araújo, Jason Azevedo Medeiros, Marcela Abbott Galvao Ururahy, Ronaldo Vagner Thomatieli Santos, Radames Maciel Vitor Medeiros, Lucia Leite-Lais, Paulo Moreira Silva Dantas

The synergistic antitumor effect of Huaier combined with 5-Florouracil in human cholangiocarcinoma cells

Zhaoyu Fu, Kexin Ma, Bing Dong, Chongyu Zhao, Chi Che, Chengyong Dong, Rixin Zhang, Haibo Wang, Xiang Wang, Rui Liang

Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells

  • Open Access
  • NSCLC
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Zujun Que, Zhiyi Zhou, Bin Luo, Changsheng Dong, Yi Jiang, Hegen Li, Jianhui Tian

Therapeutic effects of hydro-alcoholic extract of Achillea wilhelmsii C. Koch on indomethacin-induced gastric ulcer in rats: a proteomic and metabolomic approach

Mehdi Koushki, Reyhaneh Farrokhi Yekta, Nasrin Amiri-Dashatan, Masoumeh Dadpay, Fatemeh Goshadrou

In vitro α-amylase inhibitory effect of TLC isolates of Aloe megalacantha baker and Aloe monticola Reynolds

Gebretsadkan Hintsa Tekulu, Ephrem Mebrahtu Araya, Hayelom Gebrekirstos Mengesha

Water extract of Cnidii Rhizoma suppresses RANKL-induced osteoclastogenesis in RAW 264.7 cell by inhibiting NFATc1/c-Fos signaling and prevents ovariectomized bone loss in SD-rat

Ka-Yeon Lee, Jae-Hyun Kim, Eun-Young Kim, Mijung Yeom, Hyuk-Sang Jung, Youngjoo Sohn

Reporting items for systematic reviews and meta-analyses of acupuncture: the PRISMA for acupuncture checklist

Xiaoqin Wang, Yaolong Chen, Yali Liu, Liang Yao, Janne Estill, Zhaoxiang Bian, Taixiang Wu, Hongcai Shang, Myeong Soo Lee, Dang Wei, Jinhui Tian, Bin Ma, Yongfeng Wang, Guihua Tian, Kehu Yang

Traditional tonifying polyherbal infusion, Jatu-Phala-Tiga, exerts antioxidant activities and extends lifespan of Caenorhabditis elegans

  • Open Access
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Palika Wetchakul, Jo Aan Goon, Ademola Ezekiel Adekoya, Opeyemi Joshua Olatunji, Sutticha Ruangchuay, Patcharawalai Jaisamut, Acharaporn Issuriya, Nongluk Kunworarath, Surasak Limsuwan, Sasitorn Chusri

An ethnobotanical study of medicinal plants used to treat skin diseases in northern Pakistan

  • Open Access
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Khafsa Malik, Mushtaq Ahmad, Muhammad Zafar, Riaz Ullah, Hafiz Majid Mahmood, Bushra Parveen, Neelam Rashid, Shazia Sultana, Syed Nasar Shah, Lubna

In vitro and in vivo effects of traditional Chinese medicine formula T33 in human breast cancer cells

Yu-Te Liu, Chao-Hsiang Hsiao, Bor-Show Tzang, Tsai-Ching Hsu

ETM-DB: integrated Ethiopian traditional herbal medicine and phytochemicals database

  • Open Access
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Lemessa Etana Bultum, Assefa Mussa Woyessa, Doheon Lee

Pharmacological properties of Centella asiatica hydrogel in accelerating wound healing in rabbits

  • Open Access
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Afnan Sh. Ahmed, Muhammad Taher, Uttam Kumar Mandal, Juliana Md Jaffri, Deny Susanti, Syed Mahmood, Zainul Amiruddin Zakaria

Antinociceptive activities of Artocarpus lacucha Buch-ham (Moraceae) and its isolated phenolic compound, catechin, in mice

Shanta Islam, Md. Shafiullah Shajib, Ridwan Bin Rashid, Mohammad Firoz Khan, Md. Abdullah Al-Mansur, Bidyut Kanti Datta, Mohammad Abdur Rashid

RETRACTED ARTICLE: Xiaoyaosan exerts antidepressant-like effects by regulating the functions of astrocytes and EAATs in the prefrontal cortex of mice

Yan Liu, Xiu-fang Ding, Xin-xing Wang, Xiao-juan Zou, Xiao-juan Li, Yue-yun Liu, Jie Li, Xiu-yun Qian, Jia-xu Chen

Berberine inhibits NLRP3 Inflammasome pathway in human triple-negative breast cancer MDA-MB-231 cell

Mingjiang Yao, Xiaodi Fan, Bo Yuan, Norio Takagi, Sai Liu, Xiao Han, Junguo Ren, Jianxun Liu

Withania somnifera (L.) Dunal ameliorates neurodegeneration and cognitive impairments associated with systemic inflammation

  • Open Access
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Muskan Gupta, Gurcharan Kaur

Antimicrobial characteristics of Berberine against prosthetic joint infection-related Staphylococcus aureus of different multi-locus sequence types

Jiaqi Tan, Jin Wang, Chuang Yang, Chongzun Zhu, Geyong Guo, Jin Tang, Hao Shen

Characterization of the anti-Staphylococcus aureus fraction from Penthorum chinense Pursh stems

  • Open Access
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Bin Ding, Qinchao Ding, Shun Zhang, Zhuo Jin, Zhaolei Wang, Songtao Li, Xiaobing Dou

The cytotoxic effect and glucose uptake modulation of Baeckea frutescens on breast cancer cells

S. H. Shahruzaman, M. F. Mustafa, S. Ramli, S. Maniam, S. Fakurazi, S. Maniam

Oxidative stress mediated by gyrophoric acid from the lichen Umbilicaria hirsuta affected apoptosis and stress/survival pathways in HeLa cells

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Michal Goga, Martin Kello, Maria Vilkova, Klaudia Petrova, Martin Backor, Wolfram Adlassnig, Ingeborg Lang

Cellular and molecular effects of Baccharis dracunculifolia D.C. and Plectranthus barbatus Andrews medicinal plant extracts on retinoid metabolism in the human hepatic stellate cell LX-2

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Caio Mateus da Silva, Flávio Henrique Caetano, Franco Dani Campos Pereira, Maria Aparecida Marin Morales, Kumiko Koibuchi Sakane, Karen C. M. Moraes

