Skip to main content

Advanced Search

Projected result for your current search:: 0

Search Operators:

You can use operators in your search query to narrow down your results even more. Click on the search operator to see an explanation of how it works.
Finds documents with exactly this word group, in exactly this word order and spelling (e.g. "employer branding").
Finds documents with both search terms (e.g. sales AND bonus).
Finds documents with one or the other search term (e.g. porsche OR volkswagen).
Finds documents with all search terms. Blank space is understood as AND (e.g. man robot production).
Finds documents with no appearance of the word behind NOT (e.g. ford NOT "harrison ford").
Finds documents where the search term is mentioned at least "n" times."n" may be any number (e.g. COUNT(gear)>8).
Finds documents with both search terms in any word order, permitting "n" words as a maximum distance between them. Best choose between 15 and 30 (e.g. NEAR(recruit, professionals, 20)).
Finds documents with the search term in word versions or composites. The asterisk * marks whether you wish them BEFORE, BEHIND, or BEFORE and BEHIND the search term (e.g. lightweight*, *lightweight, *lightweight*).
Finds documents with the search term in different spellings. "?" allows only one character (e.g. organi?ation).
Special characters are understood as AND (e.g. Miller Bros. & Sons).
 Log in
Top
Current Cardiology Reports

Left Atrial Coupling Index for the Prediction of Atrial Fibrillation and Heart Failure: Current Evidence and Clinical Implications

Published in:
Authors
Tea Gegenava
Stephan Milhorini Pio
Koen Nieman
Published in
Current Cardiology Reports | Issue 1/2025

Abstract

Purpose of Review

The aim of this review paper is to explore the clinical utility of left atrial coupling indices—LACI-v/m (volumetric/mechanical) and LACI-av (atrioventricular volumetric)—as emerging predictors of atrial fibrillation (AF) and heart failure (HF). It emphasizes their relevance in the context of diastolic dysfunction and left heart remodeling.

Recent Findings

LACI-v/m, calculated by dividing indexed left atrial volume by a′ velocity, has been independently associated with incident AF and HF across diverse populations. LACI-av, defined as the ratio of left atrium (LA) to left ventricular (LV) end-diastolic volumes, is applicable in AF and has demonstrated predictive value for AF, HF, and mortality using echocardiography, cardiac MRI, and CT. A meta-analysis confirmed a significant association between elevated LACI and AF risk.

Summary

Given the interdependence of LA and LV function, both LACI-v/m and LACI-av enhance cardiovascular risk stratification by integrating left atrial structure and function. Future prospective studies are needed to validate standardized thresholds and guide LACI-based management strategies.
Title
Left Atrial Coupling Index for the Prediction of Atrial Fibrillation and Heart Failure: Current Evidence and Clinical Implications
Authors
Tea Gegenava
Stephan Milhorini Pio
Koen Nieman
Publication date
01-12-2025
Publisher
Springer US
Published in
Current Cardiology Reports / Issue 1/2025
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-025-02315-7
This content is only visible if you are logged in and have the appropriate permissions.

Other articles of this Issue 1/2025

Current Status of Cardiovascular Disease in Asian Americans: One Size Does Not Fit All

  • Arterial Diseases
  • Women and Cardiovascular Health (N Goldberg and S Lewis, Section Editors)

In-Stent Restenosis: Incidence, Mechanisms, and Treatment Options

Evidence-based Management of Heart Failure in the Systemic Right Ventricle

  • Heart Failure
  • Congenital Heart Disease (RA Krasuski and G Fleming, Section Editors)

Advancing Myocarditis Research: Evaluating Animal Models for Enhanced Pathophysiological Insights

  • Myocarditis
  • Myocardial Disease (A Abbate and M Merlo, Section Editors)

To Extract or not To Extract? Navigating Lead Failure in Cardiac Devices

  • Pacemaker
  • Invasive Electrophysiology and Pacing (EK Heist and S Nedios, Section Editors)

Sepsis-Associated Cardiomyopathy: Long-Term Prognosis, Management, and Guideline-Directed Medical Therapy

  • Septicemia
  • Cardiovascular Critical Care (A Higgins and G Dahiya, Section Editors)

Next-generation MRI contrast agents: preparing the field (Link opens in a new window)

New MRI contrast agents are reshaping diagnostic imaging, promising lower gadolinium exposure amid evolving practice guidelines. How can you optimise contrast selection, dosing, and patient care in this rapidly advancing field?

This content is intended for healthcare professionals outside of the UK.

Independent Medical Education Grant:
  • Bayer HealthCare Pharmaceuticals Inc.
Learn more Link opens in a new window
Image Credits
Abstract graphic of layered, concentric circular shapes in bright green, pink, blue, and purple on a dark blue background. The rings and segments form a complex radial pattern without text/© Springer Health+ IME