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Open Access 26-12-2023 | Ascites | Original Article

MRI findings of malignant transformation arising from mature cystic teratoma of the ovary: comparison with benign mature cystic teratoma

Authors: Masaya Kawaguchi, Hiroki Kato, Tatsuro Furui, Yoshifumi Noda, Fuminori Hyodo, Tatsuhiko Miyazaki, Masayuki Matsuo

Published in: Japanese Journal of Radiology | Issue 5/2024

Abstract

Objective

This study aimed to evaluate the efficacy of MRI findings to differentiate malignant transformation arising from mature cystic teratoma (MT-MCT) of the ovary from benign mature cystic teratoma (BMCT).

Materials and methods

This study included 11 patients with histopathologically proven MT-MCT and 50 with BMCT. Overall, 7 patients with MT-MCT and all 50 with BMCT underwent unenhanced and contrast-enhanced MRIs and 4 with MT-MCT only underwent unenhanced MRIs. The MRI findings were evaluated and compared between the two diseases.

Results

The median age (55 vs. 38 years, p < 0.01) and maximum diameter (109 vs. 65 mm, p < 0.01) were higher in MT-MCT than in BMCT. Fat component occupancy was lower in MT-MCT than in BMCT (median, 5% vs. 63%, p < 0.01). Only MT-MCT exhibited irregular tumor margins (64%), peritoneal dissemination (18%), and abnormal ascites (27%). The solid components were more commonly observed in MT-MCT than in BMCT (100% vs. 32%, p < 0.01) on contrast-enhanced images. The maximum diameter of solid components in MT-MCT was larger than that in BMCT (median, 61 mm vs. 14 mm, p < 0.01). In MT-MCT, the common configuration of solid components was endophytic or exophytic sessile (85%), whereas in BMCT, it was endophytic papillary (88%).

Conclusion

Compared with BMCT, MT-MCT demonstrated a larger maximum diameter, lower occupancy rate of fat components, and sessile solid components. The characteristic configuration of solid components was endophytic or exophytic sessile in MT-MCT and endophytic papillary in BMCT.

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Title: MRI findings of malignant transformation arising from mature cystic teratoma of the ovary: comparison with benign mature cystic teratoma
Authors: Masaya Kawaguchi
Hiroki Kato
Tatsuro Furui
Yoshifumi Noda
Fuminori Hyodo
Tatsuhiko Miyazaki
Masayuki Matsuo
Publication date: 26-12-2023
Publisher: Springer Nature Singapore
Keywords: Ascites
Teratoma
Published in: Japanese Journal of Radiology / Issue 5/2024
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI: https://doi.org/10.1007/s11604-023-01521-z

EASD 2024

Springer Medicine

MRI findings of malignant transformation arising from mature cystic teratoma of the ovary: comparison with benign mature cystic teratoma

Abstract

Objective

Materials and methods

Results

Conclusion

EASD 2024

Springer Medicine

Abstract

Objective

Materials and methods

Results

Conclusion

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