Comparing physicians’ and patients’ reporting on adverse reactions in randomized trials on acupuncture—a secondary data analysis

Thea Schwaneberg, Claudia M. Witt, Stephanie Roll, Daniel Pach

Evaluation of the in vitro effects of commercial herbal preparations significant in African traditional medicine on platelets

  • Open Access
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Mmamosheledi E. Mothibe, Christina P. Kahler-Venter, Elzbieta Osuch

Research trends of acupuncture therapy on insomnia in two decades (from 1999 to 2018):a bibliometric analysis

Wenya Pei, Rui Peng, Yuan Gu, Xiaohong Zhou, Jingwen Ruan

Comparative effectiveness of six Chinese herb formulas for acute exacerbation of chronic obstructive pulmonary disease: a systematic review and network meta-analysis

  • Open Access
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Shaonan Liu, Jing Chen, Jinhong Zuo, Jiaqi Lai, Lei Wu, Xinfeng Guo

Larrea divaricata Cav. aqueous extract and nordihydroguariaretic acid modulate oxidative stress in submandibular glands of diabetic rats: a buccal protective in diabetes

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Ignacio Peralta, Carla Marrassini, María Laura Barreiro Arcos, Graciela Cremaschi, María Rosario Alonso, Claudia Anesini

Jiang-Zhi granules decrease sensitivity to low-dose CCl4 induced liver injury in NAFLD rats through reducing endoplasmic reticulum stress

Lili Yang, Yan Zhou, Haiyan Song, Peiyong Zheng

How do pharmacists use and recommend vitamins, minerals, herbals and other dietary supplements?

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Srujitha Marupuru, David Rhys Axon, Marion K. Slack

Glucose-lowering and hypolipidemic activities of polysaccharides from Cordyceps taii in streptozotocin-induced diabetic mice

Ru-Ming Liu, Rong Dai, Yi Luo, Jian-Hui Xiao

Ethanol extract of asiasari radix preferentially induces apoptosis in G361 human melanoma cells by differential regulation of p53

Kwang-Ha Park, Jeong-Hae Choi, Yeon-Suk Song, Gyoo-Cheon Kim, Jin-Woo Hong

The effects of Pandanus amaryllifolius (Roxb.) leaf water extracts on fructose-induced metabolic syndrome rat model

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Nur Hidayah Reshidan, Suhaila Abd Muid, Norshalizah Mamikutty

Resveratrol induces apoptosis of benign prostatic hyperplasia epithelial cell line (BPH-1) through p38 MAPK-FOXO3a pathway

Chao Li, Wan-Li Hu, Meng-Xin Lu, Guan-Fa Xiao

#MindinBody - feasibility of vigorous exercise (Bikram yoga versus high intensity interval training) to improve persistent pain in women with a history of trauma: a pilot randomized control trial

Alison Flehr, Christopher Barton, Jan Coles, Stephen J. Gibson, Gavin W. Lambert, Elisabeth A. Lambert, Arup K. Dhar, John B. Dixon

Comparative pharmacokinetics of oxyresveratrol alone and in combination with piperine as a bioenhancer in rats

Dhirarin Junsaeng, Tosapol Anukunwithaya, Phanit Songvut, Boonchoo Sritularak, Kittisak Likhitwitayawuid, Phisit Khemawoot

In vivo assessment of anticoagulant and antiplatelet effects of Syzygium cumini leaves extract in rabbits

Ahad Abdul Rehman, Azra Riaz, Muhammad Arif Asghar, Muhammad Liaquat Raza, Shadab Ahmed, Kamran Khan

Inhibitory effect of purple rice husk extract on AFB1-induced micronucleus formation in rat liver through modulation of xenobiotic metabolizing enzymes

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Arpamas Chariyakornkul, Charatda Punvittayagul, Sirinya Taya, Rawiwan Wongpoomchai

Modulation of cancer signalling pathway(s) in two -stage mouse skin tumorigenesis by annonacin

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Mohd Rohaizad Md Roduan, Roslida Abd Hamid, Norhafizah Mohtarrudin

The therapeutic effects of qigong in patients with chronic obstructive pulmonary disease in the stable stage: a meta-analysis

Hongxuan Tong, Yihua Liu, Yutian Zhu, Boli Zhang, Jingqing Hu

Baihe Zhimu formula attenuates the efficacy of tamoxifen against breast cancer in mice through modulation of CYP450 enzymes

Hailong Li, Chunyu Wu, Yu Liu, Shuo Zhang, Xiufei Gao

Solid state fermentation process with Aspergillus kawachii enhances the cancer-suppressive potential of silkworm larva in hepatocellular carcinoma cells

Hyun-Dong Cho, Hye-Ji Min, Yeong-Seon Won, Hee-Young Ahn, Young-Su Cho, Kwon-Il Seo

Cyanidin-3-rutinoside acts as a natural inhibitor of intestinal lipid digestion and absorption

Thavaree Thilavech, Sirichai Adisakwattana

Novel discovery of Averrhoa bilimbi ethanolic leaf extract in the stimulation of brown fat differentiation program in combating diet-induced obesity

  • Open Access
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Wai Kwan Lau, Nur Adelina Ahmad Noruddin, Abdul Hadi Ariffin, Muhd Zulkarnain Mahmud, Mohd Hasnan Mohd Noor, Azimah Amanah, Mohamad Faiz Hamzah, Zainuddin Zafarina

The protective effect and mechanism of catalpol on high glucose-induced podocyte injury

Yan Chen, Qingpu Liu, Zengfu Shan, Yingying Zhao, Meng Li, Baiyan Wang, Xiaoke Zheng, Weisheng Feng

Variation in the metabolites and α-glucosidase inhibitory activity of Cosmos caudatus at different growth stages

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Wan Ahmad Wan-Nadilah, Muhammad Tayyab Akhtar, Khozirah Shaari, Alfi Khatib, Azizah Abdul Hamid, Muhajir Hamid

Anti-obesity effect of Yangkyuksanwha-tang in high-fat diet-induced obese mice

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Young-Mee Koh, Soon-Woo Jang, Taek-Won Ahn

Microbial population dynamics under microdoses of the essential oil arborvitae

Rhegan C. McGregor, Kory A. Parker, Jacob M. Hornby, Leigh C. Latta IV

Intramuscular autologous blood therapy - a systematic review of controlled trials

