Skip to main content
Top
Published in:

01-08-2024 | Atrial Fibrillation | Review

Contemporary Approaches And Treatment Strategies To Avoid Esophageal Injury During Atrial Fibrillation Ablation

Author: Emile G. Daoud

Published in: Current Cardiovascular Risk Reports | Issue 10/2024

Login to get access

Abstract

Purpose of Review

The purpose of this review is to summarize the clinical data regarding methods of avoiding and protecting the esophagus from injury during ablation of atrial fibrillation (AF).

Recent Findings

For >15 years, the primary method to avoid esophageal injury has been monitoring luminal esophageal temperature (LET), even though numerous studies report several limitations to this technique. For the past several years, two devices have been used to deviate the esophagus so to increase the distance of the esophagus from the ablation energy source and thus avoid esophageal injury. However, these devices are not FDA approved. In 2023, however, two devices did achieve FDA approval for reduction of ablation-related esophageal injury. The first device uses vacuum suction and deviation and thus moves an entire segment either to the right or left, as well as incorporating LET monitoring. The second device is inserted into the esophagus, inflated and then uses a closed loop system to pump cool distilled water at 4°C.

Summary

For every AF ablation procedure, a primary concern for electrophysiologists is to avoid esophageal injury, yet despite focused attention and advances in technology, the rate of atrioesophageal fistula and major morbidity related to esophageal injury continues. When considering the expanding number of AF ablations (>900,000 worldwide), even a low percentage of complications represents a large number of patients impacted by this complication. With the development of approved esophageal protection devices, it is prudent to implement a standardized method to avoid esophageal injury which provides greater confidence of safe AF ablation.
Literature
1.
go back to reference Aryana A, Arthur A, O’Neill PG, D’Avila A. Catastrophic manifestations of air embolism in a patient with atrio-esophageal fistula following minimally invasive surgical ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2013;24:933–4.CrossRefPubMed Aryana A, Arthur A, O’Neill PG, D’Avila A. Catastrophic manifestations of air embolism in a patient with atrio-esophageal fistula following minimally invasive surgical ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2013;24:933–4.CrossRefPubMed
2.
go back to reference Stockigt F, Schrickel JW, Andrie R, Lickfett L. Atrio-esophageal fistula after cryoballoon pulmonary vein isolation. J Cardiovasc Electrophysiol. 2012;12:1254–7.CrossRef Stockigt F, Schrickel JW, Andrie R, Lickfett L. Atrio-esophageal fistula after cryoballoon pulmonary vein isolation. J Cardiovasc Electrophysiol. 2012;12:1254–7.CrossRef
3.
go back to reference Giacomino BD, Worden N, Marchigiani R, Keech J, Giudici MC. Pericardial-esophageal fistula complicating cryoballoon ablation for refractory atrial fibrillation. HeartRhythm Case Rep. 2017;3:2–6.CrossRefPubMedPubMedCentral Giacomino BD, Worden N, Marchigiani R, Keech J, Giudici MC. Pericardial-esophageal fistula complicating cryoballoon ablation for refractory atrial fibrillation. HeartRhythm Case Rep. 2017;3:2–6.CrossRefPubMedPubMedCentral
4.
go back to reference Metzner A, Burchard A, Wohlmuth P, et al. Increased incidence of esophageal thermal lesions using the second-generation 28mm cryoballoon. Circ Arrhythm Electrophysiol. 2013;6(4):769–75.CrossRefPubMed Metzner A, Burchard A, Wohlmuth P, et al. Increased incidence of esophageal thermal lesions using the second-generation 28mm cryoballoon. Circ Arrhythm Electrophysiol. 2013;6(4):769–75.CrossRefPubMed
5.
go back to reference Borchert B, Lawrenz T, Hansky B, Stellbrink C. Lethal atrioesophageal fistula after pulmonary vein isolation using high intensity focused ultrasound (HIFU). Heart Rhythm. 2008;5:145–8.CrossRefPubMed Borchert B, Lawrenz T, Hansky B, Stellbrink C. Lethal atrioesophageal fistula after pulmonary vein isolation using high intensity focused ultrasound (HIFU). Heart Rhythm. 2008;5:145–8.CrossRefPubMed
