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Published: Thursday 12th December 2024
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Critical Care
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Open Access 01-12-2024 | Matters Arising

Association between whole blood transfusion and mortality

Author: Shangzhong Chen

Published in: Critical Care | Issue 1/2024

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Excerpt

In a recent study [1], Dr. Aoki and his colleagues investigated the association between whole blood ratio (WBR: whole blood volume/total blood volume) and the risk of mortality in trauma patients requiring massive blood transfusion. To adjust for potential confounders, multivariable logistic regression analysis with generalized estimating equations was adopted. The results showed that a higher proportion of whole blood transfusions was associated with an increased probability of survival in trauma patients undergoing massive transfusions. These findings suggest that a liberal use of whole blood transfusion could be beneficial for resuscitating trauma patients in need of extensive transfusion support. However, certain details merit careful consideration when interpreting and applying these findings. …
Literature
1.
Aoki M, Abe T, Komori A, Katsura M, Matsushima K. Association between whole blood ratio and risk of mortality in massively transfused trauma patients: retrospective cohort study. Crit Care. 2024;28(1):253.CrossRefPubMedPubMedCentral
2.
Baucom MR, Price AD, Whitrock JN, Hanseman D, Smith MP, Pritts TA, Goodman MD. Need for blood transfusion volume is associated with increased mortality in severe traumatic brain injury. J Surg Res. 2024;301:163–71.CrossRefPubMed
3.
Loudon AM, Rushing AP, Hue JJ, Ziemak A, Sarode AL, Moorman ML. When is enough enough? Odds of survival by unit transfused. J Trauma Acute Care Surg. 2023;94(2):205–11.CrossRefPubMed
Metadata
Title
Association between whole blood transfusion and mortality
Author
Shangzhong Chen
Publication date
01-12-2024
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2024
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-024-05184-8

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