Katja Oomen-Welke, Roman Huber

Evaluation of antimicrobial activity of chondrillasterol isolated from Vernonia adoensis (Asteraceae)

Winnie Mozirandi, Dexter Tagwireyi, Stanley Mukanganyama

Parental satisfaction and perception of Progress in influencing the Practice of complementary health approaches in children with autism: a cross sectional survey from Negeri Sembilan, Malaysia

Jun Jean Ong

The impact of uncertainty in society on the use of traditional, complementary and alternative medicine: a comparative study on visits to alternative/traditional/folk health care practitioners

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Jimpei Misawa, Rie Ichikawa, Akiko Shibuya, Yukihiro Maeda, Ichiro Arai, Teruyoshi Hishiki, Yoshiaki Kondo

A biological extract of turmeric (Curcuma longa) modulates response of cartilage explants to lipopolysaccharide

Wendy Pearson, Laima S. Kott

Investigation of Brassica juncea, Forsythia suspensa, and Inula britannica: phytochemical properties, antiviral effects, and safety

Won-Young Bae, Hyeong-Yeop Kim, Kyoung-Sook Choi, Kyung Hoon Chang, Young-Ho Hong, Jongsu Eun, Na-Kyoung Lee, Hyun-Dong Paik

Topical hydrogel containing Fumaria vaillantii Loisel. extract enhances wound healing in rats

Fatemeh Davoodi-Roodbordeii, Minoo Afshar, Fatemeh Haji Abas Tabrizi, Samira Choopani, Giti Torkaman, Fariborz Moayer, Mona Salimi

Diosgenin ameliorates palmitic acid-induced lipid accumulation via AMPK/ACC/CPT-1A and SREBP-1c/FAS signaling pathways in LO2 cells

Ke Fang, Fan Wu, Guang Chen, Hui Dong, Jingbin Li, Yan Zhao, Lijun Xu, Xin Zou, Fuer Lu

Phytochemical, in-vitro biological and chemo-preventive profiling of Arisaema jacquemontii Blume tuber extracts

Saira Tabassum, Muhammad Zia, Esperanza J. Carcahe de Blanco, Riffat Batool, Roohi Aslam, Sajid Hussain, Qamar Wali, Muhammad Mudassar Gulzar

The synergism of Clinacanthus nutans Lindau extracts with gemcitabine: downregulation of anti-apoptotic markers in squamous pancreatic ductal adenocarcinoma

Ling-Wei Hii, Swee-Hua Erin Lim, Chee-Onn Leong, Swee-Yee Chin, Ngai-Paing Tan, Kok-Song Lai, Chun-Wai Mai

Herbal or traditional medicine consumption in a Thai worker population: pattern of use and therapeutic control in chronic diseases

Napatt Kanjanahattakij, Pakakrong Kwankhao, Prin Vathesatogkit, Nisakron Thongmung, Yingampa Gleebbua, Piyamitr Sritara, Chagriya Kitiyakara

An exploration of healthcare providers’ experiences and perspectives of Traditional and complementary medicine usage and disclosure by Indigenous cancer patients

  • Open Access
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A. Gall, K. Anderson, J. Adams, V. Matthews, G. Garvey

Anti-viral activity of culinary and medicinal mushroom extracts against dengue virus serotype 2: an in-vitro study

Kavithambigai Ellan, Ravindran Thayan, Jegadeesh Raman, Kazuya I. P. J. Hidari, Norizah Ismail, Vikineswary Sabaratnam

Efficacy evaluation of ethanolic extract of Tamarindus indica L. leaves as possible alternate therapy in septic arthritis model of rabbit

Bishnu Prasad Sinha, Souvick Chatterjee, Rinku Buragohain, Indranil Samanta, Siddhartha Narayan Joardar, Prasenjit Mukherjee, Asit Kumar Maji, Partha Das, Tapan Kumar Mandal, Tapas Kumar Sar

Anti-inflammatory activities of astringent persimmons (Diospyros kaki Thunb.) stalks of various cultivar types based on the stages of maturity in the Gyeongnam province

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Jieun Choi, Mi Jeong Kim, Richard Komakech, Haiyoung Jung, Youngmin Kang

Anti-inflammatory activity of Jefea gnaphalioides (a. gray), Astereaceae

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Axel Villagómez-Rodríguez, Julia Pérez-Ramos, Ana Laura Esquivel-Campos, Cuauhtémoc Pérez-González, Claudia Angélica Soto-Peredo, Salud Pérez-Gutiérrez

Acteoside inhibits inflammatory response via JAK/STAT signaling pathway in osteoarthritic rats

Zhiguang Qiao, Jiaxin Tang, Wen Wu, Jian Tang, Ming Liu

Carica papaya extract in dengue: a systematic review and meta-analysis

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Senaka Rajapakse, Nipun Lakshitha de Silva, Praveen Weeratunga, Chaturaka Rodrigo, Chathurani Sigera, Sumadhya Deepika Fernando

Iranian propolis efficiently inhibits growth of oral streptococci and cancer cell lines

Fariba Asgharpour, Ali Akbar Moghadamnia, Ebrahim Zabihi, Sohrab Kazemi, Amirmorteza Ebrahimzadeh Namvar, Hemmat Gholinia, Mina Motallebnejad, Hamid Reza Nouri

Coix seed oil ameliorates cancer cachexia by counteracting muscle loss and fat lipolysis

Huiquan Liu, Lu Li, Jun Zou, Ting Zhou, Bangyan Wang, Huihui Sun, Shiying Yu

Immunosuppressive effect of hispidulin in allergic contact dermatitis

Premrutai Thitilertdecha, Panwadee Pluangnooch, Sunita Timalsena, Kitipong Soontrapa

Puerarin inhibits the osteoclastogenesis by inhibiting RANKL-dependent and –independent autophagic responses

Guoyou Zhang, Yu Wang, Guoke Tang, Yuanzheng Ma

A phytosterol-enriched saw palmetto supercritical CO2 extract ameliorates testosterone-induced benign prostatic hyperplasia by regulating the inflammatory and apoptotic proteins in a rat model

Heggar V. Sudeep, Karempudi Venkatakrishna, Ballal Amrutharaj, Anitha, Kodimule Shyamprasad

Chemical composition, antibacterial activity and related mechanism of valonia and shell from Quercus variabilis Blume (Fagaceae) against Salmonella paratyphi a and Staphylococcus aureus