6.
go back to reference Schmidt M, Nölker G, Marschang H, et al. Incidence of oesophageal wall injury post-pulmonary vein antrum isolation for treatment of patients with atrial fibrillation. Europace. 2008;10:205–9.CrossRefPubMed Schmidt M, Nölker G, Marschang H, et al. Incidence of oesophageal wall injury post-pulmonary vein antrum isolation for treatment of patients with atrial fibrillation. Europace. 2008;10:205–9.CrossRefPubMed
7.
go back to reference Arbelo E, Brugada J, Lundqvist CB, et al. Contemporary management of patients undergoing atrial fibrillation ablation: in-hospital and 1-year follow-up findings from the ESC-EHRA atrial fibrillation ablation long-term registry. Eur Heart J. 2017;38:1302–16. Arbelo E, Brugada J, Lundqvist CB, et al. Contemporary management of patients undergoing atrial fibrillation ablation: in-hospital and 1-year follow-up findings from the ESC-EHRA atrial fibrillation ablation long-term registry. Eur Heart J. 2017;38:1302–16.
8.
go back to reference Cappato R, Calkins H, Chen SA, et al. Updated worldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillation. Circ Arrhythm Electrophysiol. 2010;3:32–8.CrossRefPubMed Cappato R, Calkins H, Chen SA, et al. Updated worldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillation. Circ Arrhythm Electrophysiol. 2010;3:32–8.CrossRefPubMed
9.
go back to reference Deneke T, Müller P, Halbfass P, et al. Effect of different ablation settings on acute complications using the novel irrigated multipolar radiofrequency ablation catheter (nMARQ). J Cardiovasc Electrophysiol. 2015;26:1063–8.CrossRefPubMed Deneke T, Müller P, Halbfass P, et al. Effect of different ablation settings on acute complications using the novel irrigated multipolar radiofrequency ablation catheter (nMARQ). J Cardiovasc Electrophysiol. 2015;26:1063–8.CrossRefPubMed
10.
go back to reference Black-Maier E, Pokorney SD, Barnett AS, et al. Risk of atrioesophageal fistula formation with contact force–sensing catheters. Heart Rhythm. 2017;14:1328–33.CrossRefPubMed Black-Maier E, Pokorney SD, Barnett AS, et al. Risk of atrioesophageal fistula formation with contact force–sensing catheters. Heart Rhythm. 2017;14:1328–33.CrossRefPubMed
11.
go back to reference Halbfass P, Nentwich K, Krug J, et al. Impact of surround flow catheter tip irrigation in contact force ablation on the incidence of asymptomatic oesophageal lesions after atrial fibrillation ablation: a prospective comparative study. Europace. euw119. https://doi.org/10.1093/europace/euw119 Halbfass P, Nentwich K, Krug J, et al. Impact of surround flow catheter tip irrigation in contact force ablation on the incidence of asymptomatic oesophageal lesions after atrial fibrillation ablation: a prospective comparative study. Europace. euw119. https://​doi.​org/​10.​1093/​europace/​euw119
19.
go back to reference Halbfass P, Müller P, Nentwich K, et al. Incidence of asymptomatic oesophageal lesions after atrial fibrillation ablation using an oesophageal temperature probe with insulated thermocouples: a comparative controlled study. Europace. 2016;19:385–91. Halbfass P, Müller P, Nentwich K, et al. Incidence of asymptomatic oesophageal lesions after atrial fibrillation ablation using an oesophageal temperature probe with insulated thermocouples: a comparative controlled study. Europace. 2016;19:385–91.
20.
go back to reference Cummings JE, Schweikert RA, Saliba WI, et al. Assessment of temperature, proximity, and course of the esophagus during radiofrequency ablation within the left atrium. Circulation. 2005;112(4):459–64.CrossRefPubMed Cummings JE, Schweikert RA, Saliba WI, et al. Assessment of temperature, proximity, and course of the esophagus during radiofrequency ablation within the left atrium. Circulation. 2005;112(4):459–64.CrossRefPubMed
21.
go back to reference Müller P, Dietrich JW, Halbfass P, et al. Higher incidence of esophageal lesions after ablation of atrial fibrillation related to the use of esophageal temperature probes. Heart Rhythm. 2015;12:1464–9.CrossRefPubMed Müller P, Dietrich JW, Halbfass P, et al. Higher incidence of esophageal lesions after ablation of atrial fibrillation related to the use of esophageal temperature probes. Heart Rhythm. 2015;12:1464–9.CrossRefPubMed
