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17-06-2024 | AV Reentrant Tachycardia | ORIGINAL RESEARCH

Distribution of peak frequency and omnipolar voltage in electrograms across the atrial body and thoracic veins in a normal heart

Authors: Tomomasa Takamiya, Masateru Takigawa, Masayuki Noda, Tasuku Yamamoto, Claire Martin, Takatoshi Shigeta, Takashi Ikenouchi, Junji Yamaguchi, Miki Amemiya, Miho Negishi, Kentaro Goto, Takuro Nishimura, Susumu Tao, Shinsuke Miyazaki, Masahiko Goya, Tetsuo Sasano

Published in: Journal of Interventional Cardiac Electrophysiology

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Abstract

Background

The innovative peak frequency mapping facilitates the quantification of electrogram sharpness. However, reference values for normal atrial tissue are currently undefined. In this study, we explored the distribution of peak frequency and omnipolar peak-to-peak voltage (V-max) in a normal heart.

Methods

Twenty-two patients with structurally normal heart were included. Either the right atrium (RA) and superior vena cava (SVC) or the left atrium (LA) and pulmonary veins (PVs) were mapped during sinus rhythm.

Results

In total, 13,654 points in the RA and 4143 points in the SVC from 15 patients and 4662 points in the LA and 2761 points in PVs from 7 patients were analyzed. The correlation between peak frequency and V-max was weak (R = 0.223). The median peak frequency was larger in the SVC than in the RA (441 [358–524] Hz vs. 358 [291–441] Hz, P < 0.0001) and in PVs than in the LA (346 [253–441] Hz vs. 323 [262–397] Hz, P < 0.0001). Conversely, the median V-max was smaller in the SVC than in the RA (1.96 [0.77–3.75] mV vs. 4.11 [2.10–6.83] mV, P < 0.0001) and in PVs than in the LA (1.16 [0.33–3.17] mV vs. 4.42 [2.63–6.84] mV, P < 0.0001). More than 95% of peak frequencies were > 174 Hz in the RA and > 185 Hz in the LA, and > 95% of V-maxes were > 0.52 and > 1.07 mV in the RA and LA, respectively.

Conclusion

Given the limited correlation between peak frequency and V-max, and recognizing their potential to provide distinct information, they can be used complementarily. Employing these parameters to extract varied insights can provide comprehensive understandings of tissue characteristics.

Graphical abstract

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Metadata
Title
Distribution of peak frequency and omnipolar voltage in electrograms across the atrial body and thoracic veins in a normal heart
Authors
Tomomasa Takamiya
Masateru Takigawa
Masayuki Noda
Tasuku Yamamoto
Claire Martin
Takatoshi Shigeta
Takashi Ikenouchi
Junji Yamaguchi
Miki Amemiya
Miho Negishi
Kentaro Goto
Takuro Nishimura
Susumu Tao
Shinsuke Miyazaki
Masahiko Goya
Tetsuo Sasano
Publication date
17-06-2024
Publisher
Springer US
Published in
Journal of Interventional Cardiac Electrophysiology
Print ISSN: 1383-875X
Electronic ISSN: 1572-8595
DOI
https://doi.org/10.1007/s10840-024-01845-4
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