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Dan Zhou, Ze-Hua Liu, Dong-Mei Wang, Deng-Wu Li, Li-Na Yang, Wei Wang

The protective effect of Phellinus linteus decoction on podocyte injury in the kidney of FSGS rats

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Feng Wan, Ru-chun Yang, Yan-peng Shi, Yue-Wen Tang, Xuan-li Tang, Xiao-ling Zhu, You-gui Li, Yong-jun Wang

Investigation of anti-cancer and migrastatic properties of novel curcumin derivatives on breast and ovarian cancer cell lines

Jinsha Koroth, Snehal Nirgude, Shweta Tiwari, Vidya Gopalakrishnan, Raghunandan Mahadeva, Sujeet Kumar, Subhas S. Karki, Bibha Choudhary

Ethanol extract of Chrysanthemum zawadskii Herbich induces autophagy and apoptosis in mouse colon cancer cells through the regulation of reactive oxygen species

Kwang-Youn Kim, Tae-Woo Oh, Hye-Jin Yang, Young-Woo Kim, Jin-Yeul Ma, Kwang-Il Park

Antioxidant and Cytoprotective effects of Pyrola decorata H. Andres and its five phenolic components

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Ban Chen, Xican Li, Jie Liu, Wei Qin, Minshi Liang, Qianru Liu, Dongfeng Chen

Heavy metal content of herbal health supplement products in Dubai – UAE: a cross-sectional study

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Naseem Mohammed Abdulla, Balazs Adam, Iain Blair, Abderrahim Oulhaj

Application evaluation of clinical practice guidelines for traditional Chinese medicine: a clinical analysis based on the analytic hierarchy process

  • Open Access
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Huayang Cai, Hui Li, Huizhen Zeng, Danping Xu, Wenwei Ouyang, Aiping Lv

Glucose and lipid lowering effects of Enhydra fluctuans extract in cadmium treated normal and type-2 diabetic model rats

Mohammad Nazmul Hasan, Farah Sabrin, Begum Rokeya, Md Shahinul Haque Khan, Mahtab Uddin Ahmed, Abel Matondo, Md Morsaline Billah, Salima Akter

Cyathea gigantea (Cyatheaceae) as an antimicrobial agent against multidrug resistant organisms

Kathakali Nath, Anupam Das Talukdar, Mrinal Kanti Bhattacharya, Deepshikha Bhowmik, Shiela Chetri, Debarati Choudhury, Abhijit Mitra, Nargis Alom Choudhury

Curcumin ameliorates peritoneal fibrosis via inhibition of transforming growth factor-activated kinase 1 (TAK1) pathway in a rat model of peritoneal dialysis

Jun-Li Zhao, Ting Zhang, Xia Shao, Jun-Jun Zhu, Mei-Zi Guo

Evaluation of the anti-cancer potential of Cedrus deodara total lignans by inducing apoptosis of A549 cells

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Xiaofeng Shi, Ruiqin Du, Junmin Zhang, Yanping Lei, Hongyun Guo

Efficacy of acupuncture in the management of post-apoplectic aphasia: a systematic review and meta-analysis of randomized controlled trials

He-yong Tang, Wei Tang, Feng Yang, Wei-wei Wu, Guo-ming Shen

Protein hydrolysate from potato confers hepatic-protection in hamsters against high fat diet induced apoptosis and fibrosis by suppressing Caspase-3 and MMP2/9 and by enhancing Akt-survival pathway

  • Open Access
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Shibu Marthandam Asokan, Tsu-Han Hung, Zong-Yan Li, Wen-Dee Chiang, Wan-Teng Lin

Anti-inflammatory and cytotoxic activities of the extracts, fractions, and chemical constituents isolated from Luehea ochrophylla Mart

Clináscia Rodrigues Rocha Araújo, Thiago de Melo Silva, Michaelle Geralda dos Santos, Marcelo Henrique Fernandes Ottoni, Elaine Maria de Souza Fagundes, Humberto de Sousa Fontoura, Gustavo Eustáquio Brito Alvim de Melo, Antônio Flávio de Carvalho Alcântara

Biological safety of Electroacupuncture with STS316 needles

Kwang-Ho Choi, Sun Hee Yeon, Seong Jin Cho, O Sang Kwon, Sanghun Lee, Su Yeon Seo, Suk-Yun Kang, Yeonhee Ryu

Protective effects of Oxya chinensis sinuosa Mishchenko against ultraviolet B-induced photodamage in hairless mice

A-Rang Im, InWha Park, Kon-Young Ji, Joo Young Lee, Ki Mo Kim, MinKyun Na, Sungwook Chae

Sinensetin regulates age-related sarcopenia in cultured primary thigh and calf muscle cells

Jin-A Kim, Seong Min Kim, Sang Eun Ha, Preethi Vetrivel, Venu Venkatarame Gowda Saralamma, Eun Hee Kim, Gon Sup Kim

Phytochemical composition of wormwood (Artemisia gmelinii) extracts in respect of their antimicrobial activity

Aliya S. Mamatova, Izabela Korona-Glowniak, Krystyna Skalicka-Woźniak, Aleksandra Józefczyk, Krzysztof K. Wojtanowski, Tomasz Baj, Zuriyadda B. Sakipova, Anna Malm

Remarkable rutin-rich Hypericum capitatum extract exhibits anti-inflammatory effects on turpentine oil-induced inflammation in rats

Anca D. Farcas, Augustin C. Mot, Cezara Zagrean-Tuza, Madalina Ticolea, Bogdan Sevastre, Muhittin Kulak, Radu Silaghi-Dumitrescu, Alina Parvu

Effect of Nigella sativa and its bioactive compound on type 2 epithelial to mesenchymal transition: a systematic review

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Abid Nordin, Haziq Kamal, Muhammad Dain Yazid, Aminuddin Saim, Ruszymah Idrus

Anti-inflammatory effect of Vaccinium oldhamii stems through inhibition of NF-κB and MAPK/ATF2 signaling activation in LPS-stimulated RAW264.7 cells

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Ha Na Kim, Jueng Kyu Baek, Su Bin Park, Jeong Dong Kim, Ho-Jun Son, Gwang Hun Park, Hyun Ji Eo, Jae Ho Park, Hyuk-Sang Jung, Jin Boo Jeong

Bryophyllum pinnatum enhances the inhibitory effect of atosiban and nifedipine on human myometrial contractility: an in vitro study

