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Open Access 25-09-2024 | Biomarkers | Original Article

Environmental study and stress-related biomarkers modifications in a crew during analog astronaut mission EMMPOL 6

Authors: T. A. Giacon, Simona Mrakic-Sposta, G. Bosco, A. Vezzoli, Cinzia Dellanoce, M. Campisi, M. Narici, M. Paganini, B. Foing, A. Kołodziejczyk, M. Martinelli, S. Pavanello

Published in: European Journal of Applied Physiology

Abstract

Purpose

Human presence in space is increasingly frequent, but we must not forget that it is a hostile environment. We aimed to study the characteristics of experimental scenarios, to obtain data on human response to isolation, disruption of circadian rhythm and high levels of psychophysical stress.

Methods

In these experiments, we evaluated stress response in five young healthy subjects inside an earth-based moon-settlement-like habitat during a 1-week long analog astronaut mission. Wearable devices were used to monitor daily step count of the subjects, physical activity, heart rate during physical exercise and at rest, and sleep parameters. From saliva and urine samples collected every day at awakening, we studied oxy-inflammation biomarkers and hormones (stress and appetite) were studied too.

Results

At the end of the week, all subjects revealed an increase in oxidative stress and cortisol levels but no inflammation biomarkers variations, in conjunction with increasing time/daily exercise. Furthermore, a significant decrease in hours of sleep/day, sleep quality, and REM phase of sleep was recorded and correlated with the increase of reactive oxygen species.

Conclusion

Oxidative stress increased in a short period of time and may be attributed to the influence of psychological stress during confinement, as well as increased exercise and decreased amount of sleep. On a long-term basis, this could impact performance.

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Title: Environmental study and stress-related biomarkers modifications in a crew during analog astronaut mission EMMPOL 6
Authors: T. A. Giacon
Simona Mrakic-Sposta
G. Bosco
A. Vezzoli
Cinzia Dellanoce
M. Campisi
M. Narici
M. Paganini
B. Foing
A. Kołodziejczyk
M. Martinelli
S. Pavanello
Publication date: 25-09-2024
Publisher: Springer Berlin Heidelberg
Keyword: Biomarkers
Published in: European Journal of Applied Physiology
Print ISSN: 1439-6319
Electronic ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-024-05575-3

Keynote webinar | Spotlight on modern management of frailty

Springer Medicine

Environmental study and stress-related biomarkers modifications in a crew during analog astronaut mission EMMPOL 6

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on modern management of frailty

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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