22.
go back to reference Nakagawa H, Seres KA, Jackman WM. Limitations of esophageal temperature-monitoring to prevent esophageal injury during atrial fibrillation ablation. Circ Arrhythm Electrophysiol. 2008;1(3):150–2.CrossRefPubMed Nakagawa H, Seres KA, Jackman WM. Limitations of esophageal temperature-monitoring to prevent esophageal injury during atrial fibrillation ablation. Circ Arrhythm Electrophysiol. 2008;1(3):150–2.CrossRefPubMed
23.
go back to reference Sommer P, Hindricks G. Prevention of oesophageal injury during catheter ablation of atrial fibrillation: is monitoring of oesophageal temperature the solution? Europace. 2010;12(7):911–2.CrossRefPubMed Sommer P, Hindricks G. Prevention of oesophageal injury during catheter ablation of atrial fibrillation: is monitoring of oesophageal temperature the solution? Europace. 2010;12(7):911–2.CrossRefPubMed
26.
go back to reference Rillig A, Meyerfeldt U, Birkemeyer R, et al. Oesophageal temperature monitoring and incidence of oesophageal lesions after pulmonary vein isolation using a remote robotic navigation system. Europace. 2010;12:655–61.CrossRefPubMed Rillig A, Meyerfeldt U, Birkemeyer R, et al. Oesophageal temperature monitoring and incidence of oesophageal lesions after pulmonary vein isolation using a remote robotic navigation system. Europace. 2010;12:655–61.CrossRefPubMed
29.
go back to reference Daoud EG, Hummel JD, Houmsse M, et al. Comparison of computed tomography imaging with intraprocedural contrast esophagram: implications for catheter ablation of atrial fibrillation. Heart Rhythm. 2008;5(7):975–80.CrossRefPubMed Daoud EG, Hummel JD, Houmsse M, et al. Comparison of computed tomography imaging with intraprocedural contrast esophagram: implications for catheter ablation of atrial fibrillation. Heart Rhythm. 2008;5(7):975–80.CrossRefPubMed
30.
go back to reference Di Biase L, Saenz LC, Burkhardt DJ, et al. Esophageal capsule endoscopy after radiofrequency catheter ablation for atrial fibrillation: documented higher risk of luminal esophageal damage with general anesthesia as compared with conscious sedation. Circ Arrhythm Electrophysiol. 2009;2:108–12.CrossRefPubMed Di Biase L, Saenz LC, Burkhardt DJ, et al. Esophageal capsule endoscopy after radiofrequency catheter ablation for atrial fibrillation: documented higher risk of luminal esophageal damage with general anesthesia as compared with conscious sedation. Circ Arrhythm Electrophysiol. 2009;2:108–12.CrossRefPubMed
31.
go back to reference Joza J, Nair GM. BirnieDH, Nery PB, Redpath CJ, Sarrazin JF: High-power short-duration versus low-power long-duration ablation for pulmonary vein isolation: A substudy of the AWARE randomized controlled trial. J Cardiovasc Electrophysiol. 2024;1:136–45. https://doi.org/10.1111/jce.16123.CrossRef Joza J, Nair GM. BirnieDH, Nery PB, Redpath CJ, Sarrazin JF: High-power short-duration versus low-power long-duration ablation for pulmonary vein isolation: A substudy of the AWARE randomized controlled trial. J Cardiovasc Electrophysiol. 2024;1:136–45. https://​doi.​org/​10.​1111/​jce.​16123.CrossRef
32.
go back to reference List S, Meinhardt C, Mueller J, Deneke T, Barth S, Waechter C, et al. Incidence of ablation-induced esophageal lesions and gastroparesis in patients undergoing ablation index guided high power short duration atrial fibrillation ablation. J Cardiovasc Electrophysiol. 2023;1:82–9. https://doi.org/10.1111/jce.15731.CrossRef List S, Meinhardt C, Mueller J, Deneke T, Barth S, Waechter C, et al. Incidence of ablation-induced esophageal lesions and gastroparesis in patients undergoing ablation index guided high power short duration atrial fibrillation ablation. J Cardiovasc Electrophysiol. 2023;1:82–9. https://​doi.​org/​10.​1111/​jce.​15731.CrossRef
35.
go back to reference Barbhaiya CR, Kogan EV, Jankelson L, et al. Esophageal temperature dynamics during high-power short-duration posterior wall ablation. Heart Rhythm. 2020;17:721–7.CrossRefPubMed Barbhaiya CR, Kogan EV, Jankelson L, et al. Esophageal temperature dynamics during high-power short-duration posterior wall ablation. Heart Rhythm. 2020;17:721–7.CrossRefPubMed