S. Santos, C. Haslinger, M. Mennet, U. von Mandach, M. Hamburger, A. P. Simões-Wüst

The fallacy of enzymatic hydrolysis for the determination of bioactive curcumin in plasma samples as an indication of bioavailability: a comparative study

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Sidney J. Stohs, C. Y. O. Chen, Harry G. Preuss, Sidhartha D. Ray, Luke R. Bucci, Jin Ji, Kevin J. Ruff

The potential of antioxidant-rich Maoberry (Antidesma bunius) extract on fat metabolism in liver tissues of rats fed a high-fat diet

Chattraya Ngamlerst, Arunwan Udomkasemsab, Ratchanee Kongkachuichai, Karunee Kwanbunjan, Chaowanee Chupeerach, Pattaneeya Prangthip

Identification and characterization of the Cucurbitacins, a novel class of small-molecule inhibitors of Tropomyosin receptor kinase a

Yueling Zhong, Hong Xu, Yi Zhong, Xuemiao Zhang, Ting Zeng, Limei Li, Gaojie Xu, Minhui Li, Jin Liu, Tai Yang

Isolation of bioactive compounds from Bergenia ciliata (haw.) Sternb rhizome and their antioxidant and anticholinesterase activities

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Roheena Zafar, Habib Ullah, Muhammad Zahoor, Abdul Sadiq

Characterization, evaluation of nutritional parameters of Radix isatidis protein and its antioxidant activity in D-galactose induced ageing mice

  • Open Access
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Ping Xiao, Hongzhi Huang, Xiang Li, Jianwei Chen, Jin-ao Duan

In vitro and in silico anti-dengue activity of compounds obtained from Psidium guajava through bioprospecting

Andrea Isabel Trujillo-Correa, Diana Carolina Quintero-Gil, Fredyc Diaz-Castillo, Winston Quiñones, Sara M. Robledo, Marlen Martinez-Gutierrez

Placebo design in WHO-registered trials of Chinese herbal medicine need improvements

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Xuan Zhang, Ran Tian, Chen Zhao, Xudong Tang, Aiping Lu, Zhaoxiang Bian

Treatment satisfaction in Chinese medicine outpatient care: a comparison of patients’ and doctors’ views

  • Open Access
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Yanhong Zhang, Jiqian Fang, Wei Gao, Ying Han, Runshun Zhang, Liyun He, Baoyan Liu

Complementary and alternative medicine use among infertile women attending infertility specialty clinics in South Korea: does perceived severity matter?

Jung Hye Hwang, Yi Young Kim, Hyea Bin Im, Dongwoon Han

Correction to: Acacia hydaspica R. Parker ameliorates cisplatin induced oxidative stress, DNA damage and morphological alterations in rat pulmonary tissue

  • Open Access
  • Correction

Tayyaba Afsar, Suhail Razak, Ali Almajwal, Muhammad Rashid Khan

Determination of the effects of cinnamon bark fractions on Candida albicans and oral epithelial cells

Marie-Pier Veilleux, Daniel Grenier

Total saponins of Bolbostemma paniculatum (maxim.) Franquet exert antitumor activity against MDA-MB-231 human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway

Jian-Wei Dou, Rong-Guo Shang, Xiao-Qin Lei, Kang-Le Li, Zhan-Zi Guo, Kai Ye, Xiao-Juan Yang, Yu-Wei Li, Yun-Yun Zhou, Jia Yao, Qian Huang

Prevalence, and health- and sociodemographic associations for visits to traditional and complementary medical providers in the seventh survey of the Tromsø study

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Agnete E. Kristoffersen, Ann Ragnhild Broderstad, Frauke Musial, Trine Stub

Sedative and hypnotic effects of compound Anshen essential oil inhalation for insomnia

Yu Zhong, Qin Zheng, Pengyi Hu, Xiaoying Huang, Ming Yang, Guilin Ren, Qing Du, Jun Luo, Kenan Zhang, Jing Li, Haixia Wu, Yuanyuan Guo, Shanshan Liu

Studies on antidiarrheal and laxative activities of aqueous-ethanol extract of Asphodelus tenuifolius and underlying mechanisms

Naveed Aslam, Khalid Hussain Janbaz

Antimicrobial and antibiofilm activities of Casearia sylvestris extracts from distinct Brazilian biomes against Streptococcus mutans and Candida albicans

Sabrina M. Ribeiro, Érick D. O. Fratucelli, Paula C. P. Bueno, Marlene Kelly V. de Castro, Amanda Alcalá Francisco, Alberto José Cavalheiro, Marlise I. Klein

Sheng Mai San protects H9C2 cells against hyperglycemia-induced apoptosis

Bing Pang, Li-Wei Shi, Li-juan Du, Yun-Chu Li, Mei-Zhen Zhang, Qing Ni

Heracleum moellendorffii roots inhibit the production of pro-inflammatory mediators through the inhibition of NF-κB and MAPK signaling, and activation of ROS/Nrf2/HO-1 signaling in LPS-stimulated RAW264.7 cells

  • Open Access
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Ha Na Kim, Jeong Dong Kim, Joo Ho Yeo, Ho-Jun Son, Su Bin Park, Gwang Hun Park, Hyun Ji Eo, Jin Boo Jeong

Comparative efficacy of pharmacological and nonpharmacological treatments for chronic idiopathic constipation in China: a Bayesian network meta-analysis

Qingyang Shi, Lizi Tan, Chunxiang Liu, Huijun Wang, Junhua Zhang, Hui Wang, Jingbo Zhai

Coix lacryma-jobi var. ma-yuen Stapf sprout extract induces cell cycle arrest and apoptosis in human cervical carcinoma cells

Eun Suk Son, Se-Hee Kim, Young Ock Kim, Young Eun Lee, Sun Young Kyung, Sung Hwan Jeong, Yu Jin Kim, Jeong-Woong Park

Antiaging effect of a Jianpi-yangwei formula in Caenorhabditis elegans

Liling Zeng, Zhimin Yang, Tianchan Yun, Shaoyi Fan, Zhong Pei, Ziwen Chen, Chen Sun, Fuping Xu

Inhibitory effects of berberine on proinflammatory M1 macrophage polarization through interfering with the interaction between TLR4 and MyD88

Jing Gong, Jingbin Li, Hui Dong, Guang Chen, Xin Qin, Meilin Hu, Fen Yuan, Ke Fang, Dingkun Wang, Shujun Jiang, Yan Zhao, Wenya Huang, Zhaoyi Huang, Fuer Lu

