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Open Access 11-04-2024 | Bladder Cancer | ASO Author Reflections

ASO Author Reflections: Changes in the Urinary Microbiome After Transurethral Resection of Nonmuscle-Invasive Bladder Cancer: Insights from a Prospective Observational Study

Author: Aleksander Ślusarczyk, MD, PhD

Published in: Annals of Surgical Oncology | Issue 6/2024

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Excerpt

The role of the urinary microbiome in developing and course of bladder cancer remains a matter of debate. Previous investigations had primarily focused on comparing urine microbiome composition between patients with and without evidence of tumor, overlooking the specific alterations induced by the transurethral resection of the bladder tumor (TURBT).1 Additionally, the unexplored territory of the tumor-associated microbiome remains understudied and its comparison to the microbiome detected in urine requires further studies, also regarding the urine method collection.2,3 Our study addressed the changes in the urinary microbiome after transurethral resection of non-muscle-invasive bladder cancer (NMIBC) and the characteristics of tumor tissue microbiome.4
Literature
2.
go back to reference Mansour B, Monyók Á, Makra N, Gajdács M, Vadnay I, Ligeti B, et al. Bladder cancer-related microbiota: examining differences in urine and tissue samples. Sci Rep. 2020;10(1):11042.CrossRefPubMedPubMedCentral Mansour B, Monyók Á, Makra N, Gajdács M, Vadnay I, Ligeti B, et al. Bladder cancer-related microbiota: examining differences in urine and tissue samples. Sci Rep. 2020;10(1):11042.CrossRefPubMedPubMedCentral
3.
go back to reference Pederzoli F, Ferrarese R, Amato V, Locatelli I, Alchera E, Lucianò R, et al. Sex-specific alterations in the urinary and tissue microbiome in therapy-naïve urothelial bladder cancer patients. Eur Urol Oncol. 2020;3(6):784–8.CrossRefPubMed Pederzoli F, Ferrarese R, Amato V, Locatelli I, Alchera E, Lucianò R, et al. Sex-specific alterations in the urinary and tissue microbiome in therapy-naïve urothelial bladder cancer patients. Eur Urol Oncol. 2020;3(6):784–8.CrossRefPubMed
Metadata
Title
ASO Author Reflections: Changes in the Urinary Microbiome After Transurethral Resection of Nonmuscle-Invasive Bladder Cancer: Insights from a Prospective Observational Study
Author
Aleksander Ślusarczyk, MD, PhD
Publication date
11-04-2024
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 6/2024
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-024-15248-2
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