38.
go back to reference Reddy VY, Neuzil P, Koruth JS, et al. Pulsed field ablation for pulmonary vein isolation in atrial fibrillation. J Am Coll Cardiol. 2019;3:315–26.CrossRef Reddy VY, Neuzil P, Koruth JS, et al. Pulsed field ablation for pulmonary vein isolation in atrial fibrillation. J Am Coll Cardiol. 2019;3:315–26.CrossRef
43.
48.
go back to reference Parikh V, Swarup V, Hantla J, et al. Feasibility, safety and efficacy of a novel pre-shaped nitinol esophageal deviator to successfully deflect the esophagus and ablate left atrium without esophageal temperature rise during atrial fibrillation ablation – The DEFLECT GUT study. Heart Rhythm. 2018;15(9):1321–7.CrossRefPubMed Parikh V, Swarup V, Hantla J, et al. Feasibility, safety and efficacy of a novel pre-shaped nitinol esophageal deviator to successfully deflect the esophagus and ablate left atrium without esophageal temperature rise during atrial fibrillation ablation – The DEFLECT GUT study. Heart Rhythm. 2018;15(9):1321–7.CrossRefPubMed
49.
go back to reference Bhardwaj R, Naniwadekar A, Whang W, et al. Esophageal deviation during atrial fibrillation ablation: clinical experience with a dedicated esophageal balloon retractor. JACC Clin Electrophysiol. 2018;4:1020–30.CrossRefPubMed Bhardwaj R, Naniwadekar A, Whang W, et al. Esophageal deviation during atrial fibrillation ablation: clinical experience with a dedicated esophageal balloon retractor. JACC Clin Electrophysiol. 2018;4:1020–30.CrossRefPubMed
50.
go back to reference Sink J, Nimmagadda K, Zhao M, et al. Esophageal temperature management during cryoballoon ablation for atrial fibrillation. J Cardiovasc Electrophysiol. 2022;33:2560–6.CrossRefPubMedPubMedCentral Sink J, Nimmagadda K, Zhao M, et al. Esophageal temperature management during cryoballoon ablation for atrial fibrillation. J Cardiovasc Electrophysiol. 2022;33:2560–6.CrossRefPubMedPubMedCentral
51.
go back to reference John J, Garg L, Orosey M, Desai T, Haines DE, Wong WS. The effect of esophageal cooling on esophageal injury during radiofrequency catheter ablation of atrial fibrillation. J Interv Card Electrophysiol. 2020;58:43–50.CrossRefPubMed John J, Garg L, Orosey M, Desai T, Haines DE, Wong WS. The effect of esophageal cooling on esophageal injury during radiofrequency catheter ablation of atrial fibrillation. J Interv Card Electrophysiol. 2020;58:43–50.CrossRefPubMed
52.
go back to reference Leung LWM, Bajpai A, Zuberi Z, et al. Randomized comparison of oesophageal protection with a temperature control device: results of the IMPACT study. Europace. 2021;23(2):205–15.CrossRefPubMed Leung LWM, Bajpai A, Zuberi Z, et al. Randomized comparison of oesophageal protection with a temperature control device: results of the IMPACT study. Europace. 2021;23(2):205–15.CrossRefPubMed
Metadata
Title
Contemporary Approaches And Treatment Strategies To Avoid Esophageal Injury During Atrial Fibrillation Ablation
Author
Emile G. Daoud
Publication date
01-08-2024
Publisher
Springer US
Published in
Current Cardiovascular Risk Reports / Issue 10/2024
Print ISSN: 1932-9520
Electronic ISSN: 1932-9563
DOI
https://doi.org/10.1007/s12170-024-00742-9

A quick guide to ECGs

Improve your ECG interpretation skills with this comprehensive, rapid, interactive course. Expert advice provides detailed feedback as you work through 50 ECGs covering the most common cardiac presentations to ensure your practice stays up to date. 

PD Dr. Carsten W. Israel
Developed by: Springer Medizin
Start the cases

Keynote webinar | Spotlight on medication adherence

  • Webinar | 27-06-2024 | 18:00 (CEST)

Medication non-adherence is a major barrier to effective healthcare delivery; half of all patients do not follow their doctor’s recommendations or treatment plan.

Our experts explain the fundamentals with a practical discussion of how to manage non-adherence in two common scenarios: hypertension and asthma control.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Watch now