Antibacterial activities, proposed mode of action and cytotoxicity of leaf extracts from Triumfetta welwitschii against Pseudomonas aeruginosa

Molly Mombeshora, Stanley Mukanganyama

Inhibition of airway remodeling and inflammatory response by Icariin in asthma

Lingli Hu, Lulu Li, Hongying Zhang, Qiuping Li, Shan Jiang, Jian Qiu, Jing Sun, Jingcheng Dong

Protective effect of Shenmai injection on doxorubicin-induced cardiotoxicity via regulation of inflammatory mediators

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Sheng Zhang, Zhen-Qiang You, Lin Yang, Li-Li Li, You-Ping Wu, Li-Qiang Gu, Yan-Fei Xin

RETRACTED ARTICLE: Weipiling ameliorates gastric precancerous lesions in Atp4a−/− mice

Wei Liu, Zi-ming Zhao, Yuan-liang Liu, Hua-feng Pan, Li-zhu Lin

Inhibitory effects of ChondroT and its constituent herbs on RANKL-induced osteoclastogenesis

  • Open Access
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Rui Hong Guo, Seon-Jong Kim, Chan-hun Choi, Chang-su Na, Bok Yun Kang, Young Ran Kim

Qingkailing injection ameliorates cerebral ischemia-reperfusion injury and modulates the AMPK/NLRP3 Inflammasome Signalling pathway

  • Open Access
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Chongyang Ma, Xueqian Wang, Tian Xu, Xue Yu, Shuang Zhang, Shuling Liu, Yushan Gao, Shuning Fan, Changxiang Li, Changming Zhai, Fafeng Cheng, Qingguo Wang

Development and validation of traditional & complementary medicine (TCM) scales for nurses: Using structural equation modelling (SEM)

  • Open Access
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Hsiao-Yun Chang, Chia-Lun Lo, Yun-Ying Hung

Immuno-enhancement effects of Platycodon grandiflorum extracts in splenocytes and a cyclophosphamide-induced immunosuppressed rat model

Eun-Mi Noh, Jeong-Mi Kim, Hak Yong Lee, Hyun-Kyung Song, Sang Ok Joung, Hye Jeong Yang, Min Jung Kim, Kang Sung Kim, Young-Rae Lee

Anti-acne vulgaris effect including skin barrier improvement and 5α-reductase inhibition by tellimagrandin I from Carpinus tschonoskii

Jun Yin, In Hyoek Hwang, Min Won Lee

The effects of Berberis vulgaris consumption on plasma levels of IGF-1, IGFBPs, PPAR-γ and the expression of angiogenic genes in women with benign breast disease: a randomized controlled clinical trial

Saeed Pirouzpanah, Sanaz Asemani, Ali Shayanfar, Behzad Baradaran, Vahid Montazeri

Cartilage protective and anti-analgesic effects of ALM16 on monosodium iodoacetate induced osteoarthritis in rats

Doo Jin Choi, Soo-Im Choi, Bo-Ram Choi, Young-Seob Lee, Dae Young Lee, Geum Soog Kim

Mulberry leaf reduces inflammation and insulin resistance in type 2 diabetic mice by TLRs and insulin Signalling pathway

Simin Tian, Min Wang, Chenyue Liu, Hongbin Zhao, Baosheng Zhao

Evaluation of a mouthrinse containing guava leaf extract as part of comprehensive oral care regimen- a randomized placebo-controlled clinical trial

Namratha Nayak, Jothi Varghese, Seema Shetty, Vinutha Bhat, Tejal Durgekar, Richard Lobo, Usha Y. Nayak, Vishwanath U

Trends in the utilization of acupuncture among children in Taiwan from 2002 to 2011: a nationwide population-based study

Chieh Wang, Yu-Chen Lee, Mei-Yao Wu, Cheng-Li Lin, Mao-Feng Sun, Jaung-Geng Lin, Hung-Rong Yen

Regulatory effect of Garidisan on dysbiosis of the gut microbiota in the mouse model of ulcerative colitis induced by dextran sulfate sodium

Ling-yan Pei, Yu-shi Ke, Huan-hu Zhao, Wei-zhi Liu, Lin Wang, Chao Jia, Meng-ni Shi, Qian-hui Fu, Jian Cui, Shu-chun Li

Cytotoxic activity of crude extracts from Datura stramonium’s fungal endophytes against A549 lung carcinoma and UMG87 glioblastoma cell lines and LC-QTOF-MS/MS based metabolite profiling

Kudzanai Ian Tapfuma, Nkemdinma Uche-Okereafor, Tendani Edith Sebola, Raeesa Hussan, Lukhanyo Mekuto, Maya Mellisa Makatini, Ezekiel Green, Vuyo Mavumengwana

Standardized ethanol extract, essential oil and zerumbone of Zingiber zerumbet rhizome suppress phagocytic activity of human neutrophils

  • Open Access
  • Research article

Nabilah Mohammad Yaqoob Akhtar, Ibrahim Jantan, Laiba Arshad, Md. Areeful Haque

Prevalence of and attitudes towards complementary therapy use for weight after breast cancer in Australia: a national survey

Carolyn Ee, Adele Elizabeth Cave, Dhevaksha Naidoo, John Boyages

The ameliorative effect of monotropein, astragalin, and spiraeoside on oxidative stress, endoplasmic reticulum stress, and mitochondrial signaling pathway in varicocelized rats

Keshab Kumar Karna, Bo Ram Choi, Jae Hyung You, Yu Seob Shin, Wan Shou Cui, Sung Won Lee, Ji Hoon Kim, Chul Young Kim, Hye Kyung Kim, Jong Kwan Park

Thymoquinone-loaded lipid vesicles: a promising nanomedicine for psoriasis

Poonam Negi, Ishita Sharma, Chetna Hemrajani, Charul Rathore, Alpna Bisht, Kaisar Raza, O. P. Katare

Constructing a bilingual website with validated database for Herb and Western medicine interactions using Ginseng, Ginkgo and Dong Quai as examples

  • Open Access
  • Database

Chang-Shiann Wu, Yu-Huai Chen, Chi-Liang Chen, Sheng-Kan Chien, Nailis Syifa, Yu-Chun Hung, Kai-Jen Cheng, Shu-Chin Hu, Pei-Tzu Lo, Shun-Yung Lin, Tzu-Hua Wu

