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Combining ixekizumab with tirzepatide offers additive clinical benefits over ixekizumab alone in the treatment of psoriatic arthritis in patients with overweight or obesity.
Patients with ARDs have a significantly increased risk for stroke. Review the epidemiology, pathophysiological mechanisms, clinical characteristics, prevention strategies, and post-stroke rehabilitation in this patient population.
Autoimmune-related dry eye disease is often refractory to conventional first-line treatments, with anti-inflammatory and immunomodulatory therapies instead crucial for long-term control. This stepwise approach provides insights from real-world cases.
Early detection of arthritis is critical to prevent irreversible damage. Joint ultrasound offers high sensitivity and availability in routine clinical practice, but it has limitations. Could infrared thermography play a role?
Juvenile idiopathic arthritis-associated uveitis is an important cause of childhood and adult visual impairment. Discover recent developments in disease stratification, imaging, pharmacologic management, and psychosocial support.
The first report of late-onset axial spondyloarthritis presenting with fever of unknown origin. Physicians need to be aware of rare manifestations of ax-SpA in the elderly population.
A reminder to consider methotrexate as a potential cause of gynecomastia, even with long-term low-dose therapy and in euhormonal states. Conservative measures such as dose reduction or folate supplementation may lead to symptom reversal.
A unique case of both MOGAD and emergent lupus developing after anti-TNF treatment in a patient with ankylosing spondylitis, highlighting the need for increased clinical awareness of the immunological consequences of TNF blockade.
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation and joint destruction. Despite the availability of various treatment options, many patients remain refractory to conventional therapies. Recent advancements in …
Osteoarticular diseases, including degenerative, inflammatory, genetic, and metabolic subtypes, cause severe physical impairment, psychological distress, and substantial economic burden globally. Current therapies often fail to halt progression or …
Autoimmune diseases result from the immune system’s inability to distinguish between self and non-self, destroying healthy tissue. T regulatory cells (Tregs) are a unique subset of CD4 + T cells, which play a crucial role in immune tolerance and …
The number of people living with cancer (cancer survivors) is growing rapidly, with major contributions from population ageing, advances in early detection, and improvement in cancer treatment [ 1 ]. In Australia alone, on average, 463 new cancer …
Rheumatoid arthritis (RA) is characterized by immune-mediated inflammation resulting in excess cardiovascular disease (CVD) risk. Increased sodium, decreased potassium intake and their ratio have been acknowledged as CVD risk modifiers, while …
Orthorexia nervosa (ON) is an atypical eating disorder marked by persistent preoccupation with consuming only ‘pure’ or healthy foods, coupled with harmful compulsive behaviors. Rheumatic and musculoskeletal diseases (RMDs) are a broad group of …