Randomized, double-blind, placebo-controlled phase I dose escalation study of Dan Qi Tong Mai tablet in healthy volunteers

Zhong-ping Gou, Wei Zhang, Xiu-fang Liang, Ying Wang, Ju-hong Mou, Mei Li, Ya Zhang, Ping Feng

Tong-Xie-Yao-Fang improves intestinal permeability in diarrhoea-predominant irritable bowel syndrome rats by inhibiting the NF-κB and notch signalling pathways

Qiuke Hou, Yongquan Huang, Zhaoyang Zhu, Liu Liao, Xinlin Chen, Quanbin Han, Fengbin Liu

1α, 25-dihydroxy Vitamin D3 containing fractions of Catharanthus roseus leaf aqueous extract inhibit preadipocyte differentiation and induce lipolysis in 3T3-L1 cells

  • Open Access
  • Obesity
  • Research article

Anuj Kumar Borah, Archana Singh, Rafika Yasmin, Robin Doley, Venkata Satish Kumar Mattaparthi, Sougata Saha

Ameliorative effects of aqueous extract of Forsythiae suspensa fruits on oxaliplatin-induced neurotoxicity in vitro and in vivo

  • Open Access
  • Research article

Jin-Mu Yi, Sarah Shin, No Soo Kim, Ok-Sun Bang

Antitumor and antioxidant effects of Clinacanthus nutans Lindau in 4 T1 tumor-bearing mice

  • Open Access
  • Research article

Nik Mohd Afizan Nik Abd Rahman, M. Y. Nurliyana, M. N. F. Natasha Nur Afiqah, Mohd Azuraidi Osman, Muhajir Hamid, Mohd Azmi Mohd Lila

Use of traditional and complementary medicine among Norwegian cancer patients in the seventh survey of the Tromsø study

  • Open Access
  • Research article

Agnete Egilsdatter Kristoffersen, Trine Stub, Ann Ragnhild Broderstad, Anne Helen Hansen

The mycelium of the Trametes versicolor (Turkey tail) mushroom and its fermented substrate each show potent and complementary immune activating properties in vitro

Kathleen F. Benson, Paul Stamets, Renee Davis, Regan Nally, Alex Taylor, Sonya Slater, Gitte S. Jensen

Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways

  • Open Access
  • Research article

Shuping Sun, Yunyan Du, Chuanliu Yin, Xiaoguo Suo, Rui Wang, Rongping Xia, Xiaoping Zhang

Mangosteen (Garcinia mangostana) flesh supplementation attenuates biochemical and morphological changes in the liver and kidney of high fat diet-induced obese rats

  • Open Access
  • Obesity
  • Research article

Noratirah Shazlin Muhamad Adyab, Asmah Rahmat, Noor Atiqah Aizan Abdul Kadir, Hawa Jaafar, Radhiah Shukri, Nurul Shazini Ramli

Antiulcerogenic effect of Cuphea ignea extract against ethanol-induced gastric ulcer in rats

Amria M. Mousa, Nermin M. El-Sammad, Sherien K. Hassan, Abd El Nasser A. Madboli, Amani N. Hashim, Eman S. Moustafa, Sherien M. Bakry, Elsayed A. Elsayed

Experimental validation and computational modeling of anti-influenza effects of quercetin-3-O-α-L-rhamnopyranoside from indigenous south African medicinal plant Rapanea melanophloeos

Parvaneh Mehrbod, Samad Nejad Ebrahimi, Fatemeh Fotouhi, Fatemeh Eskandari, Jacobus N. Eloff, Lyndy J. McGaw, Folorunso O. Fasina

Anti-inflammatory effects of a methanol extract of Dictamnus dasycarpus Turcz. root bark on imiquimod-induced psoriasis

Minjee Choi, Jun Koo Yi, Si-Yong Kim, Jung Hyun Ryu, Jinhee Lee, Wookbong Kwon, Soyoung Jang, Dongjun Kim, MyoungOk Kim, Hyungwoo Kim, Sung Hyun Kim, Seong-Kyoon Choi, Zae Young Ryoo

Pharmacological and computational evaluation of fig for therapeutic potential in hyperactive gastrointestinal disorders

Muhammad Bilal Riaz, Arif-ullah Khan, Neelam Gul Qazi

Immunomodulatory and anti-inflammatory effects of hydro-ethanolic extract of Ocimum basilicum leaves and its effect on lung pathological changes in an ovalbumin-induced rat model of asthma

Naima Eftekhar, Ali Moghimi, Nema Mohammadian Roshan, Saeideh Saadat, Mohammad Hossein Boskabady

ACE inhibitory peptides in standard and fermented deer velvet: an in silico and in vitro investigation

Stephen R. Haines, Mark J. McCann, Anita J. Grosvenor, Ancy Thomas, Alasdair Noble, Stefan Clerens

Anti-HIV-1 protease activity of the crude extracts and isolated compounds from Auricularia polytricha

Chanin Sillapachaiyaporn, Sunita Nilkhet, Alison T. Ung, Siriporn Chuchawankul

Systems pharmacology based approach to investigate the in-vivo therapeutic efficacy of Albizia lebbeck (L.) in experimental model of Parkinson’s disease

Uzma Saleem, Zohaib Raza, Fareeha Anwar, Zunera Chaudary, Bashir Ahmad

Ethno-pharmacological survey of herbal remedies used in the treatment of paediatric diseases in Buhunga parish, Rukungiri District, Uganda

  • Open Access
  • Malaria
  • Research article

Patience Tugume, Clement Nyakoojo

Effects of fish oil supplement on psoriasis: a meta-analysis of randomized controlled trials

Shih-Jyun Yang, Ching-Chi Chi

Astragaloside IV protects against diabetic nephropathy via activating eNOS in streptozotocin diabetes-induced rats

Yuyan Fan, Hongyu Fan, Bin Zhu, Yilun Zhou, Qingshan Liu, Ping Li

The combination of Radix Astragali and Radix Angelicae Sinensis attenuates the IFN-γ-induced immune destruction of hematopoiesis in bone marrow cells

  • Open Access
  • Research article

Juan Liu, Jie Wei, Changzhi Wang, Xiaoying Meng, Hening Chen, Peiying Deng, Meiyier Huandike, Huijie Zhang, Xue Li, Limin Chai

Clinical evidence-guided network pharmacology analysis reveals a critical contribution of β1-adrenoreceptor upregulation to bradycardia alleviation by Shenxian-Shengmai

  • Open Access
  • Research article

Jiaming Gao, Taiyi Wang, Xi Yao, Weiwei Xie, Xianru Shi, Shuang He, Tao Zhao, Chunhua Wang, Yan Zhu

Oolong tea consumption and its interactions with a novel composite index on esophageal squamous cell carcinoma

  • Open Access
  • Research article

Shuang Liu, Zheng Lin, Liping Huang, Huilin Chen, Yanfang Liu, Fei He, Xiane Peng, Weilin Chen, Ruigang Huang, Wanting Lu, Huimin Yang, Zhisheng Xiang, Zhihui Zhang, Zhijian Hu

Alkaloid extract of Corydalis yanhusuo inhibits angiogenesis via targeting vascular endothelial growth factor receptor signaling

Li Wan, Yang Zhao, Qun Zhang, Guangyi Gao, Shanlan Zhang, Yong Gao, Xiaofei Chen, Xiaoping Qian

Lingguizhugan decoction attenuates doxorubicin-induced heart failure in rats by improving TT-SR microstructural remodeling

  • Open Access
  • Digoxin
  • Research article

Xueping Li, Guangmin Xu, Shujun Wei, Baocheng Zhang, Huan Yao, Yuchi Chen, Weiwei Liu, Baojia Wang, Juan Zhao, Yongxiang Gao

In vitro anti-allergic activity of Moringa oleifera Lam. extracts and their isolated compounds

Nur Zahirah Abd Rani, Endang Kumolosasi, Malina Jasamai, Jamia Azdina Jamal, Kok Wai Lam, Khairana Husain

The effectiveness of traditional Japanese medicine Goshajinkigan in irradiation-induced aspermatogenesis in mice

Kumpei Takahashi, Kenta Nagahori, Ning Qu, Miyuki Kuramasu, Yoshie Hirayanagi, Shogo Hayashi, Yuki Ogawa, Naoyuki Hatayama, Hayato Terayama, Kaori Suyama, Shuichi Hirai, Kou Sakabe, Masahiro Itoh

Efficacy and safety of oral Guanxinshutong capsules in patients with stable angina pectoris in China: a prospective, multicenter, double-blind, placebo-controlled, randomized clinical trial

Yang Li, Lei Zhang, Shuzheng Lv, Xiaozeng Wang, Jian Zhang, Xiaoxiang Tian, Yan Zhang, Bojun Chen, Dayue Liu, Jie Yang, Peikang Dong, Yunzhong Xu, Yingmin Song, Junling Shi, Lian Li, Xuechang Wang, Yaling Han

Anti-adipogenic and anti-obesity activities of purpurin in 3T3-L1 preadipocyte cells and in mice fed a high-fat diet

  • Open Access
  • Obesity
  • Research article

Woo Nam, Seok Hyun Nam, Sung Phil Kim, Carol Levin, Mendel Friedman

The pro-apoptotic effect of a Terpene-rich Annona cherimola leaf extract on leukemic cell lines

Carl Ammoury, Maria Younes, Marianne El Khoury, Mohammad H. Hodroj, Tony Haykal, Peter Nasr, Marilyne Sily, Robin I. Taleb, Rita Sarkis, Rana Khalife, Sandra Rizk

Oral and injectable Marsdenia tenacissima extract (MTE) as adjuvant therapy to chemotherapy for gastric cancer: a systematic review

Xu Zhou, Meilu Liu, Qing Ren, Weifeng Zhu, Yang Wang, Haochen Chen, Jianrong Chen

A 13-Week Repeated Oral Dose Toxicity Study of ChondroT in Sprague-Dawley Rats

  • Open Access
  • Research article

Jiwon Jeong, Kiljoon Bae, Jihoon Kim, Chanhun Choi, Changsu Na, Myeongkyu Park, Youngran Kim, Chang-Seob Seo, Seon-Jong Kim

Helminthostachys zeylanica alleviates hepatic steatosis and insulin resistance in diet-induced obese mice

  • Open Access
  • Obesity
  • Research article

Ting-Chen Chang, Hao Chiang, Yu-Heng Lai, Yu-Ling Huang, Hsiu-Chen Huang, Yu-Chih Liang, Hui-Kang Liu, Cheng Huang

Effective fraction of Bletilla striata reduces the inflammatory cytokine production induced by water and organic extracts of airborne fine particulate matter (PM2.5) in vitro

Yu-Yao Zu, Quan-Fang Liu, Shu-Xin Tian, Li-Xia Jin, Fu-Sheng Jiang, Mei-Ya Li, Bing-Qi Zhu, Zhi-Shan Ding

Treatment of migraines with Tianshu capsule: a multi-center, double-blind, randomized, placebo-controlled clinical trial

Shengyuan Yu, Ye Ran, Wei Xiao, Wenjing Tang, Jianjun Zhao, Wei Chen, Huikui Zhuang, Cun Ouyang, Hai Lin, Dequan Liu, Tongjun Chen, Hui Huang, Baoshen Wang, Yanlei Hao, Zhongrui Yan, Shike Zhao, Yanling Wang, Jinjun Ni, Chaodong Wang, Wentao Ding, Guoqian Li, Jianhua Cao, Shujuan Tian

Canscora lucidissima, a Chinese folk medicine, exerts anti-inflammatory activities by inhibiting the phosphorylation of ERK1/2 in LPS-activated macrophages

  • Open Access
  • Research article

Qiao-ling Fei, Xiao-yu Zhang, Rui-juan Qi, Yun-feng Huang, Yi-xin Han, Xi-meng Li, Run-lan Cai, Yuan Gao, Yun Qi

Alcohol extract from Vernonia anthelmintica willd (L.) seed counteracts stress-induced murine hair follicle growth inhibition

Qian Wang, Yongxin Wang, Silin Pang, Jia Zhou, Jie Cai, Jing Shang

Anti-inflammatory, analgesic and acute toxicity effects of fermented soybean

Hamidah Mohd Yusof, Norlaily Mohd Ali, Swee Keong Yeap, Wan Yong Ho, Boon Kee Beh, Soo Peng Koh, Kamariah Long, Noorjahan Banu Alitheen

Complementary medicine use among Australian patients in an acute hospital setting: an exploratory, cross sectional study

  • Open Access
  • Research article

Freya Waddington, Jenny Lee, Mark Naunton, Greg Kyle, Jackson Thomas, Gabrielle